Nocardia farcinica meningitis in a patient with high-grade astrocytoma
We describe a case of 91-year-old male with astrocytoma who developed meningitis caused byNocardia farcinica. He had a past medical history of anaplastic astrocytoma grade III. Endocranial computed tomography (CT) scan revealed mass lesion in the left occipital region associated with perilesional edema, without evidence of midline shift issue. The analyses of cerebrospinal fluid (CSF) revealed neutrophilic pleocytosis, hyperproteinorrachia and hypoglycorrhachia. Combined antimicrobial therapy was initiated (vancomycin, meropenem, acyclovir). CSF culture revealedNocardia farcinica. Susceptibility testing revealed intermedia...
Source: The Journal of Infection in Developing Countries - September 30, 2019 Category: Infectious Diseases Source Type: research

Extended Spectrum Beta-lactamase producing Salmonella Lindenberg gastroenteritis
Conclusion: Presently, there are no Indian reports on theblaSHV positive ESBL producing S. Lindenberggastroenteritis. We report on the successful management of the first case of acute gastroenteritis caused byS. Lindenbergthat exhibited dual resistance to fluoroquinolone and third generation cephalosporins. Continued surveillance of the antibiotic resistance pattern of the Non-typhoidalSalmonellaserovars circulating in the geographical region is warranted. (Source: The Journal of Infection in Developing Countries)
Source: The Journal of Infection in Developing Countries - September 30, 2019 Category: Infectious Diseases Source Type: research

Levels of different cytokines in women and men with asymptomatic genital infection caused by Chlamydia
Conclusions: Our results demonstrated that no signi ficant difference in cytokine concentrations exists inChlamydia trachomatisinfected patients when compared to healthy controls. In further study, we aim to test on a greater number of positive samples a greater number of cytokines involved in the immune response toChlamydia trachomatis infections. (Source: The Journal of Infection in Developing Countries)
Source: The Journal of Infection in Developing Countries - September 30, 2019 Category: Infectious Diseases Source Type: research

High seroprevalence of pathogenic Yersinia spp. in sheep and goats across nine government farms in the Pakistani Punjab
Conclusion: Due to the high number of the population involved in raising small ruminants the risk to veterinary and public health must be rapidly determined. (Source: The Journal of Infection in Developing Countries)
Source: The Journal of Infection in Developing Countries - September 30, 2019 Category: Infectious Diseases Source Type: research

First detection of vanB phenotype-vanA genotype vancomycin-resistant enterococci in Egypt
Conclusion; VanB phenotype-vanAgenotype was identified in (33.3%) of vancomycin resistant enterococcal isolates. To our knowledge it is the first identified incidence of such strains in Egypt and Africa. (Source: The Journal of Infection in Developing Countries)
Source: The Journal of Infection in Developing Countries - September 30, 2019 Category: Infectious Diseases Source Type: research

First report on seroprevalence and risk factors of Toxoplasma gondii infection in sheep and goats in North Lebanon
Introduction: Toxoplasmosis is of dual importance in both public and veterinary health due to the respective risk of transplacental transmission in primo-infected pregnant women and economic losses caused by abortions in mammals. One of the main routes ofToxoplasma gondii transmission to humans is the consumption of raw or undercooked meats containing parasitic cysts. Here, we performed the first epidemiological study to determine the seroprevalence and the risk factors of toxoplasmosis in livestock in Lebanon.Methodology: Using a modified agglutination test with a cut-off of 1:40, we tested the positivity rate of Immunogl...
Source: The Journal of Infection in Developing Countries - September 30, 2019 Category: Infectious Diseases Source Type: research

Comparison of the clinical and laboratory characteristics of pertussis or viral lower respiratory tract infections
Introduction: Whooping cough-like respiratory tract infections (WCLRTI) caused by factors other than theBordetella pertussis are available. Clinical picture is difficult to differentiate between theB. pertussisand viral respiratory infections.Methodology: Eighty-five patients with the diagnosis of WCLRTI were divided into 3 groups. Group 1 involved patients with pertussis shown by nasopharyngeal aspirate culture (NAC) and/or PCR. Group 2 consisted of patients who B. pertussis was not detected by NAC however, clinicians still evaluated them as potential patients of pertussis. Group 3 involved patients with the diagnosis of ...
Source: The Journal of Infection in Developing Countries - September 30, 2019 Category: Infectious Diseases Source Type: research

