Late clinical failure associated with cytochrome b codon 268 mutation during treatment of falciparum malaria with atovaquone –proguanil in traveller returning from Congo
The drug combination atovaquone –proguanil, is recommended for treatment of uncomplicated falciparum malaria in France. Despite high efficacy, atovaquone–proguanil treatment failures have been reported. Resista... (Source: Malaria Journal)
Source: Malaria Journal - January 21, 2020 Category: Infectious Diseases Authors: Laurencie Massamba, Marylin Madamet, Nicolas Benoit, Alicia Chevalier, Isabelle Fonta, V éronique Mondain, Pierre-Yves Jeandel, Rémy Amalvict, Pascal Delaunay, Joel Mosnier, Pierre Marty, Christelle Pomares and Bruno Pradines Tags: Case report Source Type: research

Molecular characteristics of odorant-binding protein 1 in Anopheles maculipennis
Anopheles maculipennis complex, the historic vector of malaria, causes serious medical problems worldwide and exhibits different behaviours. Studying the odorant-binding proteins (OBPs), which influence the chemo... (Source: Malaria Journal)
Source: Malaria Journal - January 17, 2020 Category: Infectious Diseases Authors: Mohammad Bagher Ghavami, Sakineh Khoeini and Navid Dinparast Djadid Tags: Research Source Type: research

‘We spray and walk away’: wall modifications decrease the impact of indoor residual spray campaigns through reductions in post-spray coverage
Malaria prevalence has significantly reduced since 2000, largely due to the scale-up of vector control interventions, mainly indoor residual spraying (IRS) and long-lasting insecticide-treated nets (LLINs). Gi... (Source: Malaria Journal)
Source: Malaria Journal - January 17, 2020 Category: Infectious Diseases Authors: Mercy A. Opiyo and Krijn P. Paaijmans Tags: Opinion Source Type: research

A panel of recombinant proteins from human-infective Plasmodium species for serological surveillance
Malaria remains a global health problem and accurate surveillance of Plasmodium parasites that are responsible for this disease is required to guide the most effective distribution of control measures. Serologica... (Source: Malaria Journal)
Source: Malaria Journal - January 17, 2020 Category: Infectious Diseases Authors: Nicole M üller-Sienerth, Jarrod Shilts, Khamisah Abdul Kadir, Victor Yman, Manijeh Vafa Homann, Muhammad Asghar, Billy Ngasala, Balbir Singh, Anna Färnert and Gavin J. Wright Tags: Methodology Source Type: research

Use of a highly-sensitive rapid diagnostic test to screen for malaria in pregnancy in Indonesia
The sensitivity of rapid diagnostic tests (RDTs) for malaria is inadequate for detecting low-density, often asymptomatic infections, such as those that can occur when screening pregnant women for malaria. The ... (Source: Malaria Journal)
Source: Malaria Journal - January 16, 2020 Category: Infectious Diseases Authors: Vera T. Unwin, Rukhsana Ahmed, Rintis Noviyanti, Agatha M. Puspitasari, Retno A. S. Utami, Leily Trianty, Theda Lukito, Din Syafruddin, Jeanne R. Poespoprodjo, Maria A. Santana-Morales, Feiko O. Ter Kuile and Emily R. Adams Tags: Research Source Type: research

Associations between red blood cell variants and malaria among children and adults from three areas of Uganda: a prospective cohort study
Multiple red blood cell (RBC) variants appear to offer protection against the most severe forms of Plasmodium falciparum malaria. Associations between these variants and uncomplicated malaria are less clear. (Source: Malaria Journal)
Source: Malaria Journal - January 15, 2020 Category: Infectious Diseases Authors: Elijah Kakande, Bryan Greenhouse, Francis Bajunirwe, Chris Drakeley, Joaniter I. Nankabirwa, Andrew Walakira, Samuel L. Nsobya, Agaba Katureebe, John Rek, Emmanuel Arinaitwe, Philip J. Rosenthal, Moses R. Kamya, Grant Dorsey and Isabel Rodriguez-Barraquer Tags: Research Source Type: research

