Analysis of the lymphocyte cell population during malaria caused by Plasmodium vivax and its correlation with parasitaemia and thrombocytopaenia
The mechanisms of activation and regulation of T lymphocytes and their cytokines in malaria caused by Plasmodium vivax are complex and poorly understood. Previous data suggest that T cells balance protective imm... (Source: Malaria Journal)
Source: Malaria Journal - August 20, 2018 Category: Infectious Diseases Authors: Samantha Soares Ourives, Quessi Irias Borges, Diego Sampaio Arantes dos Santos, Eponina Cl áudia Magalhães Melo, Rodrigo Medeiros de Souza and Amílcar Sabino Damazo Tags: Research Source Type: research

Does livestock protect from malaria or facilitate malaria prevalence? A cross-sectional study in endemic rural areas of Indonesia
Ever since it was discovered that zoophilic vectors can transmit malaria, zooprophylaxis has been used to prevent the disease. However, zoopotentiation has also been observed. Thus, the presence of livestock h... (Source: Malaria Journal)
Source: Malaria Journal - August 20, 2018 Category: Infectious Diseases Authors: Hamzah Hasyim, Meghnath Dhimal, Jan Bauer, Doreen Montag, David A. Groneberg, Ulrich Kuch and Ruth M üller Tags: Research Source Type: research

Diversity pattern of Duffy binding protein sequence among Duffy-negatives and Duffy-positives in Sudan
Vivax malaria is a leading public health concern worldwide. Due to the high prevalence of Duffy-negative blood group population, Plasmodium vivax in Africa historically is less attributable and remains a neglecte... (Source: Malaria Journal)
Source: Malaria Journal - August 17, 2018 Category: Infectious Diseases Authors: Mohammad Rafiul Hoque, Mohammed Mohieldien Abbas Elfaki, Md Atique Ahmed, Seong-Kyun Lee, Fauzi Muh, Musab M. Ali Albsheer, Muzamil Mahdi Abdel Hamid and Eun-Taek Han Tags: Research Source Type: research

Agent-based models of malaria transmission: a systematic review
Much of the extensive research regarding transmission of malaria is underpinned by mathematical modelling. Compartmental models, which focus on interactions and transitions between population strata, have been... (Source: Malaria Journal)
Source: Malaria Journal - August 17, 2018 Category: Infectious Diseases Authors: Neal R. Smith, James M. Trauer, Manoj Gambhir, Jack S. Richards, Richard J. Maude, Jonathan M. Keith and Jennifer A. Flegg Tags: Research Source Type: research

Housing gaps, mosquitoes and public viewpoints: a mixed methods assessment of relationships between house characteristics, malaria vector biting risk and community perspectives in rural Tanzania
This study assessed the influence of physical characteristics of houses and surroun... (Source: Malaria Journal)
Source: Malaria Journal - August 17, 2018 Category: Infectious Diseases Authors: Emmanuel W. Kaindoa, Marceline Finda, Jepchirchir Kiplagat, Gustav Mkandawile, Anna Nyoni, Maureen Coetzee and Fredros O. Okumu Tags: Research Source Type: research

Isolation, characterization, and biological evaluation of a potent anti-malarial drimane sesquiterpene from Warburgia salutaris stem bark
Malaria continues to be a global burden as the efficacy of most commercial anti-malarial drugs has been compromised by the evolution of parasite resistance. With the urgent need created for the development of ... (Source: Malaria Journal)
Source: Malaria Journal - August 15, 2018 Category: Infectious Diseases Authors: Zoxolo N. Nyaba, Pretty Murambiwa, Andy R. Opoku, Samson Mukaratirwa, Francis O. Shode and Mthokozisi B. C. Simelane Tags: Research Source Type: research

Malaria control and chemoprophylaxis policy in the Republic of Korea Armed Forces for the previous 20 years (1997 –2016)
Vivax malaria reemerged along the Demilitarized Zone (DMZ), Republic of Korea (ROK), in 1993. While it was hypothesized that vivax malaria would spread throughout the peninsula, nearly all cases were due to ex... (Source: Malaria Journal)
Source: Malaria Journal - August 15, 2018 Category: Infectious Diseases Authors: Jae Hyoung Im, Kyungmin Huh, Chang-Gyo Yoon, Hyeongtaek Woo, Jin-Soo Lee, Moon-Hyun Chung, Terry A. Klein and Jaehun Jung Tags: Case study Source Type: research

