First Trimester Ferritin Is Superior over Soluble Transferrin Receptor and Hepcidin in Predicting Anemia in the Third Trimester: Result from a Cohort Study in Indonesia.
This study aimed at defining the best marker among ferritin, hepcidin, or soluble transferrin receptor (sTfR) in the first trimester for prediction of anemia in the third trimester. Materials, Methods, and Setting. This diagnostic study was nested on the cohort study of vitamin D and its impact during pregnancy in Indonesia. Singleton pregnant mothers with normal fetus were recruited in the first trimester from four cities in West Java, Indonesia. The 304 pregnant women were screened for hepcidin, ferritin, and sTfR level in the sera. All biomarkers were measured by ELISA. Complete blood count (CBC) was done by impedance m...
Source: Anemia - October 27, 2020 Category: Hematology Tags: Anemia Source Type: research

Prevalence of Anemia and Associated Factors among Secondary School Adolescent Girls in Jimma Town, Oromia Regional State, Southwest Ethiopia.
Authors: Fentie K, Wakayo T, Gizaw G Abstract Background: Anemia defined as a low blood hemoglobin concentration is public health importance. The adolescence age group is the most neglected in public health and nutrition research as priorities are usually given to pregnant women, lactating mothers, and their children less than 2 years. Current Ethiopian Food and Nutrition policy included adolescent girls in the most at-risk group for nutritional demands; however, only a few published studies have assessed a deficiency of anemia and associated factors to tackle the intergenerational cycle of malnutrition. Object...
Source: Anemia - October 10, 2020 Category: Hematology Tags: Anemia Source Type: research

Pregnancy Outcomes among Patients with Sickle Cell Disease in Brazzaville.
Conclusion: The risk of pregnancy in patients with homozygous sickle cell anemia remains high, on both the maternal and fetal sides. PMID: 33014460 [PubMed] (Source: Anemia)
Source: Anemia - October 7, 2020 Category: Hematology Tags: Anemia Source Type: research

Blood Transfusion Frequency and Indications in Yemeni Children with Sickle Cell Disease.
Conclusion: Intermittent blood transfusion remains a common practice for the management of children with acute SCD complications. Main indications were acute anemic crises, severe pain crises, ACS, and stroke. In limited resource settings, such as Yemen, conservative transfusion policy appears to be appropriate. PMID: 32908695 [PubMed] (Source: Anemia)
Source: Anemia - September 13, 2020 Category: Hematology Tags: Anemia Source Type: research

Magnitude, Severity, and Associated Factors of Anemia among Under-Five Children Attending Hawassa University Teaching and Referral Hospital, Hawassa, Southern Ethiopia, 2016.
Conclusion: The prevalence of anemia among the study subjects was 41.7% indicative of the fact that anemia is an important public health problem. It was associated with the child's age, residence, mother's education level, and intestinal parasite (Ascaris lumbricoides). It clearly indicates that there should be well integrated public health interventions to improve the health status that needs to be prioritized to prevent anemia among children under five years of age. PMID: 32832148 [PubMed - as supplied by publisher] (Source: Anemia)
Source: Anemia - August 25, 2020 Category: Hematology Tags: Anemia Source Type: research

Prevalence and Associated Factors of Anemia among Reproductive-Aged Women in Sayint Adjibar Town, Northeast Ethiopia: Community-Based Cross-Sectional Study.
Authors: Woldu B, Enawgaw B, Asrie F, Shiferaw E, Getaneh Z, Melku M Abstract Background: Globally, anemia affects one-fourth of the world population including 30% of nonpregnant reproductive-aged women. It has a number of causes including micronutrient deficiencies and chronic infections, inherited or acquired disorders of hemoglobin synthesis and red blood cell production, or survival alterations. The aim of this study was to assess the prevalence and associated factors of anemia among reproductive-aged women in Sayint Adjibar town, South Wollo Zone, Northeast Ethiopia. Methods: A community-based cross-sectio...
Source: Anemia - August 25, 2020 Category: Hematology Tags: Anemia Source Type: research

