Diagnosis and treatment of canine leptospirosis due to serovar Bataviae —a case report
AbstractInfection ofLeptospira interrogans var. Bataviae in a properly vaccinated German shepherd dog and its successful clinical management are described. The dog was presented with a history of anorexia, vomiting, oliguria, melena, lethargy, and weakness. The animal had a proper history of yearly vaccination with the multicomponent vaccine. Hematology revealed leucocytosis, thrombocytopenia, granulocytosis, and anemia. Serum biochemical analysis showed elevated BUN, creatinine, ALP, total bilirubin, hypoalbuminemia, hyperglobulinemia, and lower A:G ratio. Based upon the clinical signs and blood-biochemical changes, the c...
Source: Comparative Clinical Pathology - April 13, 2019 Category: Pathology Source Type: research

The beneficial effect of equine chorionic gonadotropin hormone (eCG) on the in vitro co-culture of bovine spermatogonial stem cell with Sertoli cells
AbstractSpermatogenesis is a complex developmental process that originates from spermatogonia stem cell. This process consists of sequential, highly organized steps of cell proliferation and differentiation resulting in the generation of functional spermatozoa. Many growth factors, hormones, and cell interactions of germ cells with Sertoli cells regulate these processes, and the failure of any of the processes can lead to male infertility The aim of the present study was to determine the effects of equine chorionic gonadotropin on spermatogonial stem cell colony formation and differentiation after in vitro co-culture with ...
Source: Comparative Clinical Pathology - April 10, 2019 Category: Pathology Source Type: research

Oxidative stress and stroke: a review of upstream and downstream antioxidant therapeutic options
AbstractThe stroke is a cerebrovascular disorder and is the cause of a second mortality and long-lasting harm worldwide. It is classified into two types: hemorrhagic and ischemic stroke. Globally, 13% of cases of stroke are hemorrhagic, while the remaining 87% are ischemic. In this paper, we discuss the consideration of factors which possibly affect the effectiveness of antioxidant protection under oxygen deprivation, as well as oxidative stress. Such aspects as compartmentalization of reactive oxygen species (ROS)/reactive nitrogen species (RNS) formation and antioxidant localization, synthesis and transport of antioxidan...
Source: Comparative Clinical Pathology - April 9, 2019 Category: Pathology Source Type: research

Biochemical changes in Curimbat á subjected to transport stress and exposed to an agricultural fair
AbstractFish known as Curimbat á (Prochilodus lineatus) suffered a reduction in natural stocks due to predatory fishing and environmental deterioration; these are among the reasons for increased interest in the inclusion of this species in agricultural fairs. The aim of this study was to evaluate whether transport and exposure to an agricultural fair alters plasma biochemical parameters in curimbat ás. Blood samples were collected at 0 h (before transport), 10 h (end of transport), and 72 h (end of exposure to agricultural fair). Plasma cortisol levels increased after 72-h exposure to agricultu...
Source: Comparative Clinical Pathology - April 5, 2019 Category: Pathology Source Type: research

Investigations on the antimicrobial and wound healing activity of Ficus thonningii Blume extracts
In conclusion, 7.5% ointment prepar ation of ethyl acetateF. thonningii leaf extract could be considered as a potent herbal drug for treating wound infections. (Source: Comparative Clinical Pathology)
Source: Comparative Clinical Pathology - April 2, 2019 Category: Pathology Source Type: research

Metabolic status and ultrasound traits of reproductive tract of estrus dairy cows in early postpartum period
This study indicated that the correlation between ultrasound traits of uterus and metabolite hormones was not significant at the clean test in estrus dairy cows. Moreover, there was no relationship between serum leve l of IGF-1, NEFA, and BHBA with either dominant follicle diameter or existence of corpus luteum (CL). Significant association between ultrasound properties of the uterus and ovaries and metabolic hormone (IGF-1, NEFA, and BHBA) concentrations did not reveal in estrus dairy cows at day 28 ± 3 po stpartum. (Source: Comparative Clinical Pathology)
Source: Comparative Clinical Pathology - April 2, 2019 Category: Pathology Source Type: research

Antiulcer activity of aqueous extract of leaves of Mentha piperita in Wistar rats
In conclusion, it seems that the aqueous extract ofM. piperita can prevent gastroduodenal ulcers in rats without any side effect. (Source: Comparative Clinical Pathology)
Source: Comparative Clinical Pathology - March 16, 2019 Category: Pathology Source Type: research