Comparative 1D Blue-Native electrophoresis analysis of Plasmodium falciparum and human proteins associated with cytoadherence
To understand more about changes to the molecular components that occur when host endothelium interacts with Plasmodium falciparum-infected erythrocytes, a combined technique of protein separation (1D Blue-Native... (Source: Malaria Journal)
Source: Malaria Journal - August 13, 2018 Category: Infectious Diseases Authors: Yang Wu, Simon C. Wagstaff, Saeed A. Al-Harthi and Alister G. Craig Tags: Research Source Type: research

Epidemiological characterization of malaria in rural southern Tanzania following China-Tanzania pilot joint malaria control baseline survey
Malaria is an important public health problem in Tanzania. The latest national malaria data suggests rebound of the disease in the country. Anopheles arabiensis, a mosquito species renowned for its resilience aga... (Source: Malaria Journal)
Source: Malaria Journal - August 13, 2018 Category: Infectious Diseases Authors: Rashid A. Khatib, Prosper P. Chaki, Duo-Quan Wang, Yeromin P. Mlacha, Michael G. Mihayo, Tegemeo Gavana, Ning Xiao, Xiao-Nong Zhou and Salim Abdullah Tags: Research Source Type: research

Metabolism of primaquine in normal human volunteers: investigation of phase I and phase II metabolites from plasma and urine using ultra-high performance liquid chromatography-quadrupole time-of-flight mass spectrometry
Primaquine (PQ), an 8-aminoquinoline, is the only drug approved by the United States Food and Drug Administration for radical cure and prevention of relapse in Plasmodium vivax infections. Knowledge of the metabo... (Source: Malaria Journal)
Source: Malaria Journal - August 13, 2018 Category: Infectious Diseases Authors: Bharathi Avula, Babu L. Tekwani, Narayan D. Chaurasiya, Pius Fasinu, N. P. Dhammika Nanayakkara, H. M. T. Bhandara Herath, Yan-Hong Wang, Ji-Yeong Bae, Shabana I. Khan, Mahmoud A. Elsohly, James D. McChesney, Peter A. Zimmerman, Ikhlas A. Khan and Larry A Tags: Research Source Type: research

The portfolio effect cushions mosquito populations and malaria transmission against vector control interventions
Portfolio effects were first described as a basis for mitigating against financial risk by diversifying investments. Distributing investment across several different assets can stabilize returns and reduce ris... (Source: Malaria Journal)
Source: Malaria Journal - August 10, 2018 Category: Infectious Diseases Authors: Gerry F. Killeen and Thomas E. Reed Tags: Opinion Source Type: research

Sense of community and willingness to support malaria intervention programme in urban poor Accra, Ghana
This study assesses the impact of individuals’ sense of community (perce... (Source: Malaria Journal)
Source: Malaria Journal - August 10, 2018 Category: Infectious Diseases Authors: D. Yaw Atiglo, Reuben Tete Larbi, Mawuli Komla Kushitor, Adriana A. E. Biney, Paapa Yaw Asante, Naa Dodua Dodoo and F. Nii-Amoo Dodoo Tags: Research Source Type: research

Travel to farms in the lowlands and inadequate malaria information significantly predict malaria in villages around Lake Tana, northwest Ethiopia: a matched case –control study
In Ethiopia, malaria has declined in the last decade; only a small number of cases have been reported, primarily from hotspots. The contribution of house proximity to water bodies and the role of migration in ... (Source: Malaria Journal)
Source: Malaria Journal - August 10, 2018 Category: Infectious Diseases Authors: Asmamaw Malede, Kassahun Alemu, Mulugeta Aemero, Sirak Robele and Helmut Kloos Tags: Research Source Type: research