Preferred resting surfaces of dominant malaria vectors inside different house types in rural south-eastern Tanzania
Malaria control in Africa relies extensively on indoor residual spraying (IRS) and insecticide-treated nets (ITNs). IRS typically targets mosquitoes resting on walls, and in few cases, roofs and ceilings, usin... (Source: Malaria Journal)
Source: Malaria Journal - January 15, 2020 Category: Infectious Diseases Authors: Betwel J. Msugupakulya, Emmanuel W. Kaindoa, Halfan S. Ngowo, Japhet M. Kihonda, Najat F. Kahamba, Dickson S. Msaky, Damaris Matoke-Muhia, Patrick K. Tungu and Fredros O. Okumu Tags: Research Source Type: research

RDL mutations in Guangxi Anopheles sinensis populations along the China –Vietnam border: distribution frequency and evolutionary origin of A296S resistance allele
Malaria is a deadly vector-borne disease in tropical and subtropical regions. Although indigenous malaria has been eliminated in Guangxi of China, 473 confirmed cases were reported in the Northern region of ne... (Source: Malaria Journal)
Source: Malaria Journal - January 15, 2020 Category: Infectious Diseases Authors: Nian Liu, Xiangyang Feng and Xinghui Qiu Tags: Research Source Type: research

Exploring association between MBL2 gene polymorphisms and the occurrence of clinical blackwater fever through a case –control study in Congolese children
Blackwater fever (BWF), one of the most severe and life-threatening forms of falciparum malaria, is characterized by acute massive intravascular haemolysis, often leading to acute renal failure. Thus far, the ... (Source: Malaria Journal)
Source: Malaria Journal - January 15, 2020 Category: Infectious Diseases Authors: Joseph M. Bodi, C élestin N. Nsibu, Roland L. Longenge, Michel N. Aloni, Pierre Z. Akilimali, Patrick K. Kayembe, Ahmeddin H. Omar, Jan Verhaegen, Pierre M. Tshibassu, Prosper T. Lukusa, Aimé Lumaka and Kenji Hirayama Tags: Research Source Type: research

Resistance status of Anopheles gambiae s.l. to insecticides following the 2011 mass distribution campaign of long-lasting insecticidal nets (LLINs) in the Plateau Department, south-eastern Benin
In 2011, Benin ’s National Malaria Control Programme (NMCP) organized a nationwide mass distribution campaign of LLINs throughout the country. Following this intervention, it was important to assess whether the... (Source: Malaria Journal)
Source: Malaria Journal - January 15, 2020 Category: Infectious Diseases Authors: Arthur Sovi, Renaud Govo étchan, Razaki Ossé, Come Z. Koukpo, Albert S. Salako, Thomas Syme, Rodrigue Anagonou, Augustin Fongnikin, Udoka C. Nwangwu, Frédéric Oké-Agbo, Filémon Tokponnon, Gil Germain Padonou and Martin Codjo Akogbeto Tags: Research Source Type: research

Testing possible causes of gametocyte reduction in temporally out-of-synch malaria infections
The intraerythrocytic development cycle (IDC) of the rodent malaria Plasmodium chabaudi is coordinated with host circadian rhythms. When this coordination is disrupted, parasites suffer a 50% reduction in both as... (Source: Malaria Journal)
Source: Malaria Journal - January 14, 2020 Category: Infectious Diseases Authors: Mary L. Westwood, Aidan J. O ’Donnell, Petra Schneider, Gregory F. Albery, Kimberley F. Prior and Sarah E. Reece Tags: Research Source Type: research

Unlicensed medical practitioners in tribal dominated rural areas of central India: bottleneck in malaria elimination
In India, Accredited Social Health Activists (ASHAs) deliver services for diagnosis and treatment of malaria, although unlicensed medical practitioners (UMPs) (informal health providers) are most preferred in ... (Source: Malaria Journal)
Source: Malaria Journal - January 14, 2020 Category: Infectious Diseases Authors: Mrigendra Pal Singh, Sunil Kumar Chand, Kalyan Brata Saha, Neetiraj Singh, Ramesh C. Dhiman and Lora L. Sabin Tags: Research Source Type: research

Evaluation of long-lasting indoor residual spraying of deltamethrin 62.5 SC-PE against malaria vectors in India
Deltamethrin 62.5 polymer-enhanced suspension concentrate (SC-PE) is one of the World Health Organization-approved insecticides for indoor residual spraying and was recommended to evaluate its residual activit... (Source: Malaria Journal)
Source: Malaria Journal - January 14, 2020 Category: Infectious Diseases Authors: Sudhansu Sekhar Sahu, Sonia Thankachy, Smrutidhara Dash, Krishnamoorthy Nallan, Subramanian Swaminathan, Gunasekaran Kasinathan and Jambulingam Purushothaman Tags: Research Source Type: research

