Effect of pharmacogenetics on plasma lumefantrine pharmacokinetics and malaria treatment outcome in pregnant women
Pregnancy has considerable effects on the pharmacokinetic properties of drugs used to treat uncomplicated Plasmodium falciparum malaria. The role of pharmacogenetic variation on anti-malarial drug disposition and... (Source: Malaria Journal)
Source: Malaria Journal - July 3, 2017 Category: Infectious Diseases Authors: Ritah F. Mutagonda, Appolinary A. R. Kamuhabwa, Omary M. S. Minzi, Siriel N. Massawe, Muhammad Asghar, Manijeh V. Homann, Anna F ärnert and Eleni Aklillu Source Type: research

Anti-malarial treatment outcomes in Ethiopia: a systematic review and meta-analysis
Ethiopia is among countries with a high malaria burden. There are several studies that assessed the efficacy of anti-malarial agents in the country and this systematic review and meta-analysis was performed to... (Source: Malaria Journal)
Source: Malaria Journal - July 3, 2017 Category: Infectious Diseases Authors: Eyob Alemayehu Gebreyohannes, Akshaya Srikanth Bhagavathula, Mohammed Assen Seid and Henok Getachew Tegegn Source Type: research

Genetic diversity and natural selection of Plasmodium vivax multi-drug resistant gene (pvmdr1) in Mesoamerica
The Plasmodium vivax multidrug resistant 1 gene (pvmdr1) codes for a transmembrane protein of the parasite ’s digestive vacuole. It is likely that the pvmdr1 gene mutations occur at different sites by convergent e... (Source: Malaria Journal)
Source: Malaria Journal - July 1, 2017 Category: Infectious Diseases Authors: Lilia Gonz ález-Cerón, Alberto Montoya, Josselin C. Corzo-Gómez, Rene Cerritos, Frida Santillán and Marco A. Sandoval Source Type: research

Factors influencing the ownership and utilization of long-lasting insecticidal nets for malaria prevention in Ethiopia
Utilization of long-lasting insecticidal nets (LLINs) is regarded as key malaria prevention and control strategy. However, studies have reported a large gap in terms of both ownership and utilization particula... (Source: Malaria Journal)
Source: Malaria Journal - July 1, 2017 Category: Infectious Diseases Authors: Admasu Tassew, Richard Hopkins and Wakgari Deressa Source Type: research

Yeast lysates carrying the nucleoprotein from measles virus vaccine as a novel subunit vaccine platform to deliver Plasmodium circumsporozoite antigen
Yeast cells represent an established bioreactor to produce recombinant proteins for subunit vaccine development. In addition, delivery of vaccine antigens directly within heat-inactivated yeast cells is attrac... (Source: Malaria Journal)
Source: Malaria Journal - June 29, 2017 Category: Infectious Diseases Authors: Daria Jacob, Claude Ruffie, Chantal Combredet, Pauline Formaglio, Rogerio Amino, Robert M énard, Frédéric Tangy and Monica Sala Source Type: research

Non-imported malaria in non-endemic countries: a review of cases in Spain
Spain declared the elimination of malaria in 1964. In non-endemic areas, the overwhelming majority of malaria cases are acquired abroad, and locally acquired infections are rare events. In Spain, malaria is a ... (Source: Malaria Journal)
Source: Malaria Journal - June 29, 2017 Category: Infectious Diseases Authors: Emilia Velasco, Diana Gomez-Barroso, Carmen Varela, Oliva Diaz and Rosa Cano Source Type: research

Imported Plasmodium falciparum and locally transmitted Plasmodium vivax: cross-border malaria transmission scenario in northwestern Thailand
Cross-border malaria transmission is an important problem for national malaria control programmes. The epidemiology of cross-border malaria is further complicated in areas where Plasmodium falciparum and Plasmodi... (Source: Malaria Journal)
Source: Malaria Journal - June 21, 2017 Category: Infectious Diseases Authors: Patchara Sriwichai, Stephan Karl, Yudthana Samung, Kirakorn Kiattibutr, Jeeraphat Sirichaisinthop, Ivo Mueller, Liwang Cui and Jetsumon Sattabongkot Source Type: research

