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[Neonatal Morbidity and Gestational Diabetes: Coincidence or Consequence of the 2011 Protocol].
CONCLUSION: To analyse national data will be fundamental to understand this unexpected increase in morbidity. PMID: 29025524 [PubMed - in process] (Source: Acta Medica Portuguesa)
Source: Acta Medica Portuguesa - October 16, 2017 Category: General Medicine Tags: Acta Med Port Source Type: research

[Translation and Validation of the FOUR Scale for Children and its Use as Outcome Predictor: A Pilot Study].
CONCLUSION: The FOUR scale can be applied in patients admitted with impaired consciousness in Pediatric Intensive Care Units. We think that a multicenter study would be very beneficial for confirming and generalizing these results. PMID: 29025525 [PubMed - in process] (Source: Acta Medica Portuguesa)
Source: Acta Medica Portuguesa - October 16, 2017 Category: General Medicine Tags: Acta Med Port Source Type: research

Hospital-Acquired Urinary Tract Infections: Results of a Cohort Study Performed in an Internal Medicine Department.
CONCLUSION: The high rate of catheter associated urinary tract infection that occurred in the absence of bladder placement indication reinforces the need to implement prevention strategies that contemplate the reduction of its use. Emergency departments should be part of quality improvement projects in this area. Causes for the early onset of catheter associated urinary tract infection in this cohort should be investigated. PMID: 29025526 [PubMed - in process] (Source: Acta Medica Portuguesa)
Source: Acta Medica Portuguesa - October 16, 2017 Category: General Medicine Tags: Acta Med Port Source Type: research

[Being a Mother After 35 Years: Will it be Different?]
This study aims to examine the relationship between advanced maternal age and their maternal and fetal consequences, as well as maternal perception of the risk of pregnancy after 35 years old. MATERIAL AND METHODS: Observational, retrospective and comparative study, between two groups: advanced maternal age group (aged ≥ 35 years) and non-advanced maternal age group (age
Source: Acta Medica Portuguesa - October 16, 2017 Category: General Medicine Tags: Acta Med Port Source Type: research

[Evaluation of the Function and Quality of Life after Total Hip Arthroplasty by Different Approaches].
CONCLUSION: After 24 months post total hip arthroplasty there are no differences between the two approaches with regard to function or quality of life. However, the patients operated by the anterolateral approach had greater muscle strength deficits and higher percentage of positive Trendelenburg test. PMID: 29025528 [PubMed - in process] (Source: Acta Medica Portuguesa)
Source: Acta Medica Portuguesa - October 16, 2017 Category: General Medicine Tags: Acta Med Port Source Type: research

[Volume or Value? The Role of the Radiologist in Managing Radiological Exams].
CONCLUSION: The radiologist can better manage the required radiological examinations, effectively screening within a multidisciplinary team environment, promoting the development and supporting the respect of guidelines, and potentially reducing requests through opinions or second opinions. PMID: 29025529 [PubMed - in process] (Source: Acta Medica Portuguesa)
Source: Acta Medica Portuguesa - October 16, 2017 Category: General Medicine Tags: Acta Med Port Source Type: research

Intensive Follow-Up After Curative Surgery for Colorectal Cancer.
Authors: Rodrigues RV, Pereira da Silva J, Rosa I, Santos I, Pereira N, Soares C, Pereira AD Abstract INTRODUCTION: The purpose of postoperative surveillance programs after curative treatment for colorectal cancer is to detect asymptomatic recurrences with the premise that an important rate will be eligible for curative resection, improving overall survival. We have implemented a surveillance program for patients with colorectal cancer, stages II-III, with periodic clinical, carcinoembryonic antigen and cancer antigen-19-9 assessment, computed tomography and colonoscopy. The aim of this study was to ...
Source: Acta Medica Portuguesa - October 16, 2017 Category: General Medicine Tags: Acta Med Port Source Type: research

[Endocrinology in Portugal - Census 2016. Board of the Portuguese College of Endocrinology and Nutrition of the Portuguese Medical Association].
CONCLUSION: In recent years, the number of residents has significantly increased, which will make it possible to correct this situation. PMID: 29025531 [PubMed - in process] (Source: Acta Medica Portuguesa)
Source: Acta Medica Portuguesa - October 16, 2017 Category: General Medicine Tags: Acta Med Port Source Type: research

