Nano-copper enhanced flexible device for simultaneous measurement of human respiratory and electro-cardiac activities
Dysfunction of human respiratory and electro-cardiac activities could affect the ability of the heart to pump blood and the lungs to inhale oxygen. Thus, a device could simultaneously measure electro-cardiac s... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - May 29, 2020 Category: Nanotechnology Authors: Li Wang, Feng Zhang, Kechao Lu, Mohammed Abdulaziz, Chao Li, Chongyu Zhang, Jun Chen and Yunlun Li Tags: Research Source Type: research

Flexible liposomal gel dual-loaded with all-trans retinoic acid and betamethasone for enhanced therapeutic efficiency of psoriasis
Psoriasis is a chronic immune-mediated inflammatory skin disease without effective treatment. The utilization of all trans-retinoic acid (TRA) and betamethasone (BT) for the treatment of psoriasis is still fac... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - May 24, 2020 Category: Nanotechnology Authors: Wei Wang, Gao-feng Shu, Kong-jun Lu, Xiao-ling Xu, Min-cheng Sun, Jing Qi, Qiao-ling Huang, Wei-qiang Tan and Yong-zhong Du Tags: Research Source Type: research

Real-time monitoring of bacterial biofilms metabolic activity by a redox-reactive nanosensors array
Bacterial biofilms are communities of surface-associated microorganisms living in cellular clusters or micro-colonies, encapsulated in a complex matrix composed of an extracellular polymeric substance, separat... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - May 24, 2020 Category: Nanotechnology Authors: Ella Yeor-Davidi, Marina Zverzhinetsky, Vadim Krivitsky and Fernando Patolsky Tags: Research Source Type: research

p62/SQSTM1 accumulation due to degradation inhibition and transcriptional activation plays a critical role in silica nanoparticle-induced airway inflammation via NF- κB activation
Most nanoparticles (NPs) reportedly block autophagic flux, thereby upregulating p62/SQSTM1 through degradation inhibition. p62 also acts as a multifunctional scaffold protein with multiple domains, and is invo... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - May 19, 2020 Category: Nanotechnology Authors: Yifan Wu, Yang Jin, Tianyu Sun, Piaoyu Zhu, Jinlong Li, Qinglin Zhang, Xiaoke Wang, Junkang Jiang, Gang Chen and Xinyuan Zhao Tags: Research Source Type: research

Correction to: Astaxanthin-loaded polymer-lipid hybrid nanoparticles (ATX-LPN): assessment of potential otoprotective effects
An amendment to this paper has been published and can be accessed via the original article. (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - May 19, 2020 Category: Nanotechnology Authors: Jiayi Gu, Yuming Chen, Ling Tong, Xueling Wang, Dehong Yu and Hao Wu Tags: Correction Source Type: research

Correction to: Iron oxides nanoparticles (IOs) exposed to magnetic field promote expression of osteogenic markers in osteoblasts through integrin alpha-3 (INTa-3) activation, inhibits osteoclasts activity and exerts anti-inflammatory action
An amendment to this paper has been published and can be accessed via the original article. (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - May 19, 2020 Category: Nanotechnology Authors: K. Marycz, P. Sobierajska, M. Roecken, K. Kornicka-Garbowska, M. K ępska, R. Idczak, J.-M. Nedelec and R. J. Wiglusz Tags: Correction Source Type: research

Graphene oxide nanofilm and the addition of l-glutamine can promote development of embryonic muscle cells
Formation of muscular pseudo-tissue depends on muscle precursor cells, the extracellular matrix (ECM)-mimicking structure and factors stimulating cell differentiation. These three things cooperate and can crea... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - May 15, 2020 Category: Nanotechnology Authors: Marlena Zieli ńska-Górska, Anna Hotowy, Mateusz Wierzbicki, Jaśmina Bałaban, Malwina Sosnowska, Sławomir Jaworski, Barbara Strojny, André Chwalibog and Ewa Sawosz Tags: Research Source Type: research

Encapsulation of the dual FLAP/mPEGS-1 inhibitor BRP-187 into acetalated dextran and PLGA nanoparticles improves its cellular bioactivity
Dual inhibitors of the 5-lipoxygenase-activating protein (FLAP) and the microsomal prostaglandin E2 synthase-1 (mPGES-1) may exert better anti-inflammatory efficacy and lower risks of adverse effects versus non-s... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - May 14, 2020 Category: Nanotechnology Authors: Blerina Shkodra-Pula, Christian Kretzer, Paul M. Jordan, Paul Klemm, Andreas Koeberle, David Pretzel, Erden Banoglu, Stefan Lorkowski, Maria Wallert, Stephanie H öppener, Steffi Stumpf, Antje Vollrath, Stephanie Schubert, Oliver Werz and Ulrich S. Schube Tags: Research Source Type: research