Perennial transmission of malaria in the low altitude areas of Baringo County, Kenya
Malaria causes the greatest public health burden in sub-Saharan Africa where high mortality occurs mainly in children under 5 years of age. Traditionally, malaria has been reported mainly in the lowlands endem... (Source: Malaria Journal)
Source: Malaria Journal - June 17, 2017 Category: Infectious Diseases Authors: Collince J. Omondi, Daniel Onguru, Lucy Kamau, Mark Nanyingi, George Ong ’amo and Benson Estambale Source Type: research

G6PD deficiency alleles in a malaria-endemic region in the Western Brazilian Amazon
Plasmodium vivax parasites are the predominant cause of malaria infections in the Brazilian Amazon. Infected individuals are treated with primaquine, which can induce haemolytic anaemi... (Source: Malaria Journal)
Source: Malaria Journal - June 15, 2017 Category: Infectious Diseases Authors: Jamille G. Dombrowski, Rodrigo M. Souza, Jonathan Curry, Laura Hinton, Natercia R. M. Silva, Lynn Grignard, Ligia A. Gon çalves, Ana Rita Gomes, Sabrina Epiphanio, Chris Drakeley, Jim Huggett, Taane G. Clark, Susana Campino and Claudio R. F. Marinho Source Type: research

Effectiveness and equity of the Tanzania National Voucher Scheme for mosquito nets over 10  years of implementation
The Tanzania National Voucher Scheme (TNVS) was a public private partnership managed by the Ministry of Health that provided pregnant women and infants with highly subsidized (long-lasting) insecticide-treated... (Source: Malaria Journal)
Source: Malaria Journal - June 15, 2017 Category: Infectious Diseases Authors: Karen Kramer, Renata Mandike, Rose Nathan, Ally Mohamed, Matthew Lynch, Nick Brown, Ally Mnzava, Wilhelmina Rimisho and Christian Lengeler Source Type: research

Social representations of malaria in the Guna indigenous population of Comarca Guna de Madungandi, Panama
The purpose of the study was to recognize the social representation of the Guna indigenous population by identifying cultural elements related to malaria, in order to create an intercultural approach to any he... (Source: Malaria Journal)
Source: Malaria Journal - June 15, 2017 Category: Infectious Diseases Authors: Lorenzo C áceres, José E. Calzada, Amanda Gabster, Josue Young, Ricardo Márquez, Rolando Torres and Margarita Griffith Source Type: research

New adenovirus-based vaccine vectors targeting Pfs25 elicit antibodies that inhibit Plasmodium falciparum transmission
An effective malaria transmission-blocking vaccine (TBV) would be a major advance in the current efforts to eliminate and, ultimately, eradicate malaria. Antibodies against Plasmodium falciparum surface protein, ... (Source: Malaria Journal)
Source: Malaria Journal - June 15, 2017 Category: Infectious Diseases Authors: Kathleen A. McGuire, Kazutoyo Miura, Christopher M. Wiethoff and Kim C. Williamson Source Type: research

Engaging the private sector in malaria surveillance: a review of strategies and recommendations for elimination settings
In malaria elimination settings, all malaria cases must be identified, documented and investigated. To facilitate complete and timely reporting of all malaria cases and effective case management and follow-up,... (Source: Malaria Journal)
Source: Malaria Journal - June 14, 2017 Category: Infectious Diseases Authors: Adam Bennett, Anton L. V. Avance ña, Jennifer Wegbreit, Chris Cotter, Kathryn Roberts and Roly Gosling Source Type: research

Ex vivo susceptibility and genotyping of Plasmodium falciparum isolates from Pikine, Senegal
The monitoring of Plasmodium falciparum sensitivity to anti-malarial drugs is a necessity for effective case management of malaria. This species is characterized by a strong resistance to anti-malarial drugs. In ... (Source: Malaria Journal)
Source: Malaria Journal - June 14, 2017 Category: Infectious Diseases Authors: Aminata Mbaye, Amy Gaye, Baba Dieye, Yaye D. Ndiaye, Amy K. Bei, Muna Affara, Awa B. Deme, Mamadou S. Yade, Khadim Diongue, Ibrahima M. Ndiaye, Tolla Ndiaye, Mouhamed Sy, Ngayo Sy, Ousmane Koita, Donald J. Krogstad, Sarah Volkman & hellip; Source Type: research

Reported community-level indoor residual spray coverage from two-stage cluster surveys in sub-Saharan Africa
Malaria is an important cause of morbidity and mortality in malaria-endemic areas. Indoor residual spray is an effective intervention to control malaria, but high community-level coverage is needed to maximize... (Source: Malaria Journal)
Source: Malaria Journal - June 13, 2017 Category: Infectious Diseases Authors: David A. Larsen, Lauren Borrill, Ryan Patel and Lauren Fregosi Source Type: research

