Age-stratified association of blood pressure with albuminuria and left ventricular hypertrophy in patients with hypertension and diabetes mellitus
Blood Press. 2021 Feb 23:1-8. doi: 10.1080/08037051.2021.1889967. Online ahead of print.ABSTRACTPURPOSE: We investigated associations of blood pressure (BP) with albuminuria and left ventricular hypertrophy (LVH) in young, middle and older aged patients with hypertension and/or diabetes mellitus.MATERIALS & METHODS: Study participants were treated patients with hypertension or diabetes, enrolled in a China nationwide registry. The 2510 patients were classified into young (
Source: Blood Pressure - February 24, 2021 Category: Hematology Authors: Wei Zhang Chang-Yuan Liu Li-Nong Ji Ji-Guang Wang ATTEND Investigators Source Type: research

Intrarenal hemodynamics and kidney function in pheochromocytoma and paraganglioma before and after surgical treatment.
CONCLUSIONS: In contrast to patients with other forms of secondary hypertension, our study did not show differences in intrarenal blood flow parameters and renal function between PPGL and non-PPGL subjects. Intrarenal hemodynamics and renal function did not change after normalisation of catecholamine levels by surgical treatment. PMID: 33586556 [PubMed - as supplied by publisher] (Source: Blood Pressure)
Source: Blood Pressure - February 17, 2021 Category: Hematology Tags: Blood Press Source Type: research

Cardiac autonomic modulation in patients with type 2 diabetes.
Authors: Silva LPD, Seixas MB PMID: 33517798 [PubMed - as supplied by publisher] (Source: Blood Pressure)
Source: Blood Pressure - February 3, 2021 Category: Hematology Tags: Blood Press Source Type: research

Blood pressure target in patients with hypertension and type-2 diabetes older than 65 years. Is < 130/80  mmHg the right target or an excessive objective preventing from achieving the clinical goals we are aiming at?
Blood pressure target in patients with hypertension and type-2 diabetes older than 65 years. Is
Source: Blood Pressure - January 31, 2021 Category: Hematology Tags: Blood Press Source Type: research

Ethnic and sex differences in the longitudinal association between heart rate variability and blood pressure.
We examined this association in 387 normotensive young adults (mean age, 23 years, 52% female, 54% Black) who participated in two laboratory evaluations spanning approximately six years. Blood pressure was measured at both timepoints with a non-invasive oscillometric device and heart rate variability was assessed via bio-impedance. RESULTS: In the total sample, heart rate variability significantly predicted systolic (p = .022) and diastolic (p
Source: Blood Pressure - January 30, 2021 Category: Hematology Tags: Blood Press Source Type: research

Cardiovascular outcomes at recommended blood pressure targets in middle-aged and elderly patients with type 2 diabetes mellitus and hypertension.
Authors: Olsen E, Holzhauer B, Julius S, Kjeldsen SE, Larstorp ACK, Mancia G, Mehlum MH, Mo R, Rostrup M, Søraas CL, Zappe D, Weber MA Abstract PURPOSE: Available data of event-based clinical outcomes trials show that little evidence supports the guidelines recommendations to lower blood pressure (BP) to
Source: Blood Pressure - January 8, 2021 Category: Hematology Tags: Blood Press Source Type: research

Cardiovascular outcomes at recommended blood pressure targets in middle-aged and elderly patients with type 2 diabetes mellitus compared to all middle-aged and elderly hypertensive study patients with high cardiovascular risk.
Authors: Olsen E, Holzhauer B, Julius S, Kjeldsen SE, Larstorp ACK, Mancia G, Mehlum MH, Mo R, Rostrup M, Søraas CL, Zappe D, Weber MA Abstract PURPOSE: Event-based clinical outcome trials have shown limited evidence to support guidelines recommendations to lower blood pressure (BP) to
Source: Blood Pressure - January 8, 2021 Category: Hematology Tags: Blood Press Source Type: research

Changes in sympathetic nervous system activity after renal denervation: results from the randomised Oslo RDN study.
CONCLUSION: Our data suggest that RDN reduces SNS activity after six months. This finding warrants investigation in a larger study. Clinical Trial Number registered at www.clinicaltrials.gov: NCT01673516. PMID: 33399016 [PubMed - as supplied by publisher] (Source: Blood Pressure)
Source: Blood Pressure - January 7, 2021 Category: Hematology Tags: Blood Press Source Type: research