Conflict of Interest Disclosure in a Top-Tier Portuguese Medical Journal.
CONCLUSION: The lack of concordance between self-reported conflicts of interest and payments found in the database raises concerns about incomplete disclosure. PMID: 29025532 [PubMed - in process] (Source: Acta Medica Portuguesa)
Source: Acta Medica Portuguesa - October 16, 2017 Category: General Medicine Tags: Acta Med Port Source Type: research

Negative βhCG and Molar Pregnancy: The Hook Effect.
We describe a case referred as a degenerating fibroid, with a negative urinary pregnancy test. Transvaginal ultrasound was highly suggestive of molar pregnancy, which was confirmed with a quantitative βhCG test, allowing for timely treatment. The importance of a high index of suspicion for this pathology is tremendous to avoid the devastating consequences of a delayed diagnosis. PMID: 29025533 [PubMed - in process] (Source: Acta Medica Portuguesa)
Source: Acta Medica Portuguesa - October 16, 2017 Category: General Medicine Tags: Acta Med Port Source Type: research

[Endovascular Treatment of a Gastroduodenal Artery Pseudoaneurysm Rupture after a Car Accident].
Authors: Dutra S, Gomes FV, Bilhim T, Coimbra É Abstract The authors present a case of a 39-year-old man with alcoholic chronic pancreatitis that was admitted in the emergency department after a car accident, complaining of abdominal pain and looking pale. The patient was hemodinamically unstable, requiring blood transfusions. He underwent computed tomography angiogram of the abdomen and pelvis, showing a pseudoaneurysm of the gastroduodenal artery and a hemoperitoneum. He was referred to our interventional radiology unit and submitted to endovascular treatment, consisting of 'backdoor' and 'frontdoor' embol...
Source: Acta Medica Portuguesa - October 16, 2017 Category: General Medicine Tags: Acta Med Port Source Type: research

Umbilical Cord Hemangioma with Pseudocyst: An Exceptional Finding.
Authors: Rocha A, Rodrigues MC, Braga J PMID: 29025535 [PubMed - in process] (Source: Acta Medica Portuguesa)
Source: Acta Medica Portuguesa - October 16, 2017 Category: General Medicine Tags: Acta Med Port Source Type: research

Foreign Bodies in Pediatrics: A Case to Say "Hello Kitty".
Foreign Bodies in Pediatrics: A Case to Say "Hello Kitty". Acta Med Port. 2017 Sep 29;30(9):663 Authors: Rodrigues M, Abreu L PMID: 29025536 [PubMed - in process] (Source: Acta Medica Portuguesa)
Source: Acta Medica Portuguesa - October 16, 2017 Category: General Medicine Tags: Acta Med Port Source Type: research

Letter to the Editor: Medication-Overuse Headache is Common in Portuguese Migraineurs.
Authors: Duarte Mendonça M, Caetano A, Salavisa M, Viana-Baptista M, Miguel R, Pinto M, Barbosa R, Ladeira F, Sá F, Pelejão R, CHLO Headache Study Group: PMID: 29025537 [PubMed - in process] (Source: Acta Medica Portuguesa)
Source: Acta Medica Portuguesa - October 16, 2017 Category: General Medicine Tags: Acta Med Port Source Type: research

Letter to the Editor: Maternally Inherited Diabetes and Deafness is Not Only Biorgan but Multiorgan.
Authors: Finsterer J, Zarrouk-Mahjoub S PMID: 29025538 [PubMed - in process] (Source: Acta Medica Portuguesa)
Source: Acta Medica Portuguesa - October 16, 2017 Category: General Medicine Tags: Acta Med Port Source Type: research