Endocan serum concentration in uninfected newborn infants
Conclusions: ESC (ng/mL) between the first and third day of life in either term or preterm infants don ’t appear to be significantly influenced by factors that are associated with elevation of inflammatory markers, thus using this biomarker for the diagnosis of EOS might reduce the false positive results. (Source: The Journal of Infection in Developing Countries)
Source: The Journal of Infection in Developing Countries - September 30, 2019 Category: Infectious Diseases Source Type: research

High rate of neonates colonized by methicillin-resistant Staphylococcus species in an Intensive Care Unit
Conclusion: High rate of neonates colonized by methicillin-resistantStaphylococcus species and the permanence of clones circulating in the NICU highlight the importance for continuous and preventive surveillance in this high-risk population. (Source: The Journal of Infection in Developing Countries)
Source: The Journal of Infection in Developing Countries - September 30, 2019 Category: Infectious Diseases Source Type: research

Antimicrobial resistance and molecular characterization of Streptococcus agalactiae from pregnant women in southern China
Conclusions: The high level of resistance conferred by some corresponding resistance genes to macrolides, lincosamides and quinolones of GBS isolates from pregnant women in southern China, has reinforced the necessity for monitoring GBS strain resistance to the above agents. Comparative genetic studies of GBS isolates, especially efforts to understand the relationship between pilus islands and genotype, were essential for conducting infection control and epidemiological comparisons between countries. (Source: The Journal of Infection in Developing Countries)
Source: The Journal of Infection in Developing Countries - September 30, 2019 Category: Infectious Diseases Source Type: research

High prevalence of TEM, VIM, and OXA-2 beta-lactamases and clonal diversity among Acinetobacter baumannii isolates in Turkey
Conclusions: The most prevalent OXA genes wereblaOXA-51,blaOXA-23, andblaOXA-2. Furthermore,blaTEM,blaSHV, andblaVIM, which are common in Enterobacterales andPseudomonasspp, were detected, suggesting horizontal gene transfer had occurred between bacteria. No single clone outbreak was detected by PFGE. However, multiclonal spread and the high clustering rate suggest cross-contamination. Therefore, in future, more effective infection control measures must be implemented. (Source: The Journal of Infection in Developing Countries)
Source: The Journal of Infection in Developing Countries - September 30, 2019 Category: Infectious Diseases Source Type: research

Pathological and clinical investigations of an outbreak of Blackleg disease due to C. chauvoei in cattle in Punjab, Pakistan
Introduction: Clostridium chauvoei(C. chauvoei) is an anaerobic, histotoxic Gram-positive, bacterium causing fatal myonecrosis in livestock with high mortalities. The disease is common in dairy animals, but little is known about the pathophysiology of the disease in exotic (non-native) animals kept under local conditions in Pakistan.Methodology: Diagnosis of blackleg was made based on hematological and serum biochemical analysis, PCR, necropsy and histopathology.Results: Clinically sick animals exhibited fever, lameness, subcutaneous gaseous swelling and edema particularly in hindquarter and front legs. Hematological analy...
Source: The Journal of Infection in Developing Countries - September 30, 2019 Category: Infectious Diseases Source Type: research

Genetic diversity and biofilm formation analysis of Staphylococcus aureus causing urinary tract infections in Tehran, Iran
Conclusion: Biofilm encoding genesicaDandspatype t790 and agrtype III were the most prevalent factors among MDR biofilm producer isolates. The study emphasized that identification of genes and characterization of molecular types involved in biofilm formation should be considered. (Source: The Journal of Infection in Developing Countries)
Source: The Journal of Infection in Developing Countries - September 30, 2019 Category: Infectious Diseases Source Type: research

Emergence of mcr-1 mediated colistin resistant Escherichia coli from a hospitalized patient in Bangladesh
Conclusions: This is the first human associatedmcr in Bangladesh. These data indicate the need for a systematic “one health” surveillance in the country. (Source: The Journal of Infection in Developing Countries)
Source: The Journal of Infection in Developing Countries - August 31, 2019 Category: Infectious Diseases Source Type: research

