Serum uric acid: a futile bystander in endothelial function?
CONCLUSION: In healthy or hypertensive adults with normal renal function, serum uric acid appears to be a futile bystander in endothelial function, oxidative stress, and arterial stiffness, in contrast to ageing, which reduces NO bioavailability. This study suggests that traditional factors such as ageing and hypertension should be the focus of clinical assessment and management of cardiovascular risk, rather than uric acid levels.PMID:37470459 | DOI:10.1080/08037051.2023.2237123 (Source: Blood Pressure)
Source: Blood Pressure - July 20, 2023 Category: Hematology Authors: Benjamin De Becker Philippe Van De Borne Source Type: research
Comparison of office, home and ambulatory blood pressure measurements in hypertensive and suspected hypertensive SWICOS participants
CONCLUSION: This population-based study found a high prevalence of WCH and potential uncontrolled hypertension among individuals with elevated OBPM. This study, therefore, supports the ESH recommendations of complementing OBPM by ABPM or HBPM. The use of HBPM instead of ABPM for the confirmation of hypertension in individuals with elevated OBPM might lead to underdiagnosis and uncontrolled hypertension, in particular in the younger working population. In these individuals, this study suggests using ABPM instead of HBPM.PMID:37452435 | DOI:10.1080/08037051.2023.2234496 (Source: Blood Pressure)
Source: Blood Pressure - July 14, 2023 Category: Hematology Authors: D Radovanovic F Muggli M Bianchetti A Gallino G Parati P M Suter R Schoenenberger-Berzins P Erne A W Schoenenberger Source Type: research
The impact of age on endothelial dysfunction measured by peripheral arterial tonometry in a healthy population-based cohort - the Malm ö offspring study
CONCLUSION: In a large healthy population, RHI < 1.67, an early marker of endothelial dysfunction, was more prevalent in younger individuals, implying that RHI might not be a suitable measure of endothelial function in individuals under 30 years of age. Our findings suggest that low RHI in young, healthy individuals may not necessarily indicate true ED but rather an artefact of the limited ability of young and healthy arteries to dilate post-occlusion. Therefore, the term "pseudo-ED" may be applicable to young individuals with low RHI values.PMID:37438962 | DOI:10.1080/08037051.2023.2234059 (Source: Blood Pressure)
Source: Blood Pressure - July 13, 2023 Category: Hematology Authors: A Jujic C Kenneb äck M Johansson P M Nilsson H Holm Source Type: research
Effect of antihypertensive treatment in isolated systolic hypertension (ISH) - systematic review and meta-analysis of randomised controlled trials
CONCLUSIONS: These findings support antihypertensive treatment of isolated systolic hypertension, regardless of baseline SBP, to target SBP <140 mmHg and even <130 mmHg if well tolerated.PMID:37395100 | DOI:10.1080/08037051.2023.2226757 (Source: Blood Pressure)
Source: Blood Pressure - July 3, 2023 Category: Hematology Authors: Mattias Brunstr öm Bo Carlberg Sverre E Kjeldsen Source Type: research