Willingness-to-pay for long-lasting insecticide-treated bed nets: a discrete choice experiment with real payment in Ghana
Expanding access to long-lasting insecticidal nets (LLINs) is difficult if one is limited to government and donor financial resources. Private commercial markets could play a larger role in the continuous dist... (Source: Malaria Journal)
Source: Malaria Journal - January 13, 2020 Category: Infectious Diseases Authors: Y. Natalia Alfonso, Matthew Lynch, Elorm Mensah, Danielle Piccinini and David Bishai Tags: Research Source Type: research

Analysis of anti-Plasmodium IgG profiles among Fulani nomadic pastoralists in northern Senegal to assess malaria exposure
Northern Senegal is a zone of very low malaria transmission, with an annual incidence of (Source: Malaria Journal)
Source: Malaria Journal - January 13, 2020 Category: Infectious Diseases Authors: Mame Cheikh Seck, Julie Thwing, Aida Sadikh Badiane, Eric Rogier, Fatou Ba Fall, Pape Ibrahima Ndiaye, Khadim Diongue, Moustapha Mbow, Mouhamadou Ndiaye, Mamadou Alpha Diallo, Jules Fran çois Gomis, Aminata Mbaye, Tolla Ndiaye, Aminata Gaye, Mohamad Sy, Tags: Research Source Type: research

A systematic review of factors affecting adherence to malaria chemoprophylaxis amongst travellers from non-endemic countries
The aim of this systematic review was to identify predictors of actual or intended adherence with malaria chemoprophylaxis amongst travellers from non-endemic countries visiting endemic countries. (Source: Malaria Journal)
Source: Malaria Journal - January 13, 2020 Category: Infectious Diseases Authors: Julian Ahluwalia, Samantha K. Brooks, John Weinman and G. James Rubin Tags: Research Source Type: research

Quantification of malaria antigens PfHRP2 and pLDH by quantitative suspension array technology in whole blood, dried blood spot and plasma
Malaria diagnostics by rapid diagnostic test (RDT) relies primarily on the qualitative detection of Plasmodium falciparum histidine-rich protein 2 (PfHRP2) and Plasmodium spp lactate dehydrogenase (pLDH). As nove... (Source: Malaria Journal)
Source: Malaria Journal - January 9, 2020 Category: Infectious Diseases Authors: Xavier Marti áñez-Vendrell, Alfons Jiménez, Ana Vásquez, Ana Campillo, Sandra Incardona, Raquel González, Dionicia Gamboa, Katherine Torres, Wellington Oyibo, Babacar Faye, Eusebio Macete, Clara Menéndez, Xavier C. Ding and Alfredo Mayor Tags: Methodology Source Type: research

Update to: A stakeholder workshop about modelled maps of key malaria indicator survey indicators in Madagascar
(Source: Malaria Journal)
Source: Malaria Journal - January 9, 2020 Category: Infectious Diseases Authors: Rosalind E. Howes, Kaleem Hawa, Voahangy Fanomezana Andriamamonjy, Thierry Franchard, Raharizo Miarimbola, Sedera Aur élien Mioramalala, Jean Florent Rafamatanantsoa, Mirana Ando Mbolatiana Rahantamalala, Solo Harimalala Rajaobary, Hariniaina David Gaël Tags: Update Source Type: research

Identification of Plasmodium falciparum proteoforms from liver stage models
Immunization with attenuated malaria sporozoites protects humans from experimental malaria challenge by mosquito bite. Protection in humans is strongly correlated with the production of T cells targeting a het... (Source: Malaria Journal)
Source: Malaria Journal - January 7, 2020 Category: Infectious Diseases Authors: Benjamin Winer, Kimberly A. Edgel, Xiaoyan Zou, Julie Sellau, Sri Hadiwidjojo, Lindsey S. Garver, Christin E. McDonough, Neil L. Kelleher, Paul M. Thomas, Eileen Villasante, Alexander Ploss and Vincent R. Gerbasi Tags: Research Source Type: research

