Development of BCG Scar and Subsequent Morbidity and Mortality in Rural Guinea-Bissau
Conclusions. Among BCG-vaccinated children in a setting with low scar prevalence, having a scar is associated with lower mortality and morbidity. BCG scar prevalence may be an important marker of vaccination program quality. (Source: Clinical Infectious Diseases)
Source: Clinical Infectious Diseases - August 27, 2015 Category: Infectious Diseases Authors: Storgaard, L., Rodrigues, A., Martins, C., Nielsen, B. U., Ravn, H., Benn, C. S., Aaby, P., Fisker, A. B. Tags: ARTICLES AND COMMENTARIES Source Type: research

Markers of iron status are associated with stage of pregnancy and acute-phase response, but not with parity among pregnant women in Guinea-Bissau.
Abstract While prenatal Fe supplementation prevents maternal Fe deficiency and anaemia, it is uncertain whether it improves infant health outcomes, at least when taken by Fe-replete women. Inflammation as well as physiological changes complicates the assessment of Fe status during pregnancy. In the present study, we measured the concentrations of serum ferritin and soluble transferrin receptors (sTfR), Hb and the acute-phase proteins C-reactive protein (CRP) and α1-antichymotrypsin (ACT) in a cross-sectional study among 738 pregnant women attending antenatal care in Guinea-Bissau, West Africa. Multiple li...
Source: The British Journal of Nutrition - August 19, 2015 Category: Nutrition Authors: Kæstel P, Aaby P, Ritz C, Friis H Tags: Br J Nutr Source Type: research

Cohort Profile: The Bissau HIV Cohort--a cohort of HIV-1, HIV-2 and co-infected patients
The West African country Guinea-Bissau is home to the world’s highest prevalence of HIV-2, and its HIV-1 prevalence is rising. Other chronic viral infections like human T-lymphotropic virus type 1 (HTLV-1) and hepatitis B virus are common as well. The Bissau HIV Cohort was started in 2007 to gain new insights into the overall effect of introducing antiretroviral treatment in a treatment-naïve population with concomitant infection with three retroviruses (HIV-1, HIV-2 and HTLV-1) and tuberculosis. The cohort includes patients from the HIV clinic at Hospital Nacional Simão Mendes, the main hospital in Bissa...
Source: International Journal of Epidemiology - July 30, 2015 Category: Epidemiology Authors: Jespersen, S., Honge, B. L., Oliveira, I., Medina, C., da Silva Te, D., Correira, F. G., Erikstrup, C., Laursen, A. L., Ostergaard, L., Wejse, C., for the Bissau HIV Cohort study group Tags: Cohort Profiles Source Type: research

Health Beliefs and Perceptions of Trachoma in Communities on the Bijagos Archipelago of Guinea Bissau
Ophthalmic Epidemiology, Volume 22, Issue 3, Page 190-199, June 2015. (Source: Ophthalmic Epidemiology)
Source: Ophthalmic Epidemiology - July 9, 2015 Category: Opthalmology Tags: article Source Type: research

[Health Communication: Preventing the Spread of Ebola Virus Disease in the Portuguese Spoken African Countries - Methodology KISS & KEYWORDS].
[Health Communication: Preventing the Spread of Ebola Virus Disease in the Portuguese Spoken African Countries - Methodology KISS & KEYWORDS]. Acta Med Port. 2015 Mar-Apr;28(2):141-4 Authors: De Santiago I, Miguel JP, Antunes F Abstract In this work, Health Communication is considered as an important discipline in medicine and health sciences for his role as true determinant of health. We highlight their contribution to health promotion and disease prevention. Thus, the Health Communication Plan (PCS): Preventing the spread of Ebola virus disease in the Portuguese Speaking Afr...
Source: Acta Medica Portuguesa - June 13, 2015 Category: Journals (General) Tags: Acta Med Port Source Type: research

Diabetes mellitus prevalence in tuberculosis patients and the background population in Guinea-Bissau: a disease burden study from the capital Bissau
Conclusions The prevalence of DM was low, also among TB patients. No association between DM and TB was found. (Source: Transactions of the Royal Society of Tropical Medicine and Hygiene)
Source: Transactions of the Royal Society of Tropical Medicine and Hygiene - May 20, 2015 Category: Tropical Medicine Authors: Haraldsdottir, T. L., Rudolf, F., Bjerregaard-Andersen, M., Carlos Joaquim, L., Stochholm, K., Gomes, V. F., Beck-Nielsen, H., Ostergaard, L., Aaby, P., Wejse, C. Tags: ORIGINAL ARTICLES Source Type: research

Neonatal vitamin A supplementation associated with increased atopy in girls
ConclusionThe study corroborated previous observations; NVAS was associated with increased risk of atopy and wheezing, in this study only among females. Further studies on NVAS and atopy are warranted.This article is protected by copyright. All rights reserved. (Source: Allergy)
Source: Allergy - May 2, 2015 Category: Allergy & Immunology Authors: Sofie Aage, Nicholas Kiraly, Kassarai Da Costa, Stine Byberg, Morten Bjerregaard‐Andersen, Ane B. Fisker, Peter Aaby, Christine S. Benn Tags: Original Article: Epidemiology and Genetics Source Type: research