Diagnosis of human sporotrichosis in Campos dos Goytacazes, Rio de Janeiro, Brazil
Conclusion: In recent years, sporotrichosis has been diagnosed with relative frequency in Campos dos Goytacazes, causing great concern among public health officials and practitioners. (Source: The Journal of Infection in Developing Countries)
Source: The Journal of Infection in Developing Countries - August 31, 2019 Category: Infectious Diseases Source Type: research

Prevalence of Epstein-Barr virus DNA in tonsillar tissue from patients with chronic tonsillitis in Mexican population
Conclusions: The prevalence found of EBV-DNA positivity in tonsillar tissues from patients diagnosed with chronic tonsillitis , supports the fact that palatine tonsils can be occupied by EBV and highlights the importance of conducting future studies focused on understanding the role of the EBV infection in chronic inflammatory processes in the population involved in this study. (Source: The Journal of Infection in Developing Countries)
Source: The Journal of Infection in Developing Countries - August 31, 2019 Category: Infectious Diseases Source Type: research

Abnormalities in electrocardiographic ventricular repolarization in patients with dengue virus infection
Conclusions: Myocardial repolarization changes do occur in patients with DENV. Having into account the potential impact of these changes on patients ’ outcome, and because 12-lead ECG is not routinely recommended in the setting of DENV in our country, we recommend that a 12-lead ECG be taken from each patient with this condition during DENV epidemics. (Source: The Journal of Infection in Developing Countries)
Source: The Journal of Infection in Developing Countries - August 31, 2019 Category: Infectious Diseases Source Type: research

Molecular epidemiological of extended-spectrum β-lactamase producing Escherichia coli isolated in Djibouti
Conclusions: There is no major difference with African epidemiology. In particular, we notice the international diffusion of specific clonal group ST131. (Source: The Journal of Infection in Developing Countries)
Source: The Journal of Infection in Developing Countries - August 31, 2019 Category: Infectious Diseases Source Type: research

Antimicrobial stewardship approach: Prevalence of antimicrobial resistant bacteria at a regional hospital in South Africa
Conclusion: The selection of empirical antimicrobial therapy relates not only the institutions or unit-specific antibiogram but also the site of infection. We can further suggest continuing to do surveillance of antibiogram and prevalence of MDR organisms for infection control as well as for empirical therapy, part of the antimicrobial stewardship program based on yearly records to change the local hospital antibiotic policy. (Source: The Journal of Infection in Developing Countries)
Source: The Journal of Infection in Developing Countries - August 31, 2019 Category: Infectious Diseases Source Type: research

Hand hygiene knowledge, perception and practice of healthcare workers in a Turkish university hospital intensive care unit
Conclusions: Despite regular HH trainings, healthcare workers could not differentiate when HH was not required which suggested failure to understand HH rationale. This may explain poor HH compliance rates. A systematic study is needed in order to find out the reasons behind of this noncompliance and improve HH training methods for educating healthcare workers. (Source: The Journal of Infection in Developing Countries)
Source: The Journal of Infection in Developing Countries - August 31, 2019 Category: Infectious Diseases Source Type: research

Evaluation of biochemical, hematological, RIBA and PCR assays in predicting viremia in anti-HCV positive patients
Introduction: The detection of HCV-RNA by PCR assays is considered to be the gold standard for confirming the presence of HCV viremia. However, high costs, long and laborious procedures limit their widespread usage. This retrospective study was conducted to assess the predictive performances of biochemical and hematological parameters, anti-HCV signal-to-cutoff (S/CO) ratios and RIBA assay for HCV viremia.Methodology: Medical records of 210 patients with positive anti-HCV results were analyzed. Samples were tested for anti-HCV by the Roche Elecsys assay. RIBA and PCR assays were performed with Inno-Lia HCV Score test, and ...
Source: The Journal of Infection in Developing Countries - August 31, 2019 Category: Infectious Diseases Source Type: research

