Synergistic combination of aztreonam and ceftazidime/avibactam against resistant Stenotrophomonas maltophilia on pancreatitis
Conclusions: There are sparse data providing guidance on the optimal regimen against MDRS. maltophilia infections. Although in this case a surgical excision was essential, combination of ATM and CZA provided effective synergistic antimicrobial treatment with clinical cure of severe acute pancreatitis infected withS. maltophilia. The combined disk pre-diffusion test with ATM and CZA requires no special equipment and can be routinely performed in clinical microbiology labs. Combination of ATM with CZA should be considered for cases of MDRS. maltophilia infections with limited treatment options. (Source: The Journal of Infect...
Source: The Journal of Infection in Developing Countries - June 29, 2023 Category: Infectious Diseases Authors: Nat ália de Almeida Torres, Ronaldo Morales Junior, Luis Fernando Bueno Lopes, Rogério Zeigler, David Everson Uip Source Type: research

Prevalence of intestinal parasites during pre- and post-COVID-19 pandemic at a tertiary care center in Lebanon
Conclusions: These findings indicate an overall reduction in the prevalence of IPI during the post-covid period, though IPIs persistence remains high. This highlights the need for enhancing public health awareness efforts to improve hygiene and sanitation to reduce parasitic prevalence in Lebanon. (Source: The Journal of Infection in Developing Countries)
Source: The Journal of Infection in Developing Countries - June 29, 2023 Category: Infectious Diseases Authors: Hani El Achkar, Lina Ghandour, Sarah Farran, George F Araj Source Type: research

Angiotensin-converting enzyme 2 G8790A polymorphisms are associated with COVID-19 severity
Conclusions: The findings indicated that the G allele ofACE2 G8790A was related to an enhanced risk of COVID-19 severity in Asians. One possible reason is thatACE2 G allele was associated with a COVID-19 cytokine storm. Furthermore, Asians have higher levels ofACE2 transcripts than Caucasians and Africans. Therefore, a genetic factor should be considered when developing vaccines in the future. (Source: The Journal of Infection in Developing Countries)
Source: The Journal of Infection in Developing Countries - June 29, 2023 Category: Infectious Diseases Authors: Yan Pan Source Type: research

Outcome of COVID-19 and tolerance of Remdesivir in patients with renal failure: a single center experience from Pakistan
Conclusions: COVID-19 in renal failure has a high risk for ICU admissions leading to increased mortality. Multiple comorbidities and raised inflammatory markers are predictors of poor outcomes. We observed no significant drug-related adverse effects, and none of our patients required discontinuation of RDV due to worsening renal function. (Source: The Journal of Infection in Developing Countries)
Source: The Journal of Infection in Developing Countries - June 29, 2023 Category: Infectious Diseases Authors: Zaheer Udin Babar, Sunil Kumar Dodani, Asma Nasim, Jawahar Lal Langhani, Sanjay Kumar Badlani Source Type: research

A study of long COVID-19 in Duhok, Kurdistan region, Iraq
Conclusions: There was a significant correlation between long COVID-19 cases and age, gender, comorbidities, and duration of infection. The data of this report can be used as a baseline for studies that may help further understand long COVID-19 sequelae. (Source: The Journal of Infection in Developing Countries)
Source: The Journal of Infection in Developing Countries - June 29, 2023 Category: Infectious Diseases Authors: Salmas S Ahmed, Pawan I Adil, Narin A Rasheed, Nawfal R Hussein, Kuldeep Dhama Source Type: research

Relapse of Evans syndrome following BNT162b2 (Pfizer-BioNTech) COVID-19 vaccine: case report and literature review
Conclusions: Although it is unclear whether the relationship between COVID-19 vaccination and relapse of ES in our patient is coincidental or causal, it highlights the need for monitoring of serious outcomes following vaccination. (Source: The Journal of Infection in Developing Countries)
Source: The Journal of Infection in Developing Countries - June 29, 2023 Category: Infectious Diseases Authors: Mirjana Cvetkovi ć, Nikola Pantić, Marijana Virijević, Zlatko Pravdić, Nikica Sabljić, Mirjana Mitrović, Nada Suvajdžić-Vuković Source Type: research

The hospitalization rate and clinical characteristics of mucormycosis prior and during COVID-19 pandemic: A single-center study
Conclusions: In high-risk patients, especially diabetics, special care to avoid the development of mucormycosis must be taken into account in patients with SARS-COV-2 infection considered for treatment with corticosteroids. (Source: The Journal of Infection in Developing Countries)
Source: The Journal of Infection in Developing Countries - June 29, 2023 Category: Infectious Diseases Authors: Mehrdad Estakhr, Zahra Ghotbi, Mahtab Rostamihosseinkhani, Etrat Hooshmandi, Masoud Janipour, Vahid Reza Ostovan, Nima Fadakar, Hanieh Bazrafshan, Zahra Bahrami, Abbas Rahimi-Jaberi, Maryam Poursadeghfard, Masoumeh Nazeri, Pariya Kouhi, Peyman Petramfar, Source Type: research

The evaluation of the relationship between COVID-19 and autoimmune responses with a cross-sectional trial using medical records
Conclusions: The SARS-CoV-2 infection could act as a triggering factor for developing autoimmune and/or autoinflammatory dysregulation in genetically predisposed individuals. (Source: The Journal of Infection in Developing Countries)
Source: The Journal of Infection in Developing Countries - June 29, 2023 Category: Infectious Diseases Authors: Ebru Yilmaz, Salih K üçük Source Type: research

