Very unusual extremely high ferritin with cytokine release syndrome in a patient with hematological malignancy after experimental chimeric antigen receptor (CAR)-T-Cell therapy
CONCLUSIONS: Cytokine release syndrome after experimental (CAR) T cell therapy may cause extremely elevated ferritin and hemophagocytic lymphohistiocytosis -like syndrome.PMID:38697457 | DOI:10.1016/j.cca.2024.119704 (Source: International Journal of Clinical Chemistry)
Source: International Journal of Clinical Chemistry - May 2, 2024 Category: Chemistry Authors: Robert Hoyt Zhan Ye Amitava Dasgupta Source Type: research

Anemia and Associated Factors among Public Elementary School Children in Asella Town, Southeast Ethiopia: A Facility-Based Cross-Sectional Study
CONCLUSION: Anemia among school-age children was found to be a mild public health problem. Uneducated mothers, intestinal parasite infections, and underweight children were found to be determinants of anemia among school-age children. Health professionals should provide health education for mothers about child-feeding practices and the consumption of dietary sources of iron.PMID:38694783 | PMC:PMC11062769 | DOI:10.1155/2024/1519382 (Source: Anemia)
Source: Anemia - May 2, 2024 Category: Hematology Authors: Ararso Hordofa Guye Kasim Hansa Kasahun Ketema Meseret Moroda Dame Banti Shambi Source Type: research

Incidence rate of venous thrombosis in women switching combined oral contraceptives: a cohort study
CONCLUSION: Switchers, particularly in the first 3 months after switching, may experience a renewed starter effect thereby increasing the risk of VT.PMID:38694836 | PMC:PMC11060944 | DOI:10.1016/j.rpth.2024.102390 (Source: Thrombosis and Haemostasis)
Source: Thrombosis and Haemostasis - May 2, 2024 Category: Hematology Authors: Deeksha Khialani Esther de Rooij Szimonetta Komj áthiné Szépligeti Elena Dudukina Saskia le Cessie Vera Ehrenstein Frits R Rosendaal Astrid van Hylckama Vlieg Source Type: research

Anticoagulation and vascular anomalies
Res Pract Thromb Haemost. 2024 Apr 3;8(3):102402. doi: 10.1016/j.rpth.2024.102402. eCollection 2024 Mar.ABSTRACTA State of the Art lecture titled "Anticoagulation and Vascular Anomalies" was presented at the International Society on Thrombosis and Haemostasis (ISTH) Congress in 2023. Vascular anomalies have been classified by the International Society for the Study of Vascular Anomalies into vascular tumors and vascular malformations. Although some vascular tumors, such as tufted angioma and kaposiform hemangioendothelioma, and other vascular malformations can present with coagulation aberrancies, these are not generally m...
Source: Thrombosis and Haemostasis - May 2, 2024 Category: Hematology Authors: Shelley E Crary Joana M Mack Source Type: research

Patient counseling for pulmonary embolism requires an individualized approach
Res Pract Thromb Haemost. 2024 Apr 12;8(3):102407. doi: 10.1016/j.rpth.2024.102407. eCollection 2024 Mar.NO ABSTRACTPMID:38694838 | PMC:PMC11060943 | DOI:10.1016/j.rpth.2024.102407 (Source: Thrombosis and Haemostasis)
Source: Thrombosis and Haemostasis - May 2, 2024 Category: Hematology Authors: Carolyn G Chatterton Lina A Fouad Jeffrey A Kline Source Type: research

Plantar vein thrombosis: 17-year longitudinal study of consecutive patients from a Swiss academic center
CONCLUSION: We provided initial information on the clinical characteristics, treatment, and course of PVT, which partly resembles that of distal deep vein thrombosis.PMID:38694839 | PMC:PMC11061322 | DOI:10.1016/j.rpth.2024.102396 (Source: Thrombosis and Haemostasis)
Source: Thrombosis and Haemostasis - May 2, 2024 Category: Hematology Authors: Margarita Serifi Philippe A Kaufmann Riccardo M Fumagalli Adrian Kobe Nils Kucher Stefano Barco Source Type: research

New bullets in the fight against cancer
Haematologica. 2024 May 1;109(5):1313-1314. doi: 10.3324/haematol.2024.285334.NO ABSTRACTPMID:38695267 | DOI:10.3324/haematol.2024.285334 (Source: Haematologica)
Source: Haematologica - May 2, 2024 Category: Hematology Authors: Ofir Wolach Source Type: research

Are we ready for new strategies to prevent stroke in children with sickle cell disease?
Haematologica. 2024 May 2. doi: 10.3324/haematol.2024.285328. Online ahead of print.ABSTRACTNot available.PMID:38695140 | DOI:10.3324/haematol.2024.285328 (Source: Haematologica)
Source: Haematologica - May 2, 2024 Category: Hematology Authors: Giovanna Russo Raffaella Colombatti Source Type: research

Nivolumab combined with brentuximab vedotin with or without mediastinal radiotherapy for relapsed/refractory primary mediastinal large B-cell lymphoma
Haematologica. 2024 May 2. doi: 10.3324/haematol.2023.284689. Online ahead of print.ABSTRACTNot available.PMID:38695142 | DOI:10.3324/haematol.2023.284689 (Source: Haematologica)
Source: Haematologica - May 2, 2024 Category: Hematology Authors: Loic Renaud Juliette Wencel Arnaud Pag ès Ahmad Al Jijakli Hannah Moatti Laurent Quero Vincent Camus Pauline Brice Source Type: research

