Report of diabetes mellitus remission in a cat by orally administered glibenclamide
Abstract Clinical remission of diabetes mellitus which is one of the most commonly encountered endocrine diseases in cats is not very frequent. A 3-year-old male castrated Russian Blue cat with a history of excessive water intake and urination as well as weight loss, lethargy, and unkempt hair coat was referred to us. Type 2 diabetes mellitus was diagnosed based on clinical signs of laboratory findings in this cat. The cat was completely treated in six weeks by orally administered glibenclamide. Based on previously reported studies many factors are involved in the remission of diabetes. Most of these are due to th...
Source: Comparative Clinical Pathology - March 30, 2016 Category: Pathology Source Type: research

Evaluation of hepatic markers and body weight gain in growing and finishing steers
Conclusions These findings suggest that hepatic markers in steers are influenced by production stages and improve the knowledge about the effect of growing and finishing phases on their hepatic markers. Furthermore, it underlies the importance of monitoring body weight gain in order to obtain a maximizing profitability. (Source: Comparative Clinical Pathology)
Source: Comparative Clinical Pathology - March 30, 2016 Category: Pathology Source Type: research

The β-1,3-glucan alleviated the hepatotoxicity induced by combination of fipronil and lead in common carp ( Cyprinus carpio)
In this study, we tested the β-1,3-glucan role against fipronil and lead-induced hepatotoxicity in Cyprinus carpio. Two hundred seventy C. carpio were divided into six groups: control, β-1,3-glucan (0.1 %), fipronil (0.0428 mg/L), lead nitrate (7.3 mg/L), coadministered (fipronil and lead), and coadministered β-1,3-glucan treated. Macrocytic hypochromic anemia with significant decrease in the hepatic antioxidant activities (catalase—CAT, superoxide dismutase—SOD, and glutathione—GSH) and significant increase in the malondialdehyde (MDA) level was observed in fipronil, lead, a...
Source: Comparative Clinical Pathology - March 23, 2016 Category: Pathology Source Type: research

Changes in reduced glutathione, oxidized glutathione, and glutathione peroxidase in cats with naturally occurring chronic kidney disease
The objective of this study was to determine oxidative stress in CKD cats by measuring changes in reduced glutathione (GSH), oxidized glutathione (GSSG), glutathione peroxidase (GPx), and reduced glutathione to oxidized glutathione (GSH/GSSG) ratio in cats with naturally occurring chronic kidney disease (CKD). Thirteen clinically normal client-owned aged-matched cats and 23 naturally occurring CKD cats were included. Completed blood count, blood urea nitrogen, creatinine, GSH, GPx, GSSG, and GSH/GSSG ratio were measured on the first day of diagnosis. The results showed that CKD cats had significantly lower GSH, GPx, and GS...
Source: Comparative Clinical Pathology - March 23, 2016 Category: Pathology Source Type: research

The histomorphometric and histopathologic effect of methionine on the epidermis and dermis layers of skin in rat
Abstract The skin is the largest organ of the body and is composed of epidermis (the outermost layer of cells consisting mainly of keratinized, stratified, squamous epithelium) and dermis (a layer of connective tissue composed of cells and fibrils such as collagen bundles). The aim of this study was to assess the effect of excess methionine on the histomorphology and histomorphometry of collagen bundles in these layers. Eighty, 9–10-week old, male rats were randomly allocated into eight equal groups. Each group received one of the following treatments: L-methionine (50, 100 or 200 mg/kg B.W.), vitamin C...
Source: Comparative Clinical Pathology - March 23, 2016 Category: Pathology Source Type: research

Effects of disinfection of the umbilical cord of piglets on healing and albumin levels
The objective was to assess the effects of using drying powder and iodine solution during navel cords disinfection handling on performance and blood variables (total protein, albumin, and globulin) in newborn piglets. Four treatments were used: (1) tie, cut, and iodine (TCI); (2) tie, cut, and spread drying powder (TCDP); (3) tie, cut, iodine, and drying powder (TCIDP); and (4) no navel cord handling (NNCH). There were five sow used and from each one, eight piglets were chosen within each parturition, with two piglets by treatment (one male and one female), totaling 10 repetitions per treatment. During the first, second, a...
Source: Comparative Clinical Pathology - March 18, 2016 Category: Pathology Source Type: research