Indoor use of attractive toxic sugar bait in combination with long-lasting insecticidal net against pyrethroid-resistant Anopheles gambiae: an experimental hut trial in Mb é, central Côte d’Ivoire
Indoor attractive toxic sugar bait (ATSB) has potential as a supplementary vector-control and resistance-management tool, offering an alternative mode of insecticide delivery to current core vector-control int... (Source: Malaria Journal)
Source: Malaria Journal - January 7, 2020 Category: Infectious Diseases Authors: Joanna E. C. Furnival-Adams, Soromane Camara, Mark Rowland, Alphonsine A. Koffi, Ludovic P. Ahoua Alou, Welbeck A. Oumbouke and Raphael N ’Guessan Tags: Research Source Type: research

Utilization of insecticide-treated bed nets and care-seeking for fever and its associated socio-demographic and geographical factors among under-five children in different regions: evidence from the Myanmar Demographic and Health Survey, 2015 –2016
Malaria is one of the top-five contributors to under-5 deaths in Myanmar. Use of insecticide-treated nets (ITN) and receiving early appropriate care in case of fever are the core interventions to prevent malar... (Source: Malaria Journal)
Source: Malaria Journal - January 6, 2020 Category: Infectious Diseases Authors: Kyi Thar Min, Thae Maung Maung, Myo Minn Oo, Tin Oo, Zaw Lin, Aung Thi and Jaya Prasad Tripathy Tags: Research Source Type: research

The impact of transfluthrin on the spatial repellency of the primary malaria mosquito vectors in Vietnam: Anopheles dirus and Anopheles minimus
The complexity of mosquito-borne diseases poses a major challenge to global health efforts to mitigate their impact on people residing in sub-tropical and tropical regions, to travellers and deployed military ... (Source: Malaria Journal)
Source: Malaria Journal - January 6, 2020 Category: Infectious Diseases Authors: Nicholas J. Martin, Vu S. Nam, Andrew A. Lover, Tran V. Phong, Tran C. Tu and Ian H. Mendenhall Tags: Research Source Type: research

Childhood malaria case incidence in Malawi between 2004 and 2017: spatio-temporal modelling of climate and non-climate factors
Malaria transmission is influenced by a complex interplay of factors including climate, socio-economic, environmental factors and interventions. Malaria control efforts across Africa have shown a mixed impact.... (Source: Malaria Journal)
Source: Malaria Journal - January 6, 2020 Category: Infectious Diseases Authors: James Chirombo, Pietro Ceccato, Rachel Lowe, Dianne J Terlouw, Madeleine C Thomson, Austin Gumbo, Peter J Diggle and Jonathan M Read Tags: Research Source Type: research

Upsurge of malaria transmission after indoor residual spraying withdrawal in Atacora region in Benin, West Africa
In Benin, malaria vector control mostly relies on long-lasting, insecticidal-treated bed nets (LLINs) and indoor residual spraying (IRS) operations. From 2011 to 2016, an IRS programme has been implemented in ... (Source: Malaria Journal)
Source: Malaria Journal - January 3, 2020 Category: Infectious Diseases Authors: Rock Yves A ïkpon, Gil Padonou, Fortuné Dagnon, Razaki Ossè, Aurore Ogouyemi Hounto, Filémon Tokponon, Gorgias Aïkpon, Laurent Lyikirenga and Martin Akogbéto Tags: Research Source Type: research

The use of ultrasensitive quantitative-PCR to assess the impact of primaquine on asymptomatic relapse of Plasmodium vivax infections: a randomized, controlled trial in Lao PDR
Trials to assess the efficacy of the radical cure of Plasmodium vivax malaria with 8-aminoquinolines require that most post-treatment relapses are identified, but there is no consensus on the optimal duration of ... (Source: Malaria Journal)
Source: Malaria Journal - January 3, 2020 Category: Infectious Diseases Authors: Koukeo Phommasone, Frank van Leth, Mallika Imwong, Gisela Henriques, Tiengkham Pongvongsa, Bipin Adhikari, Thomas J. Peto, Cholrawee Promnarate, Mehul Dorda, Pasathorn Sirithiranont, Mavuto Mukaka, Pimnara Peerawaranun, Nicholas P. J. Day, Frank Cobelens, Tags: Research Source Type: research