Facile synthesis and nanoscale features of a nanostructured nordihydroguaiaretic acid analog for therapeutic applications
Nordihydroguaiaretic acid (NDGA) is a plant lignan obtained from creosote bush, known to possess anti-oxidant, anti-cancer and anti-viral activities and is being used in traditional medicine. However, toxicity... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - May 14, 2020 Category: Nanotechnology Authors: Geraldine Sandana Mala John, Veena Kumari Vuttaradhi, Satoru Takeuchi, Ravi Shankar Pitani, Ganesh Venkatraman and Suresh Kumar Rayala Tags: Research Source Type: research

Engineering nanoparticles to reprogram radiotherapy and immunotherapy: recent advances and future challenges
Nanoparticles (NPs) have been increasingly studied for radiosensitization. The principle of NPs radio-enhancement is to use high-atomic number NPs (e.g. gold, hafnium, bismuth and gadolinium) or deliver radios... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - May 14, 2020 Category: Nanotechnology Authors: Jing Jin and Qijie Zhao Tags: Review Source Type: research

Neuron tau-targeting biomimetic nanoparticles for curcumin delivery to delay progression of Alzheimer ’s disease
Although many therapeutic strategies for Alzheimer ’s disease (AD) have been explored, these strategies are seldom used in the clinic. Therefore, AD therapeutic research is still urgently needed. One major chal... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - May 13, 2020 Category: Nanotechnology Authors: Chunhong Gao, Xiaoyang Chu, Wei Gong, Jinpeng Zheng, Xiangyang Xie, Yuli Wang, Meiyan Yang, Zhiping Li, Chunsheng Gao and Yang Yang Tags: Research Source Type: research

MicroRNA-421-3p-abundant small extracellular vesicles derived from M2 bone marrow-derived macrophages attenuate apoptosis and promote motor function recovery via inhibition of mTOR in spinal cord injury
Spinal cord injury (SCI) has a very disabling central nervous system impact but currently lacks effective treatment. Bone marrow-derived macrophages (BMDMs) are recruited to the injured area after SCI and part... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - May 13, 2020 Category: Nanotechnology Authors: Jiaxing Wang, Yuluo Rong, Chengyue Ji, Chengtang Lv, Dongdong Jiang, Xuhui Ge, Fangyi Gong, Pengyu Tang, Weihua Cai, Wei Liu and Jin Fan Tags: Research Source Type: research

Negative depletion mediated brightfield circulating tumour cell identification strategy on microparticle-based microfluidic chip
The most convenient circulating tumor cells (CTCs) identification method is direct analysis of cells under bright field microscopy by which CTCs can be comprehensive studied based on morphology, phenotype or e... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - May 7, 2020 Category: Nanotechnology Authors: Shuibing Wang, Shaoli Hong, Shijia Cai, Jia Lei, Jinyao Chen, Nangang Zhang, Zhao Ai, Kan Liu and Man Tang Tags: Research Source Type: research

Saliva exosomes-derived UBE2O mRNA promotes angiogenesis in cutaneous wounds by targeting SMAD6
Enhancing angiogenesis is critical for accelerating wound healing. Application of different types of exosomes (Exos) to promote angiogenesis represents a novel strategy for enhanced wound repair. Saliva is kno... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - May 6, 2020 Category: Nanotechnology Authors: Bobin Mi, Lang Chen, Yuan Xiong, Chenchen Yan, Hang Xue, Adriana C. Panayi, Jing Liu, Liangcong Hu, Yiqiang Hu, Faqi Cao, Yun Sun, Wu Zhou and Guohui Liu Tags: Research Source Type: research

Isolated cell-bound membrane vesicles (CBMVs) as a novel class of drug nanocarriers
Cell-bound membrane vesicles (CBMVs) are a type of membrane vesicles different from the well-known extracellular vesicles (EVs). In recent years, the applications of EVs as drug delivery systems have been stud... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - May 6, 2020 Category: Nanotechnology Authors: Yang Zhang, Yang Liu, Wendiao Zhang, Qisheng Tang, Yun Zhou, Yuanfang Li, Tong Rong, Huaying Wang and Yong Chen Tags: Research Source Type: research

Treatment of breast cancer with autophagy inhibitory microRNAs carried by AGO2-conjugated nanoparticles
Nanoparticle based gene delivery systems holds great promise. Superparamagnetic iron oxide nanoparticles (SPIONs) are being heavily investigated due to good biocompatibility and added diagnostic potential, ren... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - April 28, 2020 Category: Nanotechnology Authors: Ozlem Unal, Yunus Akkoc, Muhammed Kocak, Esra Nalbat, Asiye Isin Dogan-Ekici, Havva Yagci Acar and Devrim Gozuacik Tags: Research Source Type: research

