New sequence variants detected at DXS10148, DXS10074 and DXS10134 loci
Publication date: January 2016 Source:Forensic Science International: Genetics, Volume 20 Author(s): Iva Gomes, António Brehm, Leonor Gusmão, Peter M. Schneider A great amount of population and forensic genetic data are available for X-STRs supporting the need for having a common and accurate nomenclature among laboratories allowing for better communication, data exchange, and data comparison. DXS10148, DXS10074 and DXS10134 are commonly used X-STRs particularly due to their inclusion in the commercial kit Investigator Argus X-12 (Qiagen). Samples from West Africa and Iraq were sequenced for all three X-STRs ...
Source: Forensic Science International: Genetics - November 17, 2015 Category: Forensic Medicine Source Type: research
A Review of the Geographical Distribution and Habitat of the Atlantic Humpback Dolphin (Sousa teuszii).
Abstract
Understanding of the distributional ecology of the Atlantic humpback dolphin (Sousa teuszii) has been hampered by a lack of systematic and consistent sampling effort. The only comprehensive species distribution review was published in 2004; since then a considerable amount of novel information has emerged. We compiled 853 sighting, capture and specimen records of the species, and produced global and regional distribution maps. Of the 830 records where year was available, 63.1% dated from ≥2005 and confirm a contemporary occurrence in six marine ecoregions and 11 countries: Western Sahara, Maurit...
Source: Advances in Marine Biology - November 13, 2015 Category: Biology Authors: Weir CR, Collins T Tags: Adv Mar Biol Source Type: research
Predicting the extinction of HIV-2 in rural Guinea-Bissau
Conclusion: HIV-2 is predicted go extinct in Caió during the second half of this century. (Source: AIDS)
Source: AIDS - November 13, 2015 Category: Infectious Diseases Tags: Epidemiology and Social Source Type: research
Reduced All-cause Child Mortality After General Measles Vaccination Campaign in Rural Guinea-Bissau
Conclusions: Mortality levels were stable during 2004 and 2005, but a significant drop occurred after the 2006 MV campaign and was not explained by the prevention of measles deaths. If MV campaigns reduce nonmeasles-related mortality, the policies for measles vaccination should take this into account. (Source: The Pediatric Infectious Disease Journal)
Source: The Pediatric Infectious Disease Journal - November 13, 2015 Category: Infectious Diseases Tags: Vaccine Reports Source Type: research
Differential effects of sex in a West African cohort of HIV‐1, HIV‐2, and HIV‐1/2 infected patients: Men are worse off
ConclusionSignificant differences exist between HIV‐infected men and women regardless of HIV type. Men seek treatment at a later stage and, despite better socioeconomic status, have higher mortality and loss to follow‐up than women.This article is protected by copyright. All rights reserved. (Source: Tropical Medicine and International Health)
Source: Tropical Medicine and International Health - November 1, 2015 Category: Tropical Medicine Authors: Sanne Jespersen, Bo Langhoff Hønge, Joakim Esbjörnsson, Candida Medina, David da Silva Té, Faustino Gomes Correira, Alex Lund Laursen, Lars Østergaard, Andreas Andersen, Peter Aaby, Christian Erikstrup, Christian Wejse, Tags: Original Article Source Type: research
Assessing gender differences among tuberculosis suspects and patients in Guinea-Bissau
Conclusion: While more females searched help for symptoms indicating possible PTB disease, more males were diagnosed with PTB. There was no gender-difference in mortality during diagnostic work-up and outcome of subsequent TB treatment. (Source: European Respiratory Journal)
Source: European Respiratory Journal - October 30, 2015 Category: Respiratory Medicine Authors: Rudolf, F., Mendes, A. M., Blenstrup Pantsche, C., Sifna, A., Sargento Mendes, M., Gomes, V., Wejse, C. Tags: 10.2 Tuberculosis Source Type: research
The Effect of Oral Polio Vaccine at Birth on Infant Mortality: A Randomized Trial
Conclusions. This is the only randomized trial of the effect of OPV0 on mortality. OPV0 may be associated with nonspecific protection against infectious disease mortality, particularly when given early in life. There are reasons to monitor mortality when OPV is being phased out.
