Digging for care-seeking behaviour among gold miners in the Guyana hinterland: a qualitative doer non-doer analysis of social and behavioural motivations for malaria testing and treatment
Although Guyana has made significant progress toward malaria control, limited access to malaria testing and treatment services threatens those gains. Mining activities create breeding environments for mosquito... (Source: Malaria Journal)
Source: Malaria Journal - July 6, 2020 Category: Infectious Diseases Authors: Shirley D. Yan, Jennifer Orkis, Saifra Khan Sohail, Sean Wilson, TrishAnn Davis and J. Douglas Storey Tags: Research Source Type: research

Fluorescent markers rhodamine B and uranine for Anopheles gambiae adults and matings
Marking mosquitoes is vital for mark-release-recapture and many laboratory studies, but their small size precludes the use of methods that are available for larger animals such as unique identifier tags and ra... (Source: Malaria Journal)
Source: Malaria Journal - July 6, 2020 Category: Infectious Diseases Authors: Erica I. Aviles, Rachel D. Rotenberry, C. Mathilda Collins, Ellen. M. Dotson and Mark Q. Benedict Tags: Research Source Type: research

Defining symptoms of malaria in India in an era of asymptomatic infections
Malaria is a major public health problem in India. Data from surveys totaling 3031 participants at three sites revealed a high proportion of asymptomatic infections, complicating diagnosis. The aim of this stu... (Source: Malaria Journal)
Source: Malaria Journal - July 6, 2020 Category: Infectious Diseases Authors: Anna Maria van Eijk, Asad S. Mannan, Steven A. Sullivan and Jane M. Carlton Tags: Research Source Type: research

Investigating selected host and parasite factors potentially impacting upon seasonal malaria chemoprevention in Bama, Burkina Faso
Since 2014, seasonal malaria chemoprevention (SMC) with amodiaquine –sulfadoxine–pyrimethamine (AQ–SP) has been implemented on a large scale during the high malaria transmission season in Burkina Faso. This pap... (Source: Malaria Journal)
Source: Malaria Journal - July 6, 2020 Category: Infectious Diseases Authors: Fabrice A. Som é, Thomas Bazié, Hanna Y. Ehrlich, Justin Goodwin, Aine Lehane, Catherine Neya, Kabré Zachari, Martina Wade, Jean-Marie Ouattara, Brian D. Foy, Roch K. Dabiré, Sunil Parikh and Jean-Bosco Ouédraogo Tags: Research Source Type: research

Haem oxygenase protects against thrombocytopaenia and malaria-associated lung injury
Malaria-triggered lung injury can occur in both severe and non-severe cases. Platelets may interact with parasitized erythrocytes, leukocytes and endothelium. These interactions can lead to microvessel obstruc... (Source: Malaria Journal)
Source: Malaria Journal - July 1, 2020 Category: Infectious Diseases Authors: Isaclaudia G. de Azevedo-Quintanilha, Isabel M. Medeiros-de-Moraes, Andr é C. Ferreira, Patrícia A. Reis, Adriana Vieira-de-Abreu, Robert A. Campbell, Andrew S. Weyrich, Patricia T. Bozza, Guy A. Zimmerman and Hugo C. Castro-Faria-Neto Tags: Research Source Type: research

In silico and in vivo anti-malarial investigation on 1-(heteroaryl)-2-((5-nitroheteroaryl)methylene) hydrazine derivatives
Resistance of Plasmodium falciparum against common anti-malarial drugs emphasizes the need of alternative and more effective drugs. Synthetic derivatives of 1-(heteroaryl)-2-((5-nitroheteroaryl)methylene) hydrazi... (Source: Malaria Journal)
Source: Malaria Journal - June 29, 2020 Category: Infectious Diseases Authors: Azar Tahghighi, Seyed-Mahdi Mohamadi-Zarch, Hamzeh Rahimi, Mahya Marashiyan, Naseh Maleki-Ravasan and Ali Eslamifar Tags: Research Source Type: research