Suppression of experimental cerebral malaria by disruption of malate:quinone oxidoreductase
Aspartate, which is converted from oxaloacetate (OAA) by aspartate aminotransferase, is considered an important precursor for purine salvage and pyrimidine de novo biosynthesis, and is thus indispensable for t... (Source: Malaria Journal)
Source: Malaria Journal - June 12, 2017 Category: Infectious Diseases Authors: Mamoru Niikura, Keisuke Komatsuya, Shin-Ichi Inoue, Risa Matsuda, Hiroko Asahi, Daniel Ken Inaoka, Kiyoshi Kita and Fumie Kobayashi Source Type: research

Malaria research in Malawi from 1984 to 2016: a literature review and bibliometric analysis
Malaria research can play a vital role in addressing the malaria burden in Malawi. An organized approach in addressing malaria in Malawi started in 1984 by the establishment of the first National Malaria Contr... (Source: Malaria Journal)
Source: Malaria Journal - June 12, 2017 Category: Infectious Diseases Authors: Chikondi A. Mwendera, Christiaan de Jager, Herbert Longwe, Charles Hongoro, Clifford M. Mutero and Kamija S. Phiri Source Type: research

Effectiveness of reactive case detection for malaria elimination in three archetypical transmission settings: a modelling study
Reactive case detection could be a powerful tool in malaria elimination, as it selectively targets transmission pockets. However, field operations have yet to demonstrate under which conditions, if any, reacti... (Source: Malaria Journal)
Source: Malaria Journal - June 12, 2017 Category: Infectious Diseases Authors: Jaline Gerardin, Caitlin A. Bever, Daniel Bridenbecker, Busiku Hamainza, Kafula Silumbe, John M. Miller, Thomas P. Eisele, Philip A. Eckhoff and Edward A. Wenger Source Type: research

The role of extracellular vesicles in malaria biology and pathogenesis
In the past decade, research on the functions of extracellular vesicles in malaria has expanded dramatically. Investigations into the various vesicle types, from both host and parasite origin, has revealed imp... (Source: Malaria Journal)
Source: Malaria Journal - June 9, 2017 Category: Infectious Diseases Authors: Natalia Guimaraes Sampaio, Lesley Cheng and Emily M. Eriksson Source Type: research

Access to and use of long-lasting insecticidal nets and factors associated with non-use among communities in malaria-endemic areas of Al Hudaydah governorate in the Tihama region, west of Yemen
Universal coverage of the targeted malaria-endemic areas with long-lasting insecticidal nets (LLINs) is implemented as one of the key interventions for malaria control and elimination in Yemen. In 2013, throug... (Source: Malaria Journal)
Source: Malaria Journal - June 9, 2017 Category: Infectious Diseases Authors: Samira M. A. Al-Eryani, Mohammed A. K. Mahdy, Abdulsalam M. Al-Mekhlafi and Rashad Abdul-Ghani Source Type: research

Current and cumulative malaria infections in a setting embarking on elimination: Amhara, Ethiopia
Since 2005, Ethiopia has aggressively scaled up malaria prevention and case management. As a result, the number of malaria cases and deaths has significantly declined. In order to track progress towards the el... (Source: Malaria Journal)
Source: Malaria Journal - June 8, 2017 Category: Infectious Diseases Authors: Woyneshet G. Yalew, Sampa Pal, Pooja Bansil, Rebecca Dabbs, Kevin Tetteh, Caterina Guinovart, Michael Kalnoky, Belendia A. Serda, Berhane H. Tesfay, Belay B. Beyene, Catherine Seneviratne, Megan Littrell, Lindsay Yokobe, Gregory S. Noland, Gonzalo J. Domi Source Type: research

Extremely low Plasmodium prevalence in wild plovers and coursers from Cape Verde and Madagascar
Relatively little is known about the prevalence of blood parasites in shorebirds, especially those breeding in the tropics. The prevalence of blood parasites of the genera Plasmodium, Haemoproteus and Leucocytozo... (Source: Malaria Journal)
Source: Malaria Journal - June 8, 2017 Category: Infectious Diseases Authors: Josu é Martínez-de la Puente, Luke J. Eberhart-Phillips, M. Cristina Carmona-Isunza, Sama Zefania, María José Navarro, Oliver Kruger, Joseph Ivan Hoffman, Tamás Székely and Jordi Figuerola Source Type: research