An in vitro toolbox to accelerate anti-malarial drug discovery and development
Modelling and simulation are being increasingly utilized to support the discovery and development of new anti-malarial drugs. These approaches require reliable in vitro data for physicochemical properties, per... (Source: Malaria Journal)
Source: Malaria Journal - January 2, 2020 Category: Infectious Diseases Authors: Susan A. Charman, Alice Andreu, Helena Barker, Scott Blundell, Anna Campbell, Michael Campbell, Gong Chen, Francis C. K. Chiu, Elly Crighton, Kasiram Katneni, Julia Morizzi, Rahul Patil, Thao Pham, Eileen Ryan, Jessica Saunders, David M. Shackleford & hel Tags: Research Source Type: research

Adherence to malaria rapid diagnostic test result among healthcare workers in Sokoto metropolis, Nigeria
Presumptive diagnosis and prescription of anti-malarial medicines to malaria rapid diagnostic test (RDT)-negative patients is a common practice among health care workers (HCWs) in Nigeria. There is paucity of ... (Source: Malaria Journal)
Source: Malaria Journal - January 2, 2020 Category: Infectious Diseases Authors: Aliyu Mamman Na ’uzo, Dahiru Tukur, Mu’awiyyah Babale Sufiyan, Adebowale Ayo Stephen, IkeOluwapo Ajayi, Eniola Bamgboye, Abdulrazaq Abdullahi Gobir, Chukwuma David Umeokonkwo, Zainab Abdullahi and Olufemi Ajumobi Tags: Research Source Type: research

Antiplasmodial profile of selected compounds from Malaria Box: in vitro evaluation, speed of action and drug combination studies
Artemisinin-based combination therapy (ACT) is used as the first-line treatment of uncomplicated malaria caused by the Plasmodium falciparum parasite and chloroquine-resistant Plasmodium vivax parasites. Evidence... (Source: Malaria Journal)
Source: Malaria Journal - December 30, 2019 Category: Infectious Diseases Authors: Guilherme Eduardo de Souza, Renata Vieira Bueno, Juliana Oliveira de Souza, Camila Lima Zanini, F ábio Cardoso Cruz, Glaucius Oliva, Rafael Victório Carvalho Guido and Anna Caroline Campos Aguiar Tags: Research Source Type: research

Intravenous artesunate plus oral dihydroartemisinin –piperaquine or intravenous quinine plus oral quinine for optimum treatment of severe malaria: lesson learnt from a field hospital in Timika, Papua, Indonesia
Intravenous artesunate and its follow on full course dihydroartemisinin –piperaquine are the standard treatment for severe malaria in Indonesia. The current policy suggests that intravenous and oral quinine cou... (Source: Malaria Journal)
Source: Malaria Journal - December 30, 2019 Category: Infectious Diseases Authors: Silvester Alexandro Sikora, Jeanne Rini Poespoprodjo, Enny Kenangalem, Daniel A. Lampah, Paulus Sugiarto, Ida Safitri Laksono, Riris Andono Ahmad and E. Elsa Herdiana Murhandarwati Tags: Research Source Type: research

The probability of a sequential Plasmodium vivax infection following asymptomatic Plasmodium falciparum and P. vivax infections in Myanmar, Vietnam, Cambodia, and Laos
Adding 8-aminoquinoline to the treatment of falciparum, in addition to vivax malaria, in locations where infections with both species are prevalent could prevent vivax reactivation. The potential risk of haemo... (Source: Malaria Journal)
Source: Malaria Journal - December 30, 2019 Category: Infectious Diseases Authors: Lorenz von Seidlein, Pimnara Peerawaranun, Mavuto Mukaka, Francois H. Nosten, Thuy-Nhien Nguyen, Tran Tinh Hien, Rupam Tripura, Thomas J. Peto, Tiengkham Pongvongsa, Koukeo Phommasone, Mayfong Mayxay, Mallika Imwong, James Watson, Sasithon Pukrittayakamee Tags: Research Source Type: research

Genetic polymorphism of histidine rich protein 2 in Plasmodium falciparum isolates from different infection sources in Yunnan Province, China
Failed diagnoses of some falciparum malaria cases by RDTs are constantly reported in recent years. Plasmodium falciparum histidine-rich protein 2 (pfhpr2) gene deficiency has been found to be the major reason of ... (Source: Malaria Journal)
Source: Malaria Journal - December 30, 2019 Category: Infectious Diseases Authors: Ying Dong, Shuping Liu, Yan Deng, Yanchun Xu, Mengni Chen, Yan Liu and Jingpo Xue Tags: Research Source Type: research

