Structure –activity relationships in a series of antiplasmodial thieno[2,3-b]pyridines
Malaria is one of the most prevalent tropical infectious diseases. Since recently cases of artemisinin resistance were reported, novel anti-malarial drugs are required which differ from artemisinins in structu... (Source: Malaria Journal)
Source: Malaria Journal - March 21, 2019 Category: Infectious Diseases Authors: Andreas Masch, Abed Nasereddin, Arne Alder, Megan J. Bird, Sandra I. Schweda, Lutz Preu, Christian Doerig, Ron Dzikowski, Tim W. Gilberger and Conrad Kunick Tags: Research Source Type: research

Efficacy and safety of artemether-lumefantrine for the treatment of uncomplicated malaria and prevalence of Pfk13 and Pfmdr1 polymorphisms after a decade of using artemisinin-based combination therapy in mainland Tanzania
The World Health Organization recommends regular therapeutic efficacy studies (TES) to monitor the performance of first and second-line anti-malarials. In 2016, efficacy and safety of artemether-lumefantrine (... (Source: Malaria Journal)
Source: Malaria Journal - March 21, 2019 Category: Infectious Diseases Authors: Deus S. Ishengoma, Celine I. Mandara, Filbert Francis, Eldin Talundzic, Naomi W. Lucchi, Billy Ngasala, Abdunoor M. Kabanywanyi, Muhidin K. Mahende, Erasmus Kamugisha, Reginald A. Kavishe, Florida Muro, Ally Mohamed, Renata Mandike, Sigsbert Mkude, Frank Tags: Research Source Type: research

Evaluation of a push –pull system consisting of transfluthrin-treated eave ribbons and odour-baited traps for control of indoor- and outdoor-biting malaria vectors
Push –pull strategies have been proposed as options to complement primary malaria prevention tools, indoor residual spraying (IRS) and long-lasting insecticide-treated nets (LLINs), by targeting particularly ea... (Source: Malaria Journal)
Source: Malaria Journal - March 20, 2019 Category: Infectious Diseases Authors: Arnold S. Mmbando, Elis P. A. Batista, Masoud Kilalangongono, Marceline F. Finda, Emmanuel P. Mwanga, Emmanuel W. Kaindoa, Khamis Kifungo, Rukiyah M. Njalambaha, Halfan S. Ngowo, Alvaro E. Eiras and Fredros O. Okumu Tags: Research Source Type: research

Detection of Plasmodium falciparum infected Anopheles gambiae using near-infrared spectroscopy
Large-scale surveillance of mosquito populations is crucial to assess the intensity of vector-borne disease transmission and the impact of control interventions. However, there is a lack of accurate, cost-effe... (Source: Malaria Journal)
Source: Malaria Journal - March 19, 2019 Category: Infectious Diseases Authors: Marta F. Maia, Melissa Kapulu, Michelle Muthui, Martin G. Wagah, Heather M. Ferguson, Floyd E. Dowell, Francesco Baldini and Lisa-Ranford Cartwright Tags: Methodology Source Type: research

Short-term metabolic adjustments in Plasmodium falciparum counter hypoxanthine deprivation at the expense of long-term viability
The malarial parasite Plasmodium falciparum is an auxotroph for purines, which are required for nucleic acid synthesis during the intra-erythrocytic developmental cycle (IDC) of the parasite. The capabilities of ... (Source: Malaria Journal)
Source: Malaria Journal - March 19, 2019 Category: Infectious Diseases Authors: Shivendra G. Tewari, Krithika Rajaram, Patric Schyman, Russell Swift, Jaques Reifman, Sean T. Prigge and Anders Wallqvist Tags: Research Source Type: research

Mosquito electrocuting traps for directly measuring biting rates and host-preferences of Anopheles arabiensis and Anopheles funestus outdoors
Mosquito biting rates and host preferences are crucial determinants of human exposure to vector-borne diseases and the impact of vector control measures. The human landing catch (HLC) is a gold standard method... (Source: Malaria Journal)
Source: Malaria Journal - March 18, 2019 Category: Infectious Diseases Authors: Felician C. Meza, Katharina S. Kreppel, Deodatus F. Maliti, Amos T. Mlwale, Nosrat Mirzai, Gerry F. Killeen, Heather M. Ferguson and Nicodem J. Govella Tags: Research Source Type: research