[Analysis of the Cochrane Review: Anti-vascular Endothelial Growth Factor for Prevention of Postoperative Vitreous Cavity Hemorrhage after Vitrectomy for Proliferative Diabetic Retinopathy. Cochrane Database Syst Rev. 2015;8:CD008214.]
Authors: Sousa DC, Leal I, Costa J, Vaz-Carneiro A Abstract Postoperative vitreous hemorrhage is a complication following vitrectomy for proliferative diabetic retinopathy, delaying visual recovery and making fundus examination and disease follow-up more difficult. Anti-vascular endothelial growth factor drugs such as bevacizumab, when injected in the vitreous cavity, reduce vascular proliferation and their use has been proposed to reduce the incidence of postoperative vitreous hemorrhage. The authors of this Cochrane systematic review evaluated all randomized controlled trials on the pre- or intraoperative use of ...
Source: Acta Medica Portuguesa - September 21, 2017 Category: General Medicine Tags: Acta Med Port Source Type: research

Treatment of Anorexia Nervosa: The Importance of Disease Progression in the Prognosis.
CONCLUSION: Our results support the idea that illness duration has an important role on the outcome and prognostic features of these patients. PMID: 28926324 [PubMed - in process] (Source: Acta Medica Portuguesa)
Source: Acta Medica Portuguesa - September 21, 2017 Category: General Medicine Tags: Acta Med Port Source Type: research

[Epidemiology of Internet Use by an Adolescent Population and its Relation with Sleep Habits].
The objectives of this study were to assess and characterize Internet use in adolescence, determine Internet addiction and clarify its association with sleep disorders and excessive daytime sleepiness. MATERIAL AND METHODS: It was performed an observational, cross sectional and community-based study. The target were students attending 7th and 8th grades, to whom was applied an online self-report questionnaire to assess sociodemographic features, Internet use, Internet dependence, sleep characteristics and excessive daytime sleepiness. RESULTS: A total of 727 adolescents were included with a mean age 13 ± 0.9...
Source: Acta Medica Portuguesa - September 21, 2017 Category: General Medicine Tags: Acta Med Port Source Type: research

Prevalence of Hepatitis A Virus Antibody in Portuguese Travelers: A New Paradigm.
CONCLUSION: Across age groups there is a trend towards lower prevalence of hepatitis A virus antibody, in particular among youngsters, when compared with older Portuguese studies. PMID: 28926326 [PubMed - in process] (Source: Acta Medica Portuguesa)
Source: Acta Medica Portuguesa - September 21, 2017 Category: General Medicine Tags: Acta Med Port Source Type: research

Long-Term Outcomes of the Calcaneo-Stop Procedure in the Treatment of Flexible Flatfoot in Children: A Retrospective Study.
CONCLUSION: Larger, prospective, controlled studies are required to better evaluate the long-term success of this procedure. PMID: 28926327 [PubMed - in process] (Source: Acta Medica Portuguesa)
Source: Acta Medica Portuguesa - September 21, 2017 Category: General Medicine Tags: Acta Med Port Source Type: research

[Morbidity in the Dependent Elderly Cared by Home-Teams of the National Network of Continued Integrated Care in the Lisbon and Tagus Valley: Cross-Sectional Study].
CONCLUSION: The population cared by the integrated continuing care teams is at risk: elderly, with low scholar degree level, with a high disease-burden and disability. PMID: 28926328 [PubMed - in process] (Source: Acta Medica Portuguesa)
Source: Acta Medica Portuguesa - September 21, 2017 Category: General Medicine Tags: Acta Med Port Source Type: research

Postoperative Haematocrit and Outcome in Critically Ill Surgical Patients.
Authors: Lopes AM, Silva D, Sousa G, Silva J, Santos A, Abelha FJ Abstract INTRODUCTION: Haematocrit has been studied as an outcome predictor. The aim of this study was to evaluate the correlation between low haematocrit at surgical intensive care unit admission and high disease scoring system score and early outcomes. MATERIAL AND METHODS: This retrospective study included 4398 patients admitted to the surgical intensive care unit between January 2006 and July 2013. Acute physiology and chronic health evaluation and simplified acute physiology score II values were calculated and all variables en...
Source: Acta Medica Portuguesa - September 21, 2017 Category: General Medicine Tags: Acta Med Port Source Type: research