The protective effects of the methanolic root bark extract of Afzelia africana on conception and fetal development in diabetic female rats
This study was carried out to determine the protective effect of methanolic root bark extract of Afzelia africana on conception and fetal development in alloxan-induced diabetic female rats. Twenty-four female rats were used in this study and were assigned into four groups of six rats each using random sampling. Diabetes was induced in groups 1, 2, and 3 but not induced in group 4. Groups 1 and 2 were treated with 250 mg/kg of the extract and glibenclamide (2 mg/kg), respectively while groups 3 and 4 were treated with distilled water (10 ml/kg). From the study, there were significant increases (p &thi...
Source: Comparative Clinical Pathology - March 17, 2016 Category: Pathology Source Type: research

Is Wilms’ tumor gene 1 a useful biomarker for detecting minimal residual disease in chronic myeloid leukemia (BCR-ABL1-p210-positive) patients?
Abstract Chronic myeloid leukemia (CML) is a clonal hematopoietic stem cell disorder characterized by the presence of Philadelphia (Ph) chromosome. Wilms’ tumor gene 1 (WT1) plays an important role in leukemogenesis and can be useful as a molecular marker to detect minimal residual disease (MRD). The goal of this study was to evaluate WT1 expression and compare it with BCR-ABL1 expression in peripheral blood (PB) of CML patients, in order to explore the utility of WT1 as an alternative marker for MRD detection. Eighteen newly diagnosed CML patients (BCR-ABL1-p210-positive), 16 chronic CML patients with a his...
Source: Comparative Clinical Pathology - March 15, 2016 Category: Pathology Source Type: research

Blood biochemistry responses of ducks infected with a velogenic Newcastle disease virus
This study investigated the blood biochemistry responses of Pekin ducks (Anas platyrhynchos domesticus) experimentally infected with a velogenic Newcastle disease virus (NDV), KUDU 113 strain. One hundred ducklings were used for the study. The ducks were obtained at a week old and randomly divided into three groups. One group was vaccinated against NDV with La Sota vaccine at 3 weeks of age. The vaccinated and unvaccinated groups of 30 ducks each were subsequently challenged with the velogenic NDV after 6 weeks of brooding, while the control group of 40 ducks was not vaccinated and not challenged. Blood samples w...
Source: Comparative Clinical Pathology - March 10, 2016 Category: Pathology Source Type: research

Myiasis caused by Cephalopina titillator (Diptera: Oestridae) in camels ( Camelus dromedarius ) of semi-arid areas in Iran: distribution and associated risk factors
Abstract Cephalopina titillator is a common obligate parasite of camel in Africa and Asia. Camel bot fly causes severe economic losses to the camel such as reduction of milk production and fertility, diminution of physiological functions, difficulty in breathing, and tissue damage. The present study aimed to determine the prevalence and associated risk factors of C. titillator infestation in camels slaughtered in the abattoir of Yazd, center of Iran. Three hundred slaughtered camels were accurately inspected for presence of C. titillator larvae. The last abdominal ring of larvae was carefully sectio...
Source: Comparative Clinical Pathology - March 9, 2016 Category: Pathology Source Type: research

Metabolic adaptation after experimental clinical pregnancy toxemia in ewes
This study was performed to evaluate the effect of induction of clinical ketosis or pregnancy toxemia (PT) and subsequent effects on serum biochemical factors. Seven native pregnant ewes aged 3–4 years, 45–50 kg weight with BCS of 3.5–4 on a 0–5 scale were selected. The pregnancy of ewes was confirmed by ultrasound examination. Blood samples were harvested from the jugular vein before and after the induction of PT by food deprivation. Serum β-hydroxybutyrate (BHBA), Nonesterified fatty acids (NEFA), BUN, glucose, calcium, total protein, and cortisol concentrations were measured. Serum...
Source: Comparative Clinical Pathology - March 9, 2016 Category: Pathology Source Type: research

Herbal remedies against gastric cancer in experimental rats
Abstract Gastric cancer is the fourth most prevalent cancer worldwide, which claims more than 700,000 lives every year. However, the current chemical and surgical management of this mortal cancer remains far from successful. A recent safe approach to preventing or treating tumorigenesis has been the re-introduction of traditional herbal medicine, taking advantage of efficient, yet natural healthy products. In this review, we have focused on a number of such popular agents, mostly introduced by the Traditional Chinese medicine (TCM), which have exhibited highly significant preventive/therapeutic effects against var...
Source: Comparative Clinical Pathology - March 4, 2016 Category: Pathology Source Type: research

