Factors associated with birthweight and adverse pregnancy outcomes among children in rural Guinea-Bissau - a prospective observational study
Low birthweight (LBW) is associated with higher mortality and morbidity, but there is limited data on the prevalence of LBW in rural Africa, where many births occur at home. The Bacillus Calmette-Gu érin (BCG) ... (Source: BMC Public Health)
Source: BMC Public Health - June 17, 2021 Category: Consumer Health News Authors: Alexander Dahl Stjernholm, Sanne Marie Thysen, Igualdino Da Silva Borges and Ane B ærent Fisker Tags: Research Source Type: research

Chronic political instability and HIV/AIDS response in Guinea-Bissau: a qualitative study
ConclusionsStakeholders from government, civil society, and donor organizations have recognized instability ’s effects as a barrier to mounting an effective local response to HIV/AIDS in Guinea-Bissau. To mitigate the effects of the country’s political instability on the health sector, concerted efforts should be made to strengthen the capacities of health officials within the Ministry of Health to sh ield them from the effects of the country’s political instability.Graphic abstract (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - May 11, 2021 Category: Infectious Diseases Source Type: research

The Epidemiology of Plasmodium falciparum Malaria in the Bijagos Islands of Guinea-Bissau
This study aimed to estimate the prevalence of Plasmodium falciparum on Bubaque, the most populous island of the country's remote Bijagos archipelago. A cross-sectional survey was performed at the start of the rainy season in August 2017. Participants were recruited using systematic random sampling in a two-stage stratified cluster design. Malaria parasitemia was detected using rapid diagnostic tests (RDTs) and quantitative PCR (qPCR). Data on housing, education, larval source management, socioeconomic status, anemia, and malaria preventive measures were collected. Multivariable logistic regression models were constructed ...
Source: Am J Trop Med Hyg - March 30, 2021 Category: Infectious Diseases Authors: David McGregor Eunice Texeira da Silva Lynn Grignard Adriana Goncalves Hristina Vasileva David Mabey Anna Last Source Type: research

The Epidemiology of Plasmodium falciparum Malaria in the Bijagos Islands of Guinea-Bissau
This study aimed to estimate the prevalence of Plasmodium falciparum on Bubaque, the most populous island of the country's remote Bijagos archipelago. A cross-sectional survey was performed at the start of the rainy season in August 2017. Participants were recruited using systematic random sampling in a two-stage stratified cluster design. Malaria parasitemia was detected using rapid diagnostic tests (RDTs) and quantitative PCR (qPCR). Data on housing, education, larval source management, socioeconomic status, anemia, and malaria preventive measures were collected. Multivariable logistic regression models were constructed ...
Source: The American Journal of Tropical Medicine and Hygiene - March 30, 2021 Category: Tropical Medicine Authors: David McGregor Eunice Texeira da Silva Lynn Grignard Adriana Goncalves Hristina Vasileva David Mabey Anna Last Source Type: research

The Epidemiology of Plasmodium falciparum Malaria in the Bijagos Islands of Guinea-Bissau
This study aimed to estimate the prevalence of Plasmodium falciparum on Bubaque, the most populous island of the country's remote Bijagos archipelago. A cross-sectional survey was performed at the start of the rainy season in August 2017. Participants were recruited using systematic random sampling in a two-stage stratified cluster design. Malaria parasitemia was detected using rapid diagnostic tests (RDTs) and quantitative PCR (qPCR). Data on housing, education, larval source management, socioeconomic status, anemia, and malaria preventive measures were collected. Multivariable logistic regression models were constructed ...
Source: Am J Trop Med Hyg - March 30, 2021 Category: Infectious Diseases Authors: David McGregor Eunice Texeira da Silva Lynn Grignard Adriana Goncalves Hristina Vasileva David Mabey Anna Last Source Type: research

The Epidemiology of Plasmodium falciparum Malaria in the Bijagos Islands of Guinea-Bissau
This study aimed to estimate the prevalence of Plasmodium falciparum on Bubaque, the most populous island of the country's remote Bijagos archipelago. A cross-sectional survey was performed at the start of the rainy season in August 2017. Participants were recruited using systematic random sampling in a two-stage stratified cluster design. Malaria parasitemia was detected using rapid diagnostic tests (RDTs) and quantitative PCR (qPCR). Data on housing, education, larval source management, socioeconomic status, anemia, and malaria preventive measures were collected. Multivariable logistic regression models were constructed ...
Source: The American Journal of Tropical Medicine and Hygiene - March 30, 2021 Category: Tropical Medicine Authors: David McGregor Eunice Texeira da Silva Lynn Grignard Adriana Goncalves Hristina Vasileva David Mabey Anna Last Source Type: research

Intestinal protozoan infections shape fecal bacterial microbiota in children from Guinea-Bissau
by Sebastian von Huth, Louise B. Thingholm, Poul-Erik Kofoed, Corinna Bang, Malte C. R ühlemann, Andre Franke, Uffe Holmskov Intestinal parasitic infections, caused by helminths and protozoa, are globally distributed and major causes of worldwide morbidity. The gut microbiota may modulate parasite virulence and host response upon infection. The complex interplay between parasites and the gut microbiota is poorly underst ood, partly due to sampling difficulties in remote areas with high parasite burden. In a large study of children in Guinea-Bissau, we found high prevalence of intestinal parasites. By sequencing of the 16...
Source: PLoS Neglected Tropical Diseases - March 3, 2021 Category: Tropical Medicine Authors: Sebastian von Huth Source Type: research