Effectiveness of a health education intervention on the use of long-lasting insecticidal nets for the prevention of malaria in pregnant women of Pakistan: a quasi-experimental study
About one quarter of pregnant women in the population of Pakistan are using long-lasting insecticide-treated bed nets (LLINs) for prevention of malaria. Past research reported that adequate information and edu... (Source: Malaria Journal)
Source: Malaria Journal - June 29, 2020 Category: Infectious Diseases Authors: Ramesh Kumar, Midhat Farzeen, Assad Hafeez, Baseer Khan Achakzai, Muskan Vankwani, Manohar Lal, Rabia Iqbal and Ratana Somrongthong Tags: Research Source Type: research

Submicroscopic malaria infection is not associated with fever in cross-sectional studies in Malawi
This study evaluated whether participants... (Source: Malaria Journal)
Source: Malaria Journal - June 29, 2020 Category: Infectious Diseases Authors: Jimmy Vareta, Andrea G. Buchwald, Angelica Barrall, Lauren M. Cohee, Jenny A. Walldorf, Jenna E. Coalson, Karl Seydel, Alick Sixpence, Don P. Mathanga, Terrie E. Taylor and Miriam K. Laufer Tags: Research Source Type: research

Dynamics of anti-malarial antibodies in non-immune patients during and after a first and unique Plasmodium falciparum malaria episode
Malaria is a major travel medicine issue. Retrospective confirmation of a malaria episode diagnosed in an endemic area can have relevant implications in transfusional medicine in Europe, where blood donors are... (Source: Malaria Journal)
Source: Malaria Journal - June 26, 2020 Category: Infectious Diseases Authors: Zeno Bisoffi, Marco Bertoldi, Ronaldo Silva, Giulia Bertoli, Tamara Ursini, Stefania Marocco, Chiara Piubelli, Elena Pomari, Dora Buonfrate and Federico Gobbi Tags: Research Source Type: research

Presence of additional Plasmodium vivax malaria in Duffy negative individuals from Southwestern Nigeria
Malaria in sub-Saharan Africa (sSA) is thought to be mostly caused by Plasmodium falciparum. Recently, growing reports of cases due to Plasmodium ovale, Plasmodium malariae, and Plasmodium vivax have been increas... (Source: Malaria Journal)
Source: Malaria Journal - June 26, 2020 Category: Infectious Diseases Authors: Mary Aigbiremo Oboh, Upasana Shyamsunder Singh, Daouda Ndiaye, Aida Sadikh Badiane, Nazia Anwar Ali, Praveen Kumar Bharti and Aparup Das Tags: Research Source Type: research

Anopheles arabiensis and Anopheles funestus biting patterns in Dielmo, an area of low level exposure to malaria vectors
In Dielmo, Senegal, the widespread use of long-lasting insecticidal nets has decreased both the incidence of malaria and the density of the Anopheles population. However, persistent low-level malaria transmission... (Source: Malaria Journal)
Source: Malaria Journal - June 26, 2020 Category: Infectious Diseases Authors: Souleymane Doucoure, Omar Thiaw, Am élé N. Wotodjo, Charles Bouganali, Nafisatou Diagne, Philippe Parola and Cheikh Sokhna Tags: Research Source Type: research

Coverage of intermittent preventive treatment of malaria in pregnancy (IPTp) influences delivery outcomes among women with obstetric referrals at the district level in Ghana
The aim of the study was to determine the coverage of intermittent preventive treatment of malaria in pregnancy (IPTp) and its relationship with delivery outcomes among obstetric referral cases at the district... (Source: Malaria Journal)
Source: Malaria Journal - June 24, 2020 Category: Infectious Diseases Authors: Mary Amoakoh-Coleman, Daniel K. Arhinful, Kerstin Klipstein-Grobusch, Evelyn K. Ansah and Kwadwo A. Koram Tags: Research Source Type: research

Efficacy and safety of artesunate –amodiaquine and artemether–lumefantrine and prevalence of molecular markers associated with resistance, Guinea: an open-label two-arm randomised controlled trial
This study aimed to assess the efficacy and safety of artesunate –amodiaquine (ASAQ) and artemether–lumefantrine (AL) in the management o... (Source: Malaria Journal)
Source: Malaria Journal - June 24, 2020 Category: Infectious Diseases Authors: Abdoul Habib Beavogui, Alioune Camara, Alexandre Delamou, Mamadou Saliou Diallo, Abdoulaye Doumbouya, Karifa Kourouma, Patrice Bouedouno, Timoth ée Guilavogui, Samaly dos Santos Souza, Julia Kelley, Eldin Talundzic, Aissata Fofana and Mateusz M. Plucinsk Tags: Research Source Type: research