Effect of two different habitat on haematological parameters of fishes of Odisha
AbstractThe aim of this study was to assess the influence of different water quality of Kausalyaganga pond of Bhubaneswar and Kalupada ghat, the northern sector of Chilika lagoon of Khordha district, Odisha on the haematological and morphometry of erythrocytes ofHeteropneustes fossilis,Clarias batrachus,Channa punctatus,Channa striatus andAnabas testudineus. In both sampling sites, water physical-chemical-parameters of the water were measured. Our results showed statistical difference in pH, alkalinity, salinity and dissolved oxygen between the two sites. Haematological parameters like haemoglobin (Hb), red blood cell coun...
Source: Comparative Clinical Pathology - March 16, 2019 Category: Pathology Source Type: research

Investigation of eucalyptus essence 1% and its mixture with licorice gel 10% on the infected third-degree burn wound in rat model
AbstractMany people have irreversible defects and to be death due to burn wounds every year. The current study was conducted to assess the effects of eucalyptus essence (EE) and its mixture with licorice in burn wound healing in rats. One hundred fifty rats were divided to five equal groups. Twenty-four hours after induction of third-degree burn wound, inoculation of 108 colony-forming units ofPseudomonas aeruginosa (PA 103) into the burnt area was performed in form of subcutaneous. Group 1 was given no treatment, and group 2 received gel base. Group 3 (positive control) was treated with silver sulfadiazine (SSD). Groups 4...
Source: Comparative Clinical Pathology - March 16, 2019 Category: Pathology Source Type: research

Griffonia simplicifolia (DC.) Baill. attenuates gentamicin and cisplatin-induced nephrotoxicty in rats
This study was designed to evaluate the nephroprotective activity of 50% hydroethanolic leaf extract ofGriffonia simplicifolia (DC.) Benth in drug-induced nephrotoxicity in Sprague –Dawley rats. Nephrotoxicity was induced in experimental animals by administering gentamicin and cisplatin after pre-treatment with hydroethanolic extract ofG. simplicifolia (GSE). GSE at 100 and 250  mg/kg were administered for 7 and 10 days by oral gavage in the gentamicin and cisplatin models, respectively. Silymarin (120 mg/kg) was given as the standard nephroprotective drug. Nephroprotective effect was studied by assayi...
Source: Comparative Clinical Pathology - March 14, 2019 Category: Pathology Source Type: research

Surgical treatment of large intestinal intussusception in a Rottweiler puppy
AbstractA 3-month Rottweiler female dog approximately weighing 5  kg was referred to veterinary clinic with history of defecation ceasing symptoms for about 48 h. In the clinical examinations, anorexia, lethargy, and frequent vomiting were observed. The blood work showed an increase in neutrophils. The mucosa was dark color and the animal CRT was increased. Acc ording to the clinical symptoms and blood work findings, a simple radiograph was considered to be taken from the abdominal cavity and the layering of gas-filled intestine was seen, which decided to take the radiograph with the contrast media. In the radiol...
Source: Comparative Clinical Pathology - March 13, 2019 Category: Pathology Source Type: research

Serum protein electrophoretic profile in diarrheic neonatal calves
AbstractThe electrophoretic profile of clinically healthy newborn calves and calves with neonatal diarrhea was compared. Blood samples were collected at 3 and 10  days of age from 11 calves that remained clinically healthy throughout the study period and 14 calves with diarrhea. A significant reduction in the gamma globulins was observed in the diarrheic calves that can be attributed to the transfer of serum immunoglobulins, to the intestinal lumen to count eract the infection. Moreover, a significant increase in the albumin was observed in this group between the sampling days that is mainly attributed to the relative...
Source: Comparative Clinical Pathology - March 12, 2019 Category: Pathology Source Type: research

Biochemical reference intervals for the Italian Heavy Draft horse
AbstractEstablished breed-specific reference intervals are important for monitoring the health status of horses. Serum biochemical breed-specific reference intervals have been evaluated in horses and other animal breeds, but there are no studies for the Italian Heavy Draft horse. The aim of this study was to determine biochemical reference intervals for the Italian Heavy Draft horse living in central Italy. Moreover, the comparison between different physiological status (pregnancy and no pregnancy) and age (foals and adults) has been executed. Inclusion criteria were established before blood collection. Blood samples were ...
Source: Comparative Clinical Pathology - March 9, 2019 Category: Pathology Source Type: research

