Correlations between Iron Load and CD4 in Adult Transfusion-Dependent Beta Thalassemia
CONCLUSION: There were no correlations between iron overload (ferritin) and cellular immunity (CD4) in adult transfusion-dependent thalassemia.PMID:34239727 | PMC:PMC8233081 | DOI:10.1155/2021/5549503 (Source: Anemia)
Source: Anemia - July 9, 2021 Category: Hematology Authors: Tubagus Djumhana Atmakusuma Ralph Girson Sukamto Koesnoe Source Type: research

Human Acquired Aplastic Anemia Patients' Bone-Marrow-Derived Mesenchymal Stem Cells Are Not Influenced by Hematopoietic Compartment and Maintain Stemness and Immune Properties
CONCLUSION: Our results confirm that the basic and immunosuppressive properties of BM-MSCs from aAA patients do not differ from normal BM-MSCs. Our data suggest that BM-MSCs from aAA patients might not be involved in disease pathogenesis. However, owing to a smaller number of samples, it is not conclusive, and future studies with more exhaustive investigation at transcriptome level are warranted.PMID:34012684 | PMC:PMC8105116 | DOI:10.1155/2021/6678067 (Source: Anemia)
Source: Anemia - May 20, 2021 Category: Hematology Authors: Vandana Sharma Sonali Rawat Suchi Gupta Sweta Tamta Rinkey Sharma Tulika Seth Sujata Mohanty Source Type: research

Iron Overload in Transfusion-Dependent Indonesian Thalassemic Patients
Anemia. 2021 Apr 15;2021:5581831. doi: 10.1155/2021/5581831. eCollection 2021.ABSTRACTThalassemia is a genetic disease caused by disruption of globin chain synthesis leading to severe anemia and thus regular blood transfusion is necessary. However, there have been known transfusions-related consequences, including iron overload and multi-organ damage. The aims of this study were to evaluate liver and cardiac function in youth and adult transfusion-dependent Indonesian thalassemic patients and to assess its correlation with serum ferritin levels, as well as T2 ∗ magnetic resonance imaging (MRI). Transfusion-dependent...
Source: Anemia - May 6, 2021 Category: Hematology Authors: Pandji Irani Fianza Anita Rahmawati Sri Hudaya Widihastha Shofura Afifah Mohammad Ghozali Andre Indrajaya Dilli Marayuzan Akbar Pratama Dimmy Prasetya Teddy Arnold Sihite Mas Rizky A A Syamsunarno Djatnika Setiabudi Suthat Fucharoen Ramdan Panigoro Source Type: research