Long-term retention on antiretroviral treatment after enrolment in prevention of vertical HIV transmission services: a prospective cohort study in Dar es Salaam, Tanzania
CONCLUSIONS: ART attrition among women with HIV remains highest in the first year of enrolment in vertical transmission prevention services and declines markedly following a transition to chronic HIV care. Targeted interventions to improve ART continuity among women with HIV during and beyond prevention of vertical transmission are vital to ending paediatric HIV and keeping women and children alive and healthy.PMID:38332522 | PMC:PMC10853596 | DOI:10.1002/jia2.26186 (Source: Journal of the International AIDS Society)
Source: Journal of the International AIDS Society - February 9, 2024 Category: Infectious Diseases Authors: Roseline Faustine Urrio Goodluck Willey Lyatuu David Sando Michael J Mahande Emmanuel Philipo Helga Naburi Peter Lyaruu Amanda Kimonge Kasasi Mayogu Brenda Simba Ayoub Muhamed Kibao Michael Msangi Zangin Zeebari Gunnel Biberfeld Anna Mia Ekstr öm Charles Source Type: research

Body weight and blood pressure changes on dolutegravir-, efavirenz- or atazanavir-based antiretroviral therapy in Zimbabwe: a longitudinal study
CONCLUSIONS: Among PLHIV starting ART or switching to a new regimen, DTG-based ART was associated with larger weight gains and a substantial increase in the prevalence of high blood pressure. Routine weight and blood pressure measurement and interventions to lower blood pressure could benefit PLHIV on DTG-based ART. Further studies are needed to elucidate the mechanisms and reversibility of these changes after discontinuation of DTG.PMID:38332525 | PMC:PMC10853595 | DOI:10.1002/jia2.26216 (Source: Journal of the International AIDS Society)
Source: Journal of the International AIDS Society - February 9, 2024 Category: Infectious Diseases Authors: Tinei Shamu Matthias Egger Tinashe Mudzviti Cleophas Chimbetete Justen Manasa Nanina Anderegg Source Type: research

Healthcare provisions associated with multiple HIV-related outcomes among adolescent girls and young women living with HIV in South Africa: a cross-sectional study
CONCLUSIONS: Accessible and adolescent-responsive healthcare is critical to improving HIV-related outcomes, reducing morbidity, mortality and onward HIV transmission among AGYW. Combining these provisions can maximize benefits, especially for AGYW mothers.PMID:38332518 | PMC:PMC10853575 | DOI:10.1002/jia2.26212 (Source: Journal of the International AIDS Society)
Source: Journal of the International AIDS Society - February 9, 2024 Category: Infectious Diseases Authors: Elona Toska Siyanai Zhou Christina A Laurenzi Wylene Saal William Rudgard Camille Wittesaele Nontokozo Langwenya Janina Jochim Bolad é Hamed Banougnin Laurie Gulaid Alice Armstrong Gayle Sherman Olanrewaju Edun Lorraine Sherr Lucie Cluver Source Type: research

Temporal dynamics and drivers of durable HIV viral load suppression and persistent high- and low-level viraemia during Universal Test and Treat scale-up in Uganda: a population-based study
CONCLUSIONS: Following universal ART provision, most persons living with HIV in south-central Uganda are durably suppressed. Among persons exhibiting any viraemia, nearly half exhibited high-level viraemia for ≥12 months and reported higher-risk behaviours associated with onward HIV transmission. Intensified efforts linking individuals to HIV treatment services could accelerate momentum towards HIV epidemic control.PMID:38332519 | PMC:PMC10853573 | DOI:10.1002/jia2.26200 (Source: Journal of the International AIDS Society)
Source: Journal of the International AIDS Society - February 9, 2024 Category: Infectious Diseases Authors: Joseph Gregory Rosen Robert Ssekubugu Larry W Chang Victor Ssempijja Ronald M Galiwango Joseph Ssekasanvu Anthony Ndyanabo Alice Kisakye Gertrude Nakigozi Katherine B Rucinski Eshan U Patel Caitlin E Kennedy Fred Nalugoda Godfrey Kigozi Oliver Ratmann Lis Source Type: research

HIV pre-exposure prophylaxis programme preferences among sexually active HIV-negative transgender and gender diverse adults in the United States: a conjoint analysis
CONCLUSIONS: Participants preferred programmes that offered PrEP services without cost-sharing and bundled with gender-affirming hormone therapy services. Bolstering federal regulations to cover PrEP services and prioritizing programmes to expand low-barrier PrEP provision are critical to achieving equitable PrEP provision. Community-engaged implementation research conducted by and in close collaboration with trans community stakeholders and researchers are needed to streamline the design of patient-centred PrEP programmes and develop implementation strategies that are salient to the diverse sexual health needs of trans pa...
Source: Journal of the International AIDS Society - February 9, 2024 Category: Infectious Diseases Authors: Dovie L Watson Louis Listerud Ryan A Drab Willey Y Lin Florence Marie Momplaisir Jos é A Bauermeister Source Type: research