Clinical Trials Registration. NCT00710983. (Source: Clinical Infectious Diseases)
Source: Clinical Infectious Diseases - October 22, 2015 Category: Infectious Diseases Authors: Lund, N., Andersen, A., Hansen, A. S. K., Jepsen, F. S., Barbosa, A., Biering-Sorensen, S., Rodrigues, A., Ravn, H., Aaby, P., Benn, C. S. Tags: ARTICLES AND COMMENTARIES Source Type: research
Counterfeit antiepileptic drugs threaten community services in Guinea-Bissau and Nigeria
Publication date: November 2015 Source:The Lancet Neurology, Volume 14, Issue 11 Author(s): Willem M Otte, Eric van Diessen, Pieter van Eijsden, Frank van der Maas, Philip N Patsalos, Paul N Newton, Inácio C Alvarenga, Kees P Braun, Josemir W Sander (Source: The Lancet Neurology)
Source: The Lancet Neurology - October 20, 2015 Category: Neurology Source Type: research
[Correspondence] Counterfeit antiepileptic drugs threaten community services in Guinea-Bissau and Nigeria
Falsified drugs are a serious, yet vastly underreported, health-care hazard.1 Despite stringent regulations, counterfeit medications are becoming an increasing threat in low-income and lower-middle-income countries. Production of falsified drugs remains financially rewarding and largely risk-free because of inadequate law enforcement.1 We want to bring to the attention of the neurological community that promising efforts to address the huge epilepsy treatment gap in rural sub-Saharan Africa are being undermined by counterfeit antiepileptic drugs (AEDs). (Source: Lancet Neurology)
Source: Lancet Neurology - October 12, 2015 Category: Neurology Authors: Willem M Otte, Eric van Diessen, Pieter van Eijsden, Frank van der Maas, Philip N Patsalos, Paul N Newton, Inácio C Alvarenga, Kees P Braun, Josemir W Sander Tags: Correspondence Source Type: research
Lack of awareness of treatment failure among HIV-1-infected patients in Guinea-Bissau - a retrospective cohort study.
CONCLUSIONS: We found a high rate of treatment failure, an alarmingly high number of patients for whom treatment failure could not be assessed, and a low rate of switching to a second-line therapy. These factors could lead to an increased risk of resistance development and excess mortality.
PMID: 26426197 [PubMed - in process] (Source: Journal of the International AIDS Society)
Source: Journal of the International AIDS Society - October 3, 2015 Category: Infectious Diseases Tags: J Int AIDS Soc Source Type: research
Tuberculin reaction and BCG scar: Association with infant mortality
ConclusionWe confirmed previous observations that having a scar and a TST response after BCG vaccination is associated with lower mortality risk. The possibility of revaccinating scar negative children should be considered.This article is protected by copyright. All rights reserved. (Source: Tropical Medicine and International Health)
Source: Tropical Medicine and International Health - October 1, 2015 Category: Tropical Medicine Authors: Clara Amalie Gade Timmermann, Sofie Biering‐Sørensen, Peter Aaby, Ane Bærent Fisker, Ivan Monteiro, Amabelia Rodrigues, Christine Stabell Benn, Henrik Ravn Tags: Original Article Source Type: research
Early BCG vaccine to low-birth-weight infants and the effects on growth in the first year of life: a randomised controlled trial
Conclusion:
Though BCG vaccination is not recommended to be given to LBW infants at birth in Guinea-Bissau, early BCG had no negative effect on infant growth and may have had a beneficial effect for girls.Trial registration numberClinicalTrials.gov (NCT00146302). (Source: BMC Pediatrics)
Source: BMC Pediatrics - September 28, 2015 Category: Pediatrics Authors: Sofie Biering-SørensenAndreas AndersenHenrik RavnIvan MonterioPeter AabyChristine Benn Source Type: research
Snakebite is Under Appreciated: Appraisal of Burden from West Africa
Conclusions The public health burden of SBE in WA is very substantial and similar to other more widely recognized NTDs. Efforts and funding commensurate with its burden should be made available for the control of snakebite in the sub-region. (Source: PLoS Neglected Tropical Diseases)
Source: PLoS Neglected Tropical Diseases - September 23, 2015 Category: Tropical Medicine Authors: Abdulrazaq G. Habib et al. Source Type: research
Green turtle (Chelonia mydas) genetic diversity at Paranaguá Estuarine Complex feeding grounds in Brazil
Sea turtles are marine reptiles that undertake long migrations through their life, with limited information regarding juvenile stages. Feeding grounds (FGs), where they spend most of their lives, are composed by individuals from different natal origins, known as mixed stock populations. The aim of this study was to assess genetic composition, natal origins and demographic history of juvenile green turtles (Chelonia mydas) at the Paranaguá Estuarine Complex (PEC), Brazil, considered a Natural World Heritage site. Tissue samples of stranded animals were collected (n = 60), and 700 bp mitochondrial DNA sequences were generat...
Source: Genetics and Molecular Biology - September 16, 2015 Category: Genetics & Stem Cells Source Type: research
Analytical evaluation of nine serological assays for diagnosis of syphilis
ConclusionsIn resourced settings, where the reverse sequence algorithm is preferred for screening, an automated treponemal immunoassay for initial screening subsequently followed by the TrepSure test or TP‐PA assay as a second treponemal assay appear highly effective. Finally, a quantitative highly sensitive non‐treponemal assay, e.g. the Macro‐Vue RPR Card test, could then be used as a supplementary test to evaluate activity of the syphilis infection. (Source: Journal of the European Academy of Dermatology and Venereology)
Source: Journal of the European Academy of Dermatology and Venereology - September 14, 2015 Category: Dermatology Authors: K. Malm, S. Andersson, H. Fredlund, H. Norrgren, A. Biague, F. Månsson, R. Ballard, M. Unemo Tags: Original Article Source Type: research