Screening for Anemia and Iron Deficiency in the Adult Portuguese Population.
In conclusion, anemia and ID represent moderate to severe public health problems, particularly among women in fertile age and in 3rd trimester, of pregnancy emphasizing the need to raise the public and health professionals' awareness of these problems and their prevention, diagnosis, and treatment. PMID: 32802501 [PubMed - as supplied by publisher] (Source: Anemia)
Source: Anemia - August 18, 2020 Category: Hematology Tags: Anemia Source Type: research

The Trabecular Bone Score as a Predictor for Thalassemia-Induced Vertebral Fractures in Northeastern Thailand.
Conclusions: The prevalence of vertebral fractures in patients with thalassemia was not uncommon. A combined low BMD and TBS and a presence of endocrinopathies were associated with vertebral fractures. These findings suggested that BMD testing and TBS measurement have a clinical implication as a screening tool for evaluating the risk of vertebral fractures in thalassemic patients, particularly in β-thalassemia/Hb E who have endocrinopathies. PMID: 32774916 [PubMed] (Source: Anemia)
Source: Anemia - August 14, 2020 Category: Hematology Tags: Anemia Source Type: research

Association between Helicobacter pylori Infection and Occurrence of Anemia among Pregnant Women Attending Antenatal Care in Kulito Health Center, Halaba Zone, South Ethiopia, 2018.
Authors: Abdella B, Ibrahim M, Tadesse I, Hassen K, Tesfa M Abstract Background: Anemia in pregnancy is defined as a hemoglobin (Hb) concentration of less than 11 grams (gm)/deciliter (dl) in venous blood. Globally, it affects 1.62 billion people. In developing countries, anemia is a major cause of maternal and child morbidity and mortality. Globally, anemia contributes to 20% of all maternal deaths. Nearly 50% of the world's population is estimated to be infected with Helicobacter pylori (HP). High prevalence of HP among pregnant women was also reported in developing countries than developed ones. The association ...
Source: Anemia - August 14, 2020 Category: Hematology Tags: Anemia Source Type: research

Proportion of Immediate Postpartum Anaemia and Associated Factors among Postnatal Mothers in Northwest Ethiopia: A Cross-Sectional Study.
Authors: Abebaw A, Gudayu TW, Kelkay B Abstract Background: Anaemia is a major global health problem, especially in developing countries. Postpartum anaemia hurts both maternal and newborn baby health. Anaemia in pregnancy is sufficiently emphasized; however, very little attention has been paid to postpartum anaemia in Ethiopia. Therefore, this study aimed to investigate the proportion of immediate postpartum anaemia and associated factors among postpartum mothers in Debre Markos Referral Hospital. Methods: Institutional-based cross-sectional study was conducted among 424 study participants from August 1st to O...
Source: Anemia - July 2, 2020 Category: Hematology Tags: Anemia Source Type: research

Determinants of Anemia in Pregnancy: Findings from the Ethiopian Health and Demographic Survey.
This study was based on the 2016 Ethiopian Demographic Health Survey (EDHS) that used a two-stage stratified cluster sampling technique. A cross-sectional study was conducted among 3080 pregnant women. Data analysis was done using STATA v.14. Variables with P value
Source: Anemia - June 24, 2020 Category: Hematology Tags: Anemia Source Type: research

Leucocytosis and Asymptomatic Urinary Tract Infections in Sickle Cell Patients at a Tertiary Hospital in Zambia.
This study aimed to determine the prevalence of UTIs and haematological and kidney function profiles among SCA patients at the University Teaching Hospitals, Lusaka, Zambia. This was a cross-sectional study conducted between April and July 2019 involving 78 SCA patients who presented at the UTH. Blood and midstream urine samples were collected from each participant using the standard specimen collection procedures. Full blood counts and kidney function tests were determined using Sysmex XT-4000i haematology analyser and the Pentra C200 by Horiba, respectively. Bacterial profiles of the urine samples were determined using c...
Source: Anemia - June 24, 2020 Category: Hematology Tags: Anemia Source Type: research

