Preparation of modified chitosan-based nano-TiO < sub > 2 < /sub > -nisin composite packaging film and preservation mechanism applied to chilled pork
Int J Biol Macromol. 2024 Apr 25:131873. doi: 10.1016/j.ijbiomac.2024.131873. Online ahead of print.ABSTRACTHere, we developed a nano-TiO2-nisin-modified chitosan composite packaging film and investigated its properties and antibacterial activity, as well as its effect on chilled pork preservation time. The results indicated that the preservation time of chilled pork coated with a nano-TiO2-nisin-modified chitosan film (including 0.7 g/L nano-TiO2, irradiated with ultraviolet light for 40 min, and dried for 6 h) followed by modified atmosphere packaging (50% CO2 + 50% N2) increased from 7 to 20 days at 4 °C. Both nano-TiO...
Source: International Journal of Biological Macromolecules - April 27, 2024 Category: Biochemistry Authors: Ruonan Yan Mingxue Liu Xiaoqun Zeng Qiwei Du Zhen Wu Yuxing Guo Maolin Tu Daodong Pan Source Type: research

Endothelial RSPO3 mediates pulmonary endothelial regeneration by LGR4-dependent activation of β-catenin and ILK signaling pathways after inflammatory vascular injury
Int J Biol Macromol. 2024 Apr 25:131805. doi: 10.1016/j.ijbiomac.2024.131805. Online ahead of print.ABSTRACTEndothelial repair is essential for restoring tissue fluid homeostasis following lung injury. R-spondin3 (RSPO3), a secreted protein mainly produced by endothelial cells (ECs), has shown its protective effect on endothelium. However, the specific mechanisms remain unknown. To explore whether and how RSPO3 regulates endothelial regeneration after inflammatory vascular injury, the role of RSPO3 in sepsis-induced pulmonary endothelial injury was investigated in EC-specific RSPO3 knockdown, inducible EC-specific RSPO3 de...
Source: International Journal of Biological Macromolecules - April 27, 2024 Category: Biochemistry Authors: Hui Zhang Di Liu Qing-Feng Xu Juan Wei Ying Zhao Dun-Feng Xu Yan Wang Yu-Jian Liu Xiao-Yan Zhu Lai Jiang Source Type: research

Exploring carrageenan: From seaweed to biomedicine-A comprehensive review
Int J Biol Macromol. 2024 Apr 25:131822. doi: 10.1016/j.ijbiomac.2024.131822. Online ahead of print.ABSTRACTBiomaterials are pivotal in the realms of tissue engineering, regenerative medicine, and drug delivery and serve as fundamental building blocks. Within this dynamic landscape, polymeric biomaterials emerge as the frontrunners, offering unparalleled versatility across physical, chemical, and biological domains. Natural polymers, in particular, captivate attention for their inherent bioactivity. Among these, carrageenan (CRG), extracted from red seaweeds, stands out as a naturally occurring polysaccharide with immense ...
Source: International Journal of Biological Macromolecules - April 27, 2024 Category: Biochemistry Authors: Itishree Jogamaya Das Trishna Bal Source Type: research

Study on the estradiol degradation gene expression and resistance mechanism of Rhodococcus R-001 under low-temperature stress
In this study, we demonstrated six E2 degradation genes in R-001 and found for the first time that E2 degradation genes have different expression characteristics at 30°C and 10°C. Linking R-001 to cold acclimation provides new insights and a mechanistic basis for the simultaneous degradation of E2 under cold stress in Rhodococcus adaptation.PMID:38677604 | DOI:10.1016/j.chemosphere.2024.142146 (Source: Chemosphere)
Source: Chemosphere - April 27, 2024 Category: Chemistry Authors: Qing Qiu Han Li Xuejian Sun Lili Zhang Kejian Tian Menghan Chang Shuaiguo Li Hongliang Huo Source Type: research