The use of antibiotic prophylaxis in patients undergoing urologic procedures in an academic hospital Surabaya: A retrospective study
Conclusions: The 3rd generation cephalosporins (ceftriaxone) are mostly used in urological procedures despite the low susceptibility against this antibiotic in culturedE coli,P. aeruginosa, andK. pneumonia. The aminoglycosides have relatively good activity and have been suggested in several guidelines for urologic procedures, such as prostate and urinary tract stone procedures. It is crucial to consider the incision site, type of procedure, and bacterial profile in the hospital to propose antibiotic prophylaxis guidelines. (Source: The Journal of Infection in Developing Countries)
Source: The Journal of Infection in Developing Countries - June 29, 2023 Category: Infectious Diseases Authors: Tri Pudy Asmarawati, Tarmono Djojodimedjo, Dimas Panca Andhika, Musofa Rusli, Mariyatul Qibtiyah, Bagus Aulia Mahdi, Dwiki Novendrianto, Okla Sekar Martani, Hari Paraton, Heiman Wertheim, Kuntaman Kuntaman Source Type: research

Pseudoresistance to permethrin in scabies
Reports of permethrin resistance ofSarcoptes scabiei var. hominis are emerging. We propose that this may be pseudoresistance. The resistance is due to inadequate counselling by physicians, incorrect treatment (insufficient quantity of permethrin; too short length of treatment), and poor adherence and compliance by patients. Other reasons include single application of permethrin, suggestion to apply the drug for 6-8 hours, failed application on subungual folds, irritant contact dermatitis, in particular on genitals, for which some patients stop the treatment, and unexplainable use of permethrin in post-scabies prurigo. Thus...
Source: The Journal of Infection in Developing Countries - May 30, 2023 Category: Infectious Diseases Authors: Stefano Veraldi, Rossana Schianchi, Martina Silvio, Italo Francesco Aromolo Source Type: research

Cryptococcal meningitis post-covid-19 infection: Immunomodulation, a double-edged sword
This article describes the case and extensively reviews cryptococcal disease post-COVID-19 literature, highlighting the risk from immunosuppressive treatment. (Source: The Journal of Infection in Developing Countries)
Source: The Journal of Infection in Developing Countries - May 30, 2023 Category: Infectious Diseases Authors: Hilal W Abdessamad, Michel Achkar, Amal Al Zoghbi, Mohamad Fleifel, Abdul Rahman Ousta, Ahmad Kassar, Nadia L Samaha, Rita Nemr, Anna Farra, Jacques E Mokhbat, Rola Husni Source Type: research

Severe acute respiratory syndrome coronavirus-2 antibody response after Moderna vaccine booster on healthcare providers
Conclusions: Heterologous Moderna vaccine booster effectively increases antibody response against SARS-CoV-2 variants and shows mild symptoms of COVID-19 infection. (Source: The Journal of Infection in Developing Countries)
Source: The Journal of Infection in Developing Countries - May 30, 2023 Category: Infectious Diseases Authors: Fanny Fachrucha, Dianiati Kusumo Sutoyo, Fariz Nurwidya, Sita Laksmi Andarini, Agus Dwi Susanto, Fathiyah Isbaniah, Diah Handayani, Faisal Yunus, Dicky Soehardiman, Jamal Zaini, Silvana Saputri, Prasenohadi Source Type: research

Risk factors for prolonged viral RNA shedding in patients with COVID-19; a nested case-control study
Conclusions: Our study design included controlling confounders. We showed a clear result associating predicting factors with prolonged NCT of SARS-CoV-2. D-dimer level and bacterial co-infection were considered as independent predictors of prolonged NCT. (Source: The Journal of Infection in Developing Countries)
Source: The Journal of Infection in Developing Countries - May 30, 2023 Category: Infectious Diseases Authors: Yasemin Nadir, Pinar Kiran Source Type: research

Pre- and post-COVID-19 antimicrobial resistance profile of bacterial pathogens, a comparative study in a tertiary hospital
Conclusions: During the COVID-19 pandemic, the AMR rates of restricted and noncommunity-used antimicrobials declined. However, there was an increase in AMR to antimicrobials used without medical prescription. Therefore, restriction on the sale of antimicrobial drugs by community pharmacies without a prescription, hospital antimicrobial stewardship and awareness about the dangers of extensive use of antibiotics are recommended. (Source: The Journal of Infection in Developing Countries)
Source: The Journal of Infection in Developing Countries - May 30, 2023 Category: Infectious Diseases Authors: Mohammed H Taleb, Abdelraouf A Elmanama, Alaa H Taleb, Mahmoud M Tawfick Source Type: research

A comprehensive analysis of systematically screened laboratory tests: based on a COVID-19 cohort
Conclusions: The indicators obtained through systematic screening have preferable differential diagnosis values. Compared with non-COVID-19 patients, the screened indicators indicated that COVID-19 patients had more severe inflammatory responses, organ damage, electrolyte and metabolism disturbance, and coagulation disorders. This screening approach could find valuable indicators from a large number of laboratory test indicators. (Source: The Journal of Infection in Developing Countries)
Source: The Journal of Infection in Developing Countries - May 30, 2023 Category: Infectious Diseases Authors: Lei Chen, Gaojing Qu, Guoxin Huang, Meiling Zhang, Junwen Chen, Dengru Wang, Ying Liu, Bin Pei Source Type: research