Association of lifetime blood pressure with adulthood exercise blood pressure response: the cardiovascular risk in young Finns study.
CONCLUSIONS: These findings reinforce the importance of achieving and sustaining normal blood pressure from childhood through adulthood. PMID: 33399019 [PubMed - as supplied by publisher] (Source: Blood Pressure)
Source: Blood Pressure - January 7, 2021 Category: Hematology Tags: Blood Press Source Type: research

Familial hyperaldosteronism type 1 and pregnancy: successful treatment with low dose dexamethasone.
CONCLUSIONS: Based on this experience and on available information on pathophysiology of FH-1 in pregnancy, the pros and cons of dexamethasone administration in the treatment of FH-1 in pregnancy are also discussed. PMID: 33390031 [PubMed - as supplied by publisher] (Source: Blood Pressure)
Source: Blood Pressure - January 5, 2021 Category: Hematology Tags: Blood Press Source Type: research

Potential protective effects of antihypertensive treatments during the Covid-19 pandemic: from inhibitors of the renin-angiotensin system to beta-adrenergic receptor blockers.
Authors: Kjeldsen SE, Narkiewicz K, Burnier M, Oparil S PMID: 33349063 [PubMed - as supplied by publisher] (Source: Blood Pressure)
Source: Blood Pressure - December 24, 2020 Category: Hematology Tags: Blood Press Source Type: research

In memoriam: Ji ří Widimský Sr. 1925-2020.
In memoriam: Jiří Widimský Sr. 1925-2020. Blood Press. 2020 Dec 21;:1-3 Authors: Kreutz R, Cífková R, Kjeldsen SE, Narkiewicz K, Burnier M, Oparil S, Mancia G PMID: 33342305 [PubMed - as supplied by publisher] (Source: Blood Pressure)
Source: Blood Pressure - December 22, 2020 Category: Hematology Tags: Blood Press Source Type: research

Serum uric acid and blood pressure among adolescents: data from the Nutrition and Health Survey in Taiwan (NAHSIT) 2010-2011.
CONCLUSION: Adolescents with factors as male, obesity, and UA ≥5.5 mg/dL were prone to have an elevated BP, regardless of age and family history of hypertension. The present study found that serum UA levels are significantly correlated to BP in Taiwanese adolescents. PMID: 33215542 [PubMed - as supplied by publisher] (Source: Blood Pressure)
Source: Blood Pressure - November 22, 2020 Category: Hematology Tags: Blood Press Source Type: research

In memoriam: Peter Sleight 1929-2020.
Authors: Kreutz R, Kjeldsen SE, Burnier M, Narkiewicz K, Oparil S, Mancia G PMID: 33153320 [PubMed - as supplied by publisher] (Source: Blood Pressure)
Source: Blood Pressure - November 11, 2020 Category: Hematology Tags: Blood Press Source Type: research

Was it optimal to drop a diuretic as a first-line choice of drug treatment in the 2020 International Society of Hypertension Guidelines?
Authors: Kjeldsen SE, Narkiewicz K, Burnier M, Oparil S PMID: 33140684 [PubMed - as supplied by publisher] (Source: Blood Pressure)
Source: Blood Pressure - November 5, 2020 Category: Hematology Tags: Blood Press Source Type: research

Treatment effect of lacidipine and amlodipine on clinic and ambulatory blood pressure and arteria stiffness in a randomised double-blind trial.
Authors: Wang Y, Li Y, Huo Y, Wang JG Abstract PURPOSE: In a randomised, double-blind trial, we investigated effects of lacidipine on clinic and ambulatory blood pressure (BP) and arterial stiffness in patients with mild-to-moderate hypertension, as compared with amlodipine. MATERIALS AND METHODS: Previously untreated and treated patients (n = 269, 50-80 years of age) with clinic hypertension (a clinic systolic/diastolic BP 140-180/
Source: Blood Pressure - November 4, 2020 Category: Hematology Tags: Blood Press Source Type: research

Professor Giuseppe Mancia receives the Excellence Research Award of the Council on Hypertension of the American Heart Association.
Authors: Kreutz R PMID: 33111596 [PubMed - as supplied by publisher] (Source: Blood Pressure)
Source: Blood Pressure - October 29, 2020 Category: Hematology Tags: Blood Press Source Type: research