Comparison of transduction efficiency among various cell types by a lentivector containing CMV promoter
In this study, the third-passage isolated MSCs from four different species, including ovine and goat cardiac fibroblasts, HEK293T, and L929 cell line were transduced by concentrated virus particles. Then, transduction percentage was detected by flow cytometry. The findings showed different transduction efficiencies for various cells of one species or other species, indicating that differentiated and undifferentiated cells had different transduction percentages. Different degrees of transduction observed in differentiated and undifferentiated cells might be the result of various lentiviral receptors on the plasma membrane, ...
Source: Comparative Clinical Pathology - March 4, 2019 Category: Pathology Source Type: research

The association between metabolic profile indices, clinical parameters, and ultrasound measurement of backfat thickness during the periparturient period of dairy cows
This study aimed to evaluate clinical and biochemical changes in dairy cows during periparturient period. It was carried out on 38 multiparous Holstein/Fersian crossbreed dairy cows 3 –11 years old. Using ultrasonography for measurement backfat thickness (BFT) for detection of the energy deficit. BFT on dairy cattle is used to monitor changes in subcutaneous fat thickness which represent changes in energy stores. On the basis of clinical examination and assessment of BHBA conc entration in blood, cows were classified to four groups, control healthy cows (C = 16), subclinical ketosis (SCK =&t...
Source: Comparative Clinical Pathology - March 1, 2019 Category: Pathology Source Type: research

Clinical observation, acute phase protein levels, and histopathological changes of mammary gland in experimentally infected goats with Staphylococcus aureus
AbstractStaphylococcus aureus (S. aureus) is a major cause of mastitis in small ruminants, and studies on the potential application of acute phase proteins (APPs) in disease biomarkers and understanding the disease mechanism in mastitis affecting small ruminants are limited. Thus, the objective of this study was to determine clinical, histopathological changes and serum concentrations of serum amyloid A (SAA) and haptoglobin (Hp) associated with experimentally induced mastitis usingS. aureus. Left mammary quarter in the does was challenged with sterile Ringers buffered salt solution as group 1 (control animals;n =&t...
Source: Comparative Clinical Pathology - February 27, 2019 Category: Pathology Source Type: research

Impact of environmental changes on plasma biochemistry and hematological parameters of Himalayan snow trout, Schizothorax plagiostomus
AbstractThe hematological and plasma biochemical parameter study is recognized as a valuable tool for evaluating health status, physiological and pathological conditions of fish. In the present study, blood sampling was carried out with the aim to evaluate plasma biochemistry and hematological parameters of Himalayan snow trout,Schizothorax plagiostomus, that are altered due to variation in environmental conditions. The fluctuations in hematological parameters such as hemoglobin (Hb), red blood cell (RBC) count, packed cell volume (PCV), white blood cell (WBC) count, mean corpuscular hemoglobin (MCH), mean corpuscular hemo...
Source: Comparative Clinical Pathology - February 26, 2019 Category: Pathology Source Type: research

In vitro and in vivo studies on the alpha-glucosidase inhibitory effects of the leaf extract of Carica papaya Linn
AbstractThe search for novel alpha-glucosidase inhibitory agents is currently an important scientific endeavour to the biopharmaceutical companies due to their potentials to reduce postprandial hyperglycaemia in type 2 diabetic patients. The present research attempted to investigate the alpha-glucosidase inhibitory effects of the leaf extract ofCarica papaya. Aqueous, methanol, ethyl acetate and n-hexane extracts ofC. papaya leaf were subjected to in vitro alpha-glucosidase inhibitory studies, and methanol extract was the most potent (IC50 = 171.83 ± 26.89 μg/mL). Consequently, th...
Source: Comparative Clinical Pathology - February 26, 2019 Category: Pathology Source Type: research

The effect of tramadol and meloxicam, alone and in combination on oxidative stress status in dogs
AbstractManagement of pain by different therapeutic agents has always been one of the most important components in clinical veterinary care. Concerns about various side effects of analgesics drugs have lead the pain relief to combination drug therapy. The present study was performed to evaluate the effect of combined tramadol and meloxicam on oxidative stress status in dogs. Twenty clinically healthy dogs were randomly divided into four groups and administered with placebo, tramadol, meloxicam, and combined meloxicam with tramadol for 10  days. The antioxidant enzymes (superoxide dismutase (SOD), glutathione peroxidas...
Source: Comparative Clinical Pathology - February 23, 2019 Category: Pathology Source Type: research