Comparison of msp genotyping and a 24 SNP molecular assay for differentiating Plasmodium falciparum recrudescence from reinfection
Current World Health Organization guidelines for conducting anti-malarial drug efficacy clinical trials recommend genotyping Plasmodium falciparum genes msp1 and msp2 to distinguish recrudescence from reinfection... (Source: Malaria Journal)
Source: Malaria Journal - March 18, 2019 Category: Infectious Diseases Authors: Joseph Fulakeza, Sarah McNitt, Jimmy Vareta, Alex Saidi, Godfrey Mvula, Terrie Taylor, Don P. Mathanga, Dylan S. Small, Jacek Skarbinski, Julie R. Gutman and Karl Seydel Tags: Research Source Type: research

Spatiotemporal patterns of malaria at cross-boundaries area in Menoreh Hills, Java, Indonesia
Comprehensive reports of malaria in Menoreh Hills, Central Java, Indonesia, a unique district cross-boundaries area under three districts and two provinces have been published previously. However, no study was... (Source: Malaria Journal)
Source: Malaria Journal - March 15, 2019 Category: Infectious Diseases Authors: Dwi Sarwani Sri Rejeki, Anis Fuad, Barandi Sapta Widartono, E. Elsa Herdiana Murhandarwati and Hari Kusnanto Tags: Research Source Type: research

Characterizing local-scale heterogeneity of malaria risk: a case study in Bunkpurugu-Yunyoo district in northern Ghana
Bayesian methods have been used to generate country-level and global maps of malaria prevalence. With increasing availability of detailed malaria surveillance data, these methodologies can also be used to ide... (Source: Malaria Journal)
Source: Malaria Journal - March 15, 2019 Category: Infectious Diseases Authors: Punam Amratia, Paul Psychas, Benjamin Abuaku, Collins Ahorlu, Justin Millar, Samuel Oppong, Kwadwo Koram and Denis Valle Tags: Research Source Type: research

Avian malaria alters the dynamics of blood feeding in Culex pipiens mosquitoes
Some Plasmodium species have the ability to modify the behaviour of their mosquito vectors. This is thought to be an adaptive strategy that maximizes the parasite ’s transmission. (Source: Malaria Journal)
Source: Malaria Journal - March 15, 2019 Category: Infectious Diseases Authors: St éphane Cornet, Antoine Nicot, Ana Rivero and Sylvain Gandon Tags: Research Source Type: research

The interaction between permethrin exposure and malaria infection affects the host-seeking behaviour of mosquitoes
Insecticide-treated bed nets (ITNs) help to control malaria by mechanically impeding the biting of mosquitoes, by repelling and irritating them and by killing them. In contrast to spatial repellency, irritancy... (Source: Malaria Journal)
Source: Malaria Journal - March 14, 2019 Category: Infectious Diseases Authors: Kevin Thi évent, Gaël Hauser, Obada Elaian and Jacob C. Koella Tags: Research Source Type: research

In vivo compartmental kinetics of Plasmodium falciparum histidine-rich protein II in the blood of humans and in BALB/c mice infected with a transgenic Plasmodium berghei parasite expressing histidine-rich protein II
The Plasmodium falciparum histidine-rich protein II (PfHRP2) is a common biomarker used in malaria rapid diagnostic tests (RDTs), but can persist in the blood for up to 40 days following curative treatment. The p... (Source: Malaria Journal)
Source: Malaria Journal - March 13, 2019 Category: Infectious Diseases Authors: Kristin E. Poti, Amanda E. Balaban, Priya Pal, Tamaki Kobayashi, Daniel E. Goldberg, Photini Sinnis and David J. Sullivan Tags: Research Source Type: research

