An evaluation of assumptions underlying respondent-driven sampling and the social contexts of sexual and gender minority youth participating in HIV clinical trials in the United States
CONCLUSIONS: Small social networks and varying relationships with peers among BLSGMY challenge assumptions that underlie traditional RDS. Modified RDS approaches, including those that incorporate social media, may support recruitment for community-based research but may challenge assumptions of reciprocal relationships. Research hesitancy and situational barriers are relevant and must be addressed across any sampling method and study design that includes BLSGMY in the United States.PMID:33978326 | DOI:10.1002/jia2.25694 (Source: Journal of the International AIDS Society)
Source: Journal of the International AIDS Society - May 12, 2021 Category: Infectious Diseases Authors: Andrea L Wirtz Jessica R Iyer Durryle Brooks Kimberly Hailey-Fair Noya Galai Chris Beyrer David Celentano Renata Arrington-Sanders PUSH Study Group Source Type: research

HIV risk and pre-exposure prophylaxis interest among women seeking post-abortion care in Kenya: a cross-sectional study
CONCLUSIONS: Kenyan women accessing post-abortion care have substantial HIV risk and were favourable about the idea of receiving support to initiate PrEP as part of care offered during post-abortion care. These settings can be integrated into national PrEP programmes as locations providing PrEP referrals and initiation.PMID:33973355 | DOI:10.1002/jia2.25703 (Source: Journal of the International AIDS Society)
Source: Journal of the International AIDS Society - May 11, 2021 Category: Infectious Diseases Authors: Renee Heffron Edinah Casmir Linda Aswani Kenneth Ngure Benn Kwach Vallery Ogello Catherine Kiptinness Faith Ambiyo Njeri Wairimu Ethel Ossome Hilda Machafu Yasaman Zia Dorothy Thomas Caitlin Scoville Taryn Barker Elizabeth Bukusi Nelly Mugo Source Type: research

Adherence to event-driven HIV PrEP among men who have sex with men in Amsterdam, the Netherlands: analysis based on online diary data, 3-monthly questionnaires and intracellular TFV-DP
CONCLUSIONS: Adherence to edPrEP was high as determined from the online app and questionnaire. DBS measurements were consistent with two to three tablets per week on average.PMID:33973373 | DOI:10.1002/jia2.25708 (Source: Journal of the International AIDS Society)
Source: Journal of the International AIDS Society - May 11, 2021 Category: Infectious Diseases Authors: Vita W Jongen Elske Hoornenborg Mark Am van den Elshout Anders Boyd Hanne Ml Zimmermann Liza Coyer Udi Davidovich Peter L Anderson Henry Jc de Vries M Prins Maarten F Schim van der Loeff Amsterdam PrEP Project team in the HIV Transmission Elimination Amst Source Type: research

In memoriam: Charles Boucher (1958-2021)
J Int AIDS Soc. 2021 May;24(5):e25709. doi: 10.1002/jia2.25709.NO ABSTRACTPMID:33955168 | PMC:PMC8100387 | DOI:10.1002/jia2.25709 (Source: Journal of the International AIDS Society)
Source: Journal of the International AIDS Society - May 6, 2021 Category: Infectious Diseases Authors: Annette H Sohn Jonathan Schapiro Peter Reiss Source Type: research

A cluster-randomized controlled trial of a combination HIV risk reduction and microfinance intervention for female sex workers who use drugs in Kazakhstan
CONCLUSIONS: Compared to a combination HIVRR + MF intervention, a robust HIVRR intervention alone may be sufficient to reduce sexual and drug risk behaviours among FSW who use drugs. There may be structural limitations to the promise of microfinance for HIV risk reduction among this population.PMID:33955170 | PMC:PMC8100396 | DOI:10.1002/jia2.25682 (Source: Journal of the International AIDS Society)
Source: Journal of the International AIDS Society - May 6, 2021 Category: Infectious Diseases Authors: Nabila El-Bassel Tara McCrimmon Gaukhar Mergenova Mingway Chang Assel Terlikbayeva Sholpan Primbetova Azamat Kuskulov Bauyrzhan Baiserkin Alfiya Denebayeva Kulpan Kurmetova Susan S Witte Source Type: research

In memoriam: Charles Boucher (1958-2021)
J Int AIDS Soc. 2021 May;24(5):e25709. doi: 10.1002/jia2.25709.NO ABSTRACTPMID:33955168 | DOI:10.1002/jia2.25709 (Source: Journal of the International AIDS Society)
Source: Journal of the International AIDS Society - May 6, 2021 Category: Infectious Diseases Authors: Annette H Sohn Jonathan Schapiro Peter Reiss Source Type: research

