Art at the intersection of near-death experience
Publication date: Available online 15 November 2018Source: The Lancet NeurologyAuthor(s): Paul Kiet Tang (Source: The Lancet Neurology)
Source: The Lancet Neurology - November 16, 2018 Category: Neurology Source Type: research

Competing to raise awareness of rare diseases
Publication date: Available online 15 November 2018Source: The Lancet NeurologyAuthor(s): Agata Polizzi, Amalia Egle Gentile, Domenica Taruscio (Source: The Lancet Neurology)
Source: The Lancet Neurology - November 15, 2018 Category: Neurology Source Type: research

“No, actually it is not a headache”
Publication date: Available online 15 November 2018Source: The Lancet NeurologyAuthor(s): Jules Morgan (Source: The Lancet Neurology)
Source: The Lancet Neurology - November 15, 2018 Category: Neurology Source Type: research

Towards faster studies of neonatal encephalopathy
Publication date: Available online 15 November 2018Source: The Lancet NeurologyAuthor(s): Alistair J Gunn, Malcolm Battin (Source: The Lancet Neurology)
Source: The Lancet Neurology - November 15, 2018 Category: Neurology Source Type: research

Magnetic resonance spectroscopy assessment of brain injury after moderate hypothermia in neonatal encephalopathy: a prospective multicentre cohort study
Publication date: Available online 15 November 2018Source: The Lancet NeurologyAuthor(s): Peter J Lally, Paolo Montaldo, Vânia Oliveira, Aung Soe, Ravi Swamy, Paul Bassett, Josephine Mendoza, Gaurav Atreja, Ujwal Kariholu, Santosh Pattnayak, Palaniappan Sashikumar, Helen Harizaj, Martin Mitchell, Vijayakumar Ganesh, Sundeep Harigopal, Jennifer Dixon, Philip English, Paul Clarke, Priya Muthukumar, Prakash SatodiaSummaryBackgroundIn neonatal encephalopathy, the clinical manifestations of injury can only be reliably assessed several years after an intervention, complicating early prognostication and rendering trials of ...
Source: The Lancet Neurology - November 15, 2018 Category: Neurology Source Type: research

Will Europe be ready for the treatment of Alzheimer's disease?
Publication date: December 2018Source: The Lancet Neurology, Volume 17, Issue 12Author(s): The Lancet Neurology (Source: The Lancet Neurology)
Source: The Lancet Neurology - November 15, 2018 Category: Neurology Source Type: research

Bacterial meningitis: more can be done
Publication date: December 2018Source: The Lancet Neurology, Volume 17, Issue 12Author(s): James J Sejvar (Source: The Lancet Neurology)
Source: The Lancet Neurology - November 15, 2018 Category: Neurology Source Type: research

LRP10 in α-synucleinopathies
Publication date: December 2018Source: The Lancet Neurology, Volume 17, Issue 12Author(s): Demis A Kia, Marya S Sabir, Sarah Ahmed, Joanne Trinh, Sara Bandres-Ciga, Alastair J Noyce, Rauan Kaiyrzhanov, Ben Middlehurst, Demis A Kia, Manuela Tan, Henry Houlden, Huw R Morris, Helene Plun-Favreau, Peter Holmans, John Hardy, Daniah Trabzuni, Jose Bras, John Quinn, Kin Y Mok, Kerri J. Kinghorn (Source: The Lancet Neurology)
Source: The Lancet Neurology - November 15, 2018 Category: Neurology Source Type: research

LRP10 in α-synucleinopathies
Publication date: December 2018Source: The Lancet Neurology, Volume 17, Issue 12Author(s): Lasse Pihlstrøm, Lucia Schottlaender, Viorica Chelban, Henry Houlden, Safa Al-Sarraj, Thomas Arzberger, Conceicao Bettencourt, Kailash Bhatia, Dennis W Dickson, Monica Federoff, Ellen Gelpi, Steve Gentleman, John Hardy, Janice Holton, Inge Huitinga, Allan Levey, David Mann, Wassilios Meissner, Huw Morris, Chris Morris (Source: The Lancet Neurology)
Source: The Lancet Neurology - November 15, 2018 Category: Neurology Source Type: research