The circAno6/miR-296-3p/TLR4 signaling axis mediates the inflammatory response to induce the activation of hepatic stellate cells
CONCLUSION: This study suggests that circAno6 and miR-296-3p/TLR4 may form a regulatory axis and regulate the inflammatory response, which in turn induces HSC activation. Targeting circAno6 may be a potential therapeutic strategy to treat LF.PMID:38677350 | DOI:10.1016/j.gene.2024.148497 (Source: Gene)
Source: Gene - April 27, 2024 Category: Genetics & Stem Cells Authors: Zhen Li Yanzhen Ma Chang Fan Hui Jiang Source Type: research

A Core Outcome Set for Intact Abdominal Aortic Aneurysm Repair
CONCLUSION: Six core outcomes are recommended for use as a minimum framework in all future studies and registries of intact open and endovascular AAA repair. Further work to select instruments for quality of life and define instruments for cognitive functioning is needed.PMID:38677466 | DOI:10.1016/j.ejvs.2024.04.029 (Source: PubMed: Eur J Vasc Endovasc ...)
Source: PubMed: Eur J Vasc Endovasc ... - April 27, 2024 Category: Surgery Authors: Matthew Machin Anders Wanhainen Mario D'Oria Mark Koelemaij Stavros Kakkos Matthew Joe Grima Janet T Powell collaborators Source Type: research

Sex Comparative Analysis on Branched and Fenestrated Endovascular Aortic Arch Repair Outcomes
CONCLUSION: Both sexes presented similar outcomes after f/b-Arch. Appropriate patient selection may decrease the effect of sex in f/b-Arch outcomes.PMID:38677467 | DOI:10.1016/j.ejvs.2024.04.030 (Source: PubMed: Eur J Vasc Endovasc ...)
Source: PubMed: Eur J Vasc Endovasc ... - April 27, 2024 Category: Surgery Authors: Petroula Nana Giuseppe Panuccio Jos é I Torrealba Fiona Rohlffs Konstantinos Spanos Tilo K ölbel Source Type: research

Combined with the first dorsal (plantar) metatarsal artery pedicle free bilobed flap with a cell scaffold for the repair of a mid-distal adjacent finger defect: a retrospective study
CONCLUSION: The surgical procedure of combined with the first dorsal (plantar) metatarsal artery pedicle free bilobed flap with a cell scaffold for the repair of mid-distal adjacent fingers defect is highly satisfactory. This approach helps the injured fingers to achieve good function, sensibility and appearance, while also achieving satisfactory results in the donor toes.PMID:38678260 | DOI:10.1186/s13018-024-04656-5 (Source: Hand Surgery)
Source: Hand Surgery - April 27, 2024 Category: Surgery Authors: Meng Ge Zhijin Zhang Guohua Ren Shenghu Hong Cheng Chen Jun Yang Qiao Hou Hongmei Fu Source Type: research

Descriptive Analysis of Outcomes After Onlay Ventral Hernia Repair in Obese Patients
CONCLUSION: Obesity is a risk factor for poor outcomes after VHR. We developed a protocol for obese patients with large defects involving a modified onlay technique which demonstrates comparable results to other VHR techniques in obese patients.PMID:38676337 | DOI:10.1177/00031348241241706 (Source: The American Surgeon)
Source: The American Surgeon - April 27, 2024 Category: Surgery Authors: Carolyn P Smullin Rivfka S Shenoy Kevin J Blair Charles F Chandler Source Type: research

Introduction to Amniotic Membranes in Maxillofacial Surgery-A Scoping Review
Conclusions: Amniotic membranes offer a versatile and effective option in maxillofacial surgery, promoting wound healing, reducing inflammation, and providing a scaffold for tissue regeneration. Further research, including randomized trials and comparative studies, is warranted to validate the efficacy and optimize the utilization of HAM in clinical practice.PMID:38674309 | PMC:PMC11051762 | DOI:10.3390/medicina60040663 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - April 27, 2024 Category: Universities & Medical Training Authors: Grzegorz Dawiec Wojciech Niemczyk Rafa ł Wiench Stanis ław Niemczyk Dariusz Skaba Source Type: research