Plasmobase: a comparative database of predicted domain architectures for Plasmodium genomes
With the availability of complete genome sequences of both human and non-human Plasmodium parasites, it is now possible to use comparative genomics to look for orthology across Plasmodium species and for species ... (Source: Malaria Journal)
Source: Malaria Journal - June 7, 2017 Category: Infectious Diseases Authors: Juliana Bernardes, Catherine Vaquero and Alessandra Carbone Source Type: research

Community-based intermittent mass testing and treatment for malaria in an area of high transmission intensity, western Kenya: study design and methodology for a cluster randomized controlled trial
Most human Plasmodium infections in western Kenya are asymptomatic and are believed to contribute importantly to malaria transmission. Elimination of asymptomatic infections requires active treatment approaches, ... (Source: Malaria Journal)
Source: Malaria Journal - June 7, 2017 Category: Infectious Diseases Authors: Aaron M. Samuels, Nobert Awino, Wycliffe Odongo, Benard Abong ’o, John Gimnig, Kephas Otieno, Ya Ping Shi, Vincent Were, Denise Roth Allen, Florence Were, Tony Sang, David Obor, John Williamson, Mary J. Hamel, S. Patrick Kachur, Laurence Slutsker & hell Source Type: research

Ivermectin-treated cattle reduces blood digestion, egg production and survival of a free-living population of Anopheles arabiensis under semi-field condition in south-eastern Tanzania
Anopheles arabiensis feed on cattle and contributes to residual transmission of malaria in areas with high coverage of long-lasting insecticide-treated nets and indoor residual sprayin... (Source: Malaria Journal)
Source: Malaria Journal - June 6, 2017 Category: Infectious Diseases Authors: Issa N. Lyimo, Stella T. Kessy, Kasian F. Mbina, Ally A. Daraja and Ladslaus L. Mnyone Source Type: research

Genome-wide scans for the identification of Plasmodium vivax genes under positive selection
The current trend of Plasmodium vivax cases imported from Southeast Asia into China has sharply increased recently, especially from the China –Myanmar border (CMB) area. High recombination rates of P. vivax popula... (Source: Malaria Journal)
Source: Malaria Journal - June 6, 2017 Category: Infectious Diseases Authors: Hai-Mo Shen, Shen-Bo Chen, Yue Wang, Bin Xu, Eniola Michael Abe and Jun-Hu Chen Source Type: research

Comparative physical genome mapping of malaria vectors Anopheles sinensis and Anopheles gambiae
Anopheles sinensis is a dominant natural vector of Plasmodium vivax in China, Taiwan, Japan, and Korea. Recent genome sequencing of An. sinensis provides important insights into the ge... (Source: Malaria Journal)
Source: Malaria Journal - June 5, 2017 Category: Infectious Diseases Authors: Yun Wei, Biao Cheng, Guoding Zhu, Danyu Shen, Jiangtao Liang, Cong Wang, Jing Wang, Jianxia Tang, Jun Cao, Igor V. Sharakhov and Ai Xia Source Type: research

Surveillance for sulfadoxine-pyrimethamine resistant malaria parasites in the Lake and Southern Zones, Tanzania, using pooling and next-generation sequencing
Malaria in pregnancy (MiP) remains a major public health challenge in areas of high malaria transmission. Intermittent preventive treatment in pregnancy (IPTp) with sulfadoxine-pyrimethamine (SP) is recommende... (Source: Malaria Journal)
Source: Malaria Journal - June 5, 2017 Category: Infectious Diseases Authors: Jeremiah M. Ngondi, Deus S. Ishengoma, Stephanie M. Doctor, Kyaw L. Thwai, Corinna Keeler, Sigsbert Mkude, Oresto M. Munishi, Ritha A. Willilo, Shabbir Lalji, Naomi Kaspar, Chonge Kitojo, Lynn A. Paxton, Nicholas J. Hathaway, Jeffrey A. Bailey, Jonathan J Source Type: research

Molecular characterization of Anopheline (Diptera: Culicidae) mosquitoes from eight geographical locations of Sri Lanka
Genus Anopheles is a major mosquito group of interest in Sri Lanka as it includes vectors of malaria and its members exist as species complexes. Taxonomy of the group is mainly based on morphological features, wh... (Source: Malaria Journal)
Source: Malaria Journal - June 2, 2017 Category: Infectious Diseases Authors: Thilini C. Weeraratne, Sinnathambi N. Surendran, Lisa J. Reimer, Charles S. Wondji, M. Devika B. Perera, Catherine Walton and S. H. P. Parakrama Karunaratne Source Type: research

