Revisiting the role of measurable residual disease in FLT3 mutated acute myelogenous leukemia
Expert Rev Hematol. 2024 Apr 23. doi: 10.1080/17474086.2024.2347303. Online ahead of print.NO ABSTRACTPMID:38654593 | DOI:10.1080/17474086.2024.2347303 (Source: Expert Review of Hematology)
Source: Expert Review of Hematology - April 24, 2024 Category: Hematology Authors: H åkon Reikvam Richard Dillon Source Type: research

Frontline combination of dasatinib and low-intensity chemotherapy in adults with de novo Philadelphia chromosome-positive acute lymphoblastic leukemia
CONCLUSIONS: Our results suggest that dasatinib-based low-intensity chemotherapy is safe and effective as an induction strategy in the Chinese population. Allo-HSCT plays a crucial role in the long-term outcomes of patients with Ph+ ALL.CLINICAL TRIAL REGISTRATION: The trial was registered at ClinicalTrials.gov as NCT02690922.PMID:38616308 | DOI:10.1080/17474086.2024.2343885 (Source: Expert Review of Hematology)
Source: Expert Review of Hematology - April 14, 2024 Category: Hematology Authors: Yizhou Peng Jinjin Huang Jin Yin Fankai Meng Yang Cao Liang Huang Dengju Li Yicheng Zhang Donghua Zhang Li Meng Zhiqiang Han Zhenya Hong Source Type: research

Frontline combination of dasatinib and low-intensity chemotherapy in adults with de novo Philadelphia chromosome-positive acute lymphoblastic leukemia
CONCLUSIONS: Our results suggest that dasatinib-based low-intensity chemotherapy is safe and effective as an induction strategy in the Chinese population. Allo-HSCT plays a crucial role in the long-term outcomes of patients with Ph+ ALL.CLINICAL TRIAL REGISTRATION: The trial was registered at ClinicalTrials.gov as NCT02690922.PMID:38616308 | DOI:10.1080/17474086.2024.2343885 (Source: Expert Review of Hematology)
Source: Expert Review of Hematology - April 14, 2024 Category: Hematology Authors: Yizhou Peng Jinjin Huang Jin Yin Fankai Meng Yang Cao Liang Huang Dengju Li Yicheng Zhang Donghua Zhang Li Meng Zhiqiang Han Zhenya Hong Source Type: research

Curative effect of motherwort combined with ethinylestradiol-cyproterone acetate on dysfunctional uterine bleeding
CONCLUSION: Thecombination of motherwort and EE/CPA is clinically effective in thetreatment of DUB.PMID:38613836 | DOI:10.1080/17474086.2024.2343878 (Source: Expert Review of Hematology)
Source: Expert Review of Hematology - April 13, 2024 Category: Hematology Authors: Qiaoyun Tang Xueyuan Chen Source Type: research

Hemophagocytic lymphohistiocytosis in Egyptian children: diagnosis, treatment challenges, and outcome
CONCLUSIONS: This study confirms that the nonspecific signs and symptoms of HLH are challenging. Genetic testing, though expensive and sophisticated, is integral for the diagnosis. The difficulty in finding non-related donors for stem cell transplantation and the early reactivations are the causes of the inferior outcome.PMID:38597207 | DOI:10.1080/17474086.2024.2341044 (Source: Expert Review of Hematology)
Source: Expert Review of Hematology - April 10, 2024 Category: Hematology Authors: Azza A Tantawy Nayera H K Elsherif Solaf M Elsayed Heba G A Ali Sara M Makkeyah Hisham I E Elsantiel Genevi ève de Saint Basile Iman A Ragab Source Type: research

Hemophagocytic lymphohistiocytosis in Egyptian children: diagnosis, treatment challenges and outcome
CONCLUSIONS: This study confirms that the nonspecific signsand symptoms of HLH arechallenging. Genetic testing, though expensive and sophisticated, is integralfor the diagnosis. The difficulty in finding non-related donors for stem celltransplantation and the early reactivations are the causes of the inferioroutcome.PMID:38597207 | DOI:10.1080/17474086.2024.2341044 (Source: Expert Review of Hematology)
Source: Expert Review of Hematology - April 10, 2024 Category: Hematology Authors: Azza A Tantawy Nayera H K Elsherif Solaf M Elsayed Heba G A Ali Sara M Makkeyah Hisham I E Elsantiel Genevi ève de Saint Basile Iman A Ragab Source Type: research

Clinical characteristics of < em > HFE < /em > C282Y/H63D compound heterozygotes identified in a specialty practice: key differences from < em > HFE < /em > C282Y homozygotes
CONCLUSIONS: p.C282Y have a higher mobilizable iron and require more TP. p.C282Y/H63D likely require additional insults such as obesity or alcohol use to develop elevated ferritin. De-ironing may mitigate the risk of developing HC-related complications.PMID:38551816 | DOI:10.1080/17474086.2024.2337950 (Source: Expert Review of Hematology)
Source: Expert Review of Hematology - March 29, 2024 Category: Hematology Authors: Mukul Singal Amir Mahmoud Pradyumna Dinkar Phatak Source Type: research