A cluster-randomized controlled trial of a combination HIV risk reduction and microfinance intervention for female sex workers who use drugs in Kazakhstan
CONCLUSIONS: Compared to a combination HIVRR + MF intervention, a robust HIVRR intervention alone may be sufficient to reduce sexual and drug risk behaviours among FSW who use drugs. There may be structural limitations to the promise of microfinance for HIV risk reduction among this population.PMID:33955170 | DOI:10.1002/jia2.25682 (Source: Journal of the International AIDS Society)
Source: Journal of the International AIDS Society - May 6, 2021 Category: Infectious Diseases Authors: Nabila El-Bassel Tara McCrimmon Gaukhar Mergenova Mingway Chang Assel Terlikbayeva Sholpan Primbetova Azamat Kuskulov Bauyrzhan Baiserkin Alfiya Denebayeva Kulpan Kurmetova Susan S Witte Source Type: research

In memoriam: Charles Boucher (1958-2021)
J Int AIDS Soc. 2021 May;24(5):e25709. doi: 10.1002/jia2.25709.NO ABSTRACTPMID:33955168 | DOI:10.1002/jia2.25709 (Source: Journal of the International AIDS Society)
Source: Journal of the International AIDS Society - May 6, 2021 Category: Infectious Diseases Authors: Annette H Sohn Jonathan Schapiro Peter Reiss Source Type: research

A cluster-randomized controlled trial of a combination HIV risk reduction and microfinance intervention for female sex workers who use drugs in Kazakhstan
CONCLUSIONS: Compared to a combination HIVRR + MF intervention, a robust HIVRR intervention alone may be sufficient to reduce sexual and drug risk behaviours among FSW who use drugs. There may be structural limitations to the promise of microfinance for HIV risk reduction among this population.PMID:33955170 | DOI:10.1002/jia2.25682 (Source: Journal of the International AIDS Society)
Source: Journal of the International AIDS Society - May 6, 2021 Category: Infectious Diseases Authors: Nabila El-Bassel Tara McCrimmon Gaukhar Mergenova Mingway Chang Assel Terlikbayeva Sholpan Primbetova Azamat Kuskulov Bauyrzhan Baiserkin Alfiya Denebayeva Kulpan Kurmetova Susan S Witte Source Type: research

In memoriam: Charles Boucher (1958-2021)
J Int AIDS Soc. 2021 May;24(5):e25709. doi: 10.1002/jia2.25709.NO ABSTRACTPMID:33955168 | DOI:10.1002/jia2.25709 (Source: Journal of the International AIDS Society)
Source: Journal of the International AIDS Society - May 6, 2021 Category: Infectious Diseases Authors: Annette H Sohn Jonathan Schapiro Peter Reiss Source Type: research

A cluster-randomized controlled trial of a combination HIV risk reduction and microfinance intervention for female sex workers who use drugs in Kazakhstan
CONCLUSIONS: Compared to a combination HIVRR + MF intervention, a robust HIVRR intervention alone may be sufficient to reduce sexual and drug risk behaviours among FSW who use drugs. There may be structural limitations to the promise of microfinance for HIV risk reduction among this population.PMID:33955170 | DOI:10.1002/jia2.25682 (Source: Journal of the International AIDS Society)
Source: Journal of the International AIDS Society - May 6, 2021 Category: Infectious Diseases Authors: Nabila El-Bassel Tara McCrimmon Gaukhar Mergenova Mingway Chang Assel Terlikbayeva Sholpan Primbetova Azamat Kuskulov Bauyrzhan Baiserkin Alfiya Denebayeva Kulpan Kurmetova Susan S Witte Source Type: research

In memoriam: Charles Boucher (1958-2021)
J Int AIDS Soc. 2021 May;24(5):e25709. doi: 10.1002/jia2.25709.NO ABSTRACTPMID:33955168 | DOI:10.1002/jia2.25709 (Source: Journal of the International AIDS Society)
Source: Journal of the International AIDS Society - May 6, 2021 Category: Infectious Diseases Authors: Annette H Sohn Jonathan Schapiro Peter Reiss Source Type: research

A cluster-randomized controlled trial of a combination HIV risk reduction and microfinance intervention for female sex workers who use drugs in Kazakhstan
CONCLUSIONS: Compared to a combination HIVRR + MF intervention, a robust HIVRR intervention alone may be sufficient to reduce sexual and drug risk behaviours among FSW who use drugs. There may be structural limitations to the promise of microfinance for HIV risk reduction among this population.PMID:33955170 | DOI:10.1002/jia2.25682 (Source: Journal of the International AIDS Society)
Source: Journal of the International AIDS Society - May 6, 2021 Category: Infectious Diseases Authors: Nabila El-Bassel Tara McCrimmon Gaukhar Mergenova Mingway Chang Assel Terlikbayeva Sholpan Primbetova Azamat Kuskulov Bauyrzhan Baiserkin Alfiya Denebayeva Kulpan Kurmetova Susan S Witte Source Type: research