Erratum to: Postpartum pathology in Yankasa ewes experimentally infected with Trypanosoma evansi during pregnancy
(Source: Comparative Clinical Pathology)
Source: Comparative Clinical Pathology - March 3, 2016 Category: Pathology Source Type: research

Serum protein electrophoresis in Galgos
Abstract The Galgo is a member of the sighthound family and is one of the most popular breeds in Spain. Several sighthound breeds have laboratory values that are outside the reference intervals established for the general population of dogs. Serum protein electrophoresis has not been studied in Galgos and they are often interpreted as if they were Greyhounds. However, recent studies suggest that each sighthound breed presents its own specific laboratory features, and the extrapolation of the information described in Greyhounds to other sighthound breeds could lead to misdiagnoses. The aims of this study were as f...
Source: Comparative Clinical Pathology - March 1, 2016 Category: Pathology Source Type: research

Neutrophil gelatinase-associated lipocalin (NGAL) as a potential biomarker for early detection of acute renal failure
The objective of this research was to assess the ability of NGAL as a biomarker of acute renal failure by comparing the levels of serum urea and creatinine in rats with induced acute renal failure. Twelve male Wistar rats (Rattus norvegicus), 2 months of age with a body weight (BW) of 150–200 g, were allocated into two groups. Group I (n = 2), as the control group, were injected with sterile distilled water 10 mL/kg BW intramuscularly and group II (n = 10) were injected with 50 % glycerol 10 mL/kg BW intramuscular, the rats in all group had been fasting 12 h b...
Source: Comparative Clinical Pathology - March 1, 2016 Category: Pathology Source Type: research

Anesthetic effect of xylazine and benzocaine on hematological parameters and stress indicators of juvenile grass carp, Ctenopharyngodon idella (Valenciennes, 1844)
In this study, we investigated the efficacies of two anesthetics agents, xylazine and benzocaine, then compared hematological parameters and biochemical indices under optimum concentrations of two anesthetics with clove oil on juvenile grass carp, Ctenopharyngodon idella. The optimum concentrations were determined as 0.3 mg/l for xylazine and 50 mg/l for benzocaine. Significant increases in hematological parameters including white blood cell, red blood cell, and hematocrit were observed for the two anesthetics agents compared to clove oil. Plasma cortisol, glucose, and lactate concentrations increased significant...
Source: Comparative Clinical Pathology - March 1, 2016 Category: Pathology Source Type: research

The identification of bacterial flora in oral cavity of snakes
This study was carried out to determine bacterial agents existing in the oral cavity of venomous and non-venomous snakes in Kashan, Iran. Using sterile swabs, the samples were obtained in two stages from the oral cavity of 11 venomous and non-venomous snakes before feeding and 3 weeks later. Then, they were cultured on Mac Conkey blood agar mediums. Gram staining of all samples was performed. Appropriate mediums and tests were fulfilled to determine gram-positive and gram-negative bacteria. The highest rate of infection belonged to coagulase-negative Staphylococcus (34.5 %) and the lowest rate was for Pseudomonas...
Source: Comparative Clinical Pathology - March 1, 2016 Category: Pathology Source Type: research

Ontogenetic study of enteric xanthine oxidase in the chick embryos: focus on the late embryogenesis
Abstract Xanthine oxidase (XO) is a member of xanthine oxidoreductase (XOR) enzyme system that catalyses the terminal reactions of purine degradation to uric acid (UA). The synthesis of both antioxidant (i.e. UA) and numerous free radicals makes XO an important regulator of the cellular redox potential involved in normal foetal development. The aim of this study was to investigate ontogenetic changes of enteric XO activity and UA content during the last week of chick embryonic development. Fertilized eggs (n = 180) of layer-breeder (Bovans White) and broiler-breeder hens (Ross 308) were incubated at ...
Source: Comparative Clinical Pathology - February 29, 2016 Category: Pathology Source Type: research