Impact of vector control interventions on malaria transmission intensity, outdoor vector biting rates and Anopheles mosquito species composition in Tororo, Uganda
Long-lasting insecticidal nets (LLINs) and indoor residual spraying of insecticide (IRS) are widely recommended for the prevention of malaria in endemic regions. Data from human landing catches provide informa... (Source: Malaria Journal)
Source: Malaria Journal - December 27, 2019 Category: Infectious Diseases Authors: Alex K. Musiime, David L. Smith, Maxwell Kilama, John Rek, Emmanuel Arinaitwe, Joaniter I. Nankabirwa, Moses R. Kamya, Melissa D. Conrad, Grant Dorsey, Anne M. Akol, Sarah G. Staedke, Steve W. Lindsay and James P. Egonyu Tags: Research Source Type: research

Clinical diagnostic evaluation of HRP2 and pLDH-based rapid diagnostic tests for malaria in an area receiving seasonal malaria chemoprevention in Niger
Rapid diagnostic tests (RDT) for malaria are common, but their performance varies. Tests using histidine-rich protein 2 (HRP2) antigen are most common, and many have high sensitivity. HRP2 tests can remain pos... (Source: Malaria Journal)
Source: Malaria Journal - December 26, 2019 Category: Infectious Diseases Authors: Matthew E. Coldiron, Bachir Assao, C éline Langendorf, Nathan Sayinzoga-Makombe, Iza Ciglenecki, Roberto de la Tour, Erwan Piriou, Mahaman Yarima Bako, Ann Mumina, Ousmane Guindo, Anne-Laure Page and Rebecca F. Grais Tags: Research Source Type: research

Indigenously developed digital handheld Android-based Geographic Information System (GIS)-tagged tablets (TABs) in malaria elimination programme in Mangaluru city, Karnataka, India
Under-reporting, delayed diagnosis, incomplete treatment and inadequate vector management are few among many factors responsible for uninterrupted transmission of malaria in India. Information technology (IT) ... (Source: Malaria Journal)
Source: Malaria Journal - December 26, 2019 Category: Infectious Diseases Authors: B. Shantharam Baliga, Animesh Jain, Naren Koduvattat, B. G. Prakash Kumar, Manu Kumar, Arun Kumar and Susanta K. Ghosh Tags: Methodology Source Type: research

Economic considerations support C-reactive protein testing alongside malaria rapid diagnostic tests to guide antimicrobial therapy for patients with febrile illness in settings with low malaria endemicity
Malaria is no longer a common cause of febrile illness in many regions of the tropics. In part, this success is a result of improved access to accurate diagnosis and effective anti-malarial treatment, includin... (Source: Malaria Journal)
Source: Malaria Journal - December 26, 2019 Category: Infectious Diseases Authors: Yoel Lubell, Arjun Chandna, Frank Smithuis, Lisa White, Heiman F. L. Wertheim, Ma ël Redard-Jacot, Zachary Katz, Arjen Dondorp, Nicholas Day, Nicholas White and Sabine Dittrich Tags: Opinion Source Type: research

Characterising malaria connectivity using malaria indicator survey data
Malaria connectivity describes the flow of parasites among transmission sources and sinks within a given landscape. Because of the spatial and temporal scales at which parasites are transported by their hosts,... (Source: Malaria Journal)
Source: Malaria Journal - December 23, 2019 Category: Infectious Diseases Authors: Carlos A. Guerra, Daniel T. Citron, Guillermo A. Garc ía and David L. Smith Tags: Commentary Source Type: research

The development and evaluation of a self-marking unit to estimate malaria vector survival and dispersal distance
A clear understanding of mosquito biology is fundamental to the control efforts of mosquito-borne diseases such as malaria. Mosquito mark-release-recapture (MMRR) experiments are a popular method of measuring ... (Source: Malaria Journal)
Source: Malaria Journal - December 23, 2019 Category: Infectious Diseases Authors: Adam Saddler, Katharina S. Kreppel, Nakul Chitnis, Thomas A. Smith, Adrian Denz, Jason D. Moore, Mgeni M. Tambwe and Sarah J. Moore Tags: Research Source Type: research