Shift from Pro- to Anti-Inflammatory Phase in Pelvic Floor Muscles at Postpartum Matches Histological Signs of Regeneration in Multiparous Rabbits
Conclusions: A shift from the pro- to anti-inflammatory phase in the bulbospongiosus and pubococcygeus muscles of multiparous rabbits matches with centralized myonuclei, suggesting the ongoing regeneration of muscles.PMID:38674321 | PMC:PMC11052351 | DOI:10.3390/medicina60040675 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - April 27, 2024 Category: Universities & Medical Training Authors: Esteban Rodr íguez-Benítez Kenia L ópez-García Nicte Xelhuantzi Dora Luz Corona-Quintanilla Francisco Castel án Margarita Mart ínez-Gómez Source Type: research

Socioeconomic and Other Risk Factors for Retear after Arthroscopic Surgery for Nontraumatic Rotator Cuff Tear
Conclusions: Age, initial tear size, and symptom duration significantly affect retear risk after arthroscopic rotator cuff repair. Occupation and type of medical insurance were also risk factors for retear. Socioeconomically vulnerable patients may be at a greater risk of retear. Proactive efforts are required to expand early access to medical care.PMID:38674286 | PMC:PMC11052191 | DOI:10.3390/medicina60040640 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - April 27, 2024 Category: Universities & Medical Training Authors: Jung Sub Lee Kuen Tak Suh Won Chul Shin Jung Yun Bae Tae Sik Goh Sung Won Jung Min-Hyeok Choi Suk-Woong Kang Source Type: research

Role of intracranial bone marrow mesenchymal stem cells in stroke recovery: A focus on post-stroke inflammation and mitochondrial transfer
Brain Res. 2024 Apr 25:148964. doi: 10.1016/j.brainres.2024.148964. Online ahead of print.ABSTRACTStem cell therapy has become a hot research topic in the medical field in recent years, with enormous potential for treating a variety of diseases. In particular, bone marrow mesenchymal stem cells (BMSCs) have wide-ranging applications in the treatment of ischemic stroke, autoimmune diseases, tissue repair, and difficult-to-treat diseases. BMSCs can differentiate into multiple cell types and exhibit strong immunomodulatory properties. Although BMSCs can regulate the inflammatory response activated after stroke, the mechanism ...
Source: Brain Research - April 27, 2024 Category: Neurology Authors: Jiang Ming Yidong Liao Wenxue Song Zili Wang Junshuan Cui Longcai He Guangtang Chen Kaya Xu Source Type: research

Enteral plasma supports brain repair in newborn pigs after birth asphyxia
We present a new clinically relevant animal model of moderate birth asphyxia inducing structural and functional brain damage. The components in plasma that support brain repair remain to be identified but may represent a therapeutic potential for infants and animals after birth asphyxia.PMID:38677626 | DOI:10.1016/j.bbi.2024.04.032 (Source: Brain, Behavior, and Immunity)
Source: Brain, Behavior, and Immunity - April 27, 2024 Category: Neurology Authors: Gemma Chavarria Ventura Nadiya Dyshliuk Oksana Dmytriyeva Mads Jacob Bagi Nordsten Maria Mathilde Haugaard Line Iadsatian Christiansen Thomas Thymann Per Torp Sangild Stanislava Pankratova Source Type: research

Lung fibroblast-derived extracellular vesicles and soluble factors alleviate elastase-induced lung injury
In conclusion, this study highlights the therapeutic potential of both lung fibroblast-derived EV- and SF-enriched concentrates for the treatment of lung injury and emphysema.PMID:38677537 | DOI:10.1016/j.ejphar.2024.176612 (Source: European Journal of Pharmacology)
Source: European Journal of Pharmacology - April 27, 2024 Category: Drugs & Pharmacology Authors: Luke van der Koog Myrthe J Boerrigter Iris C Gorter Reinoud Gosens Anika Nagelkerke Source Type: research