Epidemiology and mortality in bacterial bloodstream infections in patients with hematologic malignancies
Conclusions: In patients with hematological malignancies, certain factors in the bloodstream infections increase the mortality rate. With the correction of these factors, the mortality rate in these patients can be reduced. The classification of such risk factors may be an important strategy to improve clinical decision making in high-risk patients, such as patients with hematological malignancies. (Source: The Journal of Infection in Developing Countries)
Source: The Journal of Infection in Developing Countries - August 31, 2019 Category: Infectious Diseases Source Type: research

Helicobacter pylori culture as a key tool for diagnosis in Colombia
Conclusions: We present evidence that RUT and histological methods will be better interpreted for diagnosis ofH. pylori if combined with bacterial isolation in cholesterol enriched culture. (Source: The Journal of Infection in Developing Countries)
Source: The Journal of Infection in Developing Countries - August 31, 2019 Category: Infectious Diseases Source Type: research

Serum levels of soluble CD163 and soluble CD14 following antibiotic therapy of patients with acute brucellosis
Introduction: Soluble CD163 (sCD163) and soluble CD14 (sCD14) levels, monocyte/macrophage activation markers, are elevated in patient serum during Brucellainfection. The aim of this study was to measure serum sCD163 and sCD14 levels during treatment for acute brucellosis to determine whether they can be used to monitor treatment efficacy.Methodology: Blood samples were collected from 30 patients with acute brucellosis (disease duration
Source: The Journal of Infection in Developing Countries - August 31, 2019 Category: Infectious Diseases Source Type: research

Comparison of clinical and pathological features of lymph node tuberculosis and histiocytic necrotizing lymphadenitis
This study selected 85 cases of lymph node tuberculosis (Group A patients) and 26 cases of histiocytic necrotizing lymphadenitis (Group B patients). The clinical and pathology features on both groups were analysed.Results: The Group A patients were older than the Group B patients (t = 5.233,P
Source: The Journal of Infection in Developing Countries - August 31, 2019 Category: Infectious Diseases Source Type: research

Antibiotic resistance and biofilm formation in children with Enteropathogenic Escherichia coli (EPEC) in Brazilian Amazon
Conclusion: Based on our findings, there was increased aEPEC identification. EPEC isolates showed high resistance rate; most strains showed multiresistance; thus, they work as warning about the continuous need of surveillance towards antimicrobial use. Besides, the ability of forming biofilm was evidenced by the EPEC isolates. This outcome is worrisome, since it is a natural resistance mechanism of bacteria. (Source: The Journal of Infection in Developing Countries)
Source: The Journal of Infection in Developing Countries - August 31, 2019 Category: Infectious Diseases Source Type: research

A multicenter study of β-lactamase-producing Klebsiella pneumoniae isolated from university teaching hospitals of Urmia, Iran
Conclusions: A relatively high prevalence of β-lactamase genes was seen among multidrug-resistant isolates ofK. pneumoniae. Most patients infected with β-lactamase-producing isolates had a history of long-term hospitalization and nosocomial infections. The predominance of β-lactamase genes in intensive care unit and internal units alarm clinicians to the growth of hospitalization and mortality rates. (Source: The Journal of Infection in Developing Countries)
Source: The Journal of Infection in Developing Countries - August 31, 2019 Category: Infectious Diseases Source Type: research

Self-Medication with Antibiotics among University Students in LMIC: A systematic review and meta-analysis
Conclusions: The practice of SMA is a widespread phenomenon among university students in LMICs and is frequently associated with inappropriate use. Effective interventions such as medication education and stricter governmental regulation concerning antibiotic use and sale are required to be established in order to deal with SMA properly. (Source: The Journal of Infection in Developing Countries)
Source: The Journal of Infection in Developing Countries - August 31, 2019 Category: Infectious Diseases Source Type: research

Antimicrobial resistance and virulence associated genes in Campylobacter jejuni isolated from chicken in C ôte d’Ivoire
Conclusion: Because of the key role of broiler chicken in human campylobacteriosis infection, it will important in first time to monitoring using of antibiotics in chicken farms and in second time to verify presence of campylobact ériosis in country. (Source: The Journal of Infection in Developing Countries)
Source: The Journal of Infection in Developing Countries - August 31, 2019 Category: Infectious Diseases Source Type: research