LRP10 in α-synucleinopathies
Publication date: December 2018Source: The Lancet Neurology, Volume 17, Issue 12Author(s): Christelle Tesson, Christine Brefel-Courbon, Jean-Christophe Corvol, Suzanne Lesage, Alexis Brice, Yves Agid, Mathieu Anheim, A.-M. Bonnet, Michel Borg, Christine Brefel-Courbon, Alexis Brice, Emmanuel Broussolle, Jean-Christophe Corvol, Philippe Damier, Alain Destée, Alexandra Dürr, Franck Durif, Suzanne Lesage, Ebba Lohmann, Maria Martinez (Source: The Lancet Neurology)
Source: The Lancet Neurology - November 15, 2018 Category: Neurology Source Type: research

LRP10 in α-synucleinopathies
Publication date: December 2018Source: The Lancet Neurology, Volume 17, Issue 12Author(s): Chang-He Shi, Hai-Yang Luo, Yu Fan, Yu-Sheng Li, Yu-Ming Xu (Source: The Lancet Neurology)
Source: The Lancet Neurology - November 15, 2018 Category: Neurology Source Type: research

LRP10 in α-synucleinopathies – Authors' reply
Publication date: December 2018Source: The Lancet Neurology, Volume 17, Issue 12Author(s): Marialuisa Quadri, Wim Mandemakers, Demy Kuipers, Guido J Breedveld, Vincenzo Bonifati (Source: The Lancet Neurology)
Source: The Lancet Neurology - November 15, 2018 Category: Neurology Source Type: research

150 years since Charcot's lectures on multiple sclerosis
Publication date: December 2018Source: The Lancet Neurology, Volume 17, Issue 12Author(s): Catherine Lubetzki (Source: The Lancet Neurology)
Source: The Lancet Neurology - November 15, 2018 Category: Neurology Source Type: research

Sylvain Rheims
Publication date: December 2018Source: The Lancet Neurology, Volume 17, Issue 12Author(s): (Source: The Lancet Neurology)
Source: The Lancet Neurology - November 15, 2018 Category: Neurology Source Type: research

Global, regional, and national burden of meningitis, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016
Publication date: December 2018Source: The Lancet Neurology, Volume 17, Issue 12Author(s): Joseph Raymond Zunt, Nicholas J Kassebaum, Natacha Blake, Linda Glennie, Claire Wright, Emma Nichols, Foad Abd-Allah, Jemal Abdela, Ahmed Abdelalim, Abdu A Adamu, Mina G. Adib, Alireza Ahmadi, Muktar Beshir Ahmed, Amani Nidhal Aichour, Ibtihel Aichour, Miloud Taki Eddine Aichour, Nadia Akseer, Rajaa M Al-Raddadi, Fares Alahdab, Kefyalew Addis AleneSummaryBackgroundAcute meningitis has a high case-fatality rate and survivors can have severe lifelong disability. We aimed to provide a comprehensive assessment of the levels and trends of...
Source: The Lancet Neurology - November 15, 2018 Category: Neurology Source Type: research

The role of plasminogen activators in stroke treatment: fibrinolysis and beyond
Publication date: December 2018Source: The Lancet Neurology, Volume 17, Issue 12Author(s): Audrey M Thiebaut, Maxime Gauberti, Carine Ali, Sara Martinez De Lizarrondo, Denis Vivien, Manuel Yepes, Benoit D RousselSummaryAlthough recent technical advances in thrombectomy have revolutionised acute stroke treatment, prevalence of disability and death related to stroke remain high. Therefore, plasminogen activators—eukaryotic, bacterial, or engineered forms that can promote fibrinolysis by converting plasminogen into active plasmin and facilitate clot breakdown—are still commonly used in the acute treatment of ischa...
Source: The Lancet Neurology - November 15, 2018 Category: Neurology Source Type: research