Long-term retention on antiretroviral treatment after enrolment in prevention of vertical HIV transmission services: a prospective cohort study in Dar es Salaam, Tanzania
CONCLUSIONS: ART attrition among women with HIV remains highest in the first year of enrolment in vertical transmission prevention services and declines markedly following a transition to chronic HIV care. Targeted interventions to improve ART continuity among women with HIV during and beyond prevention of vertical transmission are vital to ending paediatric HIV and keeping women and children alive and healthy.PMID:38332522 | PMC:PMC10853596 | DOI:10.1002/jia2.26186 (Source: Journal of the International AIDS Society)
Source: Journal of the International AIDS Society - February 9, 2024 Category: Infectious Diseases Authors: Roseline Faustine Urrio Goodluck Willey Lyatuu David Sando Michael J Mahande Emmanuel Philipo Helga Naburi Peter Lyaruu Amanda Kimonge Kasasi Mayogu Brenda Simba Ayoub Muhamed Kibao Michael Msangi Zangin Zeebari Gunnel Biberfeld Anna Mia Ekstr öm Charles Source Type: research

Body weight and blood pressure changes on dolutegravir-, efavirenz- or atazanavir-based antiretroviral therapy in Zimbabwe: a longitudinal study
CONCLUSIONS: Among PLHIV starting ART or switching to a new regimen, DTG-based ART was associated with larger weight gains and a substantial increase in the prevalence of high blood pressure. Routine weight and blood pressure measurement and interventions to lower blood pressure could benefit PLHIV on DTG-based ART. Further studies are needed to elucidate the mechanisms and reversibility of these changes after discontinuation of DTG.PMID:38332525 | PMC:PMC10853595 | DOI:10.1002/jia2.26216 (Source: Journal of the International AIDS Society)
Source: Journal of the International AIDS Society - February 9, 2024 Category: Infectious Diseases Authors: Tinei Shamu Matthias Egger Tinashe Mudzviti Cleophas Chimbetete Justen Manasa Nanina Anderegg Source Type: research

Healthcare provisions associated with multiple HIV-related outcomes among adolescent girls and young women living with HIV in South Africa: a cross-sectional study
CONCLUSIONS: Accessible and adolescent-responsive healthcare is critical to improving HIV-related outcomes, reducing morbidity, mortality and onward HIV transmission among AGYW. Combining these provisions can maximize benefits, especially for AGYW mothers.PMID:38332518 | PMC:PMC10853575 | DOI:10.1002/jia2.26212 (Source: Journal of the International AIDS Society)
Source: Journal of the International AIDS Society - February 9, 2024 Category: Infectious Diseases Authors: Elona Toska Siyanai Zhou Christina A Laurenzi Wylene Saal William Rudgard Camille Wittesaele Nontokozo Langwenya Janina Jochim Bolad é Hamed Banougnin Laurie Gulaid Alice Armstrong Gayle Sherman Olanrewaju Edun Lorraine Sherr Lucie Cluver Source Type: research

Temporal dynamics and drivers of durable HIV viral load suppression and persistent high- and low-level viraemia during Universal Test and Treat scale-up in Uganda: a population-based study
CONCLUSIONS: Following universal ART provision, most persons living with HIV in south-central Uganda are durably suppressed. Among persons exhibiting any viraemia, nearly half exhibited high-level viraemia for ≥12 months and reported higher-risk behaviours associated with onward HIV transmission. Intensified efforts linking individuals to HIV treatment services could accelerate momentum towards HIV epidemic control.PMID:38332519 | PMC:PMC10853573 | DOI:10.1002/jia2.26200 (Source: Journal of the International AIDS Society)
Source: Journal of the International AIDS Society - February 9, 2024 Category: Infectious Diseases Authors: Joseph Gregory Rosen Robert Ssekubugu Larry W Chang Victor Ssempijja Ronald M Galiwango Joseph Ssekasanvu Anthony Ndyanabo Alice Kisakye Gertrude Nakigozi Katherine B Rucinski Eshan U Patel Caitlin E Kennedy Fred Nalugoda Godfrey Kigozi Oliver Ratmann Lis Source Type: research

HIV pre-exposure prophylaxis programme preferences among sexually active HIV-negative transgender and gender diverse adults in the United States: a conjoint analysis
CONCLUSIONS: Participants preferred programmes that offered PrEP services without cost-sharing and bundled with gender-affirming hormone therapy services. Bolstering federal regulations to cover PrEP services and prioritizing programmes to expand low-barrier PrEP provision are critical to achieving equitable PrEP provision. Community-engaged implementation research conducted by and in close collaboration with trans community stakeholders and researchers are needed to streamline the design of patient-centred PrEP programmes and develop implementation strategies that are salient to the diverse sexual health needs of trans pa...
Source: Journal of the International AIDS Society - February 9, 2024 Category: Infectious Diseases Authors: Dovie L Watson Louis Listerud Ryan A Drab Willey Y Lin Florence Marie Momplaisir Jos é A Bauermeister Source Type: research

