Der p 1 ‐specific regulatory T cell response during house dust mite allergen immunotherapy
ConclusionThe results indicate that AIT involves upregulation of the activated allergen ‐specific Treg cells and downregulation of dysfunctional allergen‐specific Treg cells subset. Correction of dysregulated Treg cells responses during AIT is associated with improved clinical response.This article is protected by copyright. All rights reserved. (Source: Allergy)
Source: Allergy - November 28, 2018 Category: Allergy & Immunology Authors: Tadech Boonpiyathad, Milena Sokolowska, Hideaki Morita, Beate R ückert, Jeannette I Kast, Marcin Wawrzyniak, Atik Sangasapaviliya, Panitan Pradubpongsa, Rattanaporn Fuengthong, Pattarawat Thantiworasit, Sunee Sirivichayakul, William W. Kwok, Tags: Original Article: Experimental Allergy and Immunology Source Type: research

Omalizumab discontinuation in children with severe allergic asthma: an observational real life study
Allergy, Volume 0, Issue ja, -Not available-. (Source: Allergy)
Source: Allergy - November 27, 2018 Category: Allergy & Immunology Authors: A Deschildre, J. Roussel, E Drumez, R Abou ‐Taam, C Rames, P Le Roux, G Pouessel, M Scalbert, C Bonnel,, S Mitha, S Boileau, C Mordacq, C Thumerelle, J Labreuche, S Lejeune, C Marguet Tags: Letter to the Editor Source Type: research

Distinct Lipid Transfer Proteins display different IgE ‐binding activities that are affected by fatty acid binding
Allergy, Volume 0, Issue ja, -Not available-. (Source: Allergy)
Source: Allergy - November 27, 2018 Category: Allergy & Immunology Authors: Roberta Aina, Pawel Dubiela, Sabine Geiselhart, Merima Bublin, Maurizio Bruschi, Christian Radauer, Christoph Nagl, Piotr Humeniuk, Riccardo Asero, Charlotte Gotthard Mortz, Christine Hafner, Karin Hoffmann ‐Sommergruber, Tomasz Borowski Tags: Letter to the Editor Source Type: research

Skin disorders are prominent features in primary immunodeficiency diseases: a systematic overview of current data
In conclusion, skin disorders are prominent features in PIDs. Through clustering of PIDs per skin disorder, we provide a support tool to use in clinical practice that should raise awareness of PIDs based on presenting skin manifestations.This article is protected by copyright. All rights reserved. (Source: Allergy)
Source: Allergy - November 27, 2018 Category: Allergy & Immunology Authors: Jill de Wit, Romke J.K. Brada, Joyce van Veldhuizen, Virgil A.S.H. Dalm, Suzanne G.M.A. Pasmans Tags: Review Source Type: research

How to discontinue omalizumab in chronic spontaneous urticaria?
Allergy, Volume 0, Issue ja, -Not available-. (Source: Allergy)
Source: Allergy - November 26, 2018 Category: Allergy & Immunology Authors: Murat T ürk, Marcus Maurer, İnsu Yılmaz Tags: Letter to the Editor Source Type: research

Increased expression of L ‐plastin in nasal polyp of patients with nonsteroidal anti‐inflammatory drug exacerbated respiratory disease
ConclusionsIncreased expression of L ‐plastin by eosinophils may contribute to abnormal fibrin deposition through TF translocation to the eosinophil cell surface in NERD nasal polyp tissue, which in turn may contribute to the pathogenesis of NERD.This article is protected by copyright. All rights reserved. (Source: Allergy)
Source: Allergy - November 26, 2018 Category: Allergy & Immunology Authors: Tetsuji Takabayashi, Yukie Tanaka, Dai Susuki, Kanako Yoshida, Kaori Tomita, Masafumi Sakashita, Yoshimasa Imoto, Yukinori Kato, Norihiko Narita, Tsugihisa Nakayama, Shinichi Haruna, Robert P. Schleimer, Shigeharu Fujieda Tags: Original Article: Airway Diseases Source Type: research

All items of the Food Allergy Quality of Life Questionnaires are relevant for peanut ‐allergic patients
Allergy, Volume 0, Issue ja, -Not available-. (Source: Allergy)
Source: Allergy - November 26, 2018 Category: Allergy & Immunology Authors: Jantina L. van der Velde, Anthony E.J. Dubois, Bertine .M.J. Flokstra – de Blok Tags: Letter to the Editor Source Type: research

RNA is taking its Toll – Impact of RNA‐specific Toll‐like receptors on health and disease
This article is protected by copyright. All rights reserved. (Source: Allergy)
Source: Allergy - November 26, 2018 Category: Allergy & Immunology Authors: Tim Vierbuchen, Karina Stein, Holger Heine Tags: Review Source Type: research