Chimeric Plasmodium falciparum parasites expressing Plasmodium vivax circumsporozoite protein fail to produce salivary gland sporozoites
Rodent malaria parasites where the gene encoding circumsporozoite protein (CSP) has been replaced with csp genes from the human malaria parasites, Plasmodium falciparum or Plasmodium vivax, are used as pre-clinic... (Source: Malaria Journal)
Source: Malaria Journal - August 9, 2018 Category: Infectious Diseases Authors: Catherin Marin-Mogollon, Fiona J. A. van Pul, Shinya Miyazaki, Takashi Imai, Jai Ramesar, Ahmed M. Salman, Beatrice M. F. Winkel, Ahmad Syibli Othman, Hans Kroeze, Severine Chevalley-Maurel, Arturo Reyes-Sandoval, Meta Roestenberg, Blandine Franke-Fayard, Tags: Research Source Type: research

Correction to: Individual and household characteristics of persons with Plasmodium falciparum malaria in sites with varying endemicities in Kinshasa Province, Democratic Republic of the Congo
Unfortunately after publication of the original article [1], it came to the author ’s attention that there is an error in the caption of Fig. 2. (Source: Malaria Journal)
Source: Malaria Journal - August 8, 2018 Category: Infectious Diseases Authors: Melchior Kashamuka Mwandagalirwa, Lauren Levitz, Kyaw L. Thwai, Jonathan B. Parr, Varun Goel, Mark Janko, Antoinette Tshefu, Michael Emch, Steven R. Meshnick and Margaret Carrel Tags: Correction Source Type: research

Imported and autochthonous malaria in West Saudi Arabia: results from a reference hospital
The Kingdom of Saudi Arabia is seeking malaria eradication. Malaria transmission has been very low over the last few years. Discovered cases of Plasmodium falciparum infection are assigned a treatment protocol of... (Source: Malaria Journal)
Source: Malaria Journal - August 7, 2018 Category: Infectious Diseases Authors: Rasha Hassan Soliman, Patricia Garcia-Aranda, Sherine Mohamed Elzagawy, Boshra El-Sayed Hussein, Wael Wahid Mayah, Alexandra Martin Ramirez, Thuy-Huong Ta-Tang and Jos é Miguel Rubio Tags: Research Source Type: research

Efficacy of artesunate –amodiaquine in the treatment of falciparum uncomplicated malaria in Madagascar
Since 2006, the artemisinin-based combination therapy (ACT) are recommended to treat uncomplicated malaria including non Plasmodium falciparum malaria in Madagascar. Artesunate –amodiaquine (ASAQ) and artemether–l... (Source: Malaria Journal)
Source: Malaria Journal - August 6, 2018 Category: Infectious Diseases Authors: Om éga Raobela, Valérie Andriantsoanirina, David Gael Rajaonera, Tovonahary Angelo Rakotomanga, Stéphane Rabearimanana, Fanomezantsoa Ralinoro, Didier Ménard and Arsène Ratsimbasoa Tags: Research Source Type: research

Reduced-representation sequencing identifies small effective population sizes of Anopheles gambiae in the north-western Lake Victoria basin, Uganda
Malaria is the leading cause of global paediatric mortality in children below 5 years of age. The number of fatalities has reduced significantly due to an expansion of control interventions but the development... (Source: Malaria Journal)
Source: Malaria Journal - August 6, 2018 Category: Infectious Diseases Authors: Rachel M. Wiltshire, Christina M. Bergey, Jonathan K. Kayondo, Josephine Birungi, Louis G. Mukwaya, Scott J. Emrich, Nora J. Besansky and Frank H. Collins Tags: Research Source Type: research

A bioreactor system for the manufacture of a genetically modified Plasmodium falciparum blood stage malaria cell bank for use in a clinical trial
Although the use of induced blood stage malaria infection has proven to be a valuable tool for testing the efficacy of vaccines and drugs against Plasmodium falciparum, a limiting factor has been the availability... (Source: Malaria Journal)
Source: Malaria Journal - August 6, 2018 Category: Infectious Diseases Authors: Rebecca Pawliw, Rebecca Farrow, Silvana Sekuloski, Helen Jennings, Julie Healer, Thuan Phuong, Pri Sathe, Cielo Pasay, Krystal Evans, Alan F. Cowman, Louis Schofield, Nanhua Chen, James McCarthy and Katharine Trenholme Tags: Methodology Source Type: research

