A simple, field-applicable method to increase the infectivity of wild isolates of Plasmodium falciparum to mosquito vectors
The direct membrane feeding assay (DMFA), whereby gametocyte-infected blood is collected from human donors and from which mosquitoes feed through a membrane, is proving essential for assessing parameters influ... (Source: Malaria Journal)
Source: Malaria Journal - May 6, 2024 Category: Infectious Diseases Authors: Seydou Bienvenu Ouattara, Domonbabele F. D. S. Hien, Ek ôbié T. Nao, Prisca S. L. Paré, Edwige Guissou, Anna Cohuet, Isabelle Morlais, Rakiswendé S. Yerbanga, Kounbobr R. Dabiré, Jean Bosco Ouédraogo, Karine Mouline and Thierry Lefèvre Tags: Research Source Type: research
Leveraging malaria vaccines and mRNA technology to tackle the global inequity in pharmaceutical research and production towards disease elimination
This article examines the inequity in the global pharmaceutical research, development, manufactu... (Source: Malaria Journal)
Source: Malaria Journal - May 6, 2024 Category: Infectious Diseases Authors: Floriano Amimo Tags: Perspective Source Type: research
A new long-read mitochondrial-genome protocol (PacBio HiFi) for haemosporidian parasites: a tool for population and biodiversity studies
Studies on haemosporidian diversity, including origin of human malaria parasites, malaria's zoonotic dynamic, and regional biodiversity patterns, have used target gene approaches. However, current methods have... (Source: Malaria Journal)
Source: Malaria Journal - May 4, 2024 Category: Infectious Diseases Authors: M. Andre ína Pacheco, Axl S. Cepeda, Erica A. Miller, Scott Beckerman, Mitchell Oswald, Evan London, Nohra E. Mateus-Pinilla and Ananias A. Escalante Tags: Research Source Type: research
Statistical design and analysis of controlled human malaria infection trials
Malaria is a potentially life-threatening disease caused by Plasmodium protozoa transmitted by infected Anopheles mosquitoes. Controlled human malaria infection (CHMI) trials are used to assess the efficacy of in... (Source: Malaria Journal)
Source: Malaria Journal - May 3, 2024 Category: Infectious Diseases Authors: Xiaowen Tian, Holly E. Janes and James G. Kublin Tags: Research Source Type: research
Predictors of accessing seasonal malaria chemoprevention medicines through non-door-to-door distribution in Nigeria
In Nigeria, seasonal malaria chemoprevention (SMC) is typically administered door-to-door to children under five by community medicine distributors during high transmission seasons. While door-to-door distribu... (Source: Malaria Journal)
Source: Malaria Journal - May 3, 2024 Category: Infectious Diseases Authors: Sikai Huang, Kevin Baker, Taiwo Ibinaiye, Olusola Oresanya, Chuks Nnaji and Sol Richardson Tags: Research Source Type: research
Repurposing of anti-malarial drugs for the treatment of tuberculosis: realistic strategy or fanciful dead end?
Drug repurposing offers a strategic alternative to the development of novel compounds, leveraging the known safety and pharmacokinetic profiles of medications, such as linezolid and levofloxacin for tuberculos... (Source: Malaria Journal)
Source: Malaria Journal - May 3, 2024 Category: Infectious Diseases Authors: Thomas Hanscheid, Claire Ruiz del Portal Luyten, Sabine M. Hermans and Martin P. Grobusch Tags: Review Source Type: research
Plasmodium falciparum alters the trophoblastic barrier and stroma villi organization of human placental villi explants
The sequestration of Plasmodium falciparum infected erythrocytes in the placenta, and the resulting inflammatory response affects maternal and child health. Despite existing information, little is known about the... (Source: Malaria Journal)
Source: Malaria Journal - May 1, 2024 Category: Infectious Diseases Authors: Carolina L ópez-Guzmán, Ana María García, Juan Diego Ramirez, Trinidad Torres Aliaga, Alejandro Fernández-Moya, Ulrike Kemmerling and Ana María Vásquez Tags: Research Source Type: research
Exploring the role of spending on malaria incidence in Uganda using the auto-regressive distributed lag approach
Malaria has remained a persistent global health problem. Despite multiple government and donor initiatives to eradicate malaria and its detrimental effects on Uganda's health outcomes, the incidence of malaria... (Source: Malaria Journal)
Source: Malaria Journal - April 30, 2024 Category: Infectious Diseases Authors: Jemimah Katushabe, John Bosco Nnyanzi and Gertrude Sebunya Muwanga Tags: Research Source Type: research
