Preoperative handgrip strength can predict early postoperative shoulder function in patients undergoing arthroscopic rotator cuff repair
CONCLUSIONS: Higher baseline grip strength predicts more favorable postoperative shoulder function following ARCR. A preoperative grip strength test in orthopedic clinics may serve as a predictor for postoperative shoulder functional recovery in patients undergoing ARCR.PMID:38689328 | DOI:10.1186/s13018-024-04750-8 (Source: Hand Surgery)
Source: Hand Surgery - April 30, 2024 Category: Surgery Authors: Yu-Cheng Liu Shu-Wei Huang Christopher R Adams Chung-Ying Lin Yu-Pin Chen Yi-Jie Kuo Tai-Yuan Chuang Source Type: research
The Impact of Target Vessel Anatomy and Bridging Stent Geometry on Branched Endovascular Aortic Repair Outcomes
CONCLUSION: Target vessel diameter, bridging length (gap), and horizontal misalignment seemed to be associated with adverse target vessel outcomes. This may be solved with more customised endograft solutions to reduce the negative impact of the latter parameter.PMID:38685310 | DOI:10.1016/j.ejvs.2024.04.028 (Source: PubMed: Eur J Vasc Endovasc ...)
Source: PubMed: Eur J Vasc Endovasc ... - April 30, 2024 Category: Surgery Authors: Daniel Becker Laura Sikman Ahmed Ali Carlota F Prendes Jan Stana Nikolaos Tsilimparis Source Type: research
Interposition of acellular amniotic membrane at the tendon to bone interface would be better for healing than overlaying above the tendon to bone junction in the repair of rotator cuff injury
CONCLUSION: In the RC repair model, AAM enhanced regeneration of the tendon to bone junction. This regeneration was more effective when the AAM was intervened at the tendon to bone interface than overlaid above the tendon to bone junction.PMID:38688817 | DOI:10.1016/j.cjtee.2024.04.001 (Source: Chinese Journal of Traumatology)
Source: Chinese Journal of Traumatology - April 30, 2024 Category: Orthopaedics Authors: Jiang-Tao Wang Chun-Bao Li Jia-Ting Zhang Ming-Yang An Gang Zhao Yu-Jie Liu Source Type: research
The effect of traction force on eyelid blood perfusion during closure of defects
CONCLUSIONS: Eyelid tissue seems to respond to traction in a non-linear fashion, where the initial force results in the greatest eyelid stretching and reduction in blood perfusion. The results provide information on the effects of a large force for direct closure of large eyelid defects. Considering how quickly perfusion approaches zero, the high success rate of eyelid reconstruction surgery is likely a testament to the extensive vascularization of the periocular region.PMID:38687914 | DOI:10.1080/01676830.2024.2335999 (Source: Orbit)
Source: Orbit - April 30, 2024 Category: Opthalmology Authors: Jens N ääv Ottosson Johanna V Berggren Kajsa Tenland Elin Bohman Rafi Sheikh Malin Malmsj ö Aboma Merdasa Source Type: research
Meta-analysis of the Efficacy of Photodynamic Therapy (PDT) in the Treatment of Peri-implantitis
CONCLUSION: Compared to other non-surgical treatments, PDT treatment has significant advantages in reducing peri-implant probing depth and bleeding in patients with peri-implantitis. These results suggest that PDT may be a more effective non-surgical option for reducing probing depth and bleeding in patients with peri-implantitis. Of course, future studies with larger sample sizes and longer follow-up periods are needed to confirm these findings.PMID:38687855 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - April 30, 2024 Category: Complementary Medicine Authors: Shuangxi Liu Binping Wang Zhuogeng Chen Hui Mo Min Lin Xieshan Huang Source Type: research
Atherosclerosis Is a Smooth Muscle Cell-Driven Tumor-Like Disease
CONCLUSIONS: Our findings demonstrate that atherosclerosis is an SMC-driven tumor-like disease, advancing our understanding of its pathogenesis and opening prospects for innovative precision molecular strategies aimed at preventing and treating atherosclerotic cardiovascular disease.PMID:38686559 | DOI:10.1161/CIRCULATIONAHA.123.067587 (Source: Atherosclerosis)
Source: Atherosclerosis - April 30, 2024 Category: Cardiology Authors: Huize Pan Sebastian E Ho Chenyi Xue Jian Cui Quinian S Johanson Nadja Sachs Leila S Ross Fang Li Robert A Solomon E Sander Connolly Virendra I Patel Lars Maegdefessel Hanrui Zhang Muredach P Reilly Source Type: research
Atherosclerosis Is a Smooth Muscle Cell-Driven Tumor-Like Disease
CONCLUSIONS: Our findings demonstrate that atherosclerosis is an SMC-driven tumor-like disease, advancing our understanding of its pathogenesis and opening prospects for innovative precision molecular strategies aimed at preventing and treating atherosclerotic cardiovascular disease.PMID:38686559 | DOI:10.1161/CIRCULATIONAHA.123.067587 (Source: Circulation)
Source: Circulation - April 30, 2024 Category: Cardiology Authors: Huize Pan Sebastian E Ho Chenyi Xue Jian Cui Quinian S Johanson Nadja Sachs Leila S Ross Fang Li Robert A Solomon E Sander Connolly Virendra I Patel Lars Maegdefessel Hanrui Zhang Muredach P Reilly Source Type: research
H2AX: A key player in DNA damage response and a promising target for cancer therapy
Biomed Pharmacother. 2024 Apr 29;175:116663. doi: 10.1016/j.biopha.2024.116663. Online ahead of print.ABSTRACTCancer is caused by a complex interaction of factors that interrupt the normal growth and division of cells. At the center of this process is the intricate relationship between DNA damage and the cellular mechanisms responsible for maintaining genomic stability. When DNA damage is not repaired, it can cause genetic mutations that contribute to the initiation and progression of cancer. On the other hand, the DNA damage response system, which involves the phosphorylation of the histone variant H2AX (γH2AX), is cruci...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - April 30, 2024 Category: Drugs & Pharmacology Authors: Kirti S Prabhu Shilpa Kuttikrishnan Nuha Ahamad Ummu Habeeba Zahwa Mariyam Muhammad Suleman Ajaz A Bhat Shahab Uddin Source Type: research
Periodontal granulation tissue - To remove or not to remove, that is the question
J Periodontal Res. 2024 Apr 30. doi: 10.1111/jre.13261. Online ahead of print.ABSTRACTFormation of granulation tissue is a fundamental phase in periodontal wound healing with subsequent maturation leading to regeneration or repair. However, persistently inflamed granulation tissue presents in osseous defects as a result of periodontitis and is routinely disrupted and discarded with non-surgical and surgical therapy to facilitate wound healing or improve chances of regeneration. Histological assessment suggests that granulation tissue from periodontitis-affected sites is effectively a chronic inflammatory tissue resulting f...