Is there a role for doravirine in African HIV treatment programmes? A large observational resistance study in South Africa
CONCLUSIONS: Although doravirine is approved as initial therapy in patients who are ART-naïve, it is currently recommended to obtain a genotype prior to the initiation of ART. Clinical studies are needed to ascertain whether predicted resistance profiles in ART naïve and NNRTI-treated patients translate into poor clinical outcomes, especially in settings where genotypic resistance testing is not available.PMID:33943000 | DOI:10.1002/jia2.25706 (Source: Journal of the International AIDS Society)
Source: Journal of the International AIDS Society - May 4, 2021 Category: Infectious Diseases Authors: Kim Steegen Michelle Moorhouse Annemarie Mj Wensing Willem Df Venter Lucia Hans Source Type: research

Characteristics of the HIV cascade of care and unsuppressed viral load among gay, bisexual and other men who have sex with men living with HIV across Canada's three largest cities
J Int AIDS Soc. 2021 Apr;24(4):e25699. doi: 10.1002/jia2.25699.ABSTRACTINTRODUCTION: Treatment as prevention strategies have been variously applied across provinces in Canada. We estimated HIV care cascade indicators and correlates of unsuppressed viral load (VL) among gay, bisexual and other men who have sex with men (GBM) recruited in Vancouver, Toronto and Montreal.METHODS: Sexually active GBM, aged ≥16 years, were recruited through respondent-driven sampling (RDS) from February 2017 to August 2019. Participants completed a Computer-Assisted Self-Interview and tests for HIV and other sexually transmitted infections (...
Source: Journal of the International AIDS Society - April 30, 2021 Category: Infectious Diseases Authors: David M Moore Zishan Cui Shayna Skakoon-Sparling Jordan Sang Justin Barath Lu Wang Nathan Lachowsky Joseph Cox Gilles Lambert Syed W Noor Daniel Grace Jody Jollimore Herak Apelian Allan Lal Abbie Parlette Trevor A Hart Source Type: research

A randomized controlled trial evaluating combination detection of HIV in Malawian sexually transmitted infections clinics
CONCLUSIONS: Combining three distinct HIV testing and referral strategies increased the detection of previously undiagnosed HIV infections within the socio-sexual networks of PLWH seeking STI care. Combination HIV detection strategies that leverage AHI screening and socio-sexual contact networks offer a novel and efficacious approach to increasing HIV status awareness.PMID:33929094 | DOI:10.1002/jia2.25701 (Source: Journal of the International AIDS Society)
Source: Journal of the International AIDS Society - April 30, 2021 Category: Infectious Diseases Authors: Jane S Chen Mitch Matoga Brian W Pence Kimberly A Powers Courtney N Maierhofer Edward Jere Cecilia Massa Shiraz Khan Sarah E Rutstein Sam Phiri Mina C Hosseinipour Myron S Cohen Irving F Hoffman William C Miller Kathryn E Lancaster Source Type: research

Characteristics of the HIV cascade of care and unsuppressed viral load among gay, bisexual and other men who have sex with men living with HIV across Canada's three largest cities
J Int AIDS Soc. 2021 Apr;24(4):e25699. doi: 10.1002/jia2.25699.ABSTRACTINTRODUCTION: Treatment as prevention strategies have been variously applied across provinces in Canada. We estimated HIV care cascade indicators and correlates of unsuppressed viral load (VL) among gay, bisexual and other men who have sex with men (GBM) recruited in Vancouver, Toronto and Montreal.METHODS: Sexually active GBM, aged ≥16 years, were recruited through respondent-driven sampling (RDS) from February 2017 to August 2019. Participants completed a Computer-Assisted Self-Interview and tests for HIV and other sexually transmitted infections (...
Source: Journal of the International AIDS Society - April 30, 2021 Category: Infectious Diseases Authors: David M Moore Zishan Cui Shayna Skakoon-Sparling Jordan Sang Justin Barath Lu Wang Nathan Lachowsky Joseph Cox Gilles Lambert Syed W Noor Daniel Grace Jody Jollimore Herak Apelian Allan Lal Abbie Parlette Trevor A Hart Source Type: research

