Nivolumab combined with brentuximab vedotin with or without mediastinal radiotherapy for relapsed/refractory primary mediastinal large B-cell lymphoma
Haematologica. 2024 May 2. doi: 10.3324/haematol.2023.284689. Online ahead of print.ABSTRACTNot available.PMID:38695142 | DOI:10.3324/haematol.2023.284689 (Source: Haematologica)
Source: Haematologica - May 2, 2024 Category: Hematology Authors: Loic Renaud Juliette Wencel Arnaud Pag ès Ahmad Al Jijakli Hannah Moatti Laurent Quero Vincent Camus Pauline Brice Source Type: research

Outcomes and genetic dynamics of acute myeloid leukemia at first relapse
Haematologica. 2024 May 2. doi: 10.3324/haematol.2024.285057. Online ahead of print.ABSTRACTPatients with relapsed acute myeloid leukemia (rAML) experience dismal outcomes. We performed a comprehensive analysis of patients with rAML to determine the genetic dynamics and survival predictive factors. We analyzed 875 patients with newly diagnosed AML who received intensive treatment (IT) or low-intensity treatment (LIT). Of these patients, 197 experienced subsequent rAML. Data was available for 164 patients, with a median time from CR/CRi to relapse of 6.5 months. Thirty-five of the 164 patients (21%) experienced relapse afte...
Source: Haematologica - May 2, 2024 Category: Hematology Authors: Alex Bataller Hagop Kantarjian Alexandre Bazinet Tapan Kadia Naval Daver Courtney D DiNardo Gautam Borthakur Sanam Loghavi Keyur Patel Guilin Tang Koji Sasaki Nicholas J Short Musa Yilmaz Ghayas C Issa Yesid Alvarado Guillermo Montalban-Bravo Abhishek Mai Source Type: research

New bullets in the fight against cancer
Haematologica. 2024 May 1;109(5):1313-1314. doi: 10.3324/haematol.2024.285334.NO ABSTRACTPMID:38695267 | PMC:PMC11063851 | DOI:10.3324/haematol.2024.285334 (Source: Haematologica)
Source: Haematologica - May 2, 2024 Category: Hematology Authors: Ofir Wolach Source Type: research

Stable measurement of chemistry, immunochemistry, and hematology analytes in a heparin-based anticoagulant with iloprost additive: A promising candidate for the polyvalent blood collection tube
CONCLUSIONS: Our novel dry-sprayed anticoagulant formulation, HEP-ILOP, is a promising candidate for a polyvalent blood collection tube, enabling the analysis of hematology, chemistry, and immunochemistry analytes in the same tube.PMID:38695255 | DOI:10.1111/ijlh.14291 (Source: International Journal of Laboratory Hematology)
Source: International Journal of Laboratory Hematology - May 2, 2024 Category: Hematology Authors: Elias Frost Wiwe Laura Emilie Schmidt Emilie Zeuthen Ida Maria Storm Engelstoft Buris Brinch Christiansen Thomas Steen Hansen Melanie A Burkhardt Claus Antonio Juel Jensen Source Type: research

Erythrocytosis: Diagnosis and investigation
Int J Lab Hematol. 2024 May 2. doi: 10.1111/ijlh.14298. Online ahead of print.ABSTRACTAn absolute erythrocytosis is present when the red cell mass is greater than 125% of the predicted. This is suspected when the hemoglobin or hematocrit is above the normal range. An erythrocytosis can be classified as primary or secondary and congenital or acquired. The commonest primary acquired disorder is polycythemia vera. The diagnostic criteria for PV have evolved over time and this is the main diagnosis managed in hematology clinics. There are a variety of rare congenital causes both primary and secondary. In particular in young pa...
Source: International Journal of Laboratory Hematology - May 2, 2024 Category: Hematology Authors: Iman Noumani Claire N Harrison Mary Frances McMullin Source Type: research

Are we closer to a standard of care for Richter's syndrome? Novel treatments on the horizon
Expert Rev Hematol. 2024 May 1. doi: 10.1080/17474086.2024.2350528. Online ahead of print.ABSTRACTINTRODUCTION: The therapeutic landscape for chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) has significantly evolved over the past decade with dramatically improved outcomes with the introduction of targeted therapies. This unfortunately has not been the case for Richter transformation (RT), the histologic transformation to a more aggressive lymphoma, most typically diffuse large B-cell lymphoma (DLBCL). As such, RT continues to be one of the most challenging complications of CLL/SLL. Historically, RT has a ...
Source: Expert Review of Hematology - May 2, 2024 Category: Hematology Authors: Nghia Pham Catherine C Coombs Susan O'Brien Source Type: research

Health-care-seeking behaviour in patients with hypertension: experience from a dedicated hypertension centre in Bangladesh
Conclusions: Raising awareness among patients and proper referral to specialised hypertension centres could promulgate the patients towards appropriate behaviour.PMID:38696746 | DOI:10.1080/08037051.2024.2339434 (Source: Blood Pressure)
Source: Blood Pressure - May 2, 2024 Category: Hematology Authors: Mohammad Jahid Hasan Md Zakir Hossain Md Anwar Hossain Koustuv Dalal Md Abdul Baset Probal Sutradhar Mahabubul Alam Tamanna Tabassum Jannatul Fardous Paramita Zaman Md Abdur Rafi Md Abdullah Saeed Khan Mohammad Delwer Hossain Hawlader Source Type: research