[Diabetes: Socioeconomic Inequalities in the Portuguese Population in 2014].
CONCLUSION: Supporting 'Health in All Policies' might reduce inequalities, namely by improving population educational level and actions that promote health literacy. PMID: 28926330 [PubMed - in process] (Source: Acta Medica Portuguesa)
Source: Acta Medica Portuguesa - September 21, 2017 Category: General Medicine Tags: Acta Med Port Source Type: research

[Assessment of Urinary Incontinence in Pregnancy and Postpartum: Observational Study].
This study was designed in order to identify and assess the prevalence and risk factors for urinary incontinence during the third trimester of pregnancy and three months postpartum. MATERIAL AND METHODS: Observational and cross-sectional study. The population of the study was composed of 268 women who delivered and were admitted to the Centro Hospitalar Tâmega e Sousa in the years 2013 and 2014, and who agreed to participate in this study. Postpartum women were asked to fill out a questionnaire adapted from the International Consultation on Incontinence Questionnaire - Short Form, for urinary incontinence researc...
Source: Acta Medica Portuguesa - September 21, 2017 Category: General Medicine Tags: Acta Med Port Source Type: research

[Choroidal Melanoma].
Authors: Coutinho I, Teixeira T, Simões PC, Lopes JC, Borrego M, Fernandes J, Cabral J, Prieto I, Proença R Abstract Choroidal melanoma is the most common primary intraocular malignant tumor in adults. None of the different treatments available offers advantages of survival, resorting more and more to conservative treatments such as brachytherapy, which has been available in Portugal since 2013. In this article we review the clinical characteristics, risk factors, diagnosis, complementary exams and therapeutic options in choroidal melanoma. PMID: 28926332 [PubMed - in process] (Source: Acta Medica Portuguesa)
Source: Acta Medica Portuguesa - September 21, 2017 Category: General Medicine Tags: Acta Med Port Source Type: research

Pneumonitis in Adult Onset Still's Disease: Uncommon or Under Diagnosed?
Authors: Fernandes S, Almeida M, Pereira da Silva JA, Romeu JC Abstract The adult onset Still's Disease is an uncommon entity characterized by multiple clinical manifestations. Pneumonitis, less often considered, deserves particular emphasis given the need for differential diagnosis and because it can progress to severe respiratory failure. With the aim to highlight the pulmonary parenchyma involvement in patients with adult onset Still's Disease, we present a case report which progresses with pneumonitis. PMID: 28926333 [PubMed - in process] (Source: Acta Medica Portuguesa)
Source: Acta Medica Portuguesa - September 21, 2017 Category: General Medicine Tags: Acta Med Port Source Type: research

Family Phenotypic Heterogeneity Caused by Mitochondrial DNA Mutation A3243G.
Authors: Alves D, Calmeiro ME, Macário C, Silva R Abstract Maternally inherited diabetes and deafness is a rare form of diabetes caused by a mitochondrial DNA mutation. The index case is a 55-year-old woman who was admitted with hypertrophic cardiomyopathy. She had a history of diabetes mellitus and hearing loss. The patient's mother, two brothers and two sisters also had a history of diabetes and hearing loss. This pattern suggests a maternally inherited disorder. All siblings carried the A3243G mitochondrial DNA mutation. The identification of people with monogenic forms of diabetes mel...
Source: Acta Medica Portuguesa - September 21, 2017 Category: General Medicine Tags: Acta Med Port Source Type: research

[Generalized Bullous Eruption During Treatment with Vancomycin].
Authors: Pinho A, Cardoso JC PMID: 28926335 [PubMed - in process] (Source: Acta Medica Portuguesa)
Source: Acta Medica Portuguesa - September 21, 2017 Category: General Medicine Tags: Acta Med Port Source Type: research

Extensive Atypical HSV-2 Ulceration of the Finger.
Authors: Cunha N, Simões P, Serrão V PMID: 28926336 [PubMed - in process] (Source: Acta Medica Portuguesa)
Source: Acta Medica Portuguesa - September 21, 2017 Category: General Medicine Tags: Acta Med Port Source Type: research