Brain magnetic resonance imaging in imported malaria
Previous studies have documented a spectrum of brain magnetic resonance imaging (MRI) abnormalities in patients with cerebral malaria, but little is known about the prevalence of such abnormalities in patients... (Source: Malaria Journal)
Source: Malaria Journal - March 12, 2019 Category: Infectious Diseases Authors: Andreas M. Fr ölich, Pinkus Tober-Lau, Michael Schönfeld, Thomas T. Brehm, Florian Kurth, Christof D. Vinnemeier, Marylyn M. Addo, Jens Fiehler and Thierry Rolling Tags: Research Source Type: research

Longitudinal analysis of gamma delta T cell subsets during malaria infections in Malian adults
Immunity that limits malarial disease is acquired over time, but adults living in endemic areas continue to become infected and can require treatment for clinical illness. Gamma delta ( γδ) T cells, particularl... (Source: Malaria Journal)
Source: Malaria Journal - March 12, 2019 Category: Infectious Diseases Authors: Hama Diallo, Abdoulaye Katile, Jennifer L. Kwan, Mahamadou S. Sissoko, Sara A. Healy, Ogobara K. Doumbo, Patrick E. Duffy and Irfan Zaidi Tags: Research Source Type: research

A comparison of thick-film microscopy, rapid diagnostic test, and polymerase chain reaction for accurate diagnosis of Plasmodium falciparum malaria
Accurate diagnosis of malaria is important for effective disease management and control. In Cameroon, presumptive clinical diagnosis, thick-film microscopy (TFM), and rapid diagnostic tests (RDT) are commonly ... (Source: Malaria Journal)
Source: Malaria Journal - March 12, 2019 Category: Infectious Diseases Authors: Kenji O. Mfuh, Olivia A. Achonduh-Atijegbe, Obase N. Bekindaka, Livo F. Esemu, Calixt D. Mbakop, Krupa Gandhi, Rose G. F. Leke, Diane W. Taylor and Vivek R. Nerurkar Tags: Research Source Type: research

Prevalence of G6PD Viangchan variant in malaria endemic areas in Lao PDR: an implication for malaria elimination by 2030
Primaquine is effective against the latent liver stage of Plasmodium vivax. Eliminating the latent liver stage of P. vivax is one of the necessary conditions to achieve the goal of malaria elimination in Lao Peop... (Source: Malaria Journal)
Source: Malaria Journal - March 12, 2019 Category: Infectious Diseases Authors: Ken Ing Cherng Ong, Moritoshi Iwagami, Hitomi Araki, Phonepadith Khattignavong, Pheovaly Soundala, Sengdeuane Keomalaphet, Phoyphaylinh Prasayasith, Lavy Lorpachan, Phonepadith Xangsayalath, Tiengkham Pongvongsa, Bouasy Hongvanthong, Paul T. Brey, Shigeyu Tags: Research Source Type: research

Exploring the heterogeneity of human exposure to malaria vectors in an urban setting, Bouak é, Côte d’Ivoire, using an immuno-epidemiological biomarker
In some African cities, urban malaria is a threat to the health and welfare of city dwellers. To improve the control of the disease, it is critical to identify neighbourhoods where the risk of malaria transmis... (Source: Malaria Journal)
Source: Malaria Journal - March 11, 2019 Category: Infectious Diseases Authors: Dipomin F. Traor é, André B. Sagna, Akré M. Adja, Dounin D. Zoh, Kouassi A. Adou, Kouassi N. Lingué, Issa Coulibaly, N’Cho Bertin Tchiekoi, Serge B. Assi, Anne Poinsignon, Mamadou Dagnogo and Franck Remoue Tags: Research Source Type: research

Determinants of bed net use conditional on access in population surveys in Ghana
Insecticide-treated nets (ITNs) are one of the most effective and widely available methods for preventing malaria, and there is interest in understanding the complexities of behavioural drivers of non-use amon... (Source: Malaria Journal)
Source: Malaria Journal - March 8, 2019 Category: Infectious Diseases Authors: Emily Ricotta, Samuel Oppong, Joshua O. Yukich and Olivier J. T. Bri ët Tags: Research Source Type: research