Prevalence, Severity, and Correlates of Anaemia in Pregnancy among Antenatal Attendees in Warri, South-Southern Nigeria: A Cross-Sectional and Hospital-Based Study.
Conclusion: Based on the findings from our study, anaemia in pregnancy is still of primary public health concern if WHO cutoff is used for the diagnosis. However, the reduction observed when less than 30% haematocrit was used tags our study zone to be of moderate severity. Although all variables lacked statistical significance, younger age, no formal education, and unemployment were highlighted to be predisposing factors. PMID: 32455008 [PubMed - as supplied by publisher] (Source: Anemia)
Source: Anemia - May 27, 2020 Category: Hematology Tags: Anemia Source Type: research

Assessment of Hematological Parameters in Malaria, among Adult Patients Attending the Bamenda Regional Hospital.
Authors: Omarine Nlinwe N, Nange TB Abstract Malaria, which is responsible for a substantial amount of deaths in endemic countries, has been shown to have both direct and indirect effects on the hematological parameters. Notwithstanding, some hematological parameters among populations living in malaria endemic regions have not been described consistently, as a standard for measuring malaria burden. Based on the above fact, this study was designed to assess some hematological changes and their diagnostic values in malaria infected patients. A total of 160 malaria positive adult patients, together with 81 healthy con...
Source: Anemia - May 7, 2020 Category: Hematology Tags: Anemia Source Type: research

Etiologies and Treatment Burden in Adult Patients with Pure Red Cell Aplasia: A Single-Center Experience and Review of Literature.
Conclusions: Treatment outcome of PRCA depended upon the causes and the types of treatment, and the burden of RBC transfusion was very high in patients with ESA and thymoma-associated PRCA. PMID: 32257434 [PubMed] (Source: Anemia)
Source: Anemia - April 9, 2020 Category: Hematology Tags: Anemia Source Type: research

Determinants of Anemia among HIV-Positive Children on Highly Active Antiretroviral Therapy Attending Hospitals of North Wollo Zone, Amhara Region, Ethiopia, 2019: A Case-Control Study.
Conclusion: In this study, having parasitic infections, having a history of opportunistic infections, being malnourished, having poor adherence to ART, caregivers living in the rural area, and eating nondiversified foods were significantly associated with hemoglobin status. Therefore, intervention aimed at prevention, early diagnosis, and treatment of anemia is essential in these patients. PMID: 32148954 [PubMed] (Source: Anemia)
Source: Anemia - March 10, 2020 Category: Hematology Tags: Anemia Source Type: research

Effect of Interleukin and Hepcidin in Anemia of Chronic Diseases.
Authors: Yacoub MF, Ferwiz HF, Said F Abstract Background: Anemia of chronic disease (ACD) also termed as the anemia of inflammation has been found to be associated with inflammations, chronic infections, and cancers, particularly in old age. Recent studies revealed that interleukin-6 (IL-6), a proinflammatory cytokine, and hepcidin, an antimicrobial hepatic peptide, play a key role in ACD pathogenesis. Patients and Methods. The study included 40 subjects with chronic diseases and 40 normal subjects of the same age group. Red cell indices, levels of IL-6 and hepcidin, and iron profile were measured in all participa...
Source: Anemia - February 26, 2020 Category: Hematology Tags: Anemia Source Type: research

An Analysis of Societal Determinant of Anemia among Adolescent Girls in Azad Jammu and Kashmir, Pakistan.
In this study, we explore the societal determinants of anemia among adolescent girls in Azad Jammu and Kashmir (AJK), Pakistan. A cross-sectional study was conducted in the Muzaffarabad division of AJK on randomly selected 626 adolescent girls. The data were collected using a pretested self-administered interview schedule comprising mainly closed-ended questions with a few open-ended questions. Descriptive statistics was computed for describing the data, and bivariate regression and logistic regression were used to determine the association of anemia with its societal determinants. Multiple linear regression is used to det...
Source: Anemia - February 13, 2020 Category: Hematology Tags: Anemia Source Type: research