Ultrastructural changes on fertile and infertile hydatid cysts induced by conventional and solid lipid nanoparticles of albendazole and albendazole sulfoxide
AbstractCystic echinococcosis (CE), a serious public health problem worldwide, is caused by the larval stage ofEchinococcus granulosus (E. granulosus). Despite recent progress in the CE medical treatment, this subject still remains as a priority of research. Albendazole (ABZ) is a drug of choice for the treatment of hydatidosis. Its use as an antiparasitic agent with the most efficacy is limited by the lack of water solubility. Therefore, the aim of the present study was to compare in vitro efficacy of free and solid lipid nanoparticles (SLNs) of ABZ and albendazole sulfoxide (ABZSO) against fertile and infertile hydatid c...
Source: Comparative Clinical Pathology - February 21, 2019 Category: Pathology Source Type: research

Hematological and serum biochemical parameters of five freshwater snow trout fish species from river Jhelum of Kashmir Himalaya, India
AbstractFish blood is a pathophysiological indicator of the whole body function and is thus considered as an important tool in diagnosing the structural and functional status of fish. However, the blood parameters vary between species to species and it mainly depends upon the favorable environmental conditions where the species live. The purpose of the current study is to evaluate the hematological and serum biochemical indices of fiveSchizothorax species:Schizothorax labiatus,S. plagiostomus, S. esocinus,S. curvifrons andS. niger in order to establish the resemblances and variations between theseSchizothorax species which...
Source: Comparative Clinical Pathology - February 19, 2019 Category: Pathology Source Type: research

BOX-PCR fingerprinting for molecular typing of Salmonella enterica subsp. enterica serovar Enteritidis strains originated from humans, dairy cattle, and broiler chickens
AbstractSalmonellosis is a global zoonotic infection of domestic animals and poultry with serious consequences on public health. Globally one of the most prevalent and commonSalmonella enterica serotypes is serovar Enteritidis. Our goal in this research was a molecular characterization and evaluation of biodiversity and relatedness of different Salmonella isolates. Sixty-four Salmonella Enteritidis isolates which were gathered and cultured from various hosts and locations including dairy cows, broiler chicken, and patients with diarrhea of Tehran and Kerman provinces were typed by BOX-PCR assay. Dendrograms were produced b...
Source: Comparative Clinical Pathology - February 18, 2019 Category: Pathology Source Type: research

Influence of stanozolol administration together with resistance training on thyroid and some steroid hormones in male rats
AbstractAbuse of anabolic –androgenic steroids (AASs) can lead to numerous detrimental health effects on body systems. With the increased self-administration of these steroids during the last decades, endocrine modifications and hormonal alterations associated with them have become an important clinical issue. The purpose of this research was to study the influence of 8-week injections of different doses of stanozolol (ST) along with resistance training (RT) on the levels of thyroid and some steroid hormones. Twenty-four male Wistar rats were divided into four groups, equally: group 1, untrained + norma...
Source: Comparative Clinical Pathology - February 15, 2019 Category: Pathology Source Type: research

Gallic acid reduces inflammatory cytokines and markers of oxidative damage in a rat model of estradiol-induced polycystic ovary
AbstractHormonal disorders, oxidative stress, and inflammation in ovarian tissue cause ovulation failure in women with polycystic ovary syndrome. Considering the antioxidant properties of gallic acid (GA), the aim of this study was to investigate the effect of GA on pro-inflammatory cytokines, antioxidant enzyme activity, and DNA oxidative damage of ovarian tissue in a rat model of estradiol-induced polycystic ovary (PCO). In this experimental study, 32 female Wistar rats were divided into four groups. These included control (saline solution, orally), PCO+saline (estradiol valerate + saline solution, orally), PCO+GA50, and...
Source: Comparative Clinical Pathology - February 15, 2019 Category: Pathology Source Type: research

Pathology, isolation and characterisation of virulent and diverse Mannheimia haemolytica and Pasteurella multocida associated with fatal pneumonia in sheep, Rajasthan, India
AbstractPneumonia, a major sheep disease, causes high mortality among affected animals predominantly the lambs. It is caused by a number of microbes includingMannheimia haemolytica/Pasteurella multocida. It was aimed to explore the pathology in the lungs due to pneumonia, and to isolate and characterise the virulentM. haemolytica/P. multocida strains. The lung tissues and heart blood specimens were collected by necropsy of sheep (n = 96). These samples were used for isolation and characterisation ofM. haemolytica/P. multocida. Moreover, the fresh and square-shaped lung pieces were also taken to perform the hi...
Source: Comparative Clinical Pathology - February 15, 2019 Category: Pathology Source Type: research