CCR10+ ILC2s with ILC1 ‐like properties exhibit a protective function in severe allergic asthma
ConclusionsFrequencies of circulating CCR10+ ILC2s and CCL27 plasma concentrations represent candidate markers of asthma severity. The characterization of CCR10+ ILC2s in human samples and in mouse asthma models suggests that these cells downregulate allergic inflammation through IFN ‐γ production.This article is protected by copyright. All rights reserved. (Source: Allergy)
Source: Allergy - November 26, 2018 Category: Allergy & Immunology Authors: Chlo é Beuraud, Vincent Lombardi, Sonia Luce, Stéphane Horiot, Emmanuel Naline, Catherine Neukirch, Sabi Airouche, Thibaut Perchet, Rachel Golub, Philippe Devillier, Sylvie Chollet‐Martin, Véronique Baron‐Bodo, Emmanuel Nony, Michel Au Tags: Original Article: Experimental Allergy and Immunology Source Type: research

Active vaccination against interleukin ‐5 as long‐term treatment for insect‐bite hypersensitivity in horses
ConclusionYearly vaccination against IL ‐5 may be a long‐term solution for the treatment of IBH and other eosinophil‐mediated diseases in horses and other species including humans. (Source: Allergy)
Source: Allergy - November 25, 2018 Category: Allergy & Immunology Authors: Antonia Fettelschoss ‐Gabriel, Victoria Fettelschoss, Florian Olomski, Katharina Birkmann, Franziska Thoms, Maya Bühler, Martin Kummer, Andris Zeltins, Thomas M. Kündig, Martin F. Bachmann Tags: ORIGINAL ARTICLE Source Type: research

Association between asthma, rhinitis and conjunctivitis multimorbidities with molecular IgE sensitization in adults
Allergy, Volume 0, Issue ja, -Not available-. (Source: Allergy)
Source: Allergy - November 25, 2018 Category: Allergy & Immunology Authors: Val érie Siroux, Anne Boudier, Rachel Nadif, Christian Lupinek, Rudolph Valenta, Jean Bousquet Tags: Letter to the Editor Source Type: research

A birch sublingual allergy immunotherapy tablet reduces rhinoconjunctivitis symptoms when exposed to birch and oak and induces IgG4 to allergens from all trees in the birch homologous group
ConclusionThis trial demonstrates that the SQ tree SLIT ‐tablet reduce ARC symptoms triggered by birch or oak pollen. The optimal dose for further development was 12 DU. Clinical and immunological findings suggest that the tablet may be used to treat allergies to all species within the birch homologous group. (Source: Allergy)
Source: Allergy - November 22, 2018 Category: Allergy & Immunology Authors: Peter Couroux, Henrik Ipsen, Brian Sonne Stage, Jakob Thomas Damkj ær, Maria Abildgaard Steffensen, Anne Marie Salapatek, Kaare Lund, Peter Adler Würtzen Tags: ORIGINAL ARTICLE Source Type: research

Tape ‐stripping alters the microbe‐host correlations in mouse skin
Allergy, EarlyView. (Source: Allergy)
Source: Allergy - November 22, 2018 Category: Allergy & Immunology Authors: Piia Karisola, Alina Suomalainen, Vittorio Fortino, Noora Ottman, Johanna Vendelin, Henrik J. Wolff, Lasse Ruokolainen, Dario Greco, Nanna Fyhrquist, Harri Alenius Tags: LETTER TO THE EDITOR Source Type: research

Breathing pattern disorder in difficult asthma: Characteristics and improvement in asthma control and quality of life after breathing re ‐training
Allergy, EarlyView. (Source: Allergy)
Source: Allergy - November 22, 2018 Category: Allergy & Immunology Authors: Eve Denton, Janet Bondarenko, Robyn E. O'Hehir, Mark Hew Tags: LETTER TO THE EDITOR Source Type: research

RAGE ‐dependent VCAM‐1 expression in the lung endothelium mediates IL‐33‐induced allergic airway inflammation
ConclusionThis study demonstrates that allergen ‐ and cytokine‐induced VCAM‐1 expression is RAGE‐dependent and contributes to lung ILC2 accumulation and downstream eosinophilic inflammation, mucus metaplasia, and type 2 inflammatory responses. (Source: Allergy)
Source: Allergy - November 22, 2018 Category: Allergy & Immunology Authors: T. N. Perkins, E. A. Oczypok, P. S. Milutinovic, R. E. Dutz, T. D. Oury Tags: ORIGINAL ARTICLE Source Type: research