Source: Cell Research - April 30, 2024 Category: Cytology Authors: Ye Han Sam Luigi Nibali Mandeep Ghuman Source Type: research
The role of innate lymphoid cells in systemic lupus erythematosus
Cytokine. 2024 Apr 28;179:156623. doi: 10.1016/j.cyto.2024.156623. Online ahead of print.ABSTRACTSystemic lupus erythematosus (SLE) is a connective tissue disorder that affects various body systems. Both the innate and adaptive immunity contribute to the onset and progression of SLE. The main mechanism of SLE is an excessive immune response of immune cells to autoantigens, which leads to systemic inflammation and inflammation-induced organ damage. Notably, a subset of innate immune cells known as innate lymphoid cells (ILCs) has recently emerged. ILCs are pivotal in the early stages of infection; participate in immune resp...
Source: Cytokine - April 30, 2024 Category: Molecular Biology Authors: Yong Chen Xiaotian Gu Kunyu Cao Miao Tu Wan Liu Jiyu Ju Source Type: research
Fabrication of MXene-Based Shape Memory Hydrogel and Its Application in Skin Wound Repair
Soft Matter, 2024, Accepted Manuscript DOI: 10.1039/D4SM00157E, PaperJingchuan Hu, Jun Xie, Tao Peng, Qingwen Shi, Chen Pan, Haiying Tan, Jiuxiao Sun Wound dressings can generally finish hemostasis and provide temporary protection after skin damage. Herein, MXene-based hydrogel was prepared from MXene, gelatin, poly(ethylene glycol) diacrylate (PEGDA) and N,N'-Methylenebis(acrylamide) (HEAA) to prepare... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Soft Matter latest articles)
Source: RSC - Soft Matter latest articles - April 30, 2024 Category: Chemistry Authors: Jingchuan Hu Source Type: research
Challenging repair of the left subclavian vein in a pediatric patient
AbstractThis is a case involving a 3-year-old child who presented with an iatrogenic left subclavian/innominate vein lesion, leading to severe bleeding and intravascular catheter rupture during its removal. We successfully performed a very challenging and minimally invasive repair of the vein, along with the removal of the catheter entrapped in the innominate vein. (Source: Updates in Surgery)
Source: Updates in Surgery - April 30, 2024 Category: Surgery Source Type: research
Managing ischemic and necrotic incarcerated femoral hernia contents and their risk factors
ConclusionOpen tension-free repair was the most commonly used surgical methods for emergency incarcerated femoral hernia patients. Ischemia and necrosis of hernia contents will increase bowel resection rate and prolong operation and hospital stay. Long incarceration time is an independent risk factor for ischemia and necrosis of hernia contents. (Source: Hernia)
Source: Hernia - April 30, 2024 Category: Sports Medicine Source Type: research
Efficacy and Safety of Neoadjuvant Subcutaneous Envafolimab in dMMR/MSI-H Locally Advanced Colon Cancer
ConclusionsEnvafolimab yielded promising surgical outcomes and safety in dMMR/MSI-H locally advanced colon cancer, representing a promising treatment modality for this population. (Source: Targeted Oncology)
Source: Targeted Oncology - April 30, 2024 Category: Cancer & Oncology Source Type: research
Photodynamic and nitric oxide therapy-based synergistic antimicrobial nanoplatform: an advanced root canal irrigation system for endodontic bacterial infections
The main issues faced during the treatment of apical periodontitis are the management of bacterial infection and the facilitation of the repair of alveolar bone defects to shorten disease duration. Conventiona... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - April 30, 2024 Category: Nanotechnology Authors: Youyun Zeng, Xiangyu Hu, Zhibin Cai, Dongchao Qiu, Ying Ran, Yiqin Ding, Jiayi Shi, Xiaojun Cai and Yihuai Pan Tags: Research Source Type: research