Prevalence and proportion of Plasmodium spp. triple mixed infections compared with double mixed infections: a systematic review and meta-analysis
This study sought to determine the poole... (Source: Malaria Journal)
Source: Malaria Journal - June 24, 2020 Category: Infectious Diseases Authors: Manas Kotepui, Kwuntida Uthaisar Kotepui, Giovanni D. Milanez and Frederick R. Masangkay Tags: Research Source Type: research

Levels of knowledge regarding malaria causes, symptoms, and prevention measures among Malawian women of reproductive age
Malawi is a malaria-endemic country and approximately 6 million cases are reported annually. Improving knowledge of malaria causes and symptoms, and the overall perception towards malaria and its preventive me... (Source: Malaria Journal)
Source: Malaria Journal - June 24, 2020 Category: Infectious Diseases Authors: Alick Sixpence, Owen Nkoka, Gowokani C. Chirwa, Edith B. Milanzi, Charles Mangani, Don P. Mathanga and Peter A. M. Ntenda Tags: Research Source Type: research

Caregiver and community perceptions and experiences participating in an infant malaria prevention trial of PfSPZ Vaccine administered by direct venous inoculation: a qualitative study in Siaya County, western Kenya
Despite available control strategies, malaria morbidity and mortality, especially in infants and young children in sub-Saharan Africa, remain intractable. Malaria vaccination could substantially reduce malaria... (Source: Malaria Journal)
Source: Malaria Journal - June 24, 2020 Category: Infectious Diseases Authors: Florence Achieng, Joseph G. Rosen, Reuben Yego Cherop, Simon Kariuki, Stephen L. Hoffman, Robert Seder, Martina Oneko and Laura C. Steinhardt Tags: Research Source Type: research

In silico analysis for factors affecting anti-malarial penetration into red blood cells
The objective of this study is to investigate the relationships between factors affecting the penetration of currently ava... (Source: Malaria Journal)
Source: Malaria Journal - June 23, 2020 Category: Infectious Diseases Authors: Natapol Pornputtapong, Bovornpat Suriyapakorn, Anchisa Satayamapakorn, Kanidsorn Larpadisorn, Pariyachut Janviriyakul and Phisit Khemawoot Tags: Research Source Type: research

Asymptomatic carriage of Plasmodium falciparum by individuals with variant blood groups and haemoglobin genotypes in southern Ghana
The ABO and the Rhesus blood group systems, as well as various abnormal haemoglobin (Hb) variants (haemoglobinopathies) are known to influence malaria parasite carriage and disease severity in individuals livi... (Source: Malaria Journal)
Source: Malaria Journal - June 23, 2020 Category: Infectious Diseases Authors: Festus K. Acquah, Dickson Donu, Dorcas Bredu, Sophia Eyia-Ampah, Jones A. Amponsah, Joseph Quartey, Evans K. Obboh, Bernice A. Mawuli and Linda E. Amoah Tags: Research Source Type: research

Assays for quantification of male and female gametocytes in human blood by qRT-PCR in the absence of pure sex-specific gametocyte standards
Malaria transmission from humans to Anopheles mosquitoes requires the presence of gametocytes in human peripheral circulation, and the dynamics of transmission are determined largely by the density and sex ratio ... (Source: Malaria Journal)
Source: Malaria Journal - June 23, 2020 Category: Infectious Diseases Authors: Claire Y. T. Wang, Emma Ballard, Stacey Llewellyn, Louise Marquart, Teun Bousema, James S. McCarthy and Katharine A. Collins Tags: Research Source Type: research