Effect of lactation induction on milk production and composition, oxidative and antioxidant status, and biochemical variables
This study aimed to induce lactation in Lacaune sheep and to verify its influence on milk production and composition, oxidative/antioxidant profile, and biochemical variables in serum and milk. A group of ewes (group A, n = 7) was induced with estradiol (0.5 mg/kg body weight (BW)) and progesterone (1.25 mg/kg BW) on days 1 to 7, bovine somatotropin (BST; 250 mg/animal) on days 11 and 40, as well as dexamethasone (16 mg/day) on days 19, 20, and 21. For comparison, another group of pregnant ewes was used as control (group B, n = 5). Blood and milk samples were collected for bi...
Source: Comparative Clinical Pathology - February 27, 2016 Category: Pathology Source Type: research

Biochemical profiles of Indian donkey population located in six different agro-climatic zones
This study indicated that normal biochemical values of different indices for a particular population should not be used as such for disease prognosis, diagnosis and therapeutic monitoring of other donkey population belonging to other agro-climatic zone having different nutritional and managemental practices. (Source: Comparative Clinical Pathology)
Source: Comparative Clinical Pathology - February 27, 2016 Category: Pathology Source Type: research

Hematological and biochemical reference intervals for Bothrops asper and Crotalus simus (Serpentes: Viperidae), maintained in captivity for venom extraction
This study presents hematological and biochemical reference intervals (RIs) for two species of viper snakes (Bothrops asper and Crotalus simus), which are the first of their type particularly for these two species maintained in captivity and for extraction of venom purposes. A total of 77 snakes were used in developing the study; specifically 39 B. asper and 38 C. simus snakes. Blood samples were obtained by puncturing the caudal vein, and hematological tests were performed manually by two independent technicians. Plasma biochemistry parameters were determined by an automatized analyzer. There are hematological differences...
Source: Comparative Clinical Pathology - February 25, 2016 Category: Pathology Source Type: research

Haematological and acute-phase response of dogs with experimental skin Pseudomonas aeruginosa infection to treatment with antibiotic and parthenolide
Abstract Changes in white blood cells, leukogram patterns, the positive acute-phase protein (APP) fibrinogen and negative APPs (albumin and arylesterase) were monitored to evaluate their potential as sensitive indicators throughout the course of therapy in canine skin Pseudomonas aeruginosa infection. The study was performed on 15 male mixed-breed dogs, divided in three groups of 5 dogs each. Dogs from group A were injected subcutaneously with P. aeruginosa bacterial culture (1 × 108 CFU/mL) at a dose of 0.3 mL/kg and treated with enrofloxacin (5 mg/kg, s.c.) on post infection ho...
Source: Comparative Clinical Pathology - February 22, 2016 Category: Pathology Source Type: research

Antimicrobial activity of peptides derived from enzymatic hydrolysis of goat milk caseins
In this study, peptide fragments were produced from goat milk casein by proteolytic enzymes trypsin and ficin and combination of both enzymes, and their antimicrobial activity was investigated. After enzymatic treatments, antimicrobial activity against both Gram-positive and Gram-negative bacteria was enhanced. The hydrolysates were passed through ultrafiltration. The obtained hydrolysate by ficin (molecular weight (MW)
Source: Comparative Clinical Pathology - February 20, 2016 Category: Pathology Source Type: research

Case report: a rare right abomasal displacement in a feedlot bull calf
Abstract A Holstein male calf, less than 1 year old, was referred to the Veterinary Research and Teaching Hospital of University of Tehran (VRTH) with inappetence during the past 5 days and constipation. The first examination revealed depression and dehydration. Heart rate, respiratory rate, and rectal temperature were 107 bpm, 24 rpm, and 38.5 °C, respectively. Dehydration and hyperemia were observed in the mucus membranes. The feces were soft and scant with a foul odor. The contraction of rumen was weak, twice per minute. A clear tympanic and splashing sound was heard on the middle third of the right side in...
Source: Comparative Clinical Pathology - February 19, 2016 Category: Pathology Source Type: research