Effect of user preferences on ITN use: a review of literature and data
Insecticide-treated bed nets (ITNs) are the primary tool for vector control, and optimizing ITN use is a key concern of national programmes. Available evidence indicates that bed net users often have preferenc... (Source: Malaria Journal)
Source: Malaria Journal - June 1, 2017 Category: Infectious Diseases Authors: Hannah Koenker and Joshua O. Yukich Source Type: research

Assessment of climate-driven variations in malaria incidence in Swaziland: toward malaria elimination
Swaziland aims to eliminate malaria by 2020. However, imported cases from neighbouring endemic countries continue to sustain local parasite reservoirs and initiate transmission. As certain weather and climatic... (Source: Malaria Journal)
Source: Malaria Journal - June 1, 2017 Category: Infectious Diseases Authors: Ting-Wu Chuang, Adam Soble, Nyasatu Ntshalintshali, Nomcebo Mkhonta, Eric Seyama, Steven Mthethwa, Deepa Pindolia and Simon Kunene Source Type: research

Evaluation of the knowledge and attitude of pharmacists about the national malaria control policy in southern Benin
The national strategy against malaria in an endemic country should involve all the health stakeholders. In Benin, the private sector is rarely present in the activities of the National Malaria Control Programm... (Source: Malaria Journal)
Source: Malaria Journal - May 31, 2017 Category: Infectious Diseases Authors: Habib Ganfon, Giraud Ekanmian, Louis Amoussou, Emilie Daniel-Garcia and Aurel Constant Allabi Source Type: research

Fast and robust single PCR for Plasmodium sporozoite detection in mosquitoes using the cytochrome oxidase I gene
Molecular tools for detecting malaria-infected mosquitoes with improved practicality, sensitivity and specificity, and high-throughput are required. A common PCR technique used to detect mosquitoes infected with (Source: Malaria Journal)
Source: Malaria Journal - May 31, 2017 Category: Infectious Diseases Authors: Diego F. Echeverry, Nicholas A. Deason, Victoria Makuru, Jenna Davidson, Honglin Xiao, Julie Niedbalski, Xiaoyu Yu, Jennifer C. Stevenson, Hugo Bugoro, Allan Aparaimo, Hedrick Reuben, Robert Cooper, Thomas R. Burkot, Tanya L. Russell, Frank H. Collins and Source Type: research

Molecular and immunological analyses of confirmed Plasmodium vivax relapse episodes
Relapse infections resulting from the activation hypnozoites produced by Plasmodium vivax and Plasmodium ovale represent an important obstacle to the successful control of these species. A single licensed drug, p... (Source: Malaria Journal)
Source: Malaria Journal - May 30, 2017 Category: Infectious Diseases Authors: Sarunya Maneerattanasak, Panita Gosi, Srivicha Krudsood, Pattamawan Chimma, Jarinee Tongshoob, Yuvadee Mahakunkijcharoen, Chonlaphat Sukasem, Mallika Imwong, Georges Snounou and Srisin Khusmith Source Type: research

Rapid reduction of malaria following introduction of vector control interventions in Tororo District, Uganda: a descriptive study
In 2012, Tororo District had the highest malaria burden in Uganda with community Plasmodium prevalence of 48%. To control malaria in the district, the Ministry of Health introduced universal distribution of long ... (Source: Malaria Journal)
Source: Malaria Journal - May 30, 2017 Category: Infectious Diseases Authors: David W. Oguttu, Joseph K. B. Matovu, David C. Okumu, Alex R. Ario, Allen E. Okullo, Jimmy Opigo and Victoria Nankabirwa Source Type: research

A metabolomic analytical approach permits identification of urinary biomarkers for Plasmodium falciparum infection: a case –control study
Currently available diagnostic techniques of Plasmodium falciparum infection are not optimal for non-invasive, population-based screening for malaria. It was hypothesized that a mass spectrometry-based metabolomi... (Source: Malaria Journal)
Source: Malaria Journal - May 30, 2017 Category: Infectious Diseases Authors: Salah Abdelrazig, Catharine A. Ortori, Gail Davey, Wakgari Deressa, Dhaba Mulleta, David A. Barrett, Alemayehu Amberbir and Andrew W. Fogarty Source Type: research