Aquatic habitats of the malaria vector Anopheles funestus in rural south-eastern Tanzania
In rural south-eastern Tanzania, Anopheles funestus is a major malaria vector, and has been implicated in nearly 90% of all infective bites. Unfortunately, little is known about the natural ecological requirement... (Source: Malaria Journal)
Source: Malaria Journal - June 23, 2020 Category: Infectious Diseases Authors: Ismail H. Nambunga, Halfan S. Ngowo, Salum A. Mapua, Emmanuel E. Hape, Betwel J. Msugupakulya, Dickson S. Msaky, Nicolaus T. Mhumbira, Karim R. Mchwembo, Gerald Z. Tamayamali, Slyakus V. Mlembe, Rukiyah M. Njalambaha, Dickson W. Lwetoijera, Marceline F. F Tags: Research Source Type: research

Identification and characterization of immature Anopheles and culicines (Diptera: Culicidae) at three sites of varying malaria transmission intensities in Uganda
Over the last two decades, there has been remarkable progress in malaria control in sub-Saharan Africa, due mainly to the massive deployment of long-lasting insecticidal nets and indoor residual spraying. Desp... (Source: Malaria Journal)
Source: Malaria Journal - June 23, 2020 Category: Infectious Diseases Authors: Alex K. Musiime, David L. Smith, Maxwell Kilama, Otto Geoffrey, Patrick Kyagamba, John Rek, Melissa D. Conrad, Joaniter I. Nankabirwa, Emmanuel Arinaitwe, Anne M. Akol, Moses R. Kamya, Grant Dorsey, Sarah G. Staedke, Chris Drakeley and Steve W. Lindsay Tags: Research Source Type: research

Patterns of human exposure to malaria vectors in Zanzibar and implications for malaria elimination efforts
Zanzibar provides a good case study for malaria elimination. The islands have experienced a dramatic reduction in malaria burden since the introduction of effective vector control interventions and case manage... (Source: Malaria Journal)
Source: Malaria Journal - June 22, 2020 Category: Infectious Diseases Authors: April Monroe, Dickson Msaky, Samson Kiware, Brian B. Tarimo, Sarah Moore, Khamis Haji, Hannah Koenker, Steven Harvey, Marceline Finda, Halfan Ngowo, Kimberly Mihayo, George Greer, Abdullah Ali and Fredros Okumu Tags: Research Source Type: research

Coverage of community case management for malaria through CHWs: a quantitative assessment using primary household surveys of high-burden areas in Chhattisgarh state of India
Community Case Management of Malaria (CCMM) has been implemented through community health workers (CHWs) in many countries. Existing studies have shown that CHWs can be viable means of implementing CCMM. Howev... (Source: Malaria Journal)
Source: Malaria Journal - June 22, 2020 Category: Infectious Diseases Authors: Samir Garg, Preeti Gurung, Mukesh Dewangan and Prabodh Nanda Tags: Research Source Type: research

Plasmodium vivax liver stage assay platforms using Indian clinical isolates
Vivax malaria is associated with significant morbidity and economic loss, and constitutes the bulk of malaria cases in large parts of Asia and South America as well as recent case reports in Africa. The widesp... (Source: Malaria Journal)
Source: Malaria Journal - June 22, 2020 Category: Infectious Diseases Authors: Pradeep A. Subramani, Neha Vartak-Sharma, Seetha Sreekumar, Pallavi Mathur, Bhavana Nayer, Sushrut Dakhore, Sowmya K. Basavanna, Devaiah M. Kalappa, Ramya V. Krishnamurthy, Benudhar Mukhi, Priyasha Mishra, Noriko Yoshida, Susanta Kumar Ghosh, Radhakrishan Tags: Research Source Type: research

Loop-mediated isothermal amplification (LAMP) test for diagnosis of uncomplicated malaria in endemic areas: a meta-analysis of diagnostic test accuracy
The global malaria decline has stalled and only a few countries are pushing towards pre-elimination. The aim of the malaria elimination phase is interruption of local transmission of a specified malaria parasi... (Source: Malaria Journal)
Source: Malaria Journal - June 19, 2020 Category: Infectious Diseases Authors: Denesh Selvarajah, Cho Naing, Norah Htet Htet and Joon Wah Mak Tags: Research Source Type: research