Adenovirus 36 and its effect on vitamin D levels in obese and overweight patients
Introduction: The aim of this study was to investigate the prevalence of Adenovirus-36 (Ad-36) in overweight and obese patients and the effects of this virus on some metabolic parameters.Methodology: The study included 236 female patients with body mass index (BMI) ≥ 25. The patients were separated into 2 groups as overweight (BMI: 25-29.99) and obese (BMI ≥ 30). To quantitatively determine the antibody (Ab) specific to adenovirus type 36 in the serum samples, the enzyme-immunoassay (EIA) method was used (AdV36-Ab, ELISA Kit, MyBioSource).Laboratoryparameters were compared between patients who are Ad-36 Ab positive a...
Source: The Journal of Infection in Developing Countries - July 31, 2019 Category: Infectious Diseases Source Type: research

Awareness, knowledge, and practice for hepatitis B infection in Southeast Asia: a cross-sectional study
We examined the awareness of, knowledge about, practices and views on treatment for HBV infection in Southeast Asia. A cross-sectional survey was conducted from December 2016 to February 2017 among individuals from six nations in Southeast Asia —Myanmar, Thailand, Vietnam, Cambodia, the Philippines, and Singapore. The study population comprised healthcare and non-healthcare personnel.Results: In total, 799 healthcare personnel and 1079 non-healthcare personnel completed an online survey. The prevalence of the awareness of their own HBV infection status and risk of this regionally endemic infection was 85.6% (684/799)...
Source: The Journal of Infection in Developing Countries - July 31, 2019 Category: Infectious Diseases Source Type: research

A prospective pharmacovigilance study in the infectious diseases unit of a tertiary care hospital
Introduction: The frequency, causality, severity, preventability and risk factors of ADRs (adverse drug reactions) in infectious disease units are not well defined in the literature. Thus, the aim of this study was to determine the characteristics of the ADRs encountered in an infectious disease unit of a tertiary teaching hospital.Methodology: The patients who were admitted to the infectious disease unit of a tertiary teaching hospital longer than 24 hours between January and December of 2016 were followed prospectively. Patients were observed and questioned for any sign of ADRs. The proportion of ADRs and patient charact...
Source: The Journal of Infection in Developing Countries - July 31, 2019 Category: Infectious Diseases Source Type: research

A simple STAR Element Repetitive-PCR (SER-PCR) typing method for the rapid characterization of Staphylococcus aureus
Conclusions: This study provides a simple genotyping method forS. aureus based on the variation of the amplicon size of a single set of primers and rapidly extracted DNA. The method is rapid with acceptable discriminatory power and does not require a sophisticated apparatus or special expertise. The results suggest that SER-PCR could be routinely useful in any clinical microbiology laboratory, particularly in developing countries. (Source: The Journal of Infection in Developing Countries)
Source: The Journal of Infection in Developing Countries - July 31, 2019 Category: Infectious Diseases Source Type: research

The Antibiotic sensitivity of Stenotrophomonas maltophilia in a 5-year period and investigation of clonal outbreak with PFGE
Conclusions: There was a clonal relationship between the vast majority of the 35S. maltophilia isolates, which suggests that there was a cross-contamination problem in the hospital. One strain (#4) was identified by dendrogram analysis showed a high rate of similarity to the other strains and was determined to be the common source of the cross-contamination. (Source: The Journal of Infection in Developing Countries)
Source: The Journal of Infection in Developing Countries - July 31, 2019 Category: Infectious Diseases Source Type: research

Biocide susceptibilities and biofilm-forming capacities of Acinetobacter baumannii clinical isolates from Malaysia
Conclusion. The TerengganuA. baumannii isolates showed higher prevalence ofqacDE1 compared toqacE although no correlation was found with the biocides ’ MIC values. No correlation was also observed between the isolates’ biofilm-forming capacity and the MIC values for the biocides. (Source: The Journal of Infection in Developing Countries)
Source: The Journal of Infection in Developing Countries - July 31, 2019 Category: Infectious Diseases Source Type: research

Predominance of Central Asian strain (ST 26) in Mycobacterium tuberculosis isolates from Balochistan by spoligotyping
Conclusions: This is the first insight into the genotype ofM. tuberculosis strains in the Balochistan region that might serve as a base line study for control of tuberculosis in the community. (Source: The Journal of Infection in Developing Countries)
Source: The Journal of Infection in Developing Countries - July 31, 2019 Category: Infectious Diseases Source Type: research