Effectiveness of plant-based repellents against different Anopheles species: a systematic review
Plant-based repellents have been applied for generations in traditional practice as a personal protection approach against different species of Anopheles. Knowledge of traditional repellent plants is a significan... (Source: Malaria Journal)
Source: Malaria Journal - December 21, 2019 Category: Infectious Diseases Authors: Amin Asadollahi, Mehdi Khoobdel, Alireza Zahraei-Ramazani, Sahar Azarmi and Sayed Hussain Mosawi Tags: Review Source Type: research

Understanding challenges to malaria elimination in Nepal: a qualitative study with an embedded capacity-building exercise
The Nepalese Government has made significant progress toward the elimination of malaria. However, given the surge in the prevalence of non-communicable diseases, such as diabetes and hypertension, and the loca... (Source: Malaria Journal)
Source: Malaria Journal - December 21, 2019 Category: Infectious Diseases Authors: Shiva Raj Adhikari, Vishnu P. Sapkota, Arjun K. Thapa and Yubraj Acharya Tags: Research Source Type: research

Adherence to the referral advice after introduction of rectal artesunate for pre-referral treatment of severe malaria at the community level: a noninferiority trial in the Democratic Republic of the Congo
The Democratic Republic of the Congo adopted the strategy of using, at the community level, a dose of rectal artesunate as a pre-referral treatment for severe malaria amongst children under 5 years who could n... (Source: Malaria Journal)
Source: Malaria Journal - December 21, 2019 Category: Infectious Diseases Authors: Patrick M. Mvumbi, Jeanine Musau, Ousmane Faye, Hyppolite Situakibanza and Emile Okitolonda Tags: Research Source Type: research

Doses of chloroquine in the treatment of malaria by Plasmodium vivax in patients between 2 and 14 years of age from the Brazilian Amazon basin
A total dose of chloroquine of 25 mg/kg is recommended by the World Health Organization (WHO) to treat malaria by Plasmodium vivax. In several endemic areas, including the Brazilian Amazon basin, anti-malarial dr... (Source: Malaria Journal)
Source: Malaria Journal - December 21, 2019 Category: Infectious Diseases Authors: Luann Wendel Pereira de Sena, Amanda Gabryelle Nunes Cardoso Mello, Michelle Val éria Dias Ferreira, Marcieni Andrade de Ataide, Rosa Maria Dias and José Luiz Fernandes Vieira Tags: Research Source Type: research

Risk factor assessment for clinical malaria among forest-goers in a pre-elimination setting in Phu Yen Province, Vietnam
The transition from malaria control to elimination requires understanding and targeting interventions among high-risk populations. In Vietnam, forest-goers are often difficult to test, treat and follow-up for ... (Source: Malaria Journal)
Source: Malaria Journal - December 20, 2019 Category: Infectious Diseases Authors: Sara E. Canavati, Gerard C. Kelly, Cesia E. Quintero, Thuan Huu Vo, Long Khanh Tran, Colin Ohrt, Thang Duc Ngo, Duong Thanh Tran and Nicholas J. Martin Tags: Research Source Type: research

High cases of submicroscopic Plasmodium falciparum infections in a suburban population of Lagos, Nigeria
Asymptomatic malaria parasites are significant sources of infections for onward malaria transmission. Conventional tools for malaria diagnosis such as microscopy and rapid diagnostic test kits (RDT) have relat... (Source: Malaria Journal)
Source: Malaria Journal - December 19, 2019 Category: Infectious Diseases Authors: Florence A. Umunnakwe, Emmanuel T. Idowu, Olusola Ajibaye, Blessed Etoketim, Samuel Akindele, Aminat O. Shokunbi, Olubunmi A. Otubanjo, Gordon A. Awandare, Alfred Amambua-Ngwa and Kolapo M. Oyebola Tags: Research Source Type: research

IL35 modulation altered survival, cytokine environment and histopathological consequences during malaria infection in mice
The immune modulating potential of IL-35 in multiple human disorders has been reported. Consequent upon the recognition of inflammatory cytokine activation and its preponderance for mediating pathology during ... (Source: Malaria Journal)
Source: Malaria Journal - December 19, 2019 Category: Infectious Diseases Authors: Ramatu Omenesa Bello, Maizaton Atmadini Abdullah, Roslaini Abd Majid, Voon Kin Chin, Mohammed Faruq Abd Rachman Isnadi, Zaid Osama Ibraheem, Mohd Khairi Hussain, Mohammed Garba Magaji and Rusliza Basir Tags: Research Source Type: research