District Effect Appraisal in East Sub-Saharan Africa: Combating Childhood Anaemia.
Conclusion: The ranking of the performance of the districts allows for the worst-performing districts to be targeted for further research in order to improve their anaemia control strategies, as well as for the best-performing districts to be identified to further determine why they are performing better and then to use these districts as role models in efforts to overcome childhood anaemia. PMID: 31885912 [PubMed] (Source: Anemia)
Source: Anemia - December 31, 2019 Category: Hematology Tags: Anemia Source Type: research

REGAIN STUDY: Retrospective Study to Assess the Effectiveness, Tolerability, and Safety of Ferric Carboxymaltose in the Management of Iron Deficiency Anemia in Pregnant Women.
Authors: Wani S, Noushad M, Ashiq S Abstract Iron deficiency anemia (IDA) during pregnancy arises because of preexisting inadequate stores or complex physiological changes and can lead to serious maternal and fetal complications. Oral iron, either as iron sulfate or fumarate, with or without folic acid, is the most commonly used treatment for IDA in pregnancy. Intravenous (IV) iron has a role in the treatment of IDA in pregnancy, particularly in women who present late, display severe anemia (Hb ≤ 9 g/dL), or risk factors, and are intolerant/noncompliant of oral iron. Previously, administrati...
Source: Anemia - December 1, 2019 Category: Hematology Tags: Anemia Source Type: research

Anemia Prevalence after Iron Supplementation among Pregnant Women in Midwifes Practice of Primary Health Care Facilities in Eastern Indonesia.
Conclusion: Assessment of Shine and Lal index as the first step to screen the type of anemia in pregnant women from a limited area is of potential value, especially because Indonesia is located in the thalassemia belt area. An integrative approach and counseling among pregnant women with β-TT and their partners will increase thalassemia awareness and optimal birth management. PMID: 31772773 [PubMed] (Source: Anemia)
Source: Anemia - November 28, 2019 Category: Hematology Tags: Anemia Source Type: research

Risk Factors of Anaemia among Children under Five Years in the Hohoe Municipality, Ghana: A Case Control Study.
We examined the risk factors of anaemia among children under five years in the Hohoe Municipality, Ghana. Methods: This facility-based matched case control study recruited 210 children (70 cases and 140 controls) aged 6 to 59 months. Stratified and simple random sampling techniques were used to select mothers attending Child Welfare Clinic (CWC) for the screening of their children. Data were collected using a semistructured questionnaire. Finger prick blood was collected to estimate the haemoglobin (Hb) level and thick film was prepared to determine malaria parasitaemia. Axillary temperature was measured using an +elec...
Source: Anemia - July 27, 2019 Category: Hematology Tags: Anemia Source Type: research

A Comparative Study of Interleukin 6, Inflammatory Markers, Ferritin, and Hematological Profile in Rheumatoid Arthritis Patients with Anemia of Chronic Disease and Iron Deficiency Anemia.
Conclusion: IL-6 and ferritin level estimation may be workable tests to differentiate the patients with IDA and ACD in RA. PMID: 31057960 [PubMed] (Source: Anemia)
Source: Anemia - May 7, 2019 Category: Hematology Tags: Anemia Source Type: research

Iron Deficiency Anemia among In-School Adolescent Girls in Rural Area of Bahir Dar City Administration, North West Ethiopia.
Authors: Mengistu G, Azage M, Gutema H Abstract Background: Anemia is a major public health problem worldwide. Adolescent girls are the most vulnerable group of population due to different reasons. The aim of this study was to assess the prevalence of anemia and associated factors among school adolescent girls in rural towns of Bahir Dar City Administration, North West Ethiopia. Methods: A cross-sectional study was conducted from March 5 to April 15, 2017, on 443 randomly selected school adolescent girls. Data were collected using pretested structured questionnaire and anthropometric measurements. Blood sample ...
Source: Anemia - April 26, 2019 Category: Hematology Tags: Anemia Source Type: research

Comorbidity of Glucose-6-Phosphate Dehydrogenase Deficiency and Sickle Cell Disease Exert Significant Effect on RBC Indices.
Conclusion: From the results obtained, it implies that G6PD deficiency may increase the severity of anaemia in SCD patients. There is therefore the need to screen all SCD patients for G6PD deficiency to ensure that their condition is not exacerbated during treatment. PMID: 31016042 [PubMed] (Source: Anemia)
Source: Anemia - April 26, 2019 Category: Hematology Tags: Anemia Source Type: research