Glyphosate-based herbicides with different adjuvants are more potent inhibitors of 3T3-L1 fibroblast proliferation and differentiation to adipocytes than glyphosate alone
Abstract Glyphosate-based herbicides are extensively used for weed control all over the world. Thus, it is important to investigate the putative toxic effects of these commercial formulations which contain not only glyphosate but also different adjuvants. 3T3-L1 fibroblasts are a useful tool in the study of adipocyte differentiation. We have previously reported that a commercial glyphosate formulation inhibits proliferation and differentiation in these cells. In the present investigation, we further evaluated the effect of different commercial glyphosate-based herbicides on 3T3-L1 fibroblast proliferation and diff...
Source: Comparative Clinical Pathology - February 19, 2016 Category: Pathology Source Type: research

Postpartum pathology in Yankasa ewes experimentally infected with Trypanosoma evansi during pregnancy
Abstract The study was designed to determine the pathological changes in postpartum Yankasa ewes experimentally infected with Trypanosoma evansi (T. evansi) during pregnancy. Thirteen pregnant Yankasa ewes were divided into two groups comprising six ewes in group A and seven ewes in group B. Ewes in group A served as the uninfected control while ewes in group B were infected with approximately 1.0 × 106 of T. evansi per ewe through the jugular vein at the second trimester of pregnancy. They were closely monitored for trypanosomosis from the time of infection up till parturition. One ewe from ea...
Source: Comparative Clinical Pathology - February 17, 2016 Category: Pathology Source Type: research

Increased in cyclooxygenase—2 immunoreactivity and DNA damage in hippocampus of rats infected by Trypanosoma evansi
Abstract Cyclooxygenase-2 (COX-2) is one of the two isoforms of COX producing prostaglandins derived from arachidonic acid. COX-2 is the inducible isoform expressed in many cell types in response to cytokines and pro-inflammatory molecules. In brain, COX-2 is frequently associated with pro-inflammatory activities, and its increase is related to neurodegenerative processes in acute and chronic diseases. Thus, the aim of this study was to evaluate the COX-2 immunoreactivity and the frequency damage caused by T. evansi infection on days 5 and 15 post-infection (PI) in hippocampus cells, as well as the relationship wi...
Source: Comparative Clinical Pathology - February 17, 2016 Category: Pathology Source Type: research

Sensitivity and specificity of a latex agglutination test for detection of calf enterotoxigenic Escherichia coli isolates in comparison with PCR
Abstract Latex agglutination test is a very fast, accurate, and specific method that is used to diagnose antigens and antibodies which can be carried out in any place without need for any specific devices. In the present study, a single chain (scFv) recombinant monoclonal anti-K99 antibody was used in designing and producing a latex agglutination kit for the detection of enterotoxigenic Escherichia coli of calves colibacillosis. The purpose of this research was to primarily evaluate the sensitivity and specificity of the mentioned latex agglutination kit in the detection of the considered bacteria and to compare i...
Source: Comparative Clinical Pathology - February 15, 2016 Category: Pathology Source Type: research

Chemical and electrical approaches to anesthesia of Ship sturgeon, Acipenser nudiventris : induction and recovery, physiological response to anesthesia
In this study, we investigated the induction and recovery times and physiological response of juvenile Ship sturgeon, Acipenser nudiventris anesthetized by CO2 (bar), clove powder (mg/L), and available electric shock (V). The shortest and longest induction time was for electric shock and clove powder, respectively. By contrast, the shortest and longest recovery time took place for electric shock and clove powder, respectively. Cortisol and glucose levels increased in 1 and 6 h after anesthesia. Changes in plasma osmolality and hematological indices were less changed among the anesthesia treatments. Results demonstrate...
Source: Comparative Clinical Pathology - February 10, 2016 Category: Pathology Source Type: research

Congenital naso-orbital meningocele in a lamb: a case report
Abstract The subject of this report is a rare case of naso-orbital meningocele concurrent with right cerebral hemisphere hydranencephaly and agenesis of corpus callosum in a newborn lamb. Our necropsy findings revealed that the bulging sac containing CSF extends into the skull bony and dural defects, through which the cyst protrudes into the orbital and nasal cavities. Also, histological and immunohistochemical demonstrations of the cyst wall showed that the inner layer is composed of meningeal components. These findings support the diagnosis of a naso-orbital meningocele. This case is an unusual presentation of a...
Source: Comparative Clinical Pathology - February 2, 2016 Category: Pathology Source Type: research

Idiopathic pulmonary fibrosis in a captive lion ( Panthera leo ): case report
This report would further improve the screening of wildlife health. (Source: Comparative Clinical Pathology)
Source: Comparative Clinical Pathology - February 2, 2016 Category: Pathology Source Type: research