Non-tuberculous mycobacteria profiles and their anti-mycobacterial resistance at a major medical center in Lebanon
Conclusion: The revelaed different NTM species, with predominance ofM.simiaeand various AMR profiles provide a current epidemiologic database and help guiding the selection of appropriate empirical therapy once the clinical relevance is established. (Source: The Journal of Infection in Developing Countries)
Source: The Journal of Infection in Developing Countries - July 31, 2019 Category: Infectious Diseases Source Type: research

Multidrug-resistant Gram-negative bacilli sepsis from a neonatal intensive care unit: a case-case-control study
Introduction: To identify the risks and outcomes for multidrug-resistant Gram-negative bacilli (MDRGNB) sepsis in neonates.Methodology: This was a retrospective case-case-control study between 1991 and 2016. The control group was selected from the same source records of all neonates with clinical or suspected sepsis but not culture-proven.Results: The numbers of patients in the MDRGNB sepsis, non-MDRGNB sepsis, and control groups were 157, 88, and 218, respectively. MDRGNB sepsis was significantly associated with outborn infants [adjusted odds ratio (aOR) 2.08; p = 0.003] and infants who had a neurologic sequela (aOR 11.58...
Source: The Journal of Infection in Developing Countries - July 31, 2019 Category: Infectious Diseases Source Type: research

Performance of a new in-house medium Carba MTL-broth for the rapid detection of carbapenemase-producing Enterobacteriaceae
Conclusions: The in-house Carba MTL-broth developed in this study is sensitive, inexpensive, an easy-to-use phenotypic method for the detection of OXA-48-producing enterobacteria. Given the burden of pan-drug resistance, its implementation in the microbiology laboratory of developing countries could be a useful tool for rapid detection of these bacteria. (Source: The Journal of Infection in Developing Countries)
Source: The Journal of Infection in Developing Countries - July 31, 2019 Category: Infectious Diseases Source Type: research

Physicians ’ knowledge, attitudes and practices towards Zika virus infection in Jordan
Conclusions: General physicians and gynecologists in Jordan had several gaps in knowledge of key aspects of ZIKAV disease, and there is a need for specific training programs of physicians and gynecologists. (Source: The Journal of Infection in Developing Countries)
Source: The Journal of Infection in Developing Countries - July 31, 2019 Category: Infectious Diseases Source Type: research

Engaging people who inject drugs and their peers in HIV testing and harm reduction in Ukraine: do they make a difference?
Introduction: People Who Inject Drugs (PWID) should be offered HIV-testing and harm reduction services. We assessed the effectiveness of including PWID and their peers in HIV-testing by comparing for a period before (2013-2014) and after their introduction (2015-2017), the a) numbers HIV tested b) number enrolled in harm reduction and c) frequency of HIV-testing.Methodology: An analysis of programme data involved PWID aged ≥ 14 years (1st January 2013-31st December 2017) in Ukraine. Between 2013-2014, HIV-testing (VCT) was done by trained health workers. From 2015, this was Directly Assisted HIV Self-testing (DAST) done...
Source: The Journal of Infection in Developing Countries - July 31, 2019 Category: Infectious Diseases Source Type: research

Anxiety, depression, and quality of life among HIV positive injection drug users in Ukraine, 2017
Conclusion: There are increased depressive and anxiety symptoms and poorer QoL among HIV-positive PWID in Ukraine. Strategies focusing on psychosocial support addressing QoL as part of HIV care could improve health outcomes for these comorbid and debilitating conditions. (Source: The Journal of Infection in Developing Countries)
Source: The Journal of Infection in Developing Countries - July 31, 2019 Category: Infectious Diseases Source Type: research

People with high HIV viral load within risk networks: who are these people and who refers them best?
Introduction: Viral load is one of the most important determinants for HIV transmission. Identification of people with high viral load (PHVL) can be effective in limiting onward HIV transmission. In order to improve the identification of these individuals within risk networks, we determined a) the number of PHVL recruited through risk networks b) their socio-demographic, behavioural and clinical characteristics and c) the characteristics of individuals who referred these PHVL to the study.Methodology: From November 2013 to March 2016, in Odessa, Ukraine, Transmission Reduction Intervention Project (TRIP) was implemented to...
Source: The Journal of Infection in Developing Countries - July 31, 2019 Category: Infectious Diseases Source Type: research