Corrigendum to "Efficacy and Tolerability of Intravenous Ferric Carboxymaltose in Patients with Iron Deficiency at a Hospital Outpatient Clinic: A Retrospective Cohort Study of Real-World Clinical Practice".
Corrigendum to "Efficacy and Tolerability of Intravenous Ferric Carboxymaltose in Patients with Iron Deficiency at a Hospital Outpatient Clinic: A Retrospective Cohort Study of Real-World Clinical Practice". Anemia. 2019;2019:9242607 Authors: Robalo Nunes A, Palricas Costa A, Rocha SL, Garcia de Oliveira A Abstract [This corrects the article DOI: 10.1155/2017/3106890.]. PMID: 30713774 [PubMed - in process] (Source: Anemia)
Source: Anemia - February 5, 2019 Category: Hematology Tags: Anemia Source Type: research

Prevalence of Anemia and Iron Deficiency among Palestinian Pregnant Women and Its Association with Pregnancy Outcome.
Conclusion: Iron deficiency is a moderate public health problem among the study subjects. Maternal Hb and serum ferritin significantly affect pregnancy outcomes. PMID: 30675398 [PubMed] (Source: Anemia)
Source: Anemia - January 26, 2019 Category: Hematology Tags: Anemia Source Type: research

Magnitude of Anemia and Associated Factors among Pregnant Women Attending Antenatal Care in Public Hospitals of Ilu Abba Bora Zone, South West Ethiopia: A Cross-Sectional Study.
Conclusions: The magnitude of anemia among pregnant women was found to be significant. Residence, family sizes, history of malaria infection during the last one year, and undernourishment were significantly associated with anemia during pregnancy. PMID: 30538862 [PubMed] (Source: Anemia)
Source: Anemia - December 14, 2018 Category: Hematology Tags: Anemia Source Type: research

Anemia among Women Attending Antenatal Care at the University of Gondar Comprehensive Specialized Referral Hospital, Northwest Ethiopia, 2017.
Conclusion and Recommendations: The prevalence of anemia among pregnant women attending the University of Gondar Referral Hospital was a moderate public health problem. Unprotected water source, large family size, Human Immunodeficiency Virus infection, and repeated pregnancies were factors that predicted anemia. Thus, prevention of Human Immunodeficiency Virus infection, family planning utilization, and accessing pure water are recommended. PMID: 30402283 [PubMed] (Source: Anemia)
Source: Anemia - November 9, 2018 Category: Hematology Tags: Anemia Source Type: research

Efficacy of Oral Acetaminophen and Intravenous Chlorpheniramine Maleate versus Placebo to Prevent Red Cell Transfusion Reactions in Children and Adolescent with Thalassemia: A Prospective, Randomized, Double-Blind Controlled Trial.
Conclusion: Administration of premedications in thalassemia patients receiving RBC transfusion without a history of transfusion reactions does not decrease the overall risk of transfusion reactions. However, the use of CPM might be beneficial to prevent delayed urticarial rash in those patients especially in females (Thai Clinical Trial Registry (TCTR) study ID: 20140526001). PMID: 30364108 [PubMed] (Source: Anemia)
Source: Anemia - October 28, 2018 Category: Hematology Tags: Anemia Source Type: research

Determinants of Anemia among Pregnant Women Attending Antenatal Clinic in Public Health Facilities at Durame Town: Unmatched Case Control Study.
Conclusion: Parasitic infection, additional diet during pregnancy, consuming tea/coffee immediately after food, meat consumption, previous heavy menstrual blood flow, and occupational status of women were significant factors associated with anemia among pregnant women. Therefore, anemia prevention strategy should include promotion of counseling on additional diet during pregnancy, preventing parasitic infection, and increasing employment opportunities for women. PMID: 30345112 [PubMed] (Source: Anemia)
Source: Anemia - October 24, 2018 Category: Hematology Tags: Anemia Source Type: research