Outcomes and genetic dynamics of acute myeloid leukemia at first relapse
Haematologica. 2024 May 2. doi: 10.3324/haematol.2024.285057. Online ahead of print.ABSTRACTPatients with relapsed acute myeloid leukemia (rAML) experience dismal outcomes. We performed a comprehensive analysis of patients with rAML to determine the genetic dynamics and survival predictive factors. We analyzed 875 patients with newly diagnosed AML who received intensive treatment (IT) or low-intensity treatment (LIT). Of these patients, 197 experienced subsequent rAML. Data was available for 164 patients, with a median time from CR/CRi to relapse of 6.5 months. Thirty-five of the 164 patients (21%) experienced relapse afte...
Source: Haematologica - May 2, 2024 Category: Hematology Authors: Alex Bataller Hagop Kantarjian Alexandre Bazinet Tapan Kadia Naval Daver Courtney D DiNardo Gautam Borthakur Sanam Loghavi Keyur Patel Guilin Tang Koji Sasaki Nicholas J Short Musa Yilmaz Ghayas C Issa Yesid Alvarado Guillermo Montalban-Bravo Abhishek Mai Source Type: research

CD22-targeted glyco-engineered natural killer cells offer a further treatment option for B-cell acute lymphoblastic leukemia
Haematologica. 2024 May 2. doi: 10.3324/haematol.2023.284241. Online ahead of print.ABSTRACTNot available.PMID:38695137 | DOI:10.3324/haematol.2023.284241 (Source: Haematologica)
Source: Haematologica - May 2, 2024 Category: Hematology Authors: Xin Jin Rui Sun Zhu Li Xianwu Wang Xia Xiong Wenyi Lu Hairong Lyu Xia Xiao Yunpeng Tian Hongkai Zhang Zhihong Fang Luqiao Wang Mingfeng Zhao Source Type: research

Minimal residual disease monitoring in childhood Philadelphia-positive acute lymphoblastic leukemia: prognostic significance and correlation between multiparameter flow cytometry and real-time quantitative polymerase chain reaction
Haematologica. 2024 May 2. doi: 10.3324/haematol.2024.285119. Online ahead of print.ABSTRACTNot available.PMID:38695139 | DOI:10.3324/haematol.2024.285119 (Source: Haematologica)
Source: Haematologica - May 2, 2024 Category: Hematology Authors: Jun Li Anni Lu Yangyang Gao Yang Wan Junxia Wang Jingliao Zhang Tianyuan Hu Peng Wu Xiaojuan Chen Yao Zou Yumei Chen Li Zhang Ye Guo Wenyu Yang Chengwen Li Yingchi Zhang Xiaofan Zhu Source Type: research

Two-sample Mendelian randomization analysis reveals causal relationships between blood lipids and venous thromboembolism
Haematologica. 2024 May 2. doi: 10.3324/haematol.2023.284566. Online ahead of print.ABSTRACTVenous Thromboembolism (VTE) is a complex disease that can be classified into two subtypes: Deep Vein Thrombosis (DVT) and Pulmonary Embolism (PE). Previous observational studies have shown associations between lipids and VTE, but causality remains unclear. Hence, by utilizing 241 lipid-related traits as exposures and data from the FinnGen consortium on VTE, DVT, and PE as outcomes, we conducted two-sample Mendelian randomization (MR) analysis to investigate causal relationships between lipids and VTE, DVT and PE. The MR results ide...
Source: Haematologica - May 2, 2024 Category: Hematology Authors: Wei Huang Yan Zou Kun Zhang Shi Yao Shi-Hao Tang Hao Wu Peng-Fei Wang Han-Zhong Xue Tie-Lin Yang Kun Zhang Yan Guo Source Type: research

Soluble urokinase plasminogen activator receptor is associated with kidney disease and its progression in sickle cell anemia
Haematologica. 2024 May 2. doi: 10.3324/haematol.2023.284920. Online ahead of print.ABSTRACTNot available.PMID:38695132 | DOI:10.3324/haematol.2023.284920 (Source: Haematologica)
Source: Haematologica - May 2, 2024 Category: Hematology Authors: Rima S Zahr Sara R Rashkin Maria Armila Ruiz Laila Elsherif Guohui Ren Guadalupe Salas Kenneth I Ataga Victor R Gordeuk Jeffrey Lebensburger Xu Zhang Santosh L Saraf Source Type: research

The initial molecular response predicts the deep molecular response but not treatment-free remission maintenance in a real-world chronic myeloid leukemia cohort
In conclusion, this first comparative study of early therapeutic response parameters showed that they are excellent indicators of TKI efficacy (BCR::ABL1 transcript reduction) and best responders. Conversely, they did not predict the achievement of the TKI discontinuation criteria and TFR maintenance, suggesting that other parameters are involved in TFR maintenance.PMID:38695126 | DOI:10.3324/haematol.2023.284860 (Source: Haematologica)
Source: Haematologica - May 2, 2024 Category: Hematology Authors: Sandrine Saugues C éline Lambert Elisabeth Daguenet Gabrielle Roth-Guepin Fran çoise Huguet Pascale Cony-Makhoul Hyacinthe Johnson Ansah Martine Escoffre-Barbe Ali Turhan Philippe Rousselot Andre ï Tchirkov Dalil Hamroun Eric Hermet Bruno Pereira Marc Source Type: research