Comparison of the diagnostic accuracy of markers of the acute phase of inflammation in cats. A preliminary evaluation
AbstractMarkers of acute inflammation are gaining broader acceptance in feline veterinary practice but the criteria of their diagnostic accuracy have mostly not been determined. The goal of this study was to compare the diagnostic accuracy of a variety of markers of inflammation that can be rapidly measured in everyday veterinary practice settings. White blood cell, as well as neutrophil and band cell count, degree of toxic neutrophilia, total proteins, albumin, albumin-to-globulin ratio, fibrinogen, and serum amyloid A protein were measured in 35 cats with acute inflammatory diseases and 16 control cats. The sensitivity, ...
Source: Comparative Clinical Pathology - February 9, 2019 Category: Pathology Source Type: research

Phylogenetic typing and virulence gene profile of pathogenic and commensal avian Escherichia coli in Iran: a notable finding
AbstractThe aim of this study was to compare phylogenic groups and virulence genes profiles ofEscherichia coli isolated from poultry suffering from Colibacillosis withE.coli in the intestinal flora of healthy poultry. For this purpose,var,tsh,iucd,papc,irp2, andiss virulence genes ofE. coli were investigated by multiplex PCR in 70 isolates (35 obtained from healthy samples and the other 35 isolated were attained form those with Colibacillosis) in Ardabil province, northwest of Iran. The phylogenic groups were also determined through use of PCR multiplex. Among them, 32 isolates (91%) of samples taken from poultry with Coli...
Source: Comparative Clinical Pathology - February 8, 2019 Category: Pathology Source Type: research

Multicentric intrahepatic cholangiocellular carcinoma in a budgerigar ( Melopsittacus undulatus ): a case report
AbstractCholangiocarcinoma or intrahepatic bile duct carcinoma is a malignant neoplasm of biliary epithelium which occurs mainly in wild animals rather than domestic ones. An adult 4-year-old male budgerigar was referred with symptoms of lethargy, decreased activity, and vomiting with undigested food in feces. Supportive care was tried for 3  months, but the bird did not show any signs of recovery and was finally euthanized. Necropsy revealed hepatomegaly in one lobe of the liver while the other lobe was dwindled. The remaining large lobe had a multinodular appearance with white to gray, non-umbilicated foci ranging f...
Source: Comparative Clinical Pathology - February 7, 2019 Category: Pathology Source Type: research

Histomorphogenesis on hindbrain in Huso huso ( Beluga sturgeon ) larvae
This study has been done on evolution and morphology of hindbrain structure, during larvae life from 1 to 54 dph onHuso huso. It was concentrated on significant cerebellum and medulla oblongata. The cerebellum occupied the rostral part of dorsal wall of fourth ventricle. The fourth ventricle was visible on 1  day old and by aging was majorly. The fourth ventricle lied on the caudally and continued into central canal (cc) in spinal cord. Cortex of cerebellum had three layers, which were visible from 6 days old. Granular layer of corpus cerebelli, eminentia granularis, and less valvula cerebelli contain ed Golgi ty...
Source: Comparative Clinical Pathology - February 7, 2019 Category: Pathology Source Type: research

Antidiabetic efficacies of methanolic and ethyl acetate extracts of Aristolochia ringens (Vahl) roots: in vivo comparative studies
AbstractAntidiabetic effects of methanol and ethyl acetate extracts of roots ofAristolochia ringens (Vahl) were comparatively assessed in streptozotocin (STZ)-induced rats. Pulverized root ofA. ringens was soaked with methanol, filtered, and concentrated to dryness. The resulting residue was subsequently dissolved in ethyl acetate, filtered, and concentrated to dryness to obtain ethyl acetate extract. Methanol and ethyl acetate extracts ofA. ringens root yielded 20.50  g (10.25%) and 16.4 g (8.2%) respectively. Both extracts (150 mg/kg bw) and metformin (14.2 mg/kg bw) used as reference were administere...
Source: Comparative Clinical Pathology - February 5, 2019 Category: Pathology Source Type: research