An inexpensive open source 3D-printed membrane feeder for human malaria transmission studies
The study of malaria transmission requires the experimental infection of mosquitoes with Plasmodium gametocytes. In the laboratory, this is achieved using artificial membrane feeding apparatus that simulate body ... (Source: Malaria Journal)
Source: Malaria Journal - August 3, 2018 Category: Infectious Diseases Authors: Kathrin Witmer, Ellie Sherrard-Smith, Ursula Straschil, Mark Tunnicliff, Jake Baum and Michael Delves Tags: Methodology Source Type: research

Implications of population-level immunity for the emergence of artemisinin-resistant malaria: a mathematical model
Artemisinin-resistant Plasmodium falciparum has emerged in the Greater Mekong Subregion, an area of relatively low transmission, but has yet to be reported in Africa. A population-based mathematical model was use... (Source: Malaria Journal)
Source: Malaria Journal - August 2, 2018 Category: Infectious Diseases Authors: Nick Scott, Ricardo Ataide, David P. Wilson, Margaret Hellard, Ric N. Price, Julie A. Simpson and Freya J. I. Fowkes Tags: Research Source Type: research

Low and heterogeneous prevalence of glucose-6-phosphate dehydrogenase deficiency in different settings in Ethiopia using phenotyping and genotyping approaches
8-Aminoquinolines such as primaquine clear mature Plasmodium falciparum gametocytes that are responsible for transmission from human to mosquitoes and bring radical cure in Plasmodium vivax by clearing dormant li... (Source: Malaria Journal)
Source: Malaria Journal - August 2, 2018 Category: Infectious Diseases Authors: Getasew Shitaye, Endalamaw Gadisa, Lynn Grignard, Girma Shumie, Wakweya Chali, Temesgen Menberu, Mulualem Belachew, Getaneh Tegegn, Sagni Challi, Jonathan Curry, Laleta Mahey, Tsegaye Hailu, Hassen Mamo, Menakath Menon, Taye Balcha, Abraham Aseffa & helli Tags: Research Source Type: research

Factors associated with caregivers ’ consistency of use of bed nets in Nigeria: a multilevel multinomial analysis of survey data
Malaria remains endemic in Nigeria despite programmes and policies put in place toward malaria elimination. Long-lasting insecticidal nets have been documented to offer protection from malaria by preventing mo... (Source: Malaria Journal)
Source: Malaria Journal - August 2, 2018 Category: Infectious Diseases Authors: Stella Babalola, Sulaimon T. Adedokun, Anna McCartney-Melstad, Mathew Okoh, Sola Asa, Ian Tweedie and Andrew Tompsett Tags: Research Source Type: research

Identifying risk factors for the development of sepsis during adult severe malaria
The objective of this analysis was to develop a prognostic model to identify p... (Source: Malaria Journal)
Source: Malaria Journal - July 31, 2018 Category: Infectious Diseases Authors: Tsi Njim, Arjen Dondorp, Mavuto Mukaka and Eric O. Ohuma Tags: Research Source Type: research

Correction to: Malaria and other febrile diseases among travellers: the experience of a reference centre located outside the Brazilian Amazon Region
Following publication of the original article [1], one of the authors flagged that unfortunately their last name, Doltario, was incorrectly spelled as ‘Dotrário’. This has since been corrected in the original ... (Source: Malaria Journal)
Source: Malaria Journal - July 30, 2018 Category: Infectious Diseases Authors: Andr éa Beltrami Doltario, Lucas José Bazzo Menon, Valdes Roberto Bollela, Roberto Martinez, Daniel Cardoso de Almeida e Araújo, Benedito Antônio Lopes da Fonseca and Rodrigo de C. Santana Tags: Correction Source Type: research

A standard photomap of the ovarian nurse cell chromosomes for the dominant malaria vector in Europe and Middle East Anopheles sacharovi
Anopheles sacharovi is a dominant malaria vector species in South Europe and the Middle East which has a highly plastic behaviour at both adult and larval stages. Such plasticity has prevented this species from e... (Source: Malaria Journal)
Source: Malaria Journal - July 30, 2018 Category: Infectious Diseases Authors: Gleb N. Artemov, Alena I. Velichevskaya, Semen M. Bondarenko, Gayane H. Karagyan, Sargis A. Aghayan, Marine S. Arakelyan, Vladimir N. Stegniy, Igor V. Sharakhov and Maria V. Sharakhova Tags: Research Source Type: research