LRP10 in α-synucleinopathies
Publication date: December 2018Source: The Lancet Neurology, Volume 17, Issue 12Author(s): Rita Guerreiro, Tatiana Orme, João Luís Neto, Jose Bras, Rita Guerreiro, John Hardy, Celia Kun-Rodrigues, Lee Darwent, Tatiana Orme, Joao Neto, Susana Carmona, Olaf Ansorge, Laura Parkkinen, Kevin Morgan, Kristelle Brown, Anne Braae, Imelda Barber, Claire Troakes, Safa Al-Sarraj, Tammaryn Lashley (Source: The Lancet Neurology)
Source: The Lancet Neurology - November 15, 2018 Category: Neurology Source Type: research

Bryan Traynor: serious science from a funny fellow
Publication date: Available online 12 November 2018Source: The Lancet NeurologyAuthor(s): Ruth Williams (Source: The Lancet Neurology)
Source: The Lancet Neurology - November 14, 2018 Category: Neurology Source Type: research

The rise of neurology in Haiti
Publication date: Available online 8 November 2018Source: The Lancet NeurologyAuthor(s): Jacquelyn Corley (Source: The Lancet Neurology)
Source: The Lancet Neurology - November 9, 2018 Category: Neurology Source Type: research

Timing of anticoagulation after recent ischaemic stroke in patients with atrial fibrillation
Publication date: Available online 8 November 2018Source: The Lancet NeurologyAuthor(s): David J Seiffge, David J Werring, Maurizio Paciaroni, Jesse Dawson, Steven Warach, Truman J Milling, Stefan T Engelter, Urs Fischer, Bo NorrvingSummaryBackgroundAbout 13–26% of all acute ischaemic strokes are related to non-valvular atrial fibrillation, the most common cardiac arrhythmia globally. Deciding when to initiate oral anticoagulation in patients with non-valvular atrial fibrillation is a longstanding, common, and unresolved clinical challenge. Although the risk of early recurrent ischaemic stroke is high in this populat...
Source: The Lancet Neurology - November 9, 2018 Category: Neurology Source Type: research

The art of memory
Publication date: Available online 6 November 2018Source: The Lancet NeurologyAuthor(s): Jack Williamson (Source: The Lancet Neurology)
Source: The Lancet Neurology - November 7, 2018 Category: Neurology Source Type: research

Patients with large brain infarcts might also benefit from thrombectomy
Publication date: Available online 6 November 2018Source: The Lancet NeurologyAuthor(s): Steven Warach (Source: The Lancet Neurology)
Source: The Lancet Neurology - November 7, 2018 Category: Neurology Source Type: research

Penumbral imaging and functional outcome in patients with anterior circulation ischaemic stroke treated with endovascular thrombectomy versus medical therapy: a meta-analysis of individual patient-level data
Publication date: Available online 6 November 2018Source: The Lancet NeurologyAuthor(s): Bruce C V Campbell, Charles B L M Majoie, Gregory W Albers, Bijoy K Menon, Nawaf Yassi, Gagan Sharma, Wim H van Zwam, Robert J van Oostenbrugge, Andrew M Demchuk, Francis Guillemin, Philip White, Antoni Dávalos, Aad van der Lugt, Kenneth S Butcher, Aboubaker Cherifi, Henk A Marquering, Geoffrey Cloud, Juan M Macho Fernández, Jeremy Madigan, Catherine OppenheimSummaryBackgroundCT perfusion (CTP) and diffusion or perfusion MRI might assist patient selection for endovascular thrombectomy. We aimed to establish whether imagin...
Source: The Lancet Neurology - November 7, 2018 Category: Neurology Source Type: research

Global, regional, and national burden of motor neuron diseases 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016
Publication date: Available online 5 November 2018Source: The Lancet NeurologyAuthor(s): Giancarlo Logroscino, Marco Piccininni, Benoît Marin, Emma Nichols, Foad Abd-Allah, Ahmed Abdelalim, Fares Alahdab, Solomon Weldegebreal Asgedom, Ashish Awasthi, Yazan Chaiah, Ahmad Daryani, Huyen Phuc Do, Manisha Dubey, Alexis Elbaz, Sharareh Eskandarieh, Farzaneh Farhadi, Farshad Farzadfar, Seyed-Mohammad Fereshtehnejad, Eduarda Fernandes, Irina FilipSummaryBackgroundUnderstanding how prevalence, incidence, and mortality of motor neuron diseases change over time and by location is crucial for understanding the causes of these d...
Source: The Lancet Neurology - November 6, 2018 Category: Neurology Source Type: research