Field evaluation of the residual efficacy of new generation insecticides for potential use in indoor residual spray programmes in South Africa
The decreasing residual efficacy of insecticides is an important factor when making decisions on insecticide choice for national malaria control programmes. The major challenge to using chemicals for vector co... (Source: Malaria Journal)
Source: Malaria Journal - April 30, 2024 Category: Infectious Diseases Authors: Rajendra Maharaj, Ishen Seocharan, Vishan Lakan, Zuziwe Nyawo, Moses Mkhabela and Yusentha Balakrishna Tags: Research Source Type: research
Access to quality-assured artemisinin-based combination therapy and associated factors among clients of selected private drug outlets in Uganda
Malaria treatment in sub-Saharan Africa is faced with challenges including unreliable supply of efficacious agents, substandard medicines coupled with high price of artemisinin-based combinations. This affects... (Source: Malaria Journal)
Source: Malaria Journal - April 30, 2024 Category: Infectious Diseases Authors: Moses Ocan, Loyce Nakalembe, Caroline Otike, Tayebwa Mordecai, Joan Birungi and Sam Nsobya Tags: Research Source Type: research
Therapeutic efficacy of generic artemether –lumefantrine in the treatment of uncomplicated malaria in Ghana: assessing anti-malarial efficacy amidst pharmacogenetic variations
Despite efforts made to reduce morbidity and mortality associated with malaria, especially in sub-Saharan Africa, malaria continues to be a public health concern that requires innovative efforts to reach the W... (Source: Malaria Journal)
Source: Malaria Journal - April 29, 2024 Category: Infectious Diseases Authors: Nicholas Ekow Thomford, Tracy Kellermann, Robert Peter Biney, Charn é Dixon, Samuel Badu Nyarko, Richmond Owusu Ateko, Martins Ekor and George B. Kyei Tags: Research Source Type: research
Blood count changes in malaria patients according to blood groups (ABO/Rh) and sickle cell trait
Introduction: Malaria continues to be the leading cause of hospitalization and death in Angola, a country in sub- Saharan Africa. In 2023, in the first quarter, 2,744,682 cases were registered, and of these 2,... (Source: Malaria Journal)
Source: Malaria Journal - April 29, 2024 Category: Infectious Diseases Authors: Euclides N. M. Sacomboio, Santo D. Zua, Adelino T. Tchivango, Ant ónio D. Pululu, Adilson C. D. Caumba, Adelina B. M. Paciência, Danilson V. Sati, Sabina G. Agostinho, Yolanda S. Agostinho, Fernando G. Mazanga, Neusa B. Ntambo, Cruz S. Sebastião, Joana Tags: Research Source Type: research
Factors influencing fever care-seeking for children under five years of age in The Gambia: a secondary analysis of 2019 –20 DHS data
Malaria contributes to excess child mortality in The Gambia. Children under five are at risk of severe malaria and death if not treated promptly and appropriately. It is crucial that a child with fever receive... (Source: Malaria Journal)
Source: Malaria Journal - April 27, 2024 Category: Infectious Diseases Authors: Laura Arntson, Katherine R. McLaughlin and Ellen Smit Tags: Research Source Type: research
Fidelity of implementation of national guidelines on malaria diagnosis for children under-five years in Rivers State, Nigeria
Malaria is still a disease of global public health importance and children under-five years of age are the most vulnerable to the disease. Nigeria adopted the “test and treat” strategy in the national malaria ... (Source: Malaria Journal)
Source: Malaria Journal - April 27, 2024 Category: Infectious Diseases Authors: Mina Whyte, Latifat Ibisomi, Tobias Chirwa, Jonathan Levin and Wiedaad Slemming Tags: Research Source Type: research
Identifying and characterizing high-risk populations in pilot malaria elimination districts in Madagascar: a mixed-methods study
In Madagascar, the districts of Antsirabe II, Faratsiho and Antsiranana I have relatively low malaria incidence rates and have been selected by the National Malaria Control Programme for pilot elimination stra... (Source: Malaria Journal)
Source: Malaria Journal - April 26, 2024 Category: Infectious Diseases Authors: Elisabeth Gebreegziabher, Andry Raoliarison, Andrinirina Ramananjato, Andriamamonjy Fanomezana, Martin Rafaliarisoa, Sandy Ralisata, Jocelyn Razafindrakoto, Jennifer L. Smith, Jehan Ahmed and Cara Smith Gueye Tags: Research Source Type: research