Immunological characterization of Plasmodium vivax Pv32, a novel predicted GPI-anchored merozoite surface protein
The development of an effective malarial vaccine is an urgent need. Most glycosylphosphatidylinositol (GPI)-anchored proteins of Plasmodium parasites are exposed to neutralizing antibodies, and several are advanc... (Source: Malaria Journal)
Source: Malaria Journal - July 27, 2018 Category: Infectious Diseases Authors: Yang Cheng, Bo Wang, Feng Lu, Jin-Hee Han, Md Atique Ahmed and Eun-Taek Han Tags: Research Source Type: research

Plasmodium 18S rRNA of intravenously administered sporozoites does not persist in peripheral blood
Plasmodium 18S rRNA is a biomarker used to monitor blood-stage infections in malaria clinical trials. Plasmodium sporozoites also express this biomarker, and there is conflicting evidence about how long sporozoit... (Source: Malaria Journal)
Source: Malaria Journal - July 27, 2018 Category: Infectious Diseases Authors: Sean C. Murphy, Andrew S. Ishizuka, Zachary P. Billman, Tayla M. Olsen, Annette M. Seilie, Ming Chang, Nahum Smith, Vorada Chuenchob, Sumana Chakravarty, B. Kim Lee Sim, Stefan H. I. Kappe, Stephen L. Hoffman and Robert A. Seder Tags: Research Source Type: research

In vitro invasion inhibition assay using antibodies against Plasmodium knowlesi Duffy binding protein alpha and apical membrane antigen protein 1 in human erythrocyte-adapted P. knowlesi A1-H.1 strain
The rapid process of malaria erythrocyte invasion involves ligand –receptor interactions. Inducing antibodies against specific ligands or receptors that abrogate the invasion process is a key challenge for blo... (Source: Malaria Journal)
Source: Malaria Journal - July 27, 2018 Category: Infectious Diseases Authors: Fauzi Muh, Seong-Kyun Lee, Mohammad Rafiul Hoque, Jin-Hee Han, Ji-Hoon Park, Egy Rahman Firdaus, Robert W. Moon, Yee Ling Lau and Eun-Taek Han Tags: Research Source Type: research

Diversity and natural selection on the thrombospondin-related adhesive protein (TRAP) gene of Plasmodium knowlesi in Malaysia
Plasmodium knowlesi a parasite of the macaques is currently the most common cause of human malaria in Malaysia. The thrombospondin-related adhesive protein (TRAP) gene is pre-erythrocytic stage antigen. It is a w... (Source: Malaria Journal)
Source: Malaria Journal - July 27, 2018 Category: Infectious Diseases Authors: Md Atique Ahmed, Yee Ling Lau and Fu-Shi Quan Tags: Research Source Type: research

Genetic diversity and population structure of malaria vector mosquitoes Anopheles subpictus, Anopheles peditaeniatus, and Anopheles vagus in five districts of Sri Lanka
Although Sri Lanka is considered as a malaria-free nation, the threat of re-emergence of outbreaks still remains due to the high prevalence and abundance of malaria vectors. Analysis of population genetic stru... (Source: Malaria Journal)
Source: Malaria Journal - July 20, 2018 Category: Infectious Diseases Authors: Thilini C. Weeraratne, Sinnathambi N. Surendran, Catherine Walton and S. H. P. Parakrama Karunaratne Tags: Research Source Type: research

Self-assembling functional programmable protein array for studying protein –protein interactions in malaria parasites
Plasmodium vivax is the most widespread malarial species, causing significant morbidity worldwide. Knowledge is limited regarding the molecular mechanism of invasion due to the lack of a continuous in vitro cultu... (Source: Malaria Journal)
Source: Malaria Journal - July 17, 2018 Category: Infectious Diseases Authors: Gabriela Ar évalo-Pinzón, María González-González, Carlos Fernando Suárez, Hernando Curtidor, Javier Carabias-Sánchez, Antonio Muro, Joshua LaBaer, Manuel Alfonso Patarroyo and Manuel Fuentes Tags: Research Source Type: research

