International Journal of Clinical Chemistry This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Targeted plasma proteomic analysis uncovers a high-performance biomarker panel for early diagnosis of gastric cancer
CONCLUSIONS: This study identified a multi-protein signature with the potential to benefit clinical GC diagnosis, especially for Asian and early GC patients, which may contribute to the development of a less-invasive, convenient, and efficient early screening tool, promoting early diagnosis and treatment of GC and ultimately improving patient survival.PMID:38631604 | DOI:10.1016/j.cca.2024.119675 (Source: International Journal of Clinical Chemistry)
Source: International Journal of Clinical Chemistry - April 17, 2024 Category: Chemistry Authors: Tong Feng Minwen Jie Kai Deng Jinlin Yang Hao Jiang Source Type: research

Reflex strategy to ensure accurate total testosterone results from consumer initiated, self-collected capillary samples
CONCLUSION: Self-collected capillary specimens are acceptable for TT testing. A quality assurance reflex to LH/FSH can determine the validity of supraphysiological TT results in a consumer initiated/DAT population.PMID:38631605 | DOI:10.1016/j.cca.2024.119676 (Source: International Journal of Clinical Chemistry)
Source: International Journal of Clinical Chemistry - April 17, 2024 Category: Chemistry Authors: Anissa R Naranjo Matthew D Krasowski Amal Hamdan Kristin O'Connor Claire Carter Joyce Chen Dina N Greene Source Type: research

C. difficile biomarkers, pathogenicity and detection
CONCLUSION: To overcome the deficiencies of conventional methods, the potential of advanced methods for C. difficile diagnosis, their direction, perspective, and challenges ahead were discussed.PMID:38621586 | DOI:10.1016/j.cca.2024.119674 (Source: International Journal of Clinical Chemistry)
Source: International Journal of Clinical Chemistry - April 15, 2024 Category: Chemistry Authors: Sepideh Ziaei Chamgordani Abbas Yadegar Hedayatollah Ghourchian Source Type: research

A machine learning algorithm based on circulating metabolic biomarkers offers improved predictions of neurological diseases
CONCLUSION: The performance of the model based on circulating NMR spectroscopy-detected metabolic biomarkers was better than that of the clinical model in the prediction of dementia, AD, and PD.PMID:38621587 | DOI:10.1016/j.cca.2024.119671 (Source: International Journal of Clinical Chemistry)
Source: International Journal of Clinical Chemistry - April 15, 2024 Category: Chemistry Authors: Liyuan Han Xi Chen Wang Yue Ruijie Zhang Tian Zhao Liyuan Pu Yi Huang Hongpeng Sun Source Type: research

Space research to explore novel biochemical insights on Earth
Clin Chim Acta. 2024 Apr 15;558:119673. doi: 10.1016/j.cca.2024.119673. Online ahead of print.ABSTRACTTravel to space has overcome unprecedent technological challenges and this has resulted in transfer of these technological results on Earth to better our lives. Health technology, medical devices, and research advancements in human biology are the first beneficiaries of this transfer. The real breakthrough came with the International Space Station, which endorsed multidisciplinary international scientific collaborations and boosted the research on pathophysiological adaptation of astronauts to life on space. These studies ...
Source: International Journal of Clinical Chemistry - April 15, 2024 Category: Chemistry Authors: Simona Ferraro Anilkumar Dave Cristina Cereda Elvira Verduci Santica Marcovina Gianvincenzo Zuccotti Source Type: research

Reference interval establishment and correlation research of urine thromboxane metabolites: Unveiling new possibilities in platelet activation
CONCLUSION: The establishment of RI provides a reference for diseases related to platelet activation and the use of drugs, and the first discovery of the correlation between 11dhTxB2 and 11dh23dinorTxB2 in urine provides a new possibilitie for the diagnostic and prognostic of cardiovascular diseases.PMID:38621589 | DOI:10.1016/j.cca.2024.119672 (Source: International Journal of Clinical Chemistry)
Source: International Journal of Clinical Chemistry - April 15, 2024 Category: Chemistry Authors: Yunfeng Cao Furong Zhao Shuang Wang Ying Li Shuainan Li Xueting Cui Source Type: research

Space research to explore novel biochemical insights on Earth
Clin Chim Acta. 2024 Apr 13:119673. doi: 10.1016/j.cca.2024.119673. Online ahead of print.ABSTRACTTravel to space has overcome unprecedent technological challenges and this has resulted in transfer of these technological results on Earth to better our lives. Health technology, medical devices, and research advancements in human biology are the first beneficiaries of this transfer. The real breakthrough came with the International Space Station, which endorsed multidisciplinary international scientific collaborations and boosted the research on pathophysiological adaptation of astronauts to life on space. These studies evid...
Source: International Journal of Clinical Chemistry - April 15, 2024 Category: Chemistry Authors: Simona Ferraro Anilkumar Dave Cristina Cereda Elvira Verduci Santica Marcovina Gianvincenzo Zuccotti Source Type: research

Cancer risk and male Infertility: Unravelling predictive biomarkers and prognostic indicators
Clin Chim Acta. 2024 Apr 11:119670. doi: 10.1016/j.cca.2024.119670. Online ahead of print.ABSTRACTIn recent years, there has been a global increase in cases of male infertility. There are about 30 million cases of male infertility worldwide and male reproductive health is showing rapid decline in last few decades. It is now recognized as a potential risk factor for developing certain types of cancer, particularly genitourinary malignancies like testicular and prostate cancer. Male infertility is considered a potential indicator of overall health and an early biomarker for cancer. Cases of unexplained male factor infertilit...
Source: International Journal of Clinical Chemistry - April 13, 2024 Category: Chemistry Authors: Prabhakar Tiwari Anjali Yadav Meenakshi Kaushik Rima Dada Source Type: research