Determining a critical threshold for G6PD activity below which red blood cell response to oxidative stress is poor
Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common enzyme disorder in the world. Its main function is to generate NADPH that is required for anti-oxidative pathway in the cells especially i... (Source: Malaria Journal)
Source: Malaria Journal - June 17, 2020 Category: Infectious Diseases Authors: Maria Swastika, Alida R. Harahap, Lydia V. Panggalo, Sri Widia A. Jusman and Ari W. Satyagraha Tags: Research Source Type: research

Monitoring the durability of the long-lasting insecticidal nets MAGNet and Royal Sentry in three ecological zones of Mozambique
Malaria prevention with long-lasting insecticidal nets (LLINs) has seen a tremendous scale-up in sub-Saharan Africa in the last decade. To sustain this success, it is important to understand how long LLINs rem... (Source: Malaria Journal)
Source: Malaria Journal - June 17, 2020 Category: Infectious Diseases Authors: Ana Paula Ab ílio, Emmanuel Obi, Hannah Koenker, Stella Babalola, Abuchahama Saifodine, Rose Zulliger, Isabel Swamidoss, Gabriel Ponce de Leon, Eunice Alfai, Sean Blaufuss, Bolanle Olapeju, Hunter Harig and Albert Kilian Tags: Research Source Type: research

Malaria infection, disease and mortality among children and adults on the coast of Kenya
Malaria transmission has recently fallen in many parts of Africa, but systematic descriptions of infection and disease across all age groups are rare. Here, an epidemiological investigation of parasite prevale... (Source: Malaria Journal)
Source: Malaria Journal - June 17, 2020 Category: Infectious Diseases Authors: Alice Kamau, Grace Mtanje, Christine Mataza, Gabriel Mwambingu, Neema Mturi, Shebe Mohammed, Gerald Ong ’ayo, Gideon Nyutu, Amek Nyaguara, Philip Bejon and Robert W. Snow Tags: Research Source Type: research

Methods and indicators for measuring patterns of human exposure to malaria vectors
Effective targeting and evaluation of interventions that protect against adult malaria vectors requires an understanding of how gaps in personal protection arise. An improved understanding of human and mosquit... (Source: Malaria Journal)
Source: Malaria Journal - June 16, 2020 Category: Infectious Diseases Authors: April Monroe, Sarah Moore, Fredros Okumu, Samson Kiware, Neil F. Lobo, Hannah Koenker, Ellie Sherrard-Smith, John Gimnig and Gerry F. Killeen Tags: Opinion Source Type: research

The thermostability of the RTS,S/AS01 malaria vaccine can be increased by co-lyophilizing RTS,S and AS01
Developing thermostable vaccines is a challenge for pharmaceutical companies due to the inherent instability of biological molecules in aqueous solution. The problem is even more stringent in regions subjected... (Source: Malaria Journal)
Source: Malaria Journal - June 8, 2020 Category: Infectious Diseases Authors: Juliette Fortpied, Sylvie Collignon, Nicolas Moniotte, Fr édéric Renaud, Babak Bayat and Dominique Lemoine Tags: Research Source Type: research

Genetic diversity and genotype multiplicity of Plasmodium falciparum infection in patients with uncomplicated malaria in Chewaka district, Ethiopia
Genetic diversity in Plasmodium falciparum poses a major threat to malaria control and elimination interventions. Characterization of the genetic diversity of P. falciparum strains can be used to assess intensity... (Source: Malaria Journal)
Source: Malaria Journal - June 8, 2020 Category: Infectious Diseases Authors: Abdulhakim Abamecha, Hassan El-Abid, Daniel Yilma, Wondimagegn Addisu, Achim Ibenthal, Abebe Genetu Bayih, Harald Noedl, Delenasaw Yewhalaw, Mohieddine Moumni and Alemseged Abdissa Tags: Research Source Type: research

Anti-malarial activity of traditional Kampo medicine Coptis rhizome extract and its major active compounds
In this study, a variety of Japanese traditional herbal medicine ( ‘Kampo’) were examined for their potential anti-malari... (Source: Malaria Journal)
Source: Malaria Journal - June 8, 2020 Category: Infectious Diseases Authors: Awet Alem Teklemichael, Shusaku Mizukami, Kazufumi Toume, Farhana Mosaddeque, Mohamed Gomaa Kamel, Osamu Kaneko, Katsuko Komatsu, Juntra Karbwang, Nguyen Tien Huy and Kenji Hirayama Tags: Research Source Type: research