The 2019 Isdell:Flowers Cross Border Malaria Initiative Round Table: community engagement in the context of malaria elimination
Government officials, representatives from malaria endemic communities, and nonprofit, academic, and private sector partners convened at the 2019 Isdell:Flowers Cross Border Malaria Initiative Round Table in L... (Source: Malaria Journal)
Source: Malaria Journal - December 19, 2019 Category: Infectious Diseases Authors: Alexandra Gordon, Rebecca J. Vander Meulen and Alysse Maglior Tags: Meeting report Source Type: research

Markers of sulfadoxine –pyrimethamine resistance in Eastern Democratic Republic of Congo; implications for malaria chemoprevention
Sulfadoxine –pyrimethamine (SP) is a cornerstone of malaria chemoprophylaxis and is considered for programmes in the Democratic Republic of Congo (DRC). However, SP efficacy is threatened by drug resistance, th... (Source: Malaria Journal)
Source: Malaria Journal - December 18, 2019 Category: Infectious Diseases Authors: Marit van Lenthe, Renske van der Meulen, Maryvonne Lassovski, Adelaide Ouabo, Edwige Bakula, Colette Badio, Deogratias Cibenda, Lucy Okell, Erwan Piriou, Lynn Grignard, Kjerstin Lanke, Bhargavi Rao, Teun Bousema and Cally Roper Tags: Research Source Type: research

Optimization of an in vivo model to study immunity to Plasmodium falciparum pre-erythrocytic stages
The circumsporozoite protein (CSP) of Plasmodium is a key surface antigen that induces antibodies and T-cells, conferring immune protection in animal models and humans. However, much of the work on CSP and immuni... (Source: Malaria Journal)
Source: Malaria Journal - December 18, 2019 Category: Infectious Diseases Authors: Yevel Flores-Garcia, Sonia M. Herrera, Hugo Jhun, Daniel W. P érez-Ramos, C. Richter King, Emily Locke, Ramadevi Raghunandan and Fidel Zavala Tags: Research Source Type: research

Anti-malarial ozonides OZ439 and OZ609 tested at clinically relevant compound exposure parameters in a novel ring-stage survival assay
Drug efficacy against kelch 13 mutant malaria parasites can be determined in vitro with the ring-stage survival assay (RSA). The conventional assay protocol reflects the exposure profile of dihydroartemisinin. (Source: Malaria Journal)
Source: Malaria Journal - December 18, 2019 Category: Infectious Diseases Authors: Annabelle Walz, Didier Leroy, Nicole Andenmatten, Pascal M äser and Sergio Wittlin Tags: Research Source Type: research

Intracluster correlation coefficients in the Greater Mekong Subregion for sample size calculations of cluster randomized malaria trials
Sample size calculations for cluster randomized trials are a recognized methodological challenge for malaria research in pre-elimination settings. Positively correlated responses from the participants in the s... (Source: Malaria Journal)
Source: Malaria Journal - December 18, 2019 Category: Infectious Diseases Authors: Pimnara Peerawaranun, Jordi Landier, Francois H. Nosten, Thuy-Nhien Nguyen, Tran Tinh Hien, Rupam Tripura, Thomas J. Peto, Koukeo Phommasone, Mayfong Mayxay, Nicholas P. J. Day, Arjen Dondorp, Nick White, Lorenz von Seidlein and Mavuto Mukaka Tags: Methodology Source Type: research

Management of imported malaria cases and healthcare institutions in central China, 2012 –2017: application of decision tree analysis
Imported malaria has been an important challenge for China. Fatality rates from malaria increased in China, particularly in Henan Province, primarily due to malpractice and misdiagnoses in healthcare instituti... (Source: Malaria Journal)
Source: Malaria Journal - December 18, 2019 Category: Infectious Diseases Authors: Xi-Liang Wang, Jie-Bin Cao, Dan-Dan Li, Dong-Xiao Guo, Cheng-Da Zhang, Xiao Wang, Dan-Kang Li, Qing-Lin Zhao, Xiao-Wen Huang and Wei-Dong Zhang Tags: Research Source Type: research