The renin-angiotensin-system and left ventricular mass in young adults: the African-PREDICT study.
Authors: du Toit WL, Schutte AE, Gafane-Matemane LF, Kruger R, Mels CMC Abstract PURPOSE: Raised blood pressure, with the renin-angiotensin system (RAS) as a central regulatory component, is one of the most important contributors to early development of left ventricular hypertrophy. Factors such as increased age, sex, black ethnicity and a low socio-economic status also contribute to left ventricular remodelling. To better understand early contributors to left ventricular mass, we investigated the relationship between left ventricular mass index (LVMi) and the components of the RAS in young healthy adults while con...
Source: Blood Pressure - October 23, 2020 Category: Hematology Tags: Blood Press Source Type: research

Impact of obesity with or without hypertension on systemic haemodynamic and renal responses to lower body negative pressure.
CONCLUSIONS: These results show that the systemic and the renal response to LBNP differ according to weight and to BP categories. Systolic BP and heart show a progressive increased response form healthy volunteers to OBN and then to obese hypertensive participants while urinary output and free water clearance responses are increased in OBN only, suggesting that the occurrence of hypertension in obese individuals modifies the early kidney responses to stress. CLINICALTRIAL.GOV IDENTIFIER: NCT01734096. PMID: 33073631 [PubMed - as supplied by publisher] (Source: Blood Pressure)
Source: Blood Pressure - October 20, 2020 Category: Hematology Tags: Blood Press Source Type: research

Ambulatory blood pressure in relation to interaction between dietary sodium intake and serum uric acid in the young.
Authors: Zhang W, Xu JZ, Lu XH, Li H, Wang D, Wang JG Abstract PURPOSE: We hypothesise that dietary sodium intake interacts with serum uric acid to influence blood pressure (BP) in children and adolescents. In the present study, we investigated ambulatory BP in relation to hyperuricaemia, dietary sodium intake and their interaction in children and adolescents with hypertension. MATERIALS AND METHODS:  A total of 616 study participants were 10-24 years old and had primary hypertension diagnosed after admission in a specialised inpatient ward. Ambulatory BP monitoring was performed during hospitalisat...
Source: Blood Pressure - October 10, 2020 Category: Hematology Tags: Blood Press Source Type: research

The randomised Oslo study of renal denervation vs. Antihypertensive drug adjustments: efficacy and safety through 7 years of follow-up.
Authors: Bergland OU, Søraas CL, Larstorp ACK, Halvorsen LV, Hjørnholm U, Hoffman P, Høieggen A, Fadl Elmula FEM Abstract PURPOSE: The blood pressure (BP) lowering effect of renal sympathetic denervation (RDN) in treatment-resistant hypertension shows variation amongst the existing randomised studies. The long-term efficacy and safety of RDN require further investigation. For the first time, we report BP changes and safety up to 7 years after RDN, compared to drug adjustment in the randomised Oslo RDN study. MATERIALS AND METHODS: Patients with treatment-resistant hypertension, defined...
Source: Blood Pressure - October 10, 2020 Category: Hematology Tags: Blood Press Source Type: research

Response to the editorial: "the international society of hypertension guidelines 2020 - a new drug treatment recommendation in the wrong direction?"
Response to the editorial: "the international society of hypertension guidelines 2020 - a new drug treatment recommendation in the wrong direction?" Blood Press. 2020 Sep 28;:1-2 Authors: Poulter N, Williams B, Schutte AE, Unger T PMID: 32985929 [PubMed - as supplied by publisher] (Source: Blood Pressure)
Source: Blood Pressure - September 30, 2020 Category: Hematology Tags: Blood Press Source Type: research

How to measure retinal microperfusion in patients with arterial hypertension.
CONCLUSIONS: While none of described methods enables the simultaneous measurement of all microcirculatory parameters, certain techniques are widely used in arterial hypertension research, while others gain popularity in screening. PMID: 32969283 [PubMed - as supplied by publisher] (Source: Blood Pressure)
Source: Blood Pressure - September 26, 2020 Category: Hematology Tags: Blood Press Source Type: research