Feeding ecology of chimpanzees (Pan troglodytes verus) inhabiting a forest‐mangrove‐savanna‐agricultural matrix at Caiquene‐Cadique, Cantanhez National Park, Guinea‐Bissau
With rising conversion of “natural” habitat to other land use such as agriculture, nonhuman primates are increasingly exploiting areas influenced by people and their activities. Despite the conservation importance of understanding the ways in which primates modify their behavior to human pressures, data are lacking, even for well‐studied species. Using systematically collected data (fecal samples, feeding traces, and direct observations), we examined the diet and feeding strategies of an unhabituated chimpanzee community (Pan troglodytes verus) at Caiquene‐Cadique in Guinea‐Bissau that inhabit a forest‐savanna...
Source: American Journal of Primatology - March 20, 2015 Category: Psychiatry & Psychology Authors: Joana Bessa, Cláudia Sousa, Kimberley J. Hockings Tags: Research Article Source Type: research

High level of HIV-1 drug resistance among patients with HIV-1 and HIV-1/2 dual infections in Guinea-Bissau
Conclusions: Our results showed that patients with HIV-1 and HIV-1/2 dual infections in Guinea-Bissau had a high rate of virological failure and rapid development of NNRTI resistance. It remains to be determined whether a more robust, PI-based treatment regimen might benefit this population more than NNRTIs. (Source: Virology Journal)
Source: Virology Journal - March 11, 2015 Category: Virology Authors: Sanne JespersenMartin TolstrupBo HøngeCandida MedinaDavid TéSvend Ellermann-EriksenLars ØstergaardChristian WejseAlex Laursenfor The Bissau HIV cohort study group Source Type: research

Heterologous Immunological Effects of Early BCG Vaccination in Low-Birth-Weight Infants in Guinea-Bissau: A Randomized-controlled Trial
Conclusion. Four weeks after immunization, BCG-vaccinated infants have a significantly increased production of cytokines upon heterologous challenge, particularly T helper cell type 1 polarizing and typically monocyte-derived pro-inflammatory cytokines. BCG may accelerate the development of the neonatal immune system, mediating comprehensive protection against infections and mortality. (Source: The Journal of Infectious Diseases)
Source: The Journal of Infectious Diseases - February 23, 2015 Category: Infectious Diseases Authors: Jensen, K. J., Larsen, N., Biering-Sorensen, S., Andersen, A., Eriksen, H. B., Monteiro, I., Hougaard, D., Aaby, P., Netea, M. G., Flanagan, K. L., Benn, C. S. Tags: PATHOGENESIS AND HOST RESPONSE Source Type: research

Interobserver Variation of the Rapid Test SD Bioline HIV-1/2 3.0 for HIV Type Discrimination: Experiences From Guinea-Bissau
No abstract available (Source: JAIDS Journal of Acquired Immune Deficiency Syndromes)
Source: JAIDS Journal of Acquired Immune Deficiency Syndromes - January 16, 2015 Category: Infectious Diseases Tags: Letters to the Editor Source Type: research

A case of imported neurocysticercosis in Portugal
We report the case of a 24-year-old woman born and residing in Guinea-Bissau, who was transferred to Portugal two months after the onset of a possible meningitis (fever, headache, seizures, and coma) that did not respond to antibiotic treatment. The diagnosis of NCC was confirmed by MR imaging, which showed multiple lesions compatible with cysticercus, and by polymerase chain reaction (PCR) of the cerebrospinal fluid. After 28 days on albendazole and dexamethasone without improvement, she was started on praziquantel, which she completed in six weeks with progressive recovery. (Source: The Journal of Infection in Developing Countries)
Source: The Journal of Infection in Developing Countries - January 15, 2015 Category: Infectious Diseases Source Type: research

Water bags as a potential vehicle for transmitting disease in a West African capital, Bissau
Conclusion Findings showed that all packaged water samples were unfit for human consumption and during the 2012 cholera outbreak represented a potential vehicle for the spread of the disease. The design of measures to decrease the risk associated to the consumption of highly contaminated chilled water is clearly required. (Source: International Health)
Source: International Health - January 9, 2015 Category: Global & Universal Authors: Bordalo, A. A., Machado, A. Tags: ORIGINAL ARTICLES Source Type: research

Prevalence of community-acquired bacteraemia in Guinea-Bissau: an observational study
Conclusions: Bacteraemia was common irrespective of the presence of fever among children presenting to the hospital. The high prevalence of Staphylococcus aureus may be due to contamination. There is an imminent need to improve microbiological diagnostic facilities and to identify algorithms that can identify children at risk of bloodstream infections in Africa. (Source: BMC Infectious Diseases)
Source: BMC Infectious Diseases - December 20, 2014 Category: Infectious Diseases Authors: Joakim IsendahlCristovão ManjubaAmabelia RodriguesWeiping XuBirgitta Henriques-NormarkChristian GiskePontus Nauclér Source Type: research