Global burden of motor neuron diseases: mind the gaps
Publication date: Available online 5 November 2018Source: The Lancet NeurologyAuthor(s): Orla Hardiman (Source: The Lancet Neurology)
Source: The Lancet Neurology - November 6, 2018 Category: Neurology Source Type: research

Correction to Lancet Neurol 2018; 17: 895–904
Publication date: Available online 26 October 2018Source: The Lancet NeurologyAuthor(s): (Source: The Lancet Neurology)
Source: The Lancet Neurology - October 27, 2018 Category: Neurology Source Type: research

Stroke–heart syndrome: clinical presentation and underlying mechanisms
Publication date: Available online 26 October 2018Source: The Lancet NeurologyAuthor(s): Jan F Scheitz, Christian H Nolte, Wolfram Doehner, Vladimir Hachinski, Matthias EndresSummaryCardiac complications are a frequent medical problem during the first few days after an ischaemic stroke, and patients present with a broad range of symptoms including myocardial injury, cardiac dysfunction, and arrhythmia, with varying overlap between these three conditions. Evidence from clinical and neuroimaging studies and animal research suggests that these cardiac disturbances share the same underlying mechanisms. Although the exact casca...
Source: The Lancet Neurology - October 27, 2018 Category: Neurology Source Type: research

Bart de Strooper: views from the rooftop
Publication date: Available online 23 October 2018Source: The Lancet NeurologyAuthor(s): Adrian Burton (Source: The Lancet Neurology)
Source: The Lancet Neurology - October 24, 2018 Category: Neurology Source Type: research

Correction to Lancet Neurol 2018; published online Sept 28. http://doi.org/10.1016/S1474-4422(18)30319-3
Publication date: Available online 23 October 2018Source: The Lancet NeurologyAuthor(s): (Source: The Lancet Neurology)
Source: The Lancet Neurology - October 24, 2018 Category: Neurology Source Type: research

Circadian rhythm and epilepsy
Publication date: Available online 23 October 2018Source: The Lancet NeurologyAuthor(s): Sofia Khan, Lino Nobili, Ramin Khatami, Tobias Loddenkemper, Christian Cajochen, Prof Derk-Jan Dijk, Sofia H ErikssonSummaryAdvances in diagnostic technology, including chronic intracranial EEG recordings, have confirmed the clinical observation of different temporal patterns of epileptic activity and seizure occurrence over a 24-h period. The rhythmic patterns in epileptic activity and seizure occurrence are probably related to vigilance states and circadian variation in excitatory and inhibitory balance. Core circadian genes BMAL1 an...
Source: The Lancet Neurology - October 24, 2018 Category: Neurology Source Type: research

Stephen Waxman: pioneer in axons, their disorders, and pain
Publication date: Available online 22 October 2018Source: The Lancet NeurologyAuthor(s): Tony Kirby (Source: The Lancet Neurology)
Source: The Lancet Neurology - October 23, 2018 Category: Neurology Source Type: research

Sleepyhead: Narcolepsy, Neuroscience and the Search for a Good Night, Henry Nicholls. Profile Books, London, UK (2018), 352, £16·99, ISBN: 978-1781255872
Publication date: Available online 18 October 2018Source: The Lancet NeurologyAuthor(s): Helena M Schotland (Source: The Lancet Neurology)
Source: The Lancet Neurology - October 20, 2018 Category: Neurology Source Type: research

Towards better management of the most vulnerable brains
Publication date: November 2018Source: The Lancet Neurology, Volume 17, Issue 11Author(s): The Lancet Neurology (Source: The Lancet Neurology)
Source: The Lancet Neurology - October 19, 2018 Category: Neurology Source Type: research

GBD 2016: still no improvement in the burden of migraine
Publication date: November 2018Source: The Lancet Neurology, Volume 17, Issue 11Author(s): Uwe Reuter (Source: The Lancet Neurology)
Source: The Lancet Neurology - October 19, 2018 Category: Neurology Source Type: research