Value-based approach to blood pressure telemonitoring and remote counseling in hypertensive patients.
Authors: Ionov MV, Zhukova OV, Yudina YS, Avdonina NG, Emelyanov IV, Kurapeev DI, Zvartau NE, Konradi AO Abstract PURPOSE: Blood pressure telemonitoring and remote counselling (BPTM) improves blood pressure (BP) control in patients with hypertension (HTN). Studies assessing the efficacy of BPTM from a value-based perspective are lacking. We investigated whether BPTM fits all principles of the value-based approach (clinical and economic effectiveness, improvement in patient-reported outcome/experience measures (PROM/PREM)). MATERIALS AND METHODS: Two hundred and forty ambulatory patients with uncontrolled HTN we...
Source: Blood Pressure - September 23, 2020 Category: Hematology Tags: Blood Press Source Type: research

Systolic murmur in disguise: subclavian artery stenosis as an overlooked cause of missed case of hypertension.
In this report we present a case of missed hypertension due to subclavian artery stenosis. A 77 year-old female patient, initially thought as being normotensive, was referred to us due to newly discovered systolic heart murmur suspicious for aortic stenosis. We noted inter-arm blood pressure difference of 30 mmHg, with higher, hypertensive values on right arm. Further workup and medical imaging excluded aortic stenosis and revealed an asymptomatic, hemodynamically significant, stenosis of left subclavian artery. Due to absence of symptoms, the patient has been managed with conservative therapy for subclavian ...
Source: Blood Pressure - September 3, 2020 Category: Hematology Tags: Blood Press Source Type: research

The International Society of Hypertension Guidelines 2020 - a new drug treatment recommendation in the wrong direction?
Authors: Kjeldsen SE, Narkiewicz K, Burnier M, Oparil S PMID: 32808555 [PubMed - as supplied by publisher] (Source: Blood Pressure)
Source: Blood Pressure - August 20, 2020 Category: Hematology Tags: Blood Press Source Type: research

Renal sympathetic denervation lowers systemic vascular resistance in true treatment-resistant hypertension.
Authors: Bergo KK, Larstorp AC, Hoffmann P, Hjørnholm U, Cataliotti A, Høieggen A, Rostrup M, Fadl Elmula FEM Abstract PURPOSE: Renal sympathetic denervation (RDN) is again gaining interest as recent well-designed trials have demonstrated reduced ambulatory blood pressure (BP) after RDN. However, the hemodynamic mechanisms have not been elucidated. We aimed for the first time to investigate the effect of RDN on the "Hallmark of Hypertension" namely increased systemic vascular resistance index (SVRI). MATERIALS AND METHODS: We investigated SVRI change in patients with true treatment-resis...
Source: Blood Pressure - July 8, 2020 Category: Hematology Tags: Blood Press Source Type: research

Smoking and overweight associated with masked uncontrolled hypertension: a Hypertension Optimal Treatment (HOT) Sub-Study.
Authors: Holanger M, Kjeldsen SE, Jamerson K, Julius S, HOT Study investigators Abstract PURPOSE: The Hypertension Optimal Treatment (HOT) Study investigated the relationship between target office diastolic blood pressure (BP) ≤80, ≤85 or ≤90 mmHg and cardiovascular morbidity and mortality in 18,790 patients aged 50-80 years. The home BP sub-study enrolled 926 patients and the aim was to clarify whether the separation into the BP target groups in the office prevailed in the out-of-office setting. The present study aimed to identify variables that characterised masked uncontrolled hypertension...
Source: Blood Pressure - July 8, 2020 Category: Hematology Tags: Blood Press Source Type: research

Systemic vascular resistance predicts the development of hypertension: the cardiovascular risk in young Finns study.
Authors: Kähönen E, Lyytikäinen LP, Aatola H, Koivistoinen T, Haarala A, Sipilä K, Juonala M, Lehtimäki T, Raitakari OT, Kähönen M, Hutri-Kähönen N Abstract Purpose: To study whether systemic hemodynamics, especially systemic vascular resistance, predicts the development of hypertension and improves the risk prediction of incident hypertension beyond common risk factors in the risk models in young adults.Materials and methods: Typical risk factors for hypertension in the risk prediction models (systolic and diastolic blood pressure, parental history of hypertension, age,...
Source: Blood Pressure - July 2, 2020 Category: Hematology Tags: Blood Press Source Type: research