A randomized controlled trial evaluating combination detection of HIV in Malawian sexually transmitted infections clinics
CONCLUSIONS: Combining three distinct HIV testing and referral strategies increased the detection of previously undiagnosed HIV infections within the socio-sexual networks of PLWH seeking STI care. Combination HIV detection strategies that leverage AHI screening and socio-sexual contact networks offer a novel and efficacious approach to increasing HIV status awareness.PMID:33929094 | DOI:10.1002/jia2.25701 (Source: Journal of the International AIDS Society)
Source: Journal of the International AIDS Society - April 30, 2021 Category: Infectious Diseases Authors: Jane S Chen Mitch Matoga Brian W Pence Kimberly A Powers Courtney N Maierhofer Edward Jere Cecilia Massa Shiraz Khan Sarah E Rutstein Sam Phiri Mina C Hosseinipour Myron S Cohen Irving F Hoffman William C Miller Kathryn E Lancaster Source Type: research

Characteristics of the HIV cascade of care and unsuppressed viral load among gay, bisexual and other men who have sex with men living with HIV across Canada's three largest cities
J Int AIDS Soc. 2021 Apr;24(4):e25699. doi: 10.1002/jia2.25699.ABSTRACTINTRODUCTION: Treatment as prevention strategies have been variously applied across provinces in Canada. We estimated HIV care cascade indicators and correlates of unsuppressed viral load (VL) among gay, bisexual and other men who have sex with men (GBM) recruited in Vancouver, Toronto and Montreal.METHODS: Sexually active GBM, aged ≥16 years, were recruited through respondent-driven sampling (RDS) from February 2017 to August 2019. Participants completed a Computer-Assisted Self-Interview and tests for HIV and other sexually transmitted infections (...
Source: Journal of the International AIDS Society - April 30, 2021 Category: Infectious Diseases Authors: David M Moore Zishan Cui Shayna Skakoon-Sparling Jordan Sang Justin Barath Lu Wang Nathan Lachowsky Joseph Cox Gilles Lambert Syed W Noor Daniel Grace Jody Jollimore Herak Apelian Allan Lal Abbie Parlette Trevor A Hart Source Type: research

A randomized controlled trial evaluating combination detection of HIV in Malawian sexually transmitted infections clinics
CONCLUSIONS: Combining three distinct HIV testing and referral strategies increased the detection of previously undiagnosed HIV infections within the socio-sexual networks of PLWH seeking STI care. Combination HIV detection strategies that leverage AHI screening and socio-sexual contact networks offer a novel and efficacious approach to increasing HIV status awareness.PMID:33929094 | DOI:10.1002/jia2.25701 (Source: Journal of the International AIDS Society)
Source: Journal of the International AIDS Society - April 30, 2021 Category: Infectious Diseases Authors: Jane S Chen Mitch Matoga Brian W Pence Kimberly A Powers Courtney N Maierhofer Edward Jere Cecilia Massa Shiraz Khan Sarah E Rutstein Sam Phiri Mina C Hosseinipour Myron S Cohen Irving F Hoffman William C Miller Kathryn E Lancaster Source Type: research

Characteristics of the HIV cascade of care and unsuppressed viral load among gay, bisexual and other men who have sex with men living with HIV across Canada's three largest cities
J Int AIDS Soc. 2021 Apr;24(4):e25699. doi: 10.1002/jia2.25699.ABSTRACTINTRODUCTION: Treatment as prevention strategies have been variously applied across provinces in Canada. We estimated HIV care cascade indicators and correlates of unsuppressed viral load (VL) among gay, bisexual and other men who have sex with men (GBM) recruited in Vancouver, Toronto and Montreal.METHODS: Sexually active GBM, aged ≥16 years, were recruited through respondent-driven sampling (RDS) from February 2017 to August 2019. Participants completed a Computer-Assisted Self-Interview and tests for HIV and other sexually transmitted infections (...
Source: Journal of the International AIDS Society - April 30, 2021 Category: Infectious Diseases Authors: David M Moore Zishan Cui Shayna Skakoon-Sparling Jordan Sang Justin Barath Lu Wang Nathan Lachowsky Joseph Cox Gilles Lambert Syed W Noor Daniel Grace Jody Jollimore Herak Apelian Allan Lal Abbie Parlette Trevor A Hart Source Type: research

A randomized controlled trial evaluating combination detection of HIV in Malawian sexually transmitted infections clinics
CONCLUSIONS: Combining three distinct HIV testing and referral strategies increased the detection of previously undiagnosed HIV infections within the socio-sexual networks of PLWH seeking STI care. Combination HIV detection strategies that leverage AHI screening and socio-sexual contact networks offer a novel and efficacious approach to increasing HIV status awareness.PMID:33929094 | DOI:10.1002/jia2.25701 (Source: Journal of the International AIDS Society)
Source: Journal of the International AIDS Society - April 30, 2021 Category: Infectious Diseases Authors: Jane S Chen Mitch Matoga Brian W Pence Kimberly A Powers Courtney N Maierhofer Edward Jere Cecilia Massa Shiraz Khan Sarah E Rutstein Sam Phiri Mina C Hosseinipour Myron S Cohen Irving F Hoffman William C Miller Kathryn E Lancaster Source Type: research