Evaluation of the serum fructosamine concentrations in transition period and its relationship with serum proteins and energy characteristics in dairy cows
AbstractThe relationship between fructosamine (FRUC) and glucose (GLU) amounts in dog was previously reported. On the other hand, no correlations were reported in transition dairy cow and late-pregnant sheep. Similar controversy also existed concerning the relationship between FRUC, albumin (ALB), and total protein (TP) concentrations. Thirty-three healthy Holstein cows were enrolled in to the study. Blood samples were obtained by jugular venipuncture at 3 and 1  weeks before and 1 and 3 weeks after calving. The concentrations of FRUC, GLU, ALB, TP, β hydroxybutyrate (BHBA), and non-esterified fatty acids (N...
Source: Comparative Clinical Pathology - February 4, 2019 Category: Pathology Source Type: research

Clinicopathological and mineral changes associated with dogs infested with Sarcoptes scabiei var. canis
AbstractThe clinicopathological features including mineral level of dogs infested withSarcoptes scabiei var.canis were evaluated to understand the pathogenesis of infestation in order to propose an effective treatment plan. Twenty healthy dogs were recruited for the study and were divided into two groups after environmental adjustments. Group A dogs were scabies free while group B dogs were housed with scabies infested dogs. The PCV, HB, RBC, WBC, platelets, lymphocytes, neutrophils, monocytes, eosinophils, TP, albumin, globulin, ALT, AST, ALP, creatinine, BUN, and glucose levels were examined for 6  weeks following e...
Source: Comparative Clinical Pathology - February 4, 2019 Category: Pathology Source Type: research

Oxidative stress and toxicity effect of Echium amoenum on mice brain
In this study, 40 mice were chosen and divided into four groups. Group (1) as control group (without injection), group (2) received 12.5  mg/kg, group (3) received 25 mg/kg, and group (4) received 50 mg/kg body weight plant.Boraginaceae was injected into mice for a month by intraperitoneal injection (i.p). Then, the mice were decapitated and brains were collected to evaluate oxidative stress. The level of lipid oxidation was significant in all groups except among high dose in comparison with control groups, and low with the intermediate dose. Changes in ion-reducing antioxidant capacity assay (CUPRAC) were n...
Source: Comparative Clinical Pathology - February 4, 2019 Category: Pathology Source Type: research

Effect of zinc on erythrocyte osmotic fragility and hemogram following chronic exposure to glyphosate-based herbicide in Wistar rats
AbstractThe study was conducted to assess the effect of zinc on erythrocyte osmotic fragility and hemogram of rats following chronic oral exposure to glyphosate-based herbicide (BUSHFIRE ®) at daily doses of 14.4–750 mg/kg of glyphosate. The erythrocyte osmotic fragility, estimated as percentage hemolysis in hypotonic saline, was significantly (p 
Source: Comparative Clinical Pathology - February 4, 2019 Category: Pathology Source Type: research

Trichostatin A (TSA) levels in response to treatment of rainbow trout with gamma-irradiated trophonts against Ichthyophthirius multifiliis
In this study, TSA levels induced by gamma-irradiated trophonts and alginate/calcium phosphate nanoparticles were measured after 30  days following treatment againstI.multifiliis in spleen, kidney, and liver tissues of rainbow trout. This sounds like TSA is an anti-parasitic enzyme that can increase in spleen, kidney, and liver tissues following treatment of rainbow trout againstI.multifiliis (P 
Source: Comparative Clinical Pathology - February 2, 2019 Category: Pathology Source Type: research

Combined effects of dietary bovine lactoferrin, Lactobacillus plantarum , and xylooligosaccharide on hemato-immunological and digestive enzymes of silvery-black porgy ( Sparidentex hasta ) fingerlings
AbstractA 6-week study was conducted to evaluate the effects of the following eight experimental diets, which varied in bovine lactoferrin (LF), xylooligosacharide (XOS), andLactobacillus plantarum (LP) as probiotic silvery-black porgy (Sparidentex hasta) juveniles including control (diet 1), 400  mg kg−1 LF + 5  g kg−1 XOS (diet 2), 400  mg kg−1 LF + 10  g kg−1 XOS (diet 3), 400  mg kg−1 LF + 1  × 106 CFU g−1 LP (diet 4), 800  mg kg−1 LF + 5  g kg−1 XOS (diet 5), 800  mg&...
Source: Comparative Clinical Pathology - February 2, 2019 Category: Pathology Source Type: research