Pharmacokinetics of mefloquine administered with artesunate in patients with uncomplicated falciparum malaria from the Brazilian Amazon basin
A fixed-dose combination of mefloquine with artesunate was evaluated in cases of falciparum malaria in the Brazilian Amazon basin with acceptable efficacy, safety and tolerability. However, there are no data o... (Source: Malaria Journal)
Source: Malaria Journal - July 16, 2018 Category: Infectious Diseases Authors: Michelle V. D. Ferreira, Jos é L. F. Vieira, Eduardo D. Almeida, Juan G. B. Rivera, Margarete S. M. Gomes and André M. de Siqueira Tags: Research Source Type: research

Genetic polymorphisms in the circumsporozoite protein of Plasmodium malariae show a geographical bias
Plasmodium malariae is characterized by its long asymptomatic persistence in the human host. The epidemiology of P. malariae is incompletely understood and is hampered by the limited knowledge of genetic polymorp... (Source: Malaria Journal)
Source: Malaria Journal - July 16, 2018 Category: Infectious Diseases Authors: Naowarat Saralamba, Mayfong Mayxay, Paul N. Newton, Frank Smithuis, Francois Nosten, Laypaw Archasuksan, Sasithon Pukrittayakamee, Nicholas J. White, Nicholas P. J. Day, Arjen M. Dondorp and Mallika Imwong Tags: Research Source Type: research

Chloroquine resistance is associated to multi-copy pvcrt-o gene in Plasmodium vivax malaria in the Brazilian Amazon
The resistance of Plasmodium vivax to chloroquine has become an obstacle to control strategies based on the use of anti-malarials. The current study investigated the association between P. vivax CQ-resistance in ... (Source: Malaria Journal)
Source: Malaria Journal - July 16, 2018 Category: Infectious Diseases Authors: Siuhelem Rocha Silva, Anne Cristine Gomes Almeida, George Allan Villarouco da Silva, Rajendranath Ramasawmy, Stefanie Costa Pinto Lopes, Andr é Machado Siqueira, Gabriel Luíz Costa, Taís Nóbrega Sousa, José Luiz Fernandes Vieira, Marcus Vinícius Gui Tags: Research Source Type: research

Environmental health risks and benefits of the use of mosquito coils as malaria prevention and control strategy
Malaria is an infectious disease that causes many deaths in sub-Saharan Africa. In resource-poor malaria endemic communities, mosquito coils are commonly applied in households to repel the vector mosquito that... (Source: Malaria Journal)
Source: Malaria Journal - July 16, 2018 Category: Infectious Diseases Authors: Jonathan N. Hogarh, Thomas P. Agyekum, Crentsil Kofi Bempah, Emmanuel D. J. Owusu-Ansah, Silas W. Avicor, Gordon A. Awandare, Julius N. Fobil and Kwasi Obiri-Danso Tags: Research Source Type: research

A cross-sectional analysis of ITN and IRS coverage in Namibia in 2013
Achieving vector control targets is a key step towards malaria elimination. Because of variations in reporting of progress towards vector control targets in 2013, the coverage of these vector control intervent... (Source: Malaria Journal)
Source: Malaria Journal - July 16, 2018 Category: Infectious Diseases Authors: Sophie H. Allcock, Elizabeth H. Young and Manjinder S. Sandhu Tags: Research Source Type: research

Diagnostic accuracy of loop-mediated isothermal amplification (LAMP) for screening malaria in peripheral and placental blood samples from pregnant women in Colombia
Pregnant women frequently show low-density Plasmodium infections that require more sensitive methods for accurate diagnosis and early treatment of malaria. This is particularly relevant in low-malaria transmissio... (Source: Malaria Journal)
Source: Malaria Journal - July 13, 2018 Category: Infectious Diseases Authors: Ana Mar ía Vásquez, Lina Zuluaga, Alberto Tobón, Maritza Posada, Gabriel Vélez, Iveth J. González, Ana Campillo and Xavier Ding Tags: Research Source Type: research