Comprehensive investigation of sources of misclassification errors in routine HIV testing in Zimbabwe
CONCLUSIONS: False-HIV-negative results were still common in Zimbabwe in 2017 and could be reduced with HIV testing algorithms that use RDTs with higher sensitivity under real-world conditions and greater practicality under busy clinic conditions, and by strengthening proficiency testing procedures in external quality assurance systems. New false-HIV-positive RDT results were infrequent but earlier errors in testing may have resulted in large numbers of uninfected individuals being on ART.PMID:33882190 | PMC:PMC8059712 | DOI:10.1002/jia2.25700 (Source: Journal of the International AIDS Society)
Source: Journal of the International AIDS Society - April 21, 2021 Category: Infectious Diseases Authors: Simon Gregson Louisa Moorhouse Tawanda Dadirai Haynes Sheppard Justin Mayini Nadine Beckmann Morten Skovdal Janet Dzangare Brian Moyo Rufurwokuda Maswera Benjamin A Pinsky Sungano Mharakurwa Ian Francis Owen Mugurungi Constance Nyamukapa Source Type: research

Comprehensive investigation of sources of misclassification errors in routine HIV testing in Zimbabwe
CONCLUSIONS: False-HIV-negative results were still common in Zimbabwe in 2017 and could be reduced with HIV testing algorithms that use RDTs with higher sensitivity under real-world conditions and greater practicality under busy clinic conditions, and by strengthening proficiency testing procedures in external quality assurance systems. New false-HIV-positive RDT results were infrequent but earlier errors in testing may have resulted in large numbers of uninfected individuals being on ART.PMID:33882190 | DOI:10.1002/jia2.25700 (Source: Journal of the International AIDS Society)
Source: Journal of the International AIDS Society - April 21, 2021 Category: Infectious Diseases Authors: Simon Gregson Louisa Moorhouse Tawanda Dadirai Haynes Sheppard Justin Mayini Nadine Beckmann Morten Skovdal Janet Dzangare Brian Moyo Rufurwokuda Maswera Benjamin A Pinsky Sungano Mharakurwa Ian Francis Owen Mugurungi Constance Nyamukapa Source Type: research

Weight gain before and after switch from TDF to TAF in a U.S. cohort study
CONCLUSIONS: In this large, diverse U.S. cohort of PLWH, switching from TDF to TAF was associated with pronounced weight gain immediately after switch, regardless of the core class or core agent, suggesting an independent effect of TAF on weight gain.PMID:33838004 | PMC:PMC8035674 | DOI:10.1002/jia2.25702 (Source: Journal of the International AIDS Society)
Source: Journal of the International AIDS Society - April 10, 2021 Category: Infectious Diseases Authors: Patrick Wg Mallon Laurence Brunet Ricky K Hsu Jennifer S Fusco Karam C Mounzer Girish Prajapati Andrew P Beyer Michael B Wohlfeiler Gregory P Fusco Source Type: research

"I just keep quiet about it and act as if everything is alright" - The cascade from trauma to disengagement among adolescents living with HIV in western Kenya
CONCLUSIONS: Trauma is a major factor underlying disengagement from HIV care among Kenyan adolescents. We describe a cascade of factors representing areas for intervention to support mental health and retention in HIV care. These include not only the provision of mental healthcare, but also preventing or addressing violence, trauma and stigma, and reinforcing social and familial support surrounding vulnerable adolescents. In this conceptualization, supporting retention in HIV care requires a trauma-informed approach, both in the individualized care of ALHIV and in the development of strategies and policies to support adole...
Source: Journal of the International AIDS Society - April 10, 2021 Category: Infectious Diseases Authors: Leslie A Enane Edith Apondi Mark Omollo Judith J Toromo Salim Bakari Josephine Aluoch Clemette Morris Rami Kantor Paula Braitstein J Dennis Fortenberry Winstone M Nyandiko Kara Wools-Kaloustian Batya Elul Rachel C Vreeman Source Type: research

Economic evaluation of differentiated service delivery models for HIV treatment in Lesotho: costs to providers and patients
CONCLUSIONS: Community-based, multi-month models of ART in Lesotho are likely to produce small cost savings to treatment providers and large savings to patients in Lesotho. Patient cost savings may support long-term adherence and retention in care.PMID:33838012 | PMC:PMC8035675 | DOI:10.1002/jia2.25692 (Source: Journal of the International AIDS Society)
Source: Journal of the International AIDS Society - April 10, 2021 Category: Infectious Diseases Authors: Brooke E Nichols Refiloe Cele Nkgomeleng Lekodeba Betty Tukei Nicoletta Ngorima-Mabhena Appolinaire Tiam Thapelo Maotoe Makatleho Veronica Sejana Iyiola O Faturiyele Charles Chasela Sydney Rosen Geoffrey Fatti Source Type: research