Human population movement and behavioural patterns in malaria hotspots on the Thai –Myanmar border: implications for malaria elimination
Malaria is heterogeneously distributed across landscapes. Human population movement (HPM) could link sub-regions with varying levels of transmission, leading to the persistence of disease even in very low tran... (Source: Malaria Journal)
Source: Malaria Journal - March 8, 2019 Category: Infectious Diseases Authors: Sayambhu Saita, Wirichada Pan-ngum, Suparat Phuanukoonnon, Patchara Sriwichai, Tassanee Silawan, Lisa J. White and Daniel M. Parker Tags: Research Source Type: research

Bioassay-guided isolation and identification of gametocytocidal compounds from Artemisia afra (Asteraceae)
Optimal adoption of the malaria transmission-blocking strategy is currently limited by lack of safe and efficacious drugs. This has sparked the exploration of different sources of drugs in search of transmissi... (Source: Malaria Journal)
Source: Malaria Journal - March 8, 2019 Category: Infectious Diseases Authors: Phanankosi Moyo, Phaladi Kunyane, Mamoalosi A. Selepe, Jacobus N. Eloff, Jandeli Niemand, Abraham I. Louw, Vinesh J. Maharaj and Lyn-Marie Birkholtz Tags: Research Source Type: research

Defining the ecological and evolutionary drivers of Plasmodium knowlesi transmission within a multi-scale framework
Plasmodium knowlesi is a zoonotic malaria parasite normally residing in long-tailed and pig-tailed macaques (Macaca fascicularis and Macaca nemestrina, respectively) found throughout Southeast Asia. Recently, kno... (Source: Malaria Journal)
Source: Malaria Journal - March 8, 2019 Category: Infectious Diseases Authors: Gael Davidson, Tock H. Chua, Angus Cook, Peter Speldewinde and Philip Weinstein Tags: Review Source Type: research

K13-propeller gene polymorphisms in Plasmodium falciparum parasite population in malaria affected countries: a systematic review of prevalence and risk factors
Efficacy of artemisinin (ART) agents, a critical element of current malaria control efforts is threatened by emergence and spread of resistance. Mutations in pfkelch13 gene associated with ART-resistance evolved ... (Source: Malaria Journal)
Source: Malaria Journal - March 7, 2019 Category: Infectious Diseases Authors: Moses Ocan, Dickens Akena, Sam Nsobya, Moses R. Kamya, Richard Senono, Alison Annet Kinengyere and Ekwaro Obuku Tags: Research Source Type: research

Investigating the upsurge of malaria prevalence in Zambia between 2010 and 2015: a decomposition of determinants
Malaria is among the top causes of mortality and morbidity in Zambia. Efforts to control, prevent, and eliminate it have been intensified in the past two decades which has contributed to reductions in malaria ... (Source: Malaria Journal)
Source: Malaria Journal - March 7, 2019 Category: Infectious Diseases Authors: Mukumbuta Nawa, Peter Hangoma, Andrew P. Morse and Charles Michelo Tags: Research Source Type: research

UDP-glycosyltransferase genes and their association and mutations associated with pyrethroid resistance in Anopheles sinensis (Diptera: Culicidae)
UDP-glycosyltransferase (UGT) is an important biotransformation superfamily of enzymes. They catalyze the transfer of glycosyl residues from activated nucleotide sugars to acceptor hydrophobic molecules, and f... (Source: Malaria Journal)
Source: Malaria Journal - March 7, 2019 Category: Infectious Diseases Authors: Yong Zhou, Wen-Bo Fu, Feng-Ling Si, Zhen-Tian Yan, Yu-Juan Zhang, Qi-Yi He and Bin Chen Tags: Research Source Type: research

Evaluation of MAGNet, a long-lasting insecticidal mosquito net against Anopheles fluviatilis in experimental huts in India
MAGNet LN is a wash resistant long-lasting insecticidal (polyethylene) net (LLIN) in which the alpha-cypermethrin insecticide is incorporated within the 150 denier high density polyethylene monofilaments of th... (Source: Malaria Journal)
Source: Malaria Journal - March 6, 2019 Category: Infectious Diseases Authors: Gunasekaran Kasinathan, Sudhansu Sekhar Sahu, Vijayakumar Tharmalingam, Subramanian Swaminathan, Manju Rahi and Jambulingam Purushothaman Tags: Research Source Type: research