Evaluation of time delay between discovery of a high blood pressure in a health screening survey and hypertension diagnosis.
Conclusion: In conclusion, when an elevated blood pressure was discovered in elderly persons at a health screening, 70% of those received a hypertension diagnosis within 10 years, with a mean time to diagnosis of 5 years. Health care actions should be enforced to shorten this time lag both in terms of information to the individuals, as well as the handling of this patient group in primary care. PMID: 32603237 [PubMed - as supplied by publisher] (Source: Blood Pressure)
Source: Blood Pressure - July 2, 2020 Category: Hematology Tags: Blood Press Source Type: research

Ambulatory blood pressure monitoring by a novel cuffless device: a pilot study.
Authors: Scalise F, Margonato D, Sole A, Sorropago A, Sorropago G, Mancia G Abstract Purpose: Cuffless blood pressure (CL-BP) measurements are believed to be a potentially alternative to cuff-occlusion-based (C-BP) measurement. A new cuffless device was developed for ambulatory BP monitoring. We assessed the accuracy of a new CL-BP device compared to a standard oscillatory C-BP device over the 24 h.Materials and methods: Eighty-four consecutive patients were included in the study. BP was measured simultaneously by the CL-BP device and by a C-BP device over the 24 h. Calculations included 24 h m...
Source: Blood Pressure - July 2, 2020 Category: Hematology Tags: Blood Press Source Type: research

On-treatment HDL cholesterol predicts incident atrial fibrillation in hypertensive patients with left ventricular hypertrophy.
Conclusion: Lower on-treatment HDL is strongly associated with risk of new AF. These findings suggest that serial assessment of HDL can estimate AF risk better than baseline HDL in hypertensive patients with left ventricular hypertrophy. Future studies may investigate whether therapies that increase HDL can lower risk of developing AF.Clinical Trials Registration: http://clinicaltrials.gov/ct/show/NCT00338260?order=1. PMID: 32586143 [PubMed - as supplied by publisher] (Source: Blood Pressure)
Source: Blood Pressure - June 28, 2020 Category: Hematology Tags: Blood Press Source Type: research

Intensive systolic blood pressure control and prevention of new onset atrial fibrillation in the SPRINT study: is the association really controversial?
Authors: Kjeldsen SE, Narkiewicz K, Burnier M, Oparil S PMID: 32584173 [PubMed - as supplied by publisher] (Source: Blood Pressure)
Source: Blood Pressure - June 27, 2020 Category: Hematology Tags: Blood Press Source Type: research

Antihypertensive prescription patterns and cardiovascular risk in patients with newly diagnosed hypertension- an analysis of statutory health insurance data in Germany.
Conclusion: Initial treatment strategies may not always be stratified according to cardiovascular risk. The majority of patients with hypertension receives initial monotherapy independent of their individual risk. However, combination therapy represents the major form of therapy in the long-term. PMID: 32543915 [PubMed - as supplied by publisher] (Source: Blood Pressure)
Source: Blood Pressure - June 18, 2020 Category: Hematology Tags: Blood Press Source Type: research

Changes of augmentation index early after ischaemic stroke predict functional outcome.
Conclusions: Rise in AIx within one week after ischaemic stroke may be of additional importance in determining better early and late favourable functional outcome. PMID: 32456469 [PubMed - as supplied by publisher] (Source: Blood Pressure)
Source: Blood Pressure - May 29, 2020 Category: Hematology Tags: Blood Press Source Type: research

Subclinical macroangiopathic target organ damage in type 1 diabetes mellitus patients.
Conclusions: There is shortage of data from prospective studies which could confirm the benefits of early treatment initiation based on the presence of the subclinical organ damage in T1DM. Most evidence comes from T2DM trials, where effective preventive measures were identified i.e.: smoking cessation, reasonable blood glucose control, efficacious hypertension treatment, and dyslipidemia management, as well as renoprotection. There is still a field for further research to see if routine assessment of asymptomatic vascular damage and early implementation of aggressive treatment would reduce mortality excess from CVD in T1D...
Source: Blood Pressure - May 29, 2020 Category: Hematology Tags: Blood Press Source Type: research