Letter to the Editor regarding the article: "Vitamin D and Prevention of Chronic Diseases" by Ant ónio Vaz-Carneiro. Acta Med Port. 2017;30:351-3.
Letter to the Editor regarding the article: "Vitamin D and Prevention of Chronic Diseases" by António Vaz-Carneiro. Acta Med Port. 2017;30:351-3. Acta Med Port. 2017 Aug 31;30(7-8):588 Authors: Santos VM PMID: 28926337 [PubMed - in process] (Source: Acta Medica Portuguesa)
Source: Acta Medica Portuguesa - September 21, 2017 Category: General Medicine Tags: Acta Med Port Source Type: research

[Diabetes in Coronary Disease: The Risk of Non-Diagnosis].
Authors: Raposo JF PMID: 28898607 [PubMed - in process] (Source: Acta Medica Portuguesa)
Source: Acta Medica Portuguesa - September 13, 2017 Category: General Medicine Tags: Acta Med Port Source Type: research

[Health Governance and Proximity Management: The Need for Autonomy in Management in Primary Health Care Systems].
Authors: Firmino-Machado J, Magalhães I, Rodrigues J, Ramos V, Baptista S, Vilas-Boas B PMID: 28898608 [PubMed - in process] (Source: Acta Medica Portuguesa)
Source: Acta Medica Portuguesa - September 13, 2017 Category: General Medicine Tags: Acta Med Port Source Type: research

[Diabetes Screening in Patients with Macrovascular Coronary Disease: Are the New European Guidelines a Step Backwards?]
Authors: Ribeiro A, Baptista SB, Faustino M, Alves P, Abreu PF, Gil VM, Morais C Abstract BACKGROUND: The new European guidelines on diabetes mellitus and cardiovascular diseases propose that the FINnish Diabetes RIsk SCore should be used to evaluate the risk of diabetes mellitus and that diabetes mellitus screening in coronary artery disease patients should be based on fasting glucose and HbA1c. The 2 hour oral glucose tolerance test, recommended for all pts in the previous guidelines, is now only recommended for 'inconclusive' cases. We aimed to evaluate this new strategy. MATERIAL AND METHODS: Fasting glucos...
Source: Acta Medica Portuguesa - September 13, 2017 Category: General Medicine Tags: Acta Med Port Source Type: research

[Visceral Leishmaniasis in HIV-Infected Patients: The Challenge of Relapse and Treatment Failure].
Authors: Cipriano P, Miranda AC, Antunes I, Mansinho K Abstract INTRODUCTION: Visceral leishmaniasis is an endemic disseminated infection, considered to be the third most frequent opportunistic parasitic infection in Europe. It is especially prevalent in patients co-infected with human immunodeficiency virus, in whom it poses a great therapeutic challenge due to increased risk of relapse. The goal of this study is to characterize a population of co-infected patients, as well as the efficiency of the adopted treatment strategies. MATERIAL AND METHODS: Retrospective study with a sample composed of all patients wi...
Source: Acta Medica Portuguesa - September 13, 2017 Category: General Medicine Tags: Acta Med Port Source Type: research

A Retrospective Analysis of the Real-Life Utilization of Ranibizumab in Patients with Wet Age-Related Macular Degeneration from Portugal.
CONCLUSION: These findings indicate that as-needed treatment resulted in under-dosing in a real-life setting in Portugal. Such limitations may also be related to increasing numbers of patients, resulting in clinic saturation. PMID: 28898611 [PubMed - in process] (Source: Acta Medica Portuguesa)
Source: Acta Medica Portuguesa - September 13, 2017 Category: General Medicine Tags: Acta Med Port Source Type: research

[Paediatric Invasive Pneumococcal Disease Before Universal Vaccination: 1995 - 2015].
CONCLUSION: This retrospective analysis before universal vaccination will contribute to evaluate the impact of vaccination in the Portuguese pediatric population. PMID: 28898612 [PubMed - in process] (Source: Acta Medica Portuguesa)
Source: Acta Medica Portuguesa - September 13, 2017 Category: General Medicine Tags: Acta Med Port Source Type: research

Functional, Sensorial, Mobility and Communication Difficulties in the Portuguese Oldest Old (80+).
CONCLUSION: Based on the observed differences between centenarians and younger oldest old, specific interventions should be equated to better respond to their potentially distinctive needs. PMID: 28898613 [PubMed - in process] (Source: Acta Medica Portuguesa)
Source: Acta Medica Portuguesa - September 13, 2017 Category: General Medicine Tags: Acta Med Port Source Type: research