Characterization of T cell activation and regulation in children with asymptomatic Plasmodium falciparum infection
Asymptomatic Plasmodium infections are characterized by the absence of clinical disease and the ability to restrict parasite replication. Increasing levels of regulatory T cells (Tregs) in Plasmodium falciparum i... (Source: Malaria Journal)
Source: Malaria Journal - July 13, 2018 Category: Infectious Diseases Authors: Augustina Frimpong, Kwadwo Asamoah Kusi, Bernard Tornyigah, Michael Fokuo Ofori and Wilfred Ndifon Tags: Research Source Type: research

Effectiveness and safety of 3 and 5 day courses of artemether –lumefantrine for the treatment of uncomplicated falciparum malaria in an area of emerging artemisinin resistance in Myanmar
Artemisinin resistance in Plasmodium falciparum has emerged and spread in Southeast Asia. In areas where resistance is established longer courses of artemisinin-based combination therapy have improved cure rates. (Source: Malaria Journal)
Source: Malaria Journal - July 11, 2018 Category: Infectious Diseases Authors: Kyaw Myo Tun, Atthanee Jeeyapant, Aung Hpone Myint, Zwe Thiha Kyaw, Mehul Dhorda, Mavuto Mukaka, Phaik Yeong Cheah, Mallika Imwong, Thaung Hlaing, Thar Htun Kyaw, Elizabeth A. Ashley, Arjen Dondorp, Nicholas J. White, Nicholas P. J. Day and Frank Smithuis Tags: Research Source Type: research

High efficacy of artemether –lumefantrine and dihydroartemisinin–piperaquine for the treatment of uncomplicated falciparum malaria in Muheza and Kigoma Districts, Tanzania
Artemether –lumefantrine (AL) is the recommended first-line artemisinin-based combination therapy (ACT) for the treatment of uncomplicated falciparum malaria in most of the malaria-endemic countries, including ... (Source: Malaria Journal)
Source: Malaria Journal - July 11, 2018 Category: Infectious Diseases Authors: Celine I. Mandara, Reginald A. Kavishe, Samuel Gesase, Janneth Mghamba, Esther Ngadaya, Peter Mmbuji, Sigsbert Mkude, Renata Mandike, Ritha Njau, Ally Mohamed, Martha M. Lemnge, Marian Warsame and Deus S. Ishengoma Tags: Research Source Type: research

Mapping the stability of malaria hotspots in Bangladesh from 2013 to 2016
Malaria claims hundreds of thousands of lives each year, most of them children. A “malaria-free world” is the World Health Organization’s vision, but elimination from the southeast Asian Region is hampered by ... (Source: Malaria Journal)
Source: Malaria Journal - July 11, 2018 Category: Infectious Diseases Authors: Andr és Noé, Sazid Ibna Zaman, Mosiqure Rahman, Anjan Kumar Saha, M. M. Aktaruzzaman and Richard James Maude Tags: Research Source Type: research

Malaria and the ‘last’ parasite: how can technology help?
Malaria, together with HIV/AIDS, tuberculosis and hepatitis are the four most deadly infectious diseases globally. Progress in eliminating malaria has saved millions of lives, but also creates new challenges i... (Source: Malaria Journal)
Source: Malaria Journal - July 11, 2018 Category: Infectious Diseases Authors: Ngoc Minh Pham, Walter Karlen, Hans-Peter Beck and Emmanuel Delamarche Tags: Review Source Type: research

Evaluation of loop-mediated isothermal amplification as a surveillance tool for malaria in reactive case detection moving towards elimination
As malaria transmission decreases, the proportion of infections that are asymptomatic at any given time increases. This poses a challenge for diagnosis as routinely used rapid diagnostic tests (RDTs) miss asym... (Source: Malaria Journal)
Source: Malaria Journal - July 9, 2018 Category: Infectious Diseases Authors: Munyaradzi Tambo, Joyce R. Auala, Hugh J. Sturrock, Immo Kleinschmidt, Ronnie Bock, Jennifer L. Smith, Roland Gosling and Davis R. Mumbengegwi Tags: Research Source Type: research