Impending hypertensive emergency is frequently considered in guidelines, but neither defined nor explained.
Authors: Koracevic G, Stojanovic M, Lovic D, Djordjevic D PMID: 32441140 [PubMed - as supplied by publisher] (Source: Blood Pressure)
Source: Blood Pressure - May 23, 2020 Category: Hematology Tags: Blood Press Source Type: research

Longitudinal trends in the prevalence of hyperuricaemia and chronic kidney disease in hypertensive and normotensive adults.
Authors: Krajčoviechová A, Wohlfahrt P, Bruthans J, Šulc P, Lánská V, Borghi C, Cífková R Abstract The purpose: To evaluate longitudinal trends in the prevalence of hyperuricaemia and chronic kidney disease (CKD) in Czech adults with and without arterial hypertension (HT).Materials and methods: Two independent cross-sectional surveys were performed in 2006-2009 and 2015-2018, each screening involving 1% population random sample of the general population of nine districts of the Czech Republic aged 25-64 years, stratified by age and gender. Hyperuricaemia was defined...
Source: Blood Pressure - May 20, 2020 Category: Hematology Tags: Blood Press Source Type: research

Subtypes of masked hypertension and target organ damage in untreated outpatients.
Authors: Zhang DY, Cheng YB, Guo QH, Wang Y, Sheng CS, Huang QF, An DW, Li MX, Huang JF, Xu TY, Wang JG, Li Y Abstract Purpose: Masked hypertension (MHT) is characterised as an office normotension in the presence of out-of-office hypertension, and can be further categorised as isolated daytime (dMHT), night-time (nMHT) or day-night MHT (dnMHT) according to the time when hypertension is present. MHT is associated with adverse cardiovascular outcome. However, no previous studies contrasted these MHT subtypes in their associations with target organ damage (TOD).Materials and methods: Consecutive untreated patients ref...
Source: Blood Pressure - May 15, 2020 Category: Hematology Tags: Blood Press Source Type: research

Assessment of adherence to diuretics and β-blockers by serum drug monitoring in comparison to urine analysis.
Conclusion: This study suggests that assessment of adherence can be performed more precisely on the basis of serum drug concentrations with individually calculated lower DRC than by using the TRR or qualitative urinalysis. PMID: 32400211 [PubMed - as supplied by publisher] (Source: Blood Pressure)
Source: Blood Pressure - May 15, 2020 Category: Hematology Tags: Blood Press Source Type: research

Factors associated with increase in blood pressure and incident hypertension in early midlife: the Hordaland Health Study.
Authors: Kringeland E, Tell GS, Midtbø H, Haugsgjerd TR, Igland J, Gerdts E Abstract Purpose: We aimed to identify sex-specific factors associated with increase in blood pressure (BP) and incident hypertension in early midlife.Materials and methods: 2,008 women and 1,610 men aged 40-43 years were followed for six years in the Hordaland Health Study. Participants taking antihypertensive medication at baseline were excluded. High-normal BP was defined as baseline BP 130-139/85-89 mmHg, and incident hypertension as BP≥140/90 mmHg or use of antihypertensive medication at follow-up.Results: During follow-up, a...
Source: Blood Pressure - May 15, 2020 Category: Hematology Tags: Blood Press Source Type: research

Results of renal artery revascularization in the post-ASTRAL era with 4 years mean follow-up.
Authors: Zachrisson K, Krupic F, Svensson M, Wigelius A, Jonsson A, Dimopoulou A, Stenborg A, Jensen G, Herlitz H, Gottsäter A, Falkenberg M Abstract Purpose: To investigate contemporary results of percutaneous transluminal renal angioplasty (PTRA).Materials and Methods: A multicentre retrospective study analysing all patients treated with PTRA for primary symptomatic renal artery stenosis (RAS) between 2010 and 2013 at four tertiary centres. Procedures during the preceding four years were counted to evaluate for change in PTRA frequency.Results: The number of PTRA procedures decreased by approximately 50% fro...
Source: Blood Pressure - May 6, 2020 Category: Hematology Tags: Blood Press Source Type: research

Prevalence, awareness, treatment and control of hypertension in various ethnic groups (Hui, Kazakh, Kyrgyz, Mongolian, Tajik) in Xinjiang, Northwest China.
Conclusions: Hypertension is moderately prevalent in Xinjiang, whereas poorly controlled. Standardization of its treatment such as introducing treatment algorithm might be the priorities for future improvement, with healthy life promotion. PMID: 32349556 [PubMed - as supplied by publisher] (Source: Blood Pressure)
Source: Blood Pressure - May 2, 2020 Category: Hematology Tags: Blood Press Source Type: research