Evaluation of Iron Deficiency Anemia Frequency as a Risk Factor in Glaucoma.
Authors: Firat PG, Demirel EE, Dikci S, Kuku I, Genc O Abstract Purpose: Iron deficiency anemia is an important public health problem. Also it is considered to be a risk factor for many diseases. The study demonstrates the iron deficiency anemia frequency in glaucoma patients and compares with the normal subjects. We aimed to determine the iron deficiency anemia frequency in glaucoma patients. Methods: Prospective, controlled study in a single university hospital setting. A total of 130 normal subjects (Group 1) and 131 glaucoma patients (Group 2) were included. The erythrocytes parameters, hemoglobin, red bloo...
Source: Anemia - August 31, 2018 Category: Hematology Tags: Anemia Source Type: research

Burden and Determinants of Anemia in a Rural Population in South India: A Cross-Sectional Study.
Authors: Little M, Zivot C, Humphries S, Dodd W, Patel K, Dewey C Abstract Background/Objectives: To determine the prevalence and determinants of blood haemoglobin level and mild, moderate, and severe anemia in a sample of adults from rural Tamil Nadu, India. Subjects/Methods: We recruited a sample of men and nonpregnant women aged 20 years and older. Clinical health measures included blood haemoglobin concentration and body mass index. We assessed associations between anemia outcomes and sociodemographic and dietary factors using linear and logistic regression modeling. Results: A total of 753 individuals ...
Source: Anemia - August 18, 2018 Category: Hematology Tags: Anemia Source Type: research

Multilevel Analysis of Determinants of Anemia Prevalence among Children Aged 6-59 Months in Ethiopia: Classical and Bayesian Approaches.
Conclusion: The current study confirmed that prevalence of anemia among children aged 6-59 months in Ethiopia was severe public health problem, where 42.8% of them are anemic. Thus, stakeholders should pay attention to all significant factors mentioned in the analysis of this study but wealth index/improving household income and availability of pure drinking water are the most influential factors that should be improved anyway. PMID: 29973986 [PubMed] (Source: Anemia)
Source: Anemia - July 6, 2018 Category: Hematology Tags: Anemia Source Type: research

Association of Colecalciferol, Ferritin, and Anemia among Pregnant Women: Result from Cohort Study on Vitamin D Status and Its Impact during Pregnancy and Childhood in Indonesia.
Authors: Judistiani RTD, Gumilang L, Nirmala SA, Irianti S, Wirhana D, Permana I, Sofjan L, Duhita H, Tambunan LA, Gurnadi JI, Seno U, Ghrahani R, Indrati AR, Sribudiani Y, Yuniati T, Setiabudiawan B Abstract Studies had shown that iron-cycling was disturbed by inflammatory process through the role of hepcidin. Pregnancy is characterized by shifts of interleukin. Our objective was to determine if 25(OH) vitamin D (colecalciferol) status was associated with ferritin, anemia, and its changes during pregnancy. Method. A cohort study was done in 4 cities in West Java, Indonesia, beginning in July 2016. Subjects were fo...
Source: Anemia - June 13, 2018 Category: Hematology Tags: Anemia Source Type: research

Anaemia in Pregnancy: Prevalence, Risk Factors, and Adverse Perinatal Outcomes in Northern Tanzania.
Conclusion: Anaemia in pregnancy was a mild public health problem in the study setting of Northern Tanzania. PMID: 29854446 [PubMed] (Source: Anemia)
Source: Anemia - June 3, 2018 Category: Hematology Tags: Anemia Source Type: research

Prevalence of Iron Deficiency Anemia among University Students in Hodeida Province, Yemen.
Authors: Al-Alimi AA, Bashanfer S, Morish MA Abstract Background: Iron deficiency anemia (IDA) is one of the most common types of nutritional anemia in the worldwide and considered a major public health problem in developing countries especially in Yemen. Therefore, this cross-sectional study was conducted to determine the prevalence and risk factors of IDA among apparently healthy Yemeni students at Hodeida University. Method: Five hundred blood samples (326 males and 174 females) were collected randomly from medical students at Hodeida University. Participants were subjected to different tests including compl...
Source: Anemia - June 2, 2018 Category: Hematology Tags: Anemia Source Type: research