Disseminating clinical study results to trial participants in Ethiopia: insights and lessons learned
International regulatory authorities and funders require that research be disseminated promptly and appropriately to all involved stakeholders. However, following completion of clinical trials participants oft... (Source: Malaria Journal)
Source: Malaria Journal - June 8, 2020 Category: Infectious Diseases Authors: Tamiru S. Degaga, Sophie Weston, Tedla T. Tego, Dagimawie T. Abate, Ashenafi Aseffa, Adugna Wayessa, Ric N. Price, Asrat Hailu and Kamala Thriemer Tags: Meeting report Source Type: research

Surveillance of genetic markers associated with Plasmodium falciparum resistance to artemisinin-based combination therapy in Pakistan, 2018 –2019
The spread of artemisinin resistance in the Greater Mekong Subregion of Southeast Asia poses a significant threat for current anti-malarial treatment guidelines globally. The aim of this study was to assess th... (Source: Malaria Journal)
Source: Malaria Journal - June 8, 2020 Category: Infectious Diseases Authors: Abdul Qader Khan, Leyre Pernaute-Lau, Aamer Ali Khattak, Sanna Luijcx, Berit Aydin-Schmidt, Mubashir Hussain, Taj Ali Khan, Farees Uddin Mufti and Ulrika Morris Tags: Research Source Type: research

The epidemiology of Plasmodium falciparum and Plasmodium vivax in East Sepik Province, Papua New Guinea, pre- and post-implementation of national malaria control efforts
In the past decade, national malaria control efforts in Papua New Guinea (PNG) have received renewed support, facilitating nationwide distribution of free long-lasting insecticidal nets (LLINs), as well as imp... (Source: Malaria Journal)
Source: Malaria Journal - June 5, 2020 Category: Infectious Diseases Authors: Johanna H. Kattenberg, Dulcie L. Gumal, Maria Ome-Kaius, Benson Kiniboro, Matthew Philip, Shadrach Jally, Bernadine Kasian, Naomi Sambale, Peter M. Siba, Stephan Karl, Alyssa E. Barry, Ingrid Felger, James W. Kazura, Ivo Mueller and Leanne J. Robinson Tags: Research Source Type: research

Motivations and expectations driving community participation in entomological research projects: Target Malaria as a case study in Bana, Western Burkina Faso
Most field entomology research projects require active participation by local community members. Since 2012, Target Malaria, a not-for-profit research consortium, has been working with residents in the village... (Source: Malaria Journal)
Source: Malaria Journal - June 5, 2020 Category: Infectious Diseases Authors: Nourou Barry, Patrice To é, Lea Pare Toe, Javier Lezaun, Mouhamed Drabo, Roch K. Dabiré and Abdoulaye Diabate Tags: Research Source Type: research

Comparative analysis of asexual and sexual stage Plasmodium falciparum development in different red blood cell types
Red blood cell (RBC) polymorphisms are suggested to influence the course of Plasmodium falciparum malaria. Whereas some variants have been found to be protective, others have been found to enhance parasite develo... (Source: Malaria Journal)
Source: Malaria Journal - June 5, 2020 Category: Infectious Diseases Authors: Linda E. Amoah, Festus K. Acquah, Prince B. Nyarko, Elizabeth Cudjoe, Dickson Donu, Ruth Ayanful-Torgby, Fredericka Sey, Kim C. Williamson and Gordon A. Awandare Tags: Research Source Type: research

Prevalence of mutations in the Plasmodium falciparum chloroquine resistance transporter, PfCRT, and association with ex vivo susceptibility to common anti-malarial drugs against African Plasmodium falciparum isolates
The Plasmodium falciparum chloroquine transporter gene (pfcrt) is known to be involved in chloroquine and amodiaquine resistance, and more particularly the mutations on the loci 72 to 76 localized within the seco... (Source: Malaria Journal)
Source: Malaria Journal - June 5, 2020 Category: Infectious Diseases Authors: Francis Tsombeng Foguim, Herv é Bogreau, Mathieu Gendrot, Joel Mosnier, Isabelle Fonta, Nicolas Benoit, Rémy Amalvict, Marylin Madamet, Sharon Wein and Bruno Pradines Tags: Research Source Type: research