Long-term retention on antiretroviral treatment after enrolment in prevention of vertical HIV transmission services: a prospective cohort study in Dar es Salaam, Tanzania
CONCLUSIONS: ART attrition among women with HIV remains highest in the first year of enrolment in vertical transmission prevention services and declines markedly following a transition to chronic HIV care. Targeted interventions to improve ART continuity among women with HIV during and beyond prevention of vertical transmission are vital to ending paediatric HIV and keeping women and children alive and healthy.PMID:38332522 | PMC:PMC10853596 | DOI:10.1002/jia2.26186 (Source: Journal of the International AIDS Society)
Source: Journal of the International AIDS Society - February 9, 2024 Category: Infectious Diseases Authors: Roseline Faustine Urrio Goodluck Willey Lyatuu David Sando Michael J Mahande Emmanuel Philipo Helga Naburi Peter Lyaruu Amanda Kimonge Kasasi Mayogu Brenda Simba Ayoub Muhamed Kibao Michael Msangi Zangin Zeebari Gunnel Biberfeld Anna Mia Ekstr öm Charles Source Type: research

Body weight and blood pressure changes on dolutegravir-, efavirenz- or atazanavir-based antiretroviral therapy in Zimbabwe: a longitudinal study
CONCLUSIONS: Among PLHIV starting ART or switching to a new regimen, DTG-based ART was associated with larger weight gains and a substantial increase in the prevalence of high blood pressure. Routine weight and blood pressure measurement and interventions to lower blood pressure could benefit PLHIV on DTG-based ART. Further studies are needed to elucidate the mechanisms and reversibility of these changes after discontinuation of DTG.PMID:38332525 | PMC:PMC10853595 | DOI:10.1002/jia2.26216 (Source: Journal of the International AIDS Society)
Source: Journal of the International AIDS Society - February 9, 2024 Category: Infectious Diseases Authors: Tinei Shamu Matthias Egger Tinashe Mudzviti Cleophas Chimbetete Justen Manasa Nanina Anderegg Source Type: research

Healthcare provisions associated with multiple HIV-related outcomes among adolescent girls and young women living with HIV in South Africa: a cross-sectional study
CONCLUSIONS: Accessible and adolescent-responsive healthcare is critical to improving HIV-related outcomes, reducing morbidity, mortality and onward HIV transmission among AGYW. Combining these provisions can maximize benefits, especially for AGYW mothers.PMID:38332518 | PMC:PMC10853575 | DOI:10.1002/jia2.26212 (Source: Journal of the International AIDS Society)
Source: Journal of the International AIDS Society - February 9, 2024 Category: Infectious Diseases Authors: Elona Toska Siyanai Zhou Christina A Laurenzi Wylene Saal William Rudgard Camille Wittesaele Nontokozo Langwenya Janina Jochim Bolad é Hamed Banougnin Laurie Gulaid Alice Armstrong Gayle Sherman Olanrewaju Edun Lorraine Sherr Lucie Cluver Source Type: research

Temporal dynamics and drivers of durable HIV viral load suppression and persistent high- and low-level viraemia during Universal Test and Treat scale-up in Uganda: a population-based study
CONCLUSIONS: Following universal ART provision, most persons living with HIV in south-central Uganda are durably suppressed. Among persons exhibiting any viraemia, nearly half exhibited high-level viraemia for ≥12 months and reported higher-risk behaviours associated with onward HIV transmission. Intensified efforts linking individuals to HIV treatment services could accelerate momentum towards HIV epidemic control.PMID:38332519 | PMC:PMC10853573 | DOI:10.1002/jia2.26200 (Source: Journal of the International AIDS Society)
Source: Journal of the International AIDS Society - February 9, 2024 Category: Infectious Diseases Authors: Joseph Gregory Rosen Robert Ssekubugu Larry W Chang Victor Ssempijja Ronald M Galiwango Joseph Ssekasanvu Anthony Ndyanabo Alice Kisakye Gertrude Nakigozi Katherine B Rucinski Eshan U Patel Caitlin E Kennedy Fred Nalugoda Godfrey Kigozi Oliver Ratmann Lis Source Type: research

HIV pre-exposure prophylaxis programme preferences among sexually active HIV-negative transgender and gender diverse adults in the United States: a conjoint analysis
CONCLUSIONS: Participants preferred programmes that offered PrEP services without cost-sharing and bundled with gender-affirming hormone therapy services. Bolstering federal regulations to cover PrEP services and prioritizing programmes to expand low-barrier PrEP provision are critical to achieving equitable PrEP provision. Community-engaged implementation research conducted by and in close collaboration with trans community stakeholders and researchers are needed to streamline the design of patient-centred PrEP programmes and develop implementation strategies that are salient to the diverse sexual health needs of trans pa...
Source: Journal of the International AIDS Society - February 9, 2024 Category: Infectious Diseases Authors: Dovie L Watson Louis Listerud Ryan A Drab Willey Y Lin Florence Marie Momplaisir Jos é A Bauermeister Source Type: research