Frequency of Anemia and Iron Deficiency among Children Starting First Year of School Life and Their Association with Weight and Height.
The objectives of the study were to ascertain frequency of anemia and iron deficiency among children starting first year of school life and test association with height and weight. One in four children starting first year of school life in five schools of Rabwah, Pakistan, was included. Full blood counts and ferritin levels of the children included in the study were checked. Status of their height and weight was determined according to Z-score charts. Chi-square test was used to test association. Two hundred and ninety-five children with median age of 67 months were included in the study. Out of 295, 240 (81.4%) had normal...
Source: Anemia - June 2, 2018 Category: Hematology Tags: Anemia Source Type: research

Relation of Food Insecurity and Hemoglobin Level in Preschool Aged Children.
Conclusion: The prevalence of anemia of 19.2% and the household food insecurity was found among 42.2% of the population. PMID: 29568649 [PubMed] (Source: Anemia)
Source: Anemia - March 25, 2018 Category: Hematology Tags: Anemia Source Type: research

Efficacy and Tolerability of Intravenous Ferric Carboxymaltose in Patients with Iron Deficiency at a Hospital Outpatient Clinic: A Retrospective Cohort Study of Real-World Clinical Practice.
Authors: Robalo Nunes A, Palricas Costa A, Rocha SL, Garcia de Oliveira A Abstract Ferric carboxymaltose (FCM) is an intravenous iron formulation to correct iron deficiency. Although its use has been extensively studied in clinical trials, real-world evidence regarding FCM treatment is scarce. Our aim was to evaluate the efficacy and tolerability of FCM treatment in patients with iron deficiency, with or without anemia, at a hospital outpatient clinic. Data was collected retrospectively from medical records. During this 2-year study, 459 patients were included. Mean age was 58.6 ± 17.5 years and most patient...
Source: Anemia - August 2, 2017 Category: Hematology Tags: Anemia Source Type: research

Low Hemoglobin among Pregnant Women in Midwives Practice of Primary Health Care, Jatinangor, Indonesia: Iron Deficiency Anemia or β-Thalassemia Trait?
Low Hemoglobin among Pregnant Women in Midwives Practice of Primary Health Care, Jatinangor, Indonesia: Iron Deficiency Anemia or β-Thalassemia Trait? Anemia. 2017;2017:6935648 Authors: Susanti AI, Sahiratmadja E, Winarno G, Sugianli AK, Susanto H, Panigoro R Abstract Low hemoglobin (Hb) or anemia is common among pregnant women in developing countries which may cause adverse pregnancy outcomes and maternal deaths. Our study aimed to assess Hb level measured by midwives in primary health care facility at rural area of Jatinangor, Indonesia, and to explore whether the anemia was due to iron deficien...
Source: Anemia - June 23, 2017 Category: Hematology Tags: Anemia Source Type: research

Ferric Carboxymaltose as Treatment in Women with Iron-Deficiency Anemia.
Conclusion. FCM was well tolerated and effectively increased mean hemoglobin levels in postpartum women or women with heavy menstrual bleeding and IDA. This trial is registered with ClinicalTrials.gov, NCT00548860. PMID: 28487769 [PubMed] (Source: Anemia)
Source: Anemia - May 12, 2017 Category: Hematology Tags: Anemia Source Type: research

Factors Associated with Growth Retardation in Children Suffering from Sickle Cell Anemia: First Report from Central Africa.
Conclusion. Nutritional status encountered in Congolese sickle cell children has been described for the first time in this study. A high prevalence of poor growth in SCA children was found in our study. PMID: 28250985 [PubMed] (Source: Anemia)
Source: Anemia - March 4, 2017 Category: Hematology Tags: Anemia Source Type: research

Prevalence, Severity, and Determinant Factors of Anemia among Pregnant Women in South Sudanese Refugees, Pugnido, Western Ethiopia.
Conclusion. More than one-third of pregnant women had anemia in this study. Intervention based strategies on identified determinant factors will be very important to combat anemia among the group. PMID: 28058116 [PubMed] (Source: Anemia)
Source: Anemia - January 7, 2017 Category: Hematology Tags: Anemia Source Type: research