Acute interstitial nephritis with podocyte foot-process effacement complicating Plasmodium falciparum infection
Malarial acute renal failure (MARF) is a component of the severe malaria syndrome, and complicates 1 –5% of malaria infections. This form of renal failure has not been well characterized by histopathology. (Source: Malaria Journal)
Source: Malaria Journal - March 1, 2019 Category: Infectious Diseases Authors: Patrick J. Gleeson, John A. O ’Regan, Teresa McHale, Helen Tuite, Louise Giblin and Donal Reddan Tags: Case report Source Type: research

An update on glucose-6-phosphate dehydrogenase deficiency in children from Brazzaville, Republic of Congo
Malaria transmission-blocking anti-malarial drugs, such as primaquine, offers an effective strategy for reducing the incidence of falciparum malaria. However, this drug induces haemolytic anaemia among glucose... (Source: Malaria Journal)
Source: Malaria Journal - February 28, 2019 Category: Infectious Diseases Authors: Nerly Shir ère Gampio Gueye, Simon Marie Peko, David Nderu, Felix Koukouikila-Koussounda, Christevy Vouvoungui, Simon Charles Kobawila, Thirumalaisamy P. Velavan and Francine Ntoumi Tags: Research Source Type: research

Environmental and sociodemographic factors associated with household malaria burden in the Congo
This study aimed to determine the scope of household, ac... (Source: Malaria Journal)
Source: Malaria Journal - February 26, 2019 Category: Infectious Diseases Authors: Nlandu Roger Ngatu, Sakiko Kanbara, Andre Renzaho, Roger Wumba, Etongola P. Mbelambela, Sifa M. J. Muchanga, Basilua Andre Muzembo, Ngombe Leon-Kabamba, Choomplang Nattadech, Tomoko Suzuki, Numbi Oscar-Luboya, Koji Wada, Mitsunori Ikeda, Sayumi Nojima, To Tags: Research Source Type: research

Environmental and meteorological factors linked to malaria transmission around large dams at three ecological settings in Ethiopia
A growing body of evidence suggests that dams intensify malaria transmission in sub-Saharan Africa. However, the environmental characteristics underpinning patterns in malaria transmission around dams are poor... (Source: Malaria Journal)
Source: Malaria Journal - February 26, 2019 Category: Infectious Diseases Authors: Solomon Kibret, G. Glenn Wilson, Darren Ryder, Habte Tekie and Beyene Petros Tags: Research Source Type: research

Impact of sunlight exposure on the residual efficacy of biolarvicides Bacillus thuringiensis israelensis and Bacillus sphaericus against the main malaria vector, Anopheles gambiae
Biotic and abiotic factors have been reported to affect the larvicidal efficacy of Bacillus thuringiensis israelensis (Bti) and Bacillus sphaericus (Bs), although the extent to which they are affected has been po... (Source: Malaria Journal)
Source: Malaria Journal - February 26, 2019 Category: Infectious Diseases Authors: Barnabas Zogo, Bertin N ’Cho Tchiekoi, Alphonsine A. Koffi, Amal Dahounto, Ludovic P. Ahoua Alou, Roch K. Dabiré, Lamine Baba-Moussa, Nicolas Moiroux and Cédric Pennetier Tags: Research Source Type: research

‘The mosquitoes are preparing to attack us’: knowledge and perceptions of communities in south-eastern Tanzania regarding mosquito swarms
Targeting swarms of male Anopheles mosquitoes with techniques such as aerosol spraying could potentially suppress malaria vector populations and parasite transmission. Unfortunately, research on Anopheles swarmin... (Source: Malaria Journal)
Source: Malaria Journal - February 26, 2019 Category: Infectious Diseases Authors: Marceline F. Finda, Emmanuel W. Kaindoa, Anna P. Nyoni and Fredros O. Okumu Tags: Research Source Type: research