Ocimum gratissimum essential oil in the transport water of Brycon hilarii: implications at water quality, blood parameters and residues in tissue and plasma
This study aimed to assess the impact of Ocimum gratissimum L. essential oil (OGEO) on water quality, hematological parameters, and residue levels in the plasma, fillet, and liver of juvenile piraputanga (Brycon hilarii) during a two-hour transportation period. The fish were divided into plastic bags (4 L) and exposed to three different OGEO concentrations (10, 20, and 30 mg L-1), while a control group received no OGEO (three repetitions each). After the two-hour transportation, blood samples were collected, as well as portions of the fillet and liver for quantifying essential oil compounds, which were also measured in the...
Source: Braz J Biol - May 2, 2024 Category: Biology Authors: F C Oliveira A P Moreira A L Ferreira D C Costa C A L Cardoso F C M Chaves E C Chagas C M Campos Source Type: research

Very unusual extremely high ferritin with cytokine release syndrome in a patient with hematological malignancy after experimental chimeric antigen receptor (CAR)-T-Cell therapy
CONCLUSIONS: Cytokine release syndrome after experimental (CAR) T cell therapy may cause extremely elevated ferritin and hemophagocytic lymphohistiocytosis -like syndrome.PMID:38697457 | DOI:10.1016/j.cca.2024.119704 (Source: International Journal of Clinical Chemistry)
Source: International Journal of Clinical Chemistry - May 2, 2024 Category: Chemistry Authors: Robert Hoyt Zhan Ye Amitava Dasgupta Source Type: research

Anemia and Associated Factors among Public Elementary School Children in Asella Town, Southeast Ethiopia: A Facility-Based Cross-Sectional Study
CONCLUSION: Anemia among school-age children was found to be a mild public health problem. Uneducated mothers, intestinal parasite infections, and underweight children were found to be determinants of anemia among school-age children. Health professionals should provide health education for mothers about child-feeding practices and the consumption of dietary sources of iron.PMID:38694783 | PMC:PMC11062769 | DOI:10.1155/2024/1519382 (Source: Anemia)
Source: Anemia - May 2, 2024 Category: Hematology Authors: Ararso Hordofa Guye Kasim Hansa Kasahun Ketema Meseret Moroda Dame Banti Shambi Source Type: research

Incidence rate of venous thrombosis in women switching combined oral contraceptives: a cohort study
CONCLUSION: Switchers, particularly in the first 3 months after switching, may experience a renewed starter effect thereby increasing the risk of VT.PMID:38694836 | PMC:PMC11060944 | DOI:10.1016/j.rpth.2024.102390 (Source: Thrombosis and Haemostasis)
Source: Thrombosis and Haemostasis - May 2, 2024 Category: Hematology Authors: Deeksha Khialani Esther de Rooij Szimonetta Komj áthiné Szépligeti Elena Dudukina Saskia le Cessie Vera Ehrenstein Frits R Rosendaal Astrid van Hylckama Vlieg Source Type: research

Anticoagulation and vascular anomalies
Res Pract Thromb Haemost. 2024 Apr 3;8(3):102402. doi: 10.1016/j.rpth.2024.102402. eCollection 2024 Mar.ABSTRACTA State of the Art lecture titled "Anticoagulation and Vascular Anomalies" was presented at the International Society on Thrombosis and Haemostasis (ISTH) Congress in 2023. Vascular anomalies have been classified by the International Society for the Study of Vascular Anomalies into vascular tumors and vascular malformations. Although some vascular tumors, such as tufted angioma and kaposiform hemangioendothelioma, and other vascular malformations can present with coagulation aberrancies, these are not generally m...
Source: Thrombosis and Haemostasis - May 2, 2024 Category: Hematology Authors: Shelley E Crary Joana M Mack Source Type: research

Patient counseling for pulmonary embolism requires an individualized approach
Res Pract Thromb Haemost. 2024 Apr 12;8(3):102407. doi: 10.1016/j.rpth.2024.102407. eCollection 2024 Mar.NO ABSTRACTPMID:38694838 | PMC:PMC11060943 | DOI:10.1016/j.rpth.2024.102407 (Source: Thrombosis and Haemostasis)
Source: Thrombosis and Haemostasis - May 2, 2024 Category: Hematology Authors: Carolyn G Chatterton Lina A Fouad Jeffrey A Kline Source Type: research

Plantar vein thrombosis: 17-year longitudinal study of consecutive patients from a Swiss academic center
CONCLUSION: We provided initial information on the clinical characteristics, treatment, and course of PVT, which partly resembles that of distal deep vein thrombosis.PMID:38694839 | PMC:PMC11061322 | DOI:10.1016/j.rpth.2024.102396 (Source: Thrombosis and Haemostasis)
Source: Thrombosis and Haemostasis - May 2, 2024 Category: Hematology Authors: Margarita Serifi Philippe A Kaufmann Riccardo M Fumagalli Adrian Kobe Nils Kucher Stefano Barco Source Type: research

New bullets in the fight against cancer
Haematologica. 2024 May 1;109(5):1313-1314. doi: 10.3324/haematol.2024.285334.NO ABSTRACTPMID:38695267 | DOI:10.3324/haematol.2024.285334 (Source: Haematologica)
Source: Haematologica - May 2, 2024 Category: Hematology Authors: Ofir Wolach Source Type: research