Blood pressure medication should not be routinely dosed at bedtime. We must disregard the data from the HYGIA project.
Authors: Kreutz R, Kjeldsen SE, Burnier M, Narkiewicz K, Oparil S, Mancia G PMID: 32338542 [PubMed - as supplied by publisher] (Source: Blood Pressure)
Source: Blood Pressure - April 29, 2020 Category: Hematology Tags: Blood Press Source Type: research

Pulse wave velocity is related to exercise blood pressure response in young adults. The Cardiovascular Risk in Young Finns Study.
This study consisted of 209 young adults (mean age 38 years) who participated in the ongoing Cardiovascular Risk in Young Finns Study between 2007 and 2009. We measured resting PWV with impedance cardiography in 2007, and participants performed a maximal cardiopulmonary exercise test with blood pressure (BP) measurements at rest, during exercise and during recovery in 2008-2009.Results: High PWV (≥age- and sex-specific median) at baseline was associated with EEBP (SBP>210 mmHg for men and>190 mmHg for women) an average of 14 months later and with systolic BP during different stages of e...
Source: Blood Pressure - April 16, 2020 Category: Hematology Tags: Blood Press Source Type: research

Influence of pre-treatment blood pressure levels on antihypertensive drug benefits in diabetics: the roadmap experience.
Authors: Chatzikyrkou C, Scourt FG, Menne J, Korda A, Mertens PR, Haller H Abstract Purpose: Most guidelines for treatment of hypertension in the setting of diabetes recommend a blood pressure (BP) target of
Source: Blood Pressure - April 15, 2020 Category: Hematology Tags: Blood Press Source Type: research

Lumen narrowing and increased wall to lumen ratio of retinal microcirculation are valuable biomarkers of hypertension-mediated cardiac damage.
Authors: Dąbrowska E, Harazny JM, Miszkowska-Nagórna E, Stefański A, Graff B, Kunicka K, Świerblewska E, Rojek A, Szyndler A, Wolf J, Gruchała M, Schmieder RE, Narkiewicz K Abstract Purpose: In the course of hypertension, left ventricular hypertrophy and diastolic dysfunction develop very often and may progress toward heart failure. The aim of the study was to analyze the relationship between abnormalities of retinal microcirculation and cardiac damage defined as left ventricular hypertrophy and/or diastolic dysfunction.Materials and methods: The study comprised 88 patients with essential hypertension. T...
Source: Blood Pressure - April 2, 2020 Category: Hematology Tags: Blood Press Source Type: research

Effect of the shape of the cuff on blood pressure measurement in people with large arms.
Authors: Palatini P, Benetti E, Fania C, Ermolao A, Spinella P, Battista F, Gasperetti A, Saladini F Abstract Purpose: Previous data suggest that tronco-conical cuffs should be used for accurate blood pressure (BP) measurement in the obese. However, not only arm size but also its shape may affect the accuracy of BP measurement when a cylindrical cuff is used.Methods: In 197 subjects with arm circumference>32 cm, and 157 subjects with arm circumference ≤ 32 cm, the upper-arm was considered as formed from two truncated cones and the frustum slant angles of the proximal (upper angle) and distal (mi...
Source: Blood Pressure - March 17, 2020 Category: Hematology Tags: Blood Press Source Type: research

Association between antecedent blood pressure, hypertension-mediated organ damage and cardiovascular outcome.
The objective of this study was to test if combining antecedent systolic blood pressure (SBP) with traditional risk factors and hypertension-mediated organ damage (HMOD) improves risk stratification for subsequent cardiovascular disease.Materials and methods: 1910 subjects participated in this study. Antecedent SBP was defined as the average of measurements obtained in 1982 and in 1987. Current SBP was obtained in 1993. HMOD were examined in 1993. HMOD was defined as either atherosclerotic plaque(s), increased pulse wave velocity, increased urine albumin creatinine ratio (above the 90th percentile) or left ventricular hype...
Source: Blood Pressure - March 13, 2020 Category: Hematology Tags: Blood Press Source Type: research