The association between G-197A gene polymorphism of IL-17A with changes in protein interaction of IL-17A, levels of urinary IL-17, and degree of lupus nephritis abnormality
In conclusion, the levels of uIL-17 in LN patients were significantly higher than those in the control group, but G-197A gene polymorphism of IL-17A did not cause varying levels of IL-17 and did not influence the degree of renal abnormalities in LN. (Source: Comparative Clinical Pathology)
Source: Comparative Clinical Pathology - February 2, 2016 Category: Pathology Source Type: research

Evaluation of the changes of P1NP and CTX in synovial fluid and blood serum of dogs with experimental osteoarthritis
Abstract Osteoarthritis is a degenerative and reparative process occurring in synovial joints. In the present study, collagen type I C-telopeptide (CTX) and procollagen type I N-terminal propeptide (P1NP) were measured in blood serum and synovial fluid of four cross-breed dogs with experimental CCL rupture. These biomarkers were selected as bone turnover biomarkers. The markers were measured on days 0, 14, 28, 90, and 180 post surgery. Statistical analysis showed significant increase in P1NP in both serum and synovial fluid. The CTX showed a significant increase in serum and a non significant increase in synovial ...
Source: Comparative Clinical Pathology - January 28, 2016 Category: Pathology Source Type: research

Safety evaluation of Acalypha wilkesiana in albino rats and BHK-21 cell line
We examined the phytochemical profile, cytotoxic effects on baby hamster kidney cell line (BHK-21), and oral subacute toxicity of A. wilkesiana leaf decoction in rats. Rats were given 0, 300, 600, and 1200 mg/kg body weight of A. wilkesiana leaf extract, daily, orally for 14 days. The phytochemical profile showed the presence of flavonoids, saponin, cardiac glycosides, and tannins. It caused apoptosis in BHK-21 cell line at concentrations of 0, 25, 50, 100, and 200 μg/ml. There was significant increase in the levels of serum AST, ALT, creatinine, urea, Na+, K+, and Cl− levels in all the test groups ...
Source: Comparative Clinical Pathology - January 26, 2016 Category: Pathology Source Type: research

Expression of oestrogen receptor α in the endometrium of porcine reproductive and respiratory syndrome virus-infected gilts
Abstract Porcine reproductive and respiratory syndrome (PRRS) virus infection often lead to infertility in gilts and sows. Nevertheless, the impact of PRRS virus on the endometrial function has not been fully elucidated. The present study aimed to determine the effect of PRRS virus infection on the expression of oestrogen receptor (ER) α in the endometrium of gilts. Uterine tissues from 54 gilts were classified into two groups according to PRRS virus detection using immunohistochemistry (26 positive and 28 negative samples). The reproductive status was classified as prepubertal, luteal and follicular phases....
Source: Comparative Clinical Pathology - January 25, 2016 Category: Pathology Source Type: research

Evaluation of selected biochemical parameters and hepatic enzymes activity in serum of cattle naturally infected with Dicrocoelium dendriticum in Semnan Province, Iran
Abstract The present study was conducted to investigate the effect of Dicrocoelium dendriticum on some biochemical parameters and hepatic enzymes activity in serum of cattle during the subclinical phase (asymptomatic) of the disease. Blood samples and liver of 33 indigenous cattle of Mazandarani breed, slaughtered in the period from September to November 2013, were collected. Based on parasitological findings in the liver, all animals were divided into two groups: control (n = 16) and infected group (n = 17). Biochemical analysis of tested parameters showed a significant elevation (P&th...
Source: Comparative Clinical Pathology - January 21, 2016 Category: Pathology Source Type: research

Impact of cellular CD71 (transferrin receptor 1) expression in Egyptian acute leukemia: correlation with clinicopathologic features
In conclusion, CD71 is overexpressed in acute leukemia; it predicts adverse clinical outcome in ALL. In addition, CD71 antagonism could be a possible therapeutic target in acute leukemia. (Source: Comparative Clinical Pathology)
Source: Comparative Clinical Pathology - January 20, 2016 Category: Pathology Source Type: research