The impact of Anopheles gambiae egg storage for mass rearing and production success
Mass rearing requires a large colony from which male individuals can be harvested for sterilization and release. Attention is needed when monitoring life parameters of the reared population, knowing that any v... (Source: Malaria Journal)
Source: Malaria Journal - February 26, 2019 Category: Infectious Diseases Authors: Ernest Mazigo, Winifrida Kidima, Joseph Myamba and Eliningaya J. Kweka Tags: Methodology Source Type: research

Evaluation of toxicity of clothianidin (neonicotinoid) and chlorfenapyr (pyrrole) insecticides and cross-resistance to other public health insecticides in Anopheles arabiensis from Ethiopia
Insecticide-based interventions play an integral role in malaria vector control. However, the continued spread of insecticide resistance threatens to undermine progress made thus far and may ultimately lead to... (Source: Malaria Journal)
Source: Malaria Journal - February 22, 2019 Category: Infectious Diseases Authors: Kendra Dagg, Seth Irish, Ryan E. Wiegand, Josephat Shililu, Delenasaw Yewhalaw and Louisa A. Messenger Tags: Research Source Type: research

The role of monitoring and evaluation to ensure functional access to community-based early diagnosis and treatment in a malaria elimination programme in Eastern Myanmar
Improving access to early diagnosis and treatment (EDT) has increasingly proven to be a major contributor to decreasing malaria incidence in low-transmission settings. The Malaria Elimination Task Force (METF)... (Source: Malaria Journal)
Source: Malaria Journal - February 22, 2019 Category: Infectious Diseases Authors: Jade D. Rae, Suphak Nosten, St éphane Proux, Aung Myint Thu, Win Cho Cho, K’Nyaw Paw, Eh Shee Paw, Paw Bway Shee, Saw Aye Be, Saw Hsa Dah, Saw Ku Ler Moo, Saw Myo Chit Minh, Paw Wah Shee, Jacher Wiladphaingern, Saw Win Tun, Ladda Kajeechiwa & hellip; Tags: Research Source Type: research

Assessment of the Suna trap for sampling mosquitoes indoors and outdoors
Entomological monitoring is important for public health because it provides data on the distribution, abundance and host-seeking behaviour of disease vectors. Various methods for sampling mosquitoes exist, mos... (Source: Malaria Journal)
Source: Malaria Journal - February 22, 2019 Category: Infectious Diseases Authors: Monicah M. Mburu, Kennedy Zembere, Alexandra Hiscox, Jomo Banda, Kamija S. Phiri, Henk van den Berg, Themba Mzilahowa, Willem Takken and Robert S. McCann Tags: Research Source Type: research

Effects and factors associated with indoor residual spraying with Actellic 300 CS on malaria morbidity in Lira District, Northern Uganda
Indoor residual spraying (IRS) with Actellic 300 CS was conducted in Lira District between July and August 2016. No formal assessment has been conducted to estimate the effect of spraying with Actellic 300 CS ... (Source: Malaria Journal)
Source: Malaria Journal - February 21, 2019 Category: Infectious Diseases Authors: Abdulaziz Tugume, Fiston Muneza, Frederick Oporia, Arthur Kiconco, Christine Kihembo, Angela Nakanwagi Kisakye, Peter Nsubuga, Sekimpi Deogratias and Adoke Yeka Tags: Research Source Type: research

Effectiveness of 24-h mobile reporting tool during a malaria outbreak in Mpumalanga Province, South Africa
As surveillance is a key strategy for malaria elimination in South Africa, ensuring strong surveillance systems is a National Department of Health priority. Historically, real time tracking of case trends and ... (Source: Malaria Journal)
Source: Malaria Journal - February 21, 2019 Category: Infectious Diseases Authors: Craig Davies, Rebecca Graffy, Mbavhalelo Shandukani, Ednah Baloyi, Laura Gast, Gerdalize Kok, Frans Mbokazi, Alpheus Zita, Mandla Zwane, Ray Magagula, Aaron Mabuza, Wayne Ramkrishna, Natashia Morris, Jacqueline Porteous, George Shirreff, Lucille Blumberg Tags: Research Source Type: research