[Fine-needle Aspiration of Thyroid Nodules: Is it Worth Repeating?]
This study aims to evaluate the concordance of results in consecutive fine-needle aspiration and to study the relevance of repetition in benign results. MATERIAL AND METHODS: Retrospective study of the 4800 thyroid nodules fine-needle aspiration held in Instituto de Patologia e Imunologia Molecular da Universidade do Porto between January 1, 2014 and May 2, 2016. Of the initial sample, we selected the repeated fine-needle aspiration on the same nodule. RESULTS: The first fine-needle aspiration result of the 309 nodules underwent revaluation was non-diagnostic in 103 (33.3%), benign in 120 (38.8%) and atypia/follicu...
Source: Acta Medica Portuguesa - September 13, 2017 Category: General Medicine Tags: Acta Med Port Source Type: research

Breech Presentation: Vaginal Versus Cesarean Delivery, Which Intervention Leads to the Best Outcomes?
Authors: Fonseca A, Silva R, Rato I, Neves AR, Peixoto C, Ferraz Z, Ramalho I, Carocha A, Félix N, Valdoleiros S, Galvão A, Gonçalves D, Curado J, Palma MJ, Antunes IL, Clode N, Graça LM Abstract INTRODUCTION: The best route of delivery for the term breech fetus is still controversial. We aim to compare maternal and neonatal outcomes between vaginal and cesarean term breech deliveries. MATERIAL AND METHODS: Multicentric retrospective cohort study of singleton term breech fetuses delivered vaginally or by elective cesarean section from January 2012 - October 2014. Primary ou...
Source: Acta Medica Portuguesa - September 13, 2017 Category: General Medicine Tags: Acta Med Port Source Type: research

The Calcium/Phosphorus Homeostasis in Chronic Kidney Disease: From Clinical Epidemiology to Pathophysiology.
CONCLUSION: The clinical data analysis used permits to illustrate the underlying pathophysiological mechanisms. PMID: 28898616 [PubMed - in process] (Source: Acta Medica Portuguesa)
Source: Acta Medica Portuguesa - September 13, 2017 Category: General Medicine Tags: Acta Med Port Source Type: research

[Secondary Arterial Hypertension: Uncertainties in Diagnosis].
Authors: Dinis PG, Cachulo MC, Fernandes A, Paiva L, Gonçalves L Abstract Arterial hypertension is regarded today as a global public health problem, and the prevalence rate in Portugal is 26.9%. According to the etiology, is classified into primary or secondary arterial hypertension. In about 90% of cases it is not possible to establish a cause, so is called primary arterial hypertension. In the remaining 5 to 10%, it can be identified secondary causes, which are potentially treatable. For secondary arterial hypertension study to be cost-effective, it is essential to understand which patients investigate, an...
Source: Acta Medica Portuguesa - September 13, 2017 Category: General Medicine Tags: Acta Med Port Source Type: research

[Klebsiella pneumoniae from K1 and Hypervirulent Clone ST23: First Documented Case in Portugal].
Authors: Pereira A, Petrucci T, Simões MJ Abstract The hypervirulent K1 serotype Klebsiella pneumoniae is responsible for a new invasive syndrome, typically associated to hepatic abscesses with extra-hepatic complications. Initially described in Taiwan, it has significantly spread to several Asian countries and more recently to Europe and North America, thus constituting an emerging and global problem. The authors describe a case report of a 64-years-old portuguese caucasian woman without any previous diseases or epidemiological risk factors such as trips or contact with Asian products or population, diagnos...
Source: Acta Medica Portuguesa - September 13, 2017 Category: General Medicine Tags: Acta Med Port Source Type: research

Target Sign: Endoscopic Sign of the Colonic Perforation.
Authors: Costa JM, Soares JB PMID: 28898619 [PubMed - in process] (Source: Acta Medica Portuguesa)
Source: Acta Medica Portuguesa - September 13, 2017 Category: General Medicine Tags: Acta Med Port Source Type: research