Linking intravenous drug users to treatment through non-governmental organizations in Ukraine: how well is it working?
Introduction: Alliance for Public Health, the International Charitable Foundation, coordinates HIV prevention in Non-Governmental Organizations (NGO) working with people who inject drugs (PWID) in Ukraine. We aimed to describe the performance of the differential model of linking PWID to HIV care and treatment (Community Initiated Treatment Intervention – CITI).Methodology: A retrospective cohort study using routine program data was conducted among 8,927 PWID who were tested positive for the first time during January 2016 – June 2017. Study outcomes were enrollment into CITI and initiating antiretroviral treatme...
Source: The Journal of Infection in Developing Countries - July 31, 2019 Category: Infectious Diseases Source Type: research

Strategies for active detection of tuberculosis in Ukraine: Comparative effectiveness amongst key populations (2014-2018)
Conclusions: The active case finding in KPs increased detection of TB cases in Ukraine, and the majority of diagnosed KPs initiated TB treatment. Centralization of diagnosis reduced the effectiveness of TB screening. Each region in Ukraine should assess the composition and the needs of KPs which will allow for adoption of specific strategies to detect TB among KPs with high TB prevalence. (Source: The Journal of Infection in Developing Countries)
Source: The Journal of Infection in Developing Countries - July 31, 2019 Category: Infectious Diseases Source Type: research

Primary healthcare centers engagement in tuberculosis treatment in Ukraine
Introduction: We assessed the influence of a result-based financing (RBF) model, which included incentives for Primary Healthcare facilities on TB treatment outcomes.Methodology: We compared TB patients> 17 years and their treatment outcomes among those who did and did not benefit from RBF-model in 14 districts of Odeska oblast, Ukraine in 2017. Log-binomial regression was used to examine factors associated with being included in RBF-model.Results: Of 2,269 reported TB patients, 308 (14%) were included in RBF-model. Most patients in the RBF-model were from rural areas 229 (74%), unemployed 218 (71%), and HIV-infected 13...
Source: The Journal of Infection in Developing Countries - July 31, 2019 Category: Infectious Diseases Source Type: research

Why a special issue of JIDC on tuberculosis and HIV among key populations in Ukraine?
. (Source: The Journal of Infection in Developing Countries)
Source: The Journal of Infection in Developing Countries - July 31, 2019 Category: Infectious Diseases Source Type: research

Retrospective multicenter study reveals absence of MRSA-associated bovine mastitis in Brazil (1994 to 2016)
(Source: The Journal of Infection in Developing Countries)
Source: The Journal of Infection in Developing Countries - June 30, 2019 Category: Infectious Diseases Source Type: research

A Extensively drug-resistant Pseudomonas putida bacteremia that was resolved spontaneously
Pseudomonas putida (P. putida)is a rare pathogen that causes various infections in newborns, neutropenic and cancer patients, or in patients with risk factors leading to immunosuppresion. Antibiotic resistance inP. putida is seen in growing numbers. Although it is less virulent compared toPseudomonas aeruginosa, mortal infections are reported.Here, aP. putida case after an invasive procedure in a patient with gastrointestinal malignancy is reported. Although, it caused an antibiotic resistant bacteremia, it resolved spontaneously without any treatment. P. Putidamight have lower virulence and a different antibiotic suscepti...
Source: The Journal of Infection in Developing Countries - June 30, 2019 Category: Infectious Diseases Source Type: research

The efficacy of new 2,5-dihydroxybenzyl derivatives against Trypanosoma cruzi, Leishmania infantum and Leishmania braziliensis
Conclusion: This evidence suggests that the anti-parasitic activity observed in these analogs is affected by the size of the group at the 4-position of the second ring, but not related with electronic factors.This study identified hit compounds with the potential to target several kinetoplastid parasites. (Source: The Journal of Infection in Developing Countries)
Source: The Journal of Infection in Developing Countries - June 30, 2019 Category: Infectious Diseases Source Type: research