On the discriminatory and predictive accuracy of the RDT against the microscopy in the diagnosis of malaria among under-five children in Nigeria
This study is designed to evaluate the discriminatory and predictive accur... (Source: Malaria Journal)
Source: Malaria Journal - February 21, 2019 Category: Infectious Diseases Authors: Adeniyi Francis Fagbamigbe Tags: Research Source Type: research

Malaria case management commodity supply and use by community health workers in Mozambique, 2017
Community health workers (CHWs) provide preventive care and integrated community case management (iCCM) to people with low healthcare access worldwide. CHW programmes have helped reduce mortality in myriad cou... (Source: Malaria Journal)
Source: Malaria Journal - February 21, 2019 Category: Infectious Diseases Authors: Elizabeth Davlantes, Cristolde Salomao, Flavio Wate, Deonilde Sarmento, Humberto Rodrigues, Eric S. Halsey, Lauren Lewis, Baltazar Candrinho and Rose Zulliger Tags: Research Source Type: research

Association of high Plasmodium falciparum parasite densities with polyclonal microscopic infections in asymptomatic children from Toubacouta, Senegal
Malaria is a leading cause of mortality and morbidity in tropical countries, especially in sub-Saharan Africa. In Senegal, a control plan implemented in the beginning of the 2000s has enabled a substantial red... (Source: Malaria Journal)
Source: Malaria Journal - February 21, 2019 Category: Infectious Diseases Authors: Babacar Diouf, Fode Diop, Yakhya Dieye, Cheikh Loucoubar, Ibrahima Dia, Joseph Faye, Mback é Sembène, Ronald Perraut, Makhtar Niang and Aïssatou Toure-Balde Tags: Research Source Type: research

Effects of a health educational intervention on malaria knowledge, motivation, and behavioural skills: a randomized controlled trial
The levels of insecticide-treated net use among pregnant women and uptake of intermittent preventive treatment in pregnancy, have been sub-optimal in Nigeria. Previous studies have reported positive correlatio... (Source: Malaria Journal)
Source: Malaria Journal - February 20, 2019 Category: Infectious Diseases Authors: Ahmed Dahiru Balami, Salmiah Md Said, Nor Afiah Mohd Zulkefli, Norsa ’adah Bachok and Bala Audu Tags: Research Source Type: research

Factors associated with children ’s health facility visits for primaquine treatment in rural Papua New Guinea
To control and eventually eliminate vivax malaria, radical treatment with primaquine (PQ) is essential after completion of blood-stage treatment. Although in many malaria-endemic countries, village health volu... (Source: Malaria Journal)
Source: Malaria Journal - February 20, 2019 Category: Infectious Diseases Authors: Akiko Yoshii, Makoto Sekihara, Takuro Furusawa, Francis Hombhanje and Takahiro Tsukahara Tags: Research Source Type: research

A comparative study of the prevalence of and factors associated with insecticide-treated nets usage among children under 5 years of age in households that already own nets in Malawi
Despite malaria control programmes having successfully increased the number of households owning insecticide-treated nets (ITNs) in Malawi, the population of people with ITN access but still not using them flu... (Source: Malaria Journal)
Source: Malaria Journal - February 20, 2019 Category: Infectious Diseases Authors: Owen Nkoka, Martha Sinya Chipeta, Ying-Chih Chuang, Deleon Fergus and Kun-Yang Chuang Tags: Research Source Type: research

Relationship between weight status and anti-malarial drug efficacy and safety in children in Mali
Anti-malarial treatments effectiveness remains a critical challenge for control programmes. However, when drug efficacy is established, the dose is calculated based on a predefined weight according to the pati... (Source: Malaria Journal)
Source: Malaria Journal - February 18, 2019 Category: Infectious Diseases Authors: Moussa Djimde, Hanen Samouda, Julien Jacobs, Hamidou Niangaly, Mamadou Tekete, Seydou B. Sombie, Erick Josephat Mgina, Bakary Fofana, Issaka Sagara, Ogobara K. Doumbo, Michel Vaillant and Abdoulaye A. Djimde Tags: Research Source Type: research