Community factors affecting participation in larval source management for malaria control in Chikwawa District, Southern Malawi
To further reduce malaria, larval source management (LSM) is proposed as a complementary strategy to the existing strategies. LSM has potential to control insecticide resistant, outdoor biting and outdoor rest... (Source: Malaria Journal)
Source: Malaria Journal - June 2, 2020 Category: Infectious Diseases Authors: Steven Gowelo, Robert S. McCann, Constantianus J. M. Koenraadt, Willem Takken, Henk van den Berg and Lucinda Manda-Taylor Tags: Research Source Type: research

Estimating the risk of declining funding for malaria in Ghana: the case for continued investment in the malaria response
Ghana has made impressive progress against malaria, decreasing mortality and morbidity by over 50% between 2005 and 2015. These gains have been facilitated in part, due to increased financial commitment from g... (Source: Malaria Journal)
Source: Malaria Journal - June 1, 2020 Category: Infectious Diseases Authors: Rima Shretta, Sheetal P. Silal, Keziah Malm, Wahjib Mohammed, Joel Narh, Danielle Piccinini, Kathryn Bertram, Jessica Rockwood and Matt Lynch Tags: Research Source Type: research

Malaria outbreak investigation in a rural area south of Zimbabwe: a case –control study
Ninety percent of the global annual malaria mortality cases emanate from the African region. About 80 –90% of malaria transmissions in sub-Saharan Africa occur indoors during the night. In Zimbabwe, 79% of the ... (Source: Malaria Journal)
Source: Malaria Journal - June 1, 2020 Category: Infectious Diseases Authors: Paddington T. Mundagowa and Pugie T. Chimberengwa Tags: Research Source Type: research

Identification of a conserved var gene in different Plasmodium falciparum strains
The multicopy var gene family of Plasmodium falciparum is of crucial importance for pathogenesis and antigenic variation. So far only var2csa, the var gene responsible for placental malaria, was found to be highl... (Source: Malaria Journal)
Source: Malaria Journal - May 29, 2020 Category: Infectious Diseases Authors: Sandra Dimonte, Ellen I. Bruske, Corinna Enderes, Thomas D. Otto, Louise Turner, Peter Kremsner and Matthias Frank Tags: Research Source Type: research

Utility of Plasmodium falciparum DNA from rapid diagnostic test kits for molecular analysis and whole genome amplification
Rapid diagnostic tests (RDTs) have become the most common diagnostic tool for detection of Plasmodium falciparum malaria, in particular in remote areas. RDT blood spots provide a source of parasite DNA for molecu... (Source: Malaria Journal)
Source: Malaria Journal - May 27, 2020 Category: Infectious Diseases Authors: Suttipat Srisutham, Kanokon Suwannasin, Vivek Bhakta Mathema, Kanlaya Sriprawat, Frank M. Smithuis, Francois Nosten, Nicholas J. White, Arjen M. Dondorp and Mallika Imwong Tags: Methodology Source Type: research

Purification and production of Plasmodium falciparum zygotes from in vitro culture using magnetic column and Percoll density gradient
Plasmodium falciparum zygotes develop in the mosquito midgut after an infectious blood meal containing mature male and female gametocytes. Studies of mosquito-produced P. falciparum zygotes to elucidate their bio... (Source: Malaria Journal)
Source: Malaria Journal - May 25, 2020 Category: Infectious Diseases Authors: Yaxian Zhou, Alexis M. Grieser, Julie Do, Leslie S. Itsara, Ashley M. Vaughan and Anil K. Ghosh Tags: Methodology Source Type: research

Evaluation of bio-efficacy and durability of long-lasting insecticidal nets distributed by malaria elimination programme in Eastern India
Long-lasting insecticidal nets (LLINs) are the most favoured vector control tools worldwide. Timely monitoring and evaluation of LLINs is important to sustain the impact of this promising vector control method... (Source: Malaria Journal)
Source: Malaria Journal - May 24, 2020 Category: Infectious Diseases Authors: Sudhansu Sekhar Sahu, Amol Vasantrao Keshaowar, Sonia Thankachy, Dilip Kumar Panigrahi, Premalata Acharya, Vijayakumar Balakrishnan and Ashwani Kumar Tags: Research Source Type: research