Evolution of host preference in anthropophilic mosquitoes
Insecticide-treated bed nets (ITNs) have played a large role in reducing the burden of malaria. There is concern however regarding the potential of the mass distributions and use of ITNs to select for insectic... (Source: Malaria Journal)
Source: Malaria Journal - July 9, 2018 Category: Infectious Diseases Authors: Chris Stone and Kevin Gross Tags: Research Source Type: research

Evidence for histidine-rich protein 2 immune complex formation in symptomatic patients in Southern Zambia
Rapid diagnostic tests based on histidine-rich protein 2 (HRP2) detection are the primary tools used to detect Plasmodium falciparum malaria infections. Recent conflicting reports call into question whether α-HRP... (Source: Malaria Journal)
Source: Malaria Journal - July 9, 2018 Category: Infectious Diseases Authors: Christine F. Markwalter, Lwiindi Mudenda, Mindy Leelawong, Danielle W. Kimmel, Armin Nourani, Saidon Mbambara, Philip E. Thuma and David W. Wright Tags: Research Source Type: research

Planning and implementation of a countrywide campaign to deliver over 16 million long-lasting insecticidal nets in Mozambique
In 2016/2017, Mozambique conducted a countrywide long-lasting insecticidal nets (LLINs) universal coverage campaign (UCC). This paper aims to describe the planning and implementation process of the campaign in... (Source: Malaria Journal)
Source: Malaria Journal - July 9, 2018 Category: Infectious Diseases Authors: Jorge A. H. Arroz, Baltazar Candrinho, S ílvia Pedro, Guidion Mathe, Mariana da Silva, Sérgio Tsabete, Luis Ismael, Inês Juleca, Marta Chande, Fernando Bambo, Olinda Munguande, Sérgio Julane, Figueiredo Mussambala, Eunice Alfai, Olimpia Muianga, Herme Tags: Research Source Type: research

Intermittent screening and treatment with artemether –lumefantrine versus intermittent preventive treatment with sulfadoxine–pyrimethamine for malaria in pregnancy: a facility-based, open-label, non-inferiority trial in Nigeria
The spread of SP resistance may compromise the effectiveness of intermittent preventive treatment of malaria in pregnancy (MiP) with sulfadoxine –pyrimethamine (IPTp-SP) across Africa. However, there is no reco... (Source: Malaria Journal)
Source: Malaria Journal - July 6, 2018 Category: Infectious Diseases Authors: Ekpereonne Esu, Nicole Berens-Riha, Michael Pritsch, Nuria Nwachuku, Thomas Loescher and Martin Meremikwu Tags: Research Source Type: research

Haemolysis and haem oxygenase-1 induction during persistent “asymptomatic” malaria infection in Burkinabé children
The haemolysis associated with clinical episodes of malaria results in the liberation of haem, which activates the enzyme haem oxygenase-1 (HO-1). HO-1 has been shown to reduce neutrophil function and increase... (Source: Malaria Journal)
Source: Malaria Journal - July 6, 2018 Category: Infectious Diseases Authors: Jason P. Mooney, Aissata Barry, Bronner P. Gon çalves, Alfred B. Tiono, Shehu S. Awandu, Lynn Grignard, Chris J. Drakeley, Christian Bottomley, Teun Bousema and Eleanor M. Riley Tags: Research Source Type: research

Trends of Plasmodium falciparum prevalence in two communities of Muheza district North-eastern Tanzania: correlation between parasite prevalence, malaria interventions and rainfall in the context of re-emergence of malaria after two decades of progressively declining transmission
Although the recent decline of malaria burden in some African countries has been attributed to a scale-up of interventions, such as bed nets (insecticide-treated bed nets, ITNs/long-lasting insecticidal nets, ... (Source: Malaria Journal)
Source: Malaria Journal - July 6, 2018 Category: Infectious Diseases Authors: Deus S. Ishengoma, Bruno P. Mmbando, Celine I. Mandara, Mercy G. Chiduo, Filbert Francis, Wilbert Timiza, Hellen Msemo, Agnes Kijazi, Martha M. Lemnge, Mwelecele N. Malecela, Robert W. Snow, Michael Alifrangis and Ib C. Bygbjerg Tags: Research Source Type: research