Weight gain before and after switch from TDF to TAF in a U.S. cohort study
CONCLUSIONS: In this large, diverse U.S. cohort of PLWH, switching from TDF to TAF was associated with pronounced weight gain immediately after switch, regardless of the core class or core agent, suggesting an independent effect of TAF on weight gain.PMID:33838004 | PMC:PMC8035674 | DOI:10.1002/jia2.25702 (Source: Journal of the International AIDS Society)
Source: Journal of the International AIDS Society - April 10, 2021 Category: Infectious Diseases Authors: Patrick Wg Mallon Laurence Brunet Ricky K Hsu Jennifer S Fusco Karam C Mounzer Girish Prajapati Andrew P Beyer Michael B Wohlfeiler Gregory P Fusco Source Type: research

"I just keep quiet about it and act as if everything is alright" - The cascade from trauma to disengagement among adolescents living with HIV in western Kenya
CONCLUSIONS: Trauma is a major factor underlying disengagement from HIV care among Kenyan adolescents. We describe a cascade of factors representing areas for intervention to support mental health and retention in HIV care. These include not only the provision of mental healthcare, but also preventing or addressing violence, trauma and stigma, and reinforcing social and familial support surrounding vulnerable adolescents. In this conceptualization, supporting retention in HIV care requires a trauma-informed approach, both in the individualized care of ALHIV and in the development of strategies and policies to support adole...
Source: Journal of the International AIDS Society - April 10, 2021 Category: Infectious Diseases Authors: Leslie A Enane Edith Apondi Mark Omollo Judith J Toromo Salim Bakari Josephine Aluoch Clemette Morris Rami Kantor Paula Braitstein J Dennis Fortenberry Winstone M Nyandiko Kara Wools-Kaloustian Batya Elul Rachel C Vreeman Source Type: research

Economic evaluation of differentiated service delivery models for HIV treatment in Lesotho: costs to providers and patients
CONCLUSIONS: Community-based, multi-month models of ART in Lesotho are likely to produce small cost savings to treatment providers and large savings to patients in Lesotho. Patient cost savings may support long-term adherence and retention in care.PMID:33838012 | PMC:PMC8035675 | DOI:10.1002/jia2.25692 (Source: Journal of the International AIDS Society)
Source: Journal of the International AIDS Society - April 10, 2021 Category: Infectious Diseases Authors: Brooke E Nichols Refiloe Cele Nkgomeleng Lekodeba Betty Tukei Nicoletta Ngorima-Mabhena Appolinaire Tiam Thapelo Maotoe Makatleho Veronica Sejana Iyiola O Faturiyele Charles Chasela Sydney Rosen Geoffrey Fatti Source Type: research

Weight gain before and after switch from TDF to TAF in a U.S. cohort study
CONCLUSIONS: In this large, diverse U.S. cohort of PLWH, switching from TDF to TAF was associated with pronounced weight gain immediately after switch, regardless of the core class or core agent, suggesting an independent effect of TAF on weight gain.PMID:33838004 | PMC:PMC8035674 | DOI:10.1002/jia2.25702 (Source: Journal of the International AIDS Society)
Source: Journal of the International AIDS Society - April 10, 2021 Category: Infectious Diseases Authors: Patrick Wg Mallon Laurence Brunet Ricky K Hsu Jennifer S Fusco Karam C Mounzer Girish Prajapati Andrew P Beyer Michael B Wohlfeiler Gregory P Fusco Source Type: research

"I just keep quiet about it and act as if everything is alright" - The cascade from trauma to disengagement among adolescents living with HIV in western Kenya
CONCLUSIONS: Trauma is a major factor underlying disengagement from HIV care among Kenyan adolescents. We describe a cascade of factors representing areas for intervention to support mental health and retention in HIV care. These include not only the provision of mental healthcare, but also preventing or addressing violence, trauma and stigma, and reinforcing social and familial support surrounding vulnerable adolescents. In this conceptualization, supporting retention in HIV care requires a trauma-informed approach, both in the individualized care of ALHIV and in the development of strategies and policies to support adole...
Source: Journal of the International AIDS Society - April 10, 2021 Category: Infectious Diseases Authors: Leslie A Enane Edith Apondi Mark Omollo Judith J Toromo Salim Bakari Josephine Aluoch Clemette Morris Rami Kantor Paula Braitstein J Dennis Fortenberry Winstone M Nyandiko Kara Wools-Kaloustian Batya Elul Rachel C Vreeman Source Type: research