Community perspectives on treating asymptomatic infections for malaria elimination in The Gambia
Innovative and cost-effective strategies that clear asymptomatic malaria infections are required to reach malaria elimination goals, but remain a challenge. This mixed methods study explored people ’s attitudes... (Source: Malaria Journal)
Source: Malaria Journal - February 18, 2019 Category: Infectious Diseases Authors: Fatou Jaiteh, Yoriko Masunaga, Joseph Okebe, Umberto D ’Alessandro, Julie Balen, John Bradley, Charlotte Gryseels, Joan Muela Ribera and Koen Peeters Grietens Tags: Research Source Type: research

Updating the modified Thompson test by using whole-body bioluminescence imaging to replace traditional efficacy testing in experimental models of murine malaria
Rodent malaria models are extensively used to predict treatment outcomes in human infections. There is a constant need to improve and refine these models by innovating ways to apply new scientific findings and... (Source: Malaria Journal)
Source: Malaria Journal - February 15, 2019 Category: Infectious Diseases Authors: Diana Caridha, Mark Hickman, Lisa Xie, Franklyn Ngundam, Erin Milner, Amanda Schenk, Kirk Butler, Dylan Nugent, Patricia Lee, Norma Roncal, Susan Leed, Eve Hosford, Jangwoo Lee, Richard J. Sciotti, Gregory Reichard, Chad Black & hellip; Tags: Methodology Source Type: research

Implications of insecticide resistance for malaria vector control with long-lasting insecticidal nets: evidence from health facility data from Benin
This study investigat... (Source: Malaria Journal)
Source: Malaria Journal - February 11, 2019 Category: Infectious Diseases Authors: Fil émon T. Tokponnon, Yolande Sissinto, Aurore Hounto Ogouyémi, Adicath Adéola Adéothy, Alioun Adechoubou, Télesphore Houansou, Mariam Oke, Dorothée Kinde-Gazard, Achille Massougbodji, Martin C. Akogbeto, Sylvie Cornelie, Vincent Corbel, Tessa B. K Tags: Research Source Type: research

Prescribing patterns and compliance with World Health Organization recommendations for the management of severe malaria: a modified cohort event monitoring study in public health facilities in Ghana and Uganda
Injectable artesunate (AS) is the World Health Organization (WHO) recommended medication for the treatment of severe malaria followed with an oral artemisinin-based combination therapy (ACT). There are few stu... (Source: Malaria Journal)
Source: Malaria Journal - February 8, 2019 Category: Infectious Diseases Authors: H. Hilda Ampadu, Kwaku Poku Asante, Samuel Bosomprah, Samantha Akakpo, Pierre Hugo, Helga Gardarsdottir, Hubert G. M. Leufkens, Dan Kajungu and Alexander N. O. Dodoo Tags: Research Source Type: research

Effects of Azadirachta indica seed kernel extracts on early erythrocytic schizogony of Plasmodium berghei and pro-inflammatory response in inbred mice
Medicinal plant research may contribute to develop new pharmacological control tools for vector borne diseases, such as malaria. (Source: Malaria Journal)
Source: Malaria Journal - February 8, 2019 Category: Infectious Diseases Authors: Annette Habluetzel, Barbara Pinto, Sofia Tapanelli, Judith Nkouangang, Michela Saviozzi, Giuseppina Chianese, Annalisa Lopatriello, Alain Rodrigue Tenoh, Rakiswend é Serge Yerbanga, Orazio Taglialatela-Scafati, Fulvio Esposito and Fabrizio Bruschi Tags: Research Source Type: research

Aminoacyl tRNA synthetases as malarial drug targets: a comparative bioinformatics study
Treatment of parasitic diseases has been challenging due to evolution of drug resistant parasites, and thus there is need to identify new class of drugs and drug targets. Protein translation is important for s... (Source: Malaria Journal)
Source: Malaria Journal - February 6, 2019 Category: Infectious Diseases Authors: Dorothy Wavinya Nyamai and Özlem Tastan Bishop Tags: Research Source Type: research