Therapeutic management of epistaxis due to ehrlichiosis in a dog
Abstract A Labrador bitch was diagnosed that it was suffering with clinical ehrlichiosis. Dog exhibited epistaxis, tachycardia and hyperpnoea. Dog showed signs of anaemia, increased alanine transaminase and aspartate transaminase levels. Present case was successfully treated with oxytetracycline and doxycycline along with supportive therapy. (Source: Comparative Clinical Pathology)
Source: Comparative Clinical Pathology - January 20, 2016 Category: Pathology Source Type: research

Antibodies against Toxoplasma gondii in bats ( Desmodus rotundus ) captured near caves in cities from western region of Santa Catarina State, Brazil
This study aimed to investigate the presence of antibodies against T. gondii in the serum of 50 vampire bats (Desmodus rotundus) from the western region of Santa Catarina State, Brazil, using the modified agglutination test (MAT), in a dilution of 1:25. The results showed 10 % (5/50) are seropositive for T. gondii, showing that bats from that region had contact with T. gondii and are probably infected. (Source: Comparative Clinical Pathology)
Source: Comparative Clinical Pathology - January 15, 2016 Category: Pathology Source Type: research

The seasonal occurrence of Well’s syndrome
Abstract Well’s syndrome, in many circumstances, is determined by intensive eosinophilic infiltration into dermal layer with the clinical presentation of erythematous and edematous plaques which can easily be remitted by current corticosteroid therapies. Up to now, different etiologies have been proposed governing Well’s pathophysiological procedure. Of note, no evidence of seasonal association has been already reported. A 70-years-old afebrile male presented with a chief complaint of 30-years history of cutaneous manifestations along with non-ulcerated edematous, erythematous plaques and patches, and ...
Source: Comparative Clinical Pathology - January 6, 2016 Category: Pathology Source Type: research

Recurrent Malassezia dermatitis due to hypothyroidism in a dog and its management
Abstract Malassezia pachydermatis is the most common causative organism for development of Malassezia dermatitis in dogs. An adult pug was presented to the clinic with chronic skin abnormalities, rancid odour from the body and pruritus. Lesion distribution was noticed on the ventral chin, neck, abdomen and inner surface of the legs. Skin scrapings, hair plucks and tape impression smears were examined, and footprint-shaped Malassezia organisms were identified in impression smears. Blood was collected to diagnose underlying factor for development of chronic recurrent Malassezia dermatitis. Up on blood...
Source: Comparative Clinical Pathology - December 28, 2015 Category: Pathology Source Type: research

Vacuolar myopathic lesion in a Holstein-Friesian dairy cow affected with bovine dilated cardiomyopathy: a preliminary report
Abstract Occurrence of vacuolar myopathy caused by factors other than inherited glycogen storage condition is uncommon in domestic animals. This preliminary report describes the detection of a vacuolar myopathic lesion in a 13-year-old Holstein- Friesian dairy cow which showed an 8-day history of cardiac disease. Gross inspection after slaughter revealed edema in a variety of tissues, dilatation and hypertrophy of the cardiac ventricles, and hepatic congestion. Histopathology revealed degenerative myocardial lesions and passive hepatic congestion, which were identical to those previously documented in cases of bov...
Source: Comparative Clinical Pathology - December 22, 2015 Category: Pathology Source Type: research

Trypanosoma vivax infection in goat in west of Santa Catarina state, Brazil
Abstract The aim of this study was to report the Trypanosoma vivax in goats from a property located in the west of the state of Santa Catarina, Brazil. The identification of the parasite occurred at random, that is, it was displayed a similar morphological trypomastigote form in the blood smear of an animal in the property. Subsequently, in blood samples collected from five goats on the same day, it was confirmed by polymerase chain reaction (PCR) the presence of the parasite in three of these animals. Being that by chance, consistent clinical signs related to trypanosomosis in these animals were not observed. The...
Source: Comparative Clinical Pathology - December 21, 2015 Category: Pathology Source Type: research

Clinical evaluation of the effects of supplementation with curcuminoids on serum fetuin-B concentrations in obese subjects
Abstract Fetuin-B is an emerging negative acute phase protein, and its expression is inversely associated with inflammation. The present study aimed to assess the impact of supplementation with curcuminoids, as naturally occurring polyphenols with anti-inflammatory properties, on circulating concentrations of fetuin-B. In this randomized double-blind trial, 30 obese dyslipidemic subjects received curcuminoids (1 g/day) and matching placebo. The trial had a 2 × 2 crossover design, in which treatment duration with either of the allocations was 4 weeks, intermitted by a 2-week washout pe...
Source: Comparative Clinical Pathology - December 21, 2015 Category: Pathology Source Type: research