Corrections
Publication date: November 2018Source: The Lancet Neurology, Volume 17, Issue 11Author(s): (Source: The Lancet Neurology)
Source: The Lancet Neurology - October 19, 2018 Category: Neurology Source Type: research

Response to the growing dementia burden must be broader
Publication date: November 2018Source: The Lancet Neurology, Volume 17, Issue 11Author(s): Werner Hacke, Vladimir Hachinski (Source: The Lancet Neurology)
Source: The Lancet Neurology - October 19, 2018 Category: Neurology Source Type: research

Making Maiken Nedergaard
Publication date: November 2018Source: The Lancet Neurology, Volume 17, Issue 11Author(s): Adrian Burton (Source: The Lancet Neurology)
Source: The Lancet Neurology - October 19, 2018 Category: Neurology Source Type: research

Ophir Keret
Publication date: November 2018Source: The Lancet Neurology, Volume 17, Issue 11Author(s): (Source: The Lancet Neurology)
Source: The Lancet Neurology - October 19, 2018 Category: Neurology Source Type: research

Soundscapes of the mind
Publication date: November 2018Source: The Lancet Neurology, Volume 17, Issue 11Author(s): Emilia Harding (Source: The Lancet Neurology)
Source: The Lancet Neurology - October 19, 2018 Category: Neurology Source Type: research

Global, regional, and national burden of migraine and tension-type headache, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016
Publication date: November 2018Source: The Lancet Neurology, Volume 17, Issue 11Author(s): Lars Jacob Stovner, Emma Nichols, Timothy J Steiner, Foad Abd-Allah, Ahmed Abdelalim, Rajaa M Al-Raddadi, Mustafa Geleto Ansha, Aleksandra Barac, Isabela M Bensenor, Linh Phuong Doan, Dumessa Edessa, Matthias Endres, Kyle J Foreman, Fortune Gbetoho Gankpe, Gururaj Gopalkrishna, Alessandra C Goulart, Rahul Gupta, Graeme J Hankey, Simon I Hay, Mohamed I HegazySummaryBackgroundThrough the Global Burden of Diseases, Injuries, and Risk Factors (GBD) studies, headache has emerged as a major global public health concern. We aimed to use dat...
Source: The Lancet Neurology - October 19, 2018 Category: Neurology Source Type: research

The glymphatic pathway in neurological disorders
Publication date: November 2018Source: The Lancet Neurology, Volume 17, Issue 11Author(s): Martin Kaag Rasmussen, Humberto Mestre, Maiken NedergaardSummaryBackgroundThe glymphatic (glial-lymphatic) pathway is a fluid-clearance pathway identified in the rodent brain in 2012. This pathway subserves the flow of CSF into the brain along arterial perivascular spaces and subsequently into the brain interstitium, facilitated by aquaporin 4 (AQP4) water channels. The pathway then directs flow towards the venous perivascular and perineuronal spaces, ultimately clearing solutes from the neuropil into meningeal and cervical lymphatic...
Source: The Lancet Neurology - October 19, 2018 Category: Neurology Source Type: research

Optimal stroke prevention in patients with patent foramen ovale
Publication date: Available online 16 October 2018Source: The Lancet NeurologyAuthor(s): Bernhard Meier (Source: The Lancet Neurology)
Source: The Lancet Neurology - October 17, 2018 Category: Neurology Source Type: research

IGF-1 for spinal and bulbar muscular atrophy: hope and challenges
Publication date: Available online 15 October 2018Source: The Lancet NeurologyAuthor(s): Atsushi Hashizume, Masahisa Katsuno (Source: The Lancet Neurology)
Source: The Lancet Neurology - October 16, 2018 Category: Neurology Source Type: research