Life expectancy of HIV-infected patients followed at the largest hospital in Guinea-Bissau is one-fourth of life expectancy of the background population
ConclusionsLE was shown to be markedly lower among HIV-infected patients compared with the background population. While other settings have shown marked improvements in prognosis of HIV-infected patients in recent years, no improvement in Bissau was observed over time (9.8  years (95% CI 7.6–12.2) and 9.9 years (95% CI 7.6–12.1) for the periods 2005–2010 and 2014–2016, respectively). (Source: Infection)
Source: Infection - February 2, 2021 Category: Infectious Diseases Source Type: research

Plastic pollution threat in Africa: current status and implications for aquatic ecosystem health.
This study is a review of plastic pollution reports from the African aquatic environment with regard to causes, current status, toxicological implications and implications for ecosystem services. A total of 59 plastic pollution studies from 1987 to September 2020 were reviewed. They comprised 15 from North Africa (NA) (Algeria, Egypt, Morocco and Tunisia), six from East Africa (EA) (Ethiopia, Kenya, Tanzania and Uganda), 13 from West Africa (WA) (Ghana, Guinea-Bissau, Mauritania and Nigeria), and 25 studies from Southern Africa (SA) (South Africa). This shows that plastic pollution studies in Africa, according to the sub-r...
Source: Environmental Science and Pollution Research International - January 4, 2021 Category: Environmental Health Authors: Akindele EO, Alimba CG Tags: Environ Sci Pollut Res Int Source Type: research

Prevalence, risk factors and health consequences of soil-transmitted helminth infection on the Bijagos Islands, Guinea Bissau: A community-wide cross-sectional study
This study reveals a persistent reservoir of STH infection across the community, with high rates of anaemia and malnutrition, despite high-coverage of mebendazole mass-drug administration in pre-school children. This reflects the need for a new strategy to soil-transmitted helminth control, to reduce infections and ultimately eliminate transmission. (Source: PLoS Neglected Tropical Diseases)
Source: PLoS Neglected Tropical Diseases - December 16, 2020 Category: Tropical Medicine Authors: Olivia Farrant Source Type: research

Reduced Mortality After Oral Polio Vaccination and Increased Mortality After Diphtheria-Tetanus-Pertussis Vaccination in Children in a Low-Income Setting.
Abstract PURPOSE: The diphtheria-tetanus-pertussis vaccine (DTP) and oral polio vaccine (OPV) were introduced in children 3 of 5 months of age in 1981-1983 in Bandim, in the capital of Guinea-Bissau. Because DTP has been linked to deleterious nonspecific effects (NSEs) and OPV to beneficial NSEs, we followed up this cohort to 3 years of age and examined the effects of DTP with OPV on all-cause mortality and the interactions of DTP and OPV with the measles vaccine (MV). METHODS: DTP and OPV were offered at 3 monthly community weighing sessions. Vaccination groups were defined by the last vaccine rec...
Source: Clinical Therapeutics - December 2, 2020 Category: Drugs & Pharmacology Authors: Øland CB, Mogensen SW, Rodrigues A, Benn CS, Aaby P Tags: Clin Ther Source Type: research

IJERPH, Vol. 17, Pages 8937: Use of Digital Technology Among Adolescents Attending Schools in Bissau, Guinea-Bissau
This study aimed to describe and analyse adolescents’ access to and usage of digital technology in Guinea-Bissau and its implications. In June 2017, a survey with a locally adapted Planet Youth questionnaire was implemented in the capital, Bissau, whereby classes in 16 secondary schools were surveyed on a variety of issues. In total, 2039 randomly selected students participated; the survey included ten questions specifically on the access to and use of digital technology. Half of the respondents had access to desktop/laptops, and one-third used mobile internet daily; about two-thirds had an experience of soci...
Source: International Journal of Environmental Research and Public Health - December 1, 2020 Category: Environmental Health Authors: Geir Gunnlaugsson Thomas Andrew Whitehead Fatou N ’dure Baboudóttir Aladje Bald é Zeca Jandi Hamadou Boiro J ónína Einarsdóttir Tags: Article Source Type: research

A survey of knowledge, attitudes and practices regarding malaria and bed nets on Bubaque Island, Guinea-Bissau
Malaria remains a significant public health problem in Guinea-Bissau, West Africa. Government control measures include bed net distribution campaigns, however, local knowledge, attitudes and practices towards ... (Source: Malaria Journal)
Source: Malaria Journal - November 17, 2020 Category: Infectious Diseases Authors: Harry Hutchins, Grace Power, Thomas Ant, Eunice Teixeira da Silva, Adriana Goncalves, Amabelia Rodrigues, James Logan, David Mabey and Anna Last Tags: Research Source Type: research

Macaroni sign and carotid occlusion in Takayasu ’s arteritis
A 29-year-old female from Guinea-Bissau was referred for Rheumatology observation with a 3-year history of fatigue, myalgia, dizziness, headache and anterior chest pain. On physical examination, the right carotid artery (CA) pulse was extremely diminished and left CA pulse absent. Laboratory tests revealed a normocytic anaemia (Hb 10.5  g/dl) and elevated erythrocyte sedimentation rate (93 mm/h) and C-reactive protein (0.55 mg/dl). Ultrasound of the right common CA showed a homogeneous and mid-echogenic circumferential wall thickening compatible with the ‘macaroni sign’ (Fig. 1A). Ultrasound of the left common CA...
Source: Rheumatology - November 3, 2020 Category: Rheumatology Source Type: research

Delay in tuberculosis diagnosis and treatment in Bissau, Guinea-Bissau
Conclusions: There must be a greater focus on health systems, wich, as we see, in this population was the main cause of delay in starting treatment. (Source: European Respiratory Journal)
Source: European Respiratory Journal - October 28, 2020 Category: Respiratory Medicine Authors: Costa Da Silva, J. C., Marcelina Dos Santos, E., Mendes, D., Duarte, R. Tags: Tuberculosis Source Type: research