Idiopathic nodular panniculitis of an exceptionally large size in a German Shepherd dog: a case report
AbstractAn unusual occurrence of idiopathic nodular panniculitis of an extremely large size was recognised in a German Shepherd dog. The dog was presented with a large subcutaneous nodule at the latero-ventral aspect of the abdomen on the left side of the animal. The lesion grossly appeared as a large tissue mass resembling some kind of adipose tissue tumour such as lipoma or liposarcoma. However, the histologic appearance of the tissue mass was indicative of nodular panniculitis as reflected by diffuse cellular inflammatory reaction on a wide area of adipose tissue. The cellular infiltrate was mainly dominated by lymphocy...
Source: Comparative Clinical Pathology - February 1, 2019 Category: Pathology Source Type: research

Adenosine deaminase behavior in experimental infection by Brucella ovis and its participation in the modulation of the inflammatory response
The objective of this study was to evaluate the activity of adenosine deaminase (ADA) and its participation in the modulation of the inflammatory responses of mice experimentally infected withB. ovis. We used 48 animals, divided in two groups: group A (control) and group B (infected). We evaluated ADA activity and C-reactive protein (CRP) concentrations at four time points (days 7, 15, 30, and 60) post-infection (PI). There was a reduction in ADA activity in the acute phase (day 15 PI), followed by elevation when the infection became chronic (days 30 and 60 PI). Serum C-reactive protein levels were higher in infected anima...
Source: Comparative Clinical Pathology - February 1, 2019 Category: Pathology Source Type: research

Trans-scrotal ultrasonography evaluation of the cross-bred Ongole bulls
In conclusion, trans-scrotal ultrasonography is helpful in the differential diagnosis of the scrotal swells in large animals. (Source: Comparative Clinical Pathology)
Source: Comparative Clinical Pathology - February 1, 2019 Category: Pathology Source Type: research

Diabetes upregulates the expression of HSP90 and downregulates HSP70 in the liver of diabetic rats
The objectives of the present study were to investigate the expression of Hsp90 and Hsp70 in the liver of diabetic rats and to compare it with the liver of control rats. A diabetic model was conducted using alloxan monohydrate (150  mg/kg). Immuno-histochemical staining for HSP70 and HSP90 was carried out using indirect immune-peroxidase protocol. Results showed that the expression of HSP90 in diabetic group was significantly upregulated compared with control group (p = 0.008), while the expression of HSP70 was downregulated in diabetic liver compared with control group (p = 0.000). Further...
Source: Comparative Clinical Pathology - February 1, 2019 Category: Pathology Source Type: research

Effect of Crotalaria lachnosema Stapf . (Fabaceae) extract on biomarkers of hepatic and renal function and oxidative stress in male Wistar rats
AbstractThe aim of this study was to determine the subchronic effect ofCrotalaria lachnosema Stapf. (Fabaceae) extract (MLECL) on biochemical and oxidative stress biomarkers in male Wistar rats. The rats were assigned into four groups designated as groups 1(control), 2, 3, and 4, of ten rats each, and were exposed to dose levels of 0, 40, 200, and 1000  mg of MLECL extract per kilogram in feed, respectively, for a period of 6 weeks. At the end of the study period, the surviving rats were sacrificed and blood was collected from each rat via jugular venesection and used for biochemical analysis. Postmortem examinat...
Source: Comparative Clinical Pathology - February 1, 2019 Category: Pathology Source Type: research

The effects of different doses of onion ( Allium cepa. L) extract on leptin, ghrelin, total antioxidant capacity, and performance of suckling lambs
In conclusion, it could be said that onion extract has a promising effect as a feed additive in ruminant nutrition and has the ability to improve feed intake in these animals. Moreover, onion extract has a positive effect on concentrations of leptin, ghr elin, TAC, and the performance in lambs. (Source: Comparative Clinical Pathology)
Source: Comparative Clinical Pathology - February 1, 2019 Category: Pathology Source Type: research

Light and scanning electron microscopic study of the tongue in the guinea fowl ( Numida meleagris )
AbstractConsidering that, in birds, the tongue has an important role in taking food, so its shape and morphology are affected by the nutrition method and the environment of the animal. For this study, six adult female guinea fowl were prepared and, after slaughtering them humanely, their tongues were completely removed from the oral cavity and were completely washed with distilled water. After examining the morphology and measuring the tongue area, the tissue preparation stages were used for light and electron microscopes on each case. Morphological results showed that the tongue of the guinea fowl was triangular-shaped an...
Source: Comparative Clinical Pathology - January 28, 2019 Category: Pathology Source Type: research