Safety, tolerability, and preliminary efficacy of an IGF-1 mimetic in patients with spinal and bulbar muscular atrophy: a randomised, placebo-controlled trial
Publication date: Available online 15 October 2018Source: The Lancet NeurologyAuthor(s): Christopher Grunseich, Ram Miller, Therese Swan, David J Glass, Mohamed El Mouelhi, Mara Fornaro, Olivier Petricoul, Igor Vostiar, Ronenn Roubenoff, Matthew N Meriggioli, Angela Kokkinis, Robert D Guber, Maher S Budron, John Vissing, Gianni Soraru, Tahseen Mozaffar, Albert Ludolph, John T Kissel, Kenneth H Fischbeck, Christopher GrunseichSummaryBackgroundSpinal and bulbar muscular atrophy is an X-linked neuromuscular disease caused by CAG repeat expansion in the androgen receptor gene. Patients with this disease have low concentrations...
Source: The Lancet Neurology - October 16, 2018 Category: Neurology Source Type: research

Adventures in Memory: The Science and Secrets of Remembering and Forgetting, Hilde Østby, Ylva Østby. Greystone Books, Vancouver, Canada (2018), 296, CA$29.95, ISBN: 978-1771643474
Publication date: Available online 15 October 2018Source: The Lancet NeurologyAuthor(s): Robert Stirrups (Source: The Lancet Neurology)
Source: The Lancet Neurology - October 16, 2018 Category: Neurology Source Type: research

Argentina's unanswered stroke health-care question
Publication date: Available online 15 October 2018Source: The Lancet NeurologyAuthor(s): Adrian Burton (Source: The Lancet Neurology)
Source: The Lancet Neurology - October 16, 2018 Category: Neurology Source Type: research

Lessons from the Lobster: Eve Marder's Work in Neuroscience, Charlotte Nassim. The MIT Press, Cambridge, MA, USA (2018), 244, £22.00, ISBN: 978-0-262-03778-5
Publication date: Available online 8 October 2018Source: The Lancet NeurologyAuthor(s): Chris Wortley (Source: The Lancet Neurology)
Source: The Lancet Neurology - October 9, 2018 Category: Neurology Source Type: research

Rivaroxaban or aspirin for patent foramen ovale and embolic stroke of undetermined source: a prespecified subgroup analysis from the NAVIGATE ESUS trial
Publication date: Available online 28 September 2018Source: The Lancet NeurologyAuthor(s): Scott E Kasner, Balakumar Swaminathan, Pablo Lavados, Mukul Sharma, Keith Muir, Roland Veltkamp, Sebastian F Ameriso, Matthias Endres, Helmi Lutsep, Steven R Messé, J David Spence, Krassen Nedeltechev, Kanjana Perera, Gustavo Santo, Veronica Olavarria, Arne Lindgren, Shrikant Bangdiwala, Ashkan Shoamanesh, Scott D Berkowitz, Hardi MundlSummaryBackgroundPatent foramen ovale (PFO) is a contributor to embolic stroke of undetermined source (ESUS). Subgroup analyses from previous studies suggest that anticoagulation could reduce re...
Source: The Lancet Neurology - October 5, 2018 Category: Neurology Source Type: research

Global, regional, and national burden of Parkinson's disease, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016
Publication date: Available online 1 October 2018Source: The Lancet NeurologyAuthor(s): E. Ray Dorsey, Alexis Elbaz, Emma Nichols, Foad Abd-Allah, Ahmed Abdelalim, Jose C. Adsuar, Mustafa Geleto Ansha, Carol Brayne, Jee-Young J Choi, Daniel Collado-Mateo, Nabila Dahodwala, Huyen Phuc Do, Dumessa Edessa, Matthias Endres, Seyed-Mohammad Fereshtehnejad, Kyle J Foreman, Fortune Gbetoho Gankpe, Rahul Gupta, Graeme J. Hankey, Simon I. HaySummaryBackgroundNeurological disorders are now the leading source of disability globally, and ageing is increasing the burden of neurodegenerative disorders, including Parkinson's disease. We a...
Source: The Lancet Neurology - October 5, 2018 Category: Neurology Source Type: research

The burden of Parkinson's disease: a worldwide perspective
Publication date: Available online 1 October 2018Source: The Lancet NeurologyAuthor(s): Walter A Rocca (Source: The Lancet Neurology)
Source: The Lancet Neurology - October 5, 2018 Category: Neurology Source Type: research