Elimination of Plasmodium falciparum malaria in Tajikistan
Malaria was eliminated in Tajikistan by the beginning of the 1960s. However, sporadic introduced cases of malaria occurred subsequently probably as a result of transmission from infected mosquito Anopheles fly... (Source: Malaria Journal)
Source: Malaria Journal - May 30, 2017 Category: Infectious Diseases Authors: Anatoly V. Kondrashin, Azizullo S. Sharipov, Dilshod S. Kadamov, Saifuddin S. Karimov, Elkhan Gasimov, Alla M. Baranova, Lola F. Morozova, Ekaterina V. Stepanova, Natalia A. Turbabina, Maria S. Maksimova and Evgeny N. Morozov Source Type: research

Insecticide-treated nets provide protection against malaria to children in an area of insecticide resistance in Southern Benin
Malaria control is heavily reliant on insecticides, especially pyrethroids. Resistance of mosquitoes to insecticides may threaten the effectiveness of insecticide-based vector control and lead to a resurgence ... (Source: Malaria Journal)
Source: Malaria Journal - May 26, 2017 Category: Infectious Diseases Authors: John Bradley, Aurore Ogouy èmi-Hounto, Sylvie Cornélie, Jacob Fassinou, Yolande Sissinto Savi de Tove, Adicath Adéola Adéothy, Filémon T. Tokponnon, Patrick Makoutode, Alioun Adechoubou, Thibaut Legba, Telesphore Houansou, Dorothée Kinde-Gazard, Mar Source Type: research

Effect of IPTp on Plasmodium falciparum antibody levels among pregnant women and their babies in a sub-urban coastal area in Ghana
Women exposed to Plasmodium infection develop antibodies and become semi-immune. This immunity is suppressed during pregnancy making both the pregnant woman and the foetus vulnerable to the adverse effects of mal... (Source: Malaria Journal)
Source: Malaria Journal - May 26, 2017 Category: Infectious Diseases Authors: Judith K. Stephens, Eric Kyei-Baafour, Emmanuel K. Dickson, Jones K. Ofori, Michael F. Ofori, Mark L. Wilson, Isabella A. Quakyi and Bartholomew D. Akanmori Source Type: research

Evaluation of a laboratory quality assurance pilot programme for malaria diagnostics in low-transmission areas of Kenya, 2013
One objective of the Kenya National Malaria Strategy 2009 –2017 is scaling access to prompt diagnosis and effective treatment. In 2013, a quality assurance (QA) pilot was implemented to improve accuracy of mala... (Source: Malaria Journal)
Source: Malaria Journal - May 25, 2017 Category: Infectious Diseases Authors: Elizabeth Wanja, Rachel Achilla, Peter Obare, Rose Adeny, Caroline Moseti, Victor Otieno, Collins Morang ’a, Ephantus Murigi, John Nyamuni, Derek R. Monthei, Bernhards Ogutu and Ann M. Buff Source Type: research

Malaria prevalence in asymptomatic and symptomatic children in Kiwangwa, Bagamoyo district, Tanzania
Malaria prevalence continues to decline across sub-Saharan Africa as a result of various intervention strategies. However, the diseases still poses a public health concern in the region. While symptomatic mala... (Source: Malaria Journal)
Source: Malaria Journal - May 25, 2017 Category: Infectious Diseases Authors: Deborah Sumari, Felista Mwingira, Majige Selemani, Joseph Mugasa, Kefas Mugittu and Paul Gwakisa Source Type: research

Assessment of coverage of preventive treatment and insecticide-treated mosquito nets in pregnant women attending antenatal care services in 11 districts in Mozambique in 2011: the critical role of supply chain
Malaria during pregnancy is associated with poor maternal and pregnancy outcome and the World Health Organization recommends the administration of intermittent preventive treatment in pregnancy (IPTp) with sul... (Source: Malaria Journal)
Source: Malaria Journal - May 25, 2017 Category: Infectious Diseases Authors: Cristolde Salom ão, Jahit Sacarlal and Eduardo Samo Gudo Source Type: research