Medical management of conjunctivitis and shell rot in a red-eared slider ( Trachemys scripta elegans )
AbstractConjunctivitis and shell rot in a red-eared slider and its successful clinical management are described. The red-eared slider was presented to Veterinary Polyclinic Mannarkkad with swollen eyes and white patches on the carapace. The turtle was treated with enrofloxacin bath for 7  days. Superficial lesions on the carapace were treated by application of chlorhexidine gel. Three percent boric acid was used for washing the eye. Vitamin A was administered orally. Several managemental changes ware also made to hasten the recovery. After 1 week of treatment, improvement in the c ondition of eye was observed. Wi...
Source: Comparative Clinical Pathology - January 26, 2019 Category: Pathology Source Type: research

Vitamin D supplementation enhanced oral glucose tolerance in normoglycemic rats and insulin sensitivity in rats fed high fat emulsion
AbstractSeveral reports have suggested possible role of vitamin D deficiency in the pathogenesis of both type 1 and 2 diabetes. However, there is no agreement on the level of vitamin D requirement for optimum glycemic control. This work evaluated the effect of vitamin D supplementation on oral glucose tolerance (OGT) and insulin sensitivity, with the aim of determining the possible supplementation rate of vitamin D required for optimum glycemic control. Oral glucose tolerance was evaluated in normoglycemic rats, with vitamin D supplementation (VDS) at the rate of 0.07, 0.14, and 0.35  μg/kg orally for 28 days....
Source: Comparative Clinical Pathology - January 25, 2019 Category: Pathology Source Type: research

Antioxidant effects of Allium cepa and cinnamon on biochemical parameters and ultrastructure of ovarian tissue in extremely low frequency electromagnetic field exposed rats
AbstractWe investigated whether 50  Hz wave (3 mT) extremely low frequency electromagnetic field (ELF-EMF) had effect on ovarian tissue biochemical parameters and whetherAllium cepa and cinnamon can reduce potential adverse effects of electromagnetic exposure. Forty female Wistar rats were subdivided into four groups; (1) a control group received 3  cc normal saline (0.9%) daily and was treated for 6 weeks, (2) a group exposed to ELF-EMF of 3 mT for 4 h/day 7 days/week for 6 weeks, (3) a group receivedAllium cepa and cinnamon (75  mg/kg body weight) daily for 6 weeks, (4) a...
Source: Comparative Clinical Pathology - January 21, 2019 Category: Pathology Source Type: research

Health status of indigenous and exotic chickens sold in live bird markets
AbstractLive bird markets (LBMs) contain pool of various birds of different breeds, species, types, and ages, and from different sources and have been identified as impending cores of diseases ’ incubation and transmission. From the point of food safety concern, it is highly empirical to document the health status and possible disease invasion in such markets to control the market for disease-free chicken so as to ensure supply of safe food for the consumers. One hundred twenty birds co mprising of exotic and indigenous breeds of cockerels and layers were surveyed in three LBMs within Abeokuta Metropolis, Ogun State,...
Source: Comparative Clinical Pathology - January 16, 2019 Category: Pathology Source Type: research

Impairment of neuro-renal cells on exposure to cosmopolitan polluted river water followed by differential protection of Launea taraxacifolia in male rats
AbstractNeuron-nephron toxicity (NNT) has been associated with the development of Alzheimer ’s disease and mental disorders. We hypothesized that increased neuronal cholinesterase activities and oxidative stress play significant roles in kidney injury and that methanolic fraction fromLaunea taraxacifolia (LTME) could differentially promote brain-kidney wellness after sub-chronic exposure to metropolitan Surulere polluted river water (SPRW). The animals were divided into six groups (n = 8). Group I was orally given 1 ml of distilled water only; group II received 1 ml of SPRW only; group III (pr...
Source: Comparative Clinical Pathology - January 16, 2019 Category: Pathology Source Type: research

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(Source: Comparative Clinical Pathology)
Source: Comparative Clinical Pathology - January 15, 2019 Category: Pathology Source Type: research

Moringa leaf meal improves haemato-biochemical and production indices in broiler chickens: a review
AbstractThe high cost of feed materials and feed additives in developing nations has elicited interest in the search for sustainable alternatives having in mind the human food security. Moringa (Moringa oleifera), one of such sustainable alternatives, is a tropical plant with excellent nutritive and phytochemical content. It is one of the species in the family of Moringaceae and thrives well in the tropics. The excellent nutritional quality ofM. oleifera has positioned it as a choice feed ingredient/additive for broiler production. Furthermore, the high carotenoid content of moringa leaves offers great potential for its us...
Source: Comparative Clinical Pathology - January 13, 2019 Category: Pathology Source Type: research