Economic evaluation of differentiated service delivery models for HIV treatment in Lesotho: costs to providers and patients
CONCLUSIONS: Community-based, multi-month models of ART in Lesotho are likely to produce small cost savings to treatment providers and large savings to patients in Lesotho. Patient cost savings may support long-term adherence and retention in care.PMID:33838012 | PMC:PMC8035675 | DOI:10.1002/jia2.25692 (Source: Journal of the International AIDS Society)
Source: Journal of the International AIDS Society - April 10, 2021 Category: Infectious Diseases Authors: Brooke E Nichols Refiloe Cele Nkgomeleng Lekodeba Betty Tukei Nicoletta Ngorima-Mabhena Appolinaire Tiam Thapelo Maotoe Makatleho Veronica Sejana Iyiola O Faturiyele Charles Chasela Sydney Rosen Geoffrey Fatti Source Type: research

Weight gain before and after switch from TDF to TAF in a U.S. cohort study
CONCLUSIONS: In this large, diverse U.S. cohort of PLWH, switching from TDF to TAF was associated with pronounced weight gain immediately after switch, regardless of the core class or core agent, suggesting an independent effect of TAF on weight gain.PMID:33838004 | PMC:PMC8035674 | DOI:10.1002/jia2.25702 (Source: Journal of the International AIDS Society)
Source: Journal of the International AIDS Society - April 10, 2021 Category: Infectious Diseases Authors: Patrick Wg Mallon Laurence Brunet Ricky K Hsu Jennifer S Fusco Karam C Mounzer Girish Prajapati Andrew P Beyer Michael B Wohlfeiler Gregory P Fusco Source Type: research

"I just keep quiet about it and act as if everything is alright" - The cascade from trauma to disengagement among adolescents living with HIV in western Kenya
CONCLUSIONS: Trauma is a major factor underlying disengagement from HIV care among Kenyan adolescents. We describe a cascade of factors representing areas for intervention to support mental health and retention in HIV care. These include not only the provision of mental healthcare, but also preventing or addressing violence, trauma and stigma, and reinforcing social and familial support surrounding vulnerable adolescents. In this conceptualization, supporting retention in HIV care requires a trauma-informed approach, both in the individualized care of ALHIV and in the development of strategies and policies to support adole...
Source: Journal of the International AIDS Society - April 10, 2021 Category: Infectious Diseases Authors: Leslie A Enane Edith Apondi Mark Omollo Judith J Toromo Salim Bakari Josephine Aluoch Clemette Morris Rami Kantor Paula Braitstein J Dennis Fortenberry Winstone M Nyandiko Kara Wools-Kaloustian Batya Elul Rachel C Vreeman Source Type: research

Economic evaluation of differentiated service delivery models for HIV treatment in Lesotho: costs to providers and patients
CONCLUSIONS: Community-based, multi-month models of ART in Lesotho are likely to produce small cost savings to treatment providers and large savings to patients in Lesotho. Patient cost savings may support long-term adherence and retention in care.PMID:33838012 | PMC:PMC8035675 | DOI:10.1002/jia2.25692 (Source: Journal of the International AIDS Society)
Source: Journal of the International AIDS Society - April 10, 2021 Category: Infectious Diseases Authors: Brooke E Nichols Refiloe Cele Nkgomeleng Lekodeba Betty Tukei Nicoletta Ngorima-Mabhena Appolinaire Tiam Thapelo Maotoe Makatleho Veronica Sejana Iyiola O Faturiyele Charles Chasela Sydney Rosen Geoffrey Fatti Source Type: research

Weight gain before and after switch from TDF to TAF in a U.S. cohort study
CONCLUSIONS: In this large, diverse U.S. cohort of PLWH, switching from TDF to TAF was associated with pronounced weight gain immediately after switch, regardless of the core class or core agent, suggesting an independent effect of TAF on weight gain.PMID:33838004 | PMC:PMC8035674 | DOI:10.1002/jia2.25702 (Source: Journal of the International AIDS Society)
Source: Journal of the International AIDS Society - April 10, 2021 Category: Infectious Diseases Authors: Patrick Wg Mallon Laurence Brunet Ricky K Hsu Jennifer S Fusco Karam C Mounzer Girish Prajapati Andrew P Beyer Michael B Wohlfeiler Gregory P Fusco Source Type: research