[Fatal Hemoptysis].
Authors: Costa CG, Gama C PMID: 28898620 [PubMed - in process] (Source: Acta Medica Portuguesa)
Source: Acta Medica Portuguesa - September 13, 2017 Category: General Medicine Tags: Acta Med Port Source Type: research

[Investigation of Genetic Aetiology in Neurodegenerative Ataxias: Recommendations from the Group of Neurogenetics of Centro Hospitalar S ão João, Portugal].
[Investigation of Genetic Aetiology in Neurodegenerative Ataxias: Recommendations from the Group of Neurogenetics of Centro Hospitalar São João, Portugal]. Acta Med Port. 2017 Jun 30;30(6):502-512 Authors: Gomes T, Guimaraes J, Leão M, Grupo de Neurogenetica do Centro Hospitalar Sao Joao Abstract In recent decades, a long and increasing list of monogenic neurodegenerative ataxias has been identified, allowing for better characterization of the pathophysiology, phenotype and prognosis of this heterogeneous group of disorders, while also revealing potential new therapeutic targets. H...
Source: Acta Medica Portuguesa - September 13, 2017 Category: General Medicine Tags: Acta Med Port Source Type: research

[Vitamin D in the Prevention of Chronic Diseases: An Evidence Based Analysis].
Authors: Vaz-Carneiro A PMID: 28865496 [PubMed - in process] (Source: Acta Medica Portuguesa)
Source: Acta Medica Portuguesa - September 5, 2017 Category: General Medicine Tags: Acta Med Port Source Type: research

Exercise as an Essential Therapeutic Tool in Mental Health: Closing the Gap From Research to Practice, A Portuguese Perspective.
Authors: Carneiro L, Rosenbaum S, Mota MP, Schuch F, Ward PB, Vasconcelos-Raposo J PMID: 28865497 [PubMed - in process] (Source: Acta Medica Portuguesa)
Source: Acta Medica Portuguesa - September 5, 2017 Category: General Medicine Tags: Acta Med Port Source Type: research

[Analysis of the Cochrane Review: Pharmacotherapy for Hyperuricemia in Hypertensive Patients. Cochrane Database Syst Rev. 2017;4:CD008652.]
Authors: Bigotte Vieira M, Baptista RB, Costa J, Vaz-Carneiro A Abstract Arterial hypertension is a public health problem that affects approximately 25% of the world's adult population. The association between hypertension and hyperuricemia has been shown on epidemiological and experimental studies. However, it is unclear whether lowering serum uric acid might lower blood pressure. This Cochrane systematic review - a revised edition of a previously published one - intended as primary objective to evaluate the effect of hypouricemic drugs in patients with primary hypertension or prehypertension. The secondary object...
Source: Acta Medica Portuguesa - September 5, 2017 Category: General Medicine Tags: Acta Med Port Source Type: research

Association Between Weekend and Holiday Admission with Pneumonia and Mortality in a Tertiary Center in Portugal: A Cross-Sectional Study.
CONCLUSION: A weekend/holiday effect in acute bacterial pneumonia was not evident in our series. PMID: 28865499 [PubMed - in process] (Source: Acta Medica Portuguesa)
Source: Acta Medica Portuguesa - September 5, 2017 Category: General Medicine Tags: Acta Med Port Source Type: research

[Determinant Factors of Morbidity in Patients with Systemic Lupus Erythematosus].
Authors: Jacinto M, Silva E, Riso N, Moraes-Fontes MF Abstract INTRODUCTION: Severity in systemic lupus erythematosus may vary from mild to even fatal consequences. There are no biomarkers to predict the disease's prognosis. The Systemic Lupus International Collaborating Clinics/ Systemic Damage Index defines systemic lupus erythematosus disease severity and is found to predict prognosis. OBJECTIVE: To test damage determinants in a single-centre systemic lupus erythematosus cohort. MATERIAL AND METHODS: Retrospectively followed systemic lupus erythematosus female patients (defined by the identification of a...
Source: Acta Medica Portuguesa - September 5, 2017 Category: General Medicine Tags: Acta Med Port Source Type: research