Malaria, Moderate to Severe Anaemia, and Malarial Anaemia in Children at Presentation to Hospital in the Mount Cameroon Area: A Cross-Sectional Study.
Conclusion. Being febrile was the only predictor of both MdSA and MdSMA. More haematological insult occurred in children with MdSMA compared to MdSA. PMID: 27895939 [PubMed - in process] (Source: Anemia)
Source: Anemia - December 1, 2016 Category: Hematology Tags: Anemia Source Type: research

Using Soluble Transferrin Receptor and Taking Inflammation into Account When Defining Serum Ferritin Cutoffs Improved the Diagnosis of Iron Deficiency in a Group of Canadian Preschool Inuit Children from Nunavik.
Authors: Turgeon O'Brien H, Blanchet R, Gagné D, Lauzière J, Vézina C Abstract The prevalence of iron depletion, iron deficient erythropoiesis (IDE), and iron deficiency anemia (IDA) was assessed in preschool Inuit children using soluble transferrin receptor (sTfR) and traditional indicators of iron status while disregarding or taking inflammation into account when defining SF cutoffs. Iron depletion was defined as follows: (1) SF
Source: Anemia - July 7, 2016 Category: Hematology Tags: Anemia Source Type: research

Transfusion Thresholds, Quality of Life, and Current Approaches in Myelodysplastic Syndromes.
Authors: Koutsavlis I Abstract Hemoglobin thresholds and triggers for blood transfusions have changed over the years moving from a higher to a lower level. This review article summarizes the current evidence of transfusion thresholds in the hospitalized as well as in the outpatient setting and particularly in myelodysplasia. Fatigue is the main reported symptom in this group of patients and current clinical trials are looking for a more liberal approach of red cell transfusion and the effect on quality of life as opposed to the restrictive strategy used in the critical care setting. Practical considerations, the co...
Source: Anemia - May 20, 2016 Category: Hematology Tags: Anemia Source Type: research

Magnitude of Anemia and Hematological Predictors among Children under 12 Years in Odisha, India.
Conclusion. The prevalence of anemia was higher with concomitant acute infection among study population, which is a matter of concern. Since the hematological parameters are interrelated with each other as well as with the age and gender, relevant intervention strategy and constant monitoring are needed while providing public health nutrition programs to eradicate anemia. PMID: 27127647 [PubMed] (Source: Anemia)
Source: Anemia - May 1, 2016 Category: Hematology Tags: Anemia Source Type: research

Absolute Reticulocyte Count and Reticulocyte Hemoglobin Content as Predictors of Early Response to Exclusive Oral Iron in Children with Iron Deficiency Anemia.
We report data regarding kinetic of response to oral iron in 34 iron deficiency anemia children. Twenty-four/34 patients (70.5%) reached reference value of hemoglobin (Hb) concentration for age and sex at day + 30 from the beginning of treatment (complete early responders (CERs)), and 4/34 (12%) reached an Hb concentration at least 50% higher than the original (partial early responders (PERs)). CHr at T1 (within 7 days from the beginning of treatment) was significantly different in the different groups (22.95 in CERs versus 18.41 in other patients; p = 0.001; 22.42 in early responders versus 18.07 in NERs; p = 0.001). Rela...
Source: Anemia - April 20, 2016 Category: Hematology Tags: Anemia Source Type: research

Erythropoiesis in Malaria Infections and Factors Modifying the Erythropoietic Response.
Authors: Pathak VA, Ghosh K Abstract Anemia is the primary clinical manifestation of malarial infections and is responsible for the substantial rate of morbidity. The pathophysiology discussed till now catalogued several causes for malarial anemia among which ineffective erythropoiesis being remarkable one occurs silently in the bone marrow. A systematic literature search was performed and summarized information on erythropoietic response upon malaria infection and the factors responsible for the same. This review summarizes the clinical and experimental studies on patients, mouse models, and in vitro cell cultures...
Source: Anemia - April 3, 2016 Category: Hematology Tags: Anemia Source Type: research