Effect of climatic variability on malaria trends in Baringo County, Kenya
Malaria transmission in arid and semi-arid regions of Kenya such as Baringo County, is seasonal and often influenced by climatic factors. Unravelling the relationship between climate variables and malaria tran... (Source: Malaria Journal)
Source: Malaria Journal - May 25, 2017 Category: Infectious Diseases Authors: Edwin K. Kipruto, Alfred O. Ochieng, Douglas N. Anyona, Macrae Mbalanya, Edna N. Mutua, Daniel Onguru, Isaac K. Nyamongo and Benson B. A. Estambale Source Type: research

Private sector role, readiness and performance for malaria case management in Uganda, 2015
Several interventions have been put in place to promote access to quality malaria case management services in Uganda ’s private sector, where most people seek treatment. This paper describes evidence using a mi... (Source: Malaria Journal)
Source: Malaria Journal - May 25, 2017 Category: Infectious Diseases Authors: Henry Kaula, Peter Buyungo and Jimmy Opigo Source Type: research

Do anti-malarials in Africa meet quality standards? The market penetration of non quality-assured artemisinin combination therapy in eight African countries
Quality of artemisinin-based combination therapy (ACT) is important for ensuring malaria parasite clearance and protecting the efficacy of artemisinin-based therapies. The extent to which non quality-assured A... (Source: Malaria Journal)
Source: Malaria Journal - May 25, 2017 Category: Infectious Diseases Authors: Paul N. Newton, Kara Hanson and Catherine Goodman Source Type: research

Glucose-6-phosphate dehydrogenase deficiency in people living in malaria endemic districts of Nepal
Glucose-6-phosphate dehydrogenase (G6PD) is a rate limiting enzyme of the pentose phosphate pathway and is closely associated with the haemolytic disorders among patients receiving anti-malarial drugs, such as... (Source: Malaria Journal)
Source: Malaria Journal - May 23, 2017 Category: Infectious Diseases Authors: Prakash Ghimire, Nihal Singh, Leonard Ortega, Komal Raj Rijal, Bipin Adhikari, Garib Das Thakur and Baburam Marasini Source Type: research

Molecular markers of anti-malarial drug resistance in Central, West and East African children with severe malaria
The Plasmodium falciparum multidrug resistance 1 (PfMDR1), P. falciparum Ca2+-ATPase (PfATP6) and Kelch-13 propeller domain (PfK13) loci are molecular markers of parasite susceptibility to anti-malarial drugs. Th... (Source: Malaria Journal)
Source: Malaria Journal - May 23, 2017 Category: Infectious Diseases Authors: Christian N. Nguetse, Ayola Akim Adegnika, Tsiri Agbenyega, Bernhards R. Ogutu, Sanjeev Krishna, Peter G. Kremsner and Thirumalaisamy P. Velavan Source Type: research

Intermittent preventive treatment for malaria among children in a refugee camp in Northern Uganda: lessons learned
Northern Uganda hosts a large population of refugees from South Sudan, and malaria is one of the major health problems in the area. In 2015, intermittent preventive treatment for malaria (IPTc) was implemented... (Source: Malaria Journal)
Source: Malaria Journal - May 23, 2017 Category: Infectious Diseases Authors: Matthew E. Coldiron, Estrella Lasry, Malika Bouhenia, Debashish Das, Peter Okui, Dan Nyehangane, Juliet Mwanga, Celine Langendorf, Greg Elder, L éon Salumu and Rebecca F. Grais Source Type: research

Within-host selection of drug resistance in a mouse model of repeated interrupted treatment of Plasmodium yoelii infection
To study within-host selection of resistant parasites, an important factor in the development of resistance to anti-malarial drugs, a mouse model of repeated interrupted malaria treatment (RIT) has been develo... (Source: Malaria Journal)
Source: Malaria Journal - May 23, 2017 Category: Infectious Diseases Authors: Suci Nuralitha, Josephine E. Siregar, Din Syafruddin, Andy I. M. Hoepelman and Sangkot Marzuki Source Type: research

Safety and tolerability of adjunctive rosiglitazone treatment for children with uncomplicated malaria
Despite the widespread use and availability of rapidly acting anti-malarials, the fatality rate of severe malaria in sub-Saharan Africa remains high. Adjunctive therapies that target the host response to malar... (Source: Malaria Journal)
Source: Malaria Journal - May 23, 2017 Category: Infectious Diseases Authors: Rosauro Varo, Valerie M. Crowley, Antonio Sitoe, Lola Madrid, Lena Serghides, Rubao Bila, Helio Mucavele, Alfredo Mayor, Quique Bassat and Kevin C. Kain Source Type: research