Clinical characteristics of < em > HFE < /em > C282Y/H63D compound heterozygotes identified in a specialty practice: key differences from < em > HFE < /em > C282Y homozygotes

CONCLUSIONS: p.C282Y have a higher mobilizable iron and require more TP. p.C282Y/H63D likely require additional insults such as obesity or alcohol use to develop elevated ferritin. De-ironing may mitigate the risk of developing HC-related complications.PMID:38551816 | DOI:10.1080/17474086.2024.2337950
Source: Expert Review of Hematology - Category: Hematology Authors: Source Type: research