"I just keep quiet about it and act as if everything is alright" - The cascade from trauma to disengagement among adolescents living with HIV in western Kenya
CONCLUSIONS: Trauma is a major factor underlying disengagement from HIV care among Kenyan adolescents. We describe a cascade of factors representing areas for intervention to support mental health and retention in HIV care. These include not only the provision of mental healthcare, but also preventing or addressing violence, trauma and stigma, and reinforcing social and familial support surrounding vulnerable adolescents. In this conceptualization, supporting retention in HIV care requires a trauma-informed approach, both in the individualized care of ALHIV and in the development of strategies and policies to support adole...
Source: Journal of the International AIDS Society - April 10, 2021 Category: Infectious Diseases Authors: Leslie A Enane Edith Apondi Mark Omollo Judith J Toromo Salim Bakari Josephine Aluoch Clemette Morris Rami Kantor Paula Braitstein J Dennis Fortenberry Winstone M Nyandiko Kara Wools-Kaloustian Batya Elul Rachel C Vreeman Source Type: research

Economic evaluation of differentiated service delivery models for HIV treatment in Lesotho: costs to providers and patients
CONCLUSIONS: Community-based, multi-month models of ART in Lesotho are likely to produce small cost savings to treatment providers and large savings to patients in Lesotho. Patient cost savings may support long-term adherence and retention in care.PMID:33838012 | PMC:PMC8035675 | DOI:10.1002/jia2.25692 (Source: Journal of the International AIDS Society)
Source: Journal of the International AIDS Society - April 10, 2021 Category: Infectious Diseases Authors: Brooke E Nichols Refiloe Cele Nkgomeleng Lekodeba Betty Tukei Nicoletta Ngorima-Mabhena Appolinaire Tiam Thapelo Maotoe Makatleho Veronica Sejana Iyiola O Faturiyele Charles Chasela Sydney Rosen Geoffrey Fatti Source Type: research

Weight gain before and after switch from TDF to TAF in a U.S. cohort study
CONCLUSIONS: In this large, diverse U.S. cohort of PLWH, switching from TDF to TAF was associated with pronounced weight gain immediately after switch, regardless of the core class or core agent, suggesting an independent effect of TAF on weight gain.PMID:33838004 | DOI:10.1002/jia2.25702 (Source: Journal of the International AIDS Society)
Source: Journal of the International AIDS Society - April 10, 2021 Category: Infectious Diseases Authors: Patrick Wg Mallon Laurence Brunet Ricky K Hsu Jennifer S Fusco Karam C Mounzer Girish Prajapati Andrew P Beyer Michael B Wohlfeiler Gregory P Fusco Source Type: research

"I just keep quiet about it and act as if everything is alright" - The cascade from trauma to disengagement among adolescents living with HIV in western Kenya
CONCLUSIONS: Trauma is a major factor underlying disengagement from HIV care among Kenyan adolescents. We describe a cascade of factors representing areas for intervention to support mental health and retention in HIV care. These include not only the provision of mental healthcare, but also preventing or addressing violence, trauma and stigma, and reinforcing social and familial support surrounding vulnerable adolescents. In this conceptualization, supporting retention in HIV care requires a trauma-informed approach, both in the individualized care of ALHIV and in the development of strategies and policies to support adole...
Source: Journal of the International AIDS Society - April 10, 2021 Category: Infectious Diseases Authors: Leslie A Enane Edith Apondi Mark Omollo Judith J Toromo Salim Bakari Josephine Aluoch Clemette Morris Rami Kantor Paula Braitstein J Dennis Fortenberry Winstone M Nyandiko Kara Wools-Kaloustian Batya Elul Rachel C Vreeman Source Type: research

Economic evaluation of differentiated service delivery models for HIV treatment in Lesotho: costs to providers and patients
CONCLUSIONS: Community-based, multi-month models of ART in Lesotho are likely to produce small cost savings to treatment providers and large savings to patients in Lesotho. Patient cost savings may support long-term adherence and retention in care.PMID:33838012 | DOI:10.1002/jia2.25692 (Source: Journal of the International AIDS Society)
Source: Journal of the International AIDS Society - April 10, 2021 Category: Infectious Diseases Authors: Brooke E Nichols Refiloe Cele Nkgomeleng Lekodeba Betty Tukei Nicoletta Ngorima-Mabhena Appolinaire Tiam Thapelo Maotoe Makatleho Veronica Sejana Iyiola O Faturiyele Charles Chasela Sydney Rosen Geoffrey Fatti Source Type: research

Weight gain before and after switch from TDF to TAF in a U.S. cohort study
CONCLUSIONS: In this large, diverse U.S. cohort of PLWH, switching from TDF to TAF was associated with pronounced weight gain immediately after switch, regardless of the core class or core agent, suggesting an independent effect of TAF on weight gain.PMID:33838004 | DOI:10.1002/jia2.25702 (Source: Journal of the International AIDS Society)
Source: Journal of the International AIDS Society - April 10, 2021 Category: Infectious Diseases Authors: Patrick Wg Mallon Laurence Brunet Ricky K Hsu Jennifer S Fusco Karam C Mounzer Girish Prajapati Andrew P Beyer Michael B Wohlfeiler Gregory P Fusco Source Type: research