Haematological and serum biochemical reference values for captive blue-fronted amazon parrot
This study aimed to determine haematology and biochemistry reference values for A. aestiva to assist veterinarian and conservation programmes in the care of this species. Sampling was conducted in April 2014; a total of 32 birds were manually restrained, and their blood samples were collected and divided into two aliquots. Haematological parameters evaluated included red blood cell (RBC) count, white blood cell (WBC) count, differential leukocyte count, haematocrit, thrombocyte count, haemoglobin concentration and RBC indexes. The biochemical parameters measured were alkaline phosphatase, alanine aminotransferase, gamma gl...
Source: Comparative Clinical Pathology - December 18, 2015 Category: Pathology Source Type: research

A mini review of histological and genetic oral lesions in adult and elderly patients referred to Shiraz Dentistry School
This article is a mini review of some common oral lesions especially in adults and elderly patients who attended Shiraz Dentistry School, Iran, and is designed to help all dental practitioners to be more ready to deal with these lesions. (Source: Comparative Clinical Pathology)
Source: Comparative Clinical Pathology - December 15, 2015 Category: Pathology Source Type: research

Novel data for free-living saffron finch ( Sicalis flaveola ): reference hematological value and body mass
Abstract The Sicalis flaveola specie is also known as saffron finch. It is known to be in the illegally traded and mostly to be used as pets. Although the saffron finch is not listed as threatened species, the hunting, destruction of habit, and introduction of hybrid and exotic specimens to the natural environment can put the specie in risk, and they have been already cited in some regions to be found rarely. Due to the lack of hematological data for the specie S. flaveola, this study aimed to describe the hematological reference values and biometric data (weight) for the specie. Thirty-eight saffron finches where...
Source: Comparative Clinical Pathology - December 14, 2015 Category: Pathology Source Type: research

Hematological reference values of healthy adult Sangsari sheep (Iranian fat-tailed sheep) estimated by Reference Value Advisor
In this study, we used a total 63 healthy Sangsari sheep at the same physiological status for both sex with two ages (2–4 years) from June to July 2014. Hematological parameters were measured by routine methods, and finally, reference interval (RI) was determined by the robust method and Box-Cox transformation (Reference Value Advisor). The RI of hematological parameters obtained in this study includes the following: hematocrit (Hct) 14.3–35.3 %; Hb 5.4–12.52 gr/dl; mean corpuscular volume (MCV) 26.2–36.3 fl; mean corpuscular hemoglobin (MCH) 8.6–12.3 pg; mean corpuscu...
Source: Comparative Clinical Pathology - December 11, 2015 Category: Pathology Source Type: research

Alternative feedstuffs and their effects on blood chemistry and haematology of rabbits and chickens: a review
Abstract The demand for meat in developing countries is on the increase, and this trend is expected to continue over the years. The ability of poultry and rabbit to meet the animal protein demand in developing countries cannot be overemphasized. However, the main constraint limiting effective and efficient use of these choice animals is the high cost of traditional feed ingredients such as maize, soybean meal, fish meal and groundnut cake which are in strict competition with man’s dietary need. However, it is also becoming clear that the requirements for the traditional feed ingredients cannot be met, even a...
Source: Comparative Clinical Pathology - December 8, 2015 Category: Pathology Source Type: research

Horner’s syndrome and unilateral facial paresis in a goat: a case report
Abstract A 4-year-old, female Pakistani goat was referred to the veterinary teaching hospital for first pregnancy check up. At the time of presentation, the case was apparently healthy. Incidentally, the clinicians noticed the abnormality in the left eye. A precise ophthalmic examination revealed ptosis, entropion, nictitating membrane prolapse, enophthalmos, and miosis in the left eye, whereas the eyelids and pupil were normal on the right side. The left eye lacked palpebral reflex, and the menace response seemed to be decreased. Pupillary light reflex was present in both eyes. The eyes did not show any evidence ...
Source: Comparative Clinical Pathology - December 7, 2015 Category: Pathology Source Type: research