Monitoring the durability of the long-lasting insecticidal nets Olyset ® and PermaNet® 2.0 in similar use environments in Zanzibar
Malaria transmission in Zanzibar has dramatically reduced in recent years but vector control interventions such as long-lasting insecticidal nets (LLIN) must continue to reach malaria elimination. To achieve t... (Source: Malaria Journal)
Source: Malaria Journal - May 24, 2020 Category: Infectious Diseases Authors: Khamis Ameir Haji, Bakari Omar Khatib, Emmanuel Obi, Kanuth Dimoso, Hannah Koenker, Stella Babalola, George Greer, Naomi Serbantez, Faiza Abbas, Abdullah Ali, Sean Blaufuss, Bolanle Olapeju and Albert Kilian Tags: Research Source Type: research

Comparing the durability of the long-lasting insecticidal nets DawaPlus ® 2.0 and DuraNet© in northwest Democratic Republic of Congo
Anecdotal reports from DRC suggest that long-lasting insecticidal nets (LLIN) distributed through mass campaigns in DRC may not last the expected average three years. To provide the National Malaria Control Pr... (Source: Malaria Journal)
Source: Malaria Journal - May 24, 2020 Category: Infectious Diseases Authors: Paul Mansiangi, Solange Umesumbu, Ir ène Etewa, Jacques Zandibeni, Nissi Bafwa, Sean Blaufuss, Bolanle Olapeju, Ferdinand Ntoya, Aboubacar Sadou, Seth Irish, Eric Mukomena, Lydie Kalindula, Francis Watsenga, Martin Akogbeto, Stella Babalola, Hannah Koenk Tags: Research Source Type: research

Prevalence of pfdhfr and pfdhps mutations in Plasmodium falciparum associated with drug resistance among pregnant women receiving IPTp-SP at Msambweni County Referral Hospital, Kwale County, Kenya
Prevention and treatment of malaria during pregnancy is crucial in dealing with maternal mortality and adverse fetal outcomes. The World Health Organization recommendation to treat all pregnant women with sulf... (Source: Malaria Journal)
Source: Malaria Journal - May 24, 2020 Category: Infectious Diseases Authors: Stella Wanjiku Gikunju, Eric L. Agola, Raphael Omusebe Ondondo, Johnson Kinyua, Francis Kimani, Angelle Desiree LaBeaud, Indu Malhotra, Charles King, Kelvin Thiong ’o and Francis Mutuku Tags: Research Source Type: research

Molecular assessment of kelch13 non-synonymous mutations in Plasmodium falciparum isolates from Central African Republic (2017 –2019)
Over the last decade, artemisinin-based combination therapy (ACT) has contributed substantially to the decrease in malaria-related morbidity and mortality. The emergence of Plasmodium falciparum parasites resista... (Source: Malaria Journal)
Source: Malaria Journal - May 24, 2020 Category: Infectious Diseases Authors: Romaric Nzoumbou-Boko, Chris-Boris Gildas Pant é-Wockama, Carine Ngoagoni, Nathalie Petiot, Eric Legrand, Ulrich Vickos, Jean-Chrysostome Gody, Alexandre Manirakiza, Christophe Ndoua, Jean-Pierre Lombart and Didier Ménard Tags: Research Source Type: research

Scaling up malaria elimination management and leadership: a pilot in three provinces in Zimbabwe, 2016 –2018
Focus for improved malaria programme performance is often placed on the technical challenges, while operational issues are neglected. Many of the operational challenges that inhibit malaria programme effective... (Source: Malaria Journal)
Source: Malaria Journal - May 20, 2020 Category: Infectious Diseases Authors: Amanda Marr Chung, Peter Case, Jonathan Gosling, Roland Gosling, Munashe Madinga, Rudo Chikodzore, Macdonald Hove, Greyling Viljoen, Precious Chitapi, Matsiliso Gumbi, Peliwe Mnguni, Joseph Murungu, Busisani Dube, Patience Dhliwayo and Joseph Mberikunashe Tags: Research Source Type: research