M2 Macrophagy-derived exosomal miRNA-5106 induces bone mesenchymal stem cells towards osteoblastic fate by targeting salt-inducible kinase 2 and 3
Osteoblast differentiation is a vital process for fracture healing, and exosomes are nanosized membrane vesicles that can deliver therapeutic drugs easily and safely. Macrophages participate in the regulation ... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - April 28, 2020 Category: Nanotechnology Authors: Yuan Xiong, Lang Chen, Chenchen Yan, Wu Zhou, Tao Yu, Yun Sun, Faqi Cao, Hang Xue, Yiqiang Hu, Dong Chen, Bobin Mi and Guohui Liu Tags: Research Source Type: research

Oral delivery of exenatide-loaded hybrid zein nanoparticles for stable blood glucose control and β-cell repair of type 2 diabetes mice
Exenatide is an insulinotropic peptide drug for type 2 diabetes treatment with low risk of hypoglycemia, and is administrated by subcutaneous injection. Oral administration is the most preferred route for life... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - April 28, 2020 Category: Nanotechnology Authors: Xiaoyan Bao, Kang Qian and Ping Yao Tags: Research Source Type: research

Growth and elongation of axons through mechanical tension mediated by fluorescent-magnetic bifunctional Fe3O4 ·Rhodamine 6G@PDA superparticles
The primary strategy to repair peripheral nerve injuries is to bridge the lesions by promoting axon regeneration. Thus, the ability to direct and manipulate neuronal cell axon regeneration has been one of the ... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - April 25, 2020 Category: Nanotechnology Authors: Yang Wang, Binxi Li, Hao Xu, Shulin Du, Ting Liu, Jingyan Ren, Jiayi Zhang, Hao Zhang, Yi Liu and Laijin Lu Tags: Research Source Type: research

Effect of the cagW-based gene vaccine on the immunologic properties of BALB/c mouse: an efficient candidate for Helicobacter pylori DNA vaccine
This study aims to design a vaccine on the basis of cagW agains... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - April 21, 2020 Category: Nanotechnology Authors: Mohammad Chehelgerdi and Abbas Doosti Tags: Research Source Type: research

Application of magnetic nanoparticles in nucleic acid detection
Nucleic acid is the main material for storing, copying, and transmitting genetic information. Gene sequencing is of great significance in DNA damage research, gene therapy, mutation analysis, bacterial infecti... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - April 21, 2020 Category: Nanotechnology Authors: Congli Tang, Ziyu He, Hongmei Liu, Yuyue Xu, Hao Huang, Gaojian Yang, Ziqi Xiao, Song Li, Hongna Liu, Yan Deng, Zhu Chen, Hui Chen and Nongyue He Tags: Review Source Type: research

Metal ion-responsive nanocarrier derived from phosphonated calix[4]arenes for delivering dauricine specifically to sites of brain injury in a mouse model of intracerebral hemorrhage
Primary intracerebral hemorrhage (ICH) is a leading cause of long-term disability and death worldwide. Drug delivery vehicles to treat ICH are less than satisfactory because of their short circulation lives, l... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - April 19, 2020 Category: Nanotechnology Authors: Mingxin Li, Guohao Liu, Kaixuan Wang, Lingfeng Wang, Xiang Fu, Lee Yong Lim, Wei Chen and Jingxin Mo Tags: Research Source Type: research

Homotypic cell membrane-cloaked biomimetic nanocarrier for the accurate photothermal-chemotherapy treatment of recurrent hepatocellular carcinoma
Tumor recurrence in patients after surgery severely reduces the survival rate of surgical patients. Targeting and killing recurrent tumor cells and tissues is extremely important for the cancer treatment. (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - April 16, 2020 Category: Nanotechnology Authors: Yingxue Sun, Wenhui Zhai, Xiaojun Liu, Xiangyi Song, Xiaonan Gao, Kehua Xu and Bo Tang Tags: Research Source Type: research

A multifunctional platform with single-NIR-laser-triggered photothermal and NO release for synergistic therapy against multidrug-resistant Gram-negative bacteria and their biofilms
Infectious diseases caused by multidrug-resistant (MDR) bacteria, especially MDR Gram-negative strains, have become a global public health challenge. Multifunctional nanomaterials for controlling MDR bacterial... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - April 15, 2020 Category: Nanotechnology Authors: Baohua Zhao, He Wang, Wenjing Dong, Shaowen Cheng, Haisheng Li, Jianglin Tan, Junyi Zhou, Weifeng He, Lanlan Li, Jianxiang Zhang, Gaoxing Luo and Wei Qian Tags: Research Source Type: research

Lipoplex-based targeted gene therapy for the suppression of tumours with VEGFR expression by producing anti-angiogenic molecules
The anti-angiogenic fusion protein RBDV-IgG1 Fc (RBDV), which comprises the receptor-binding domain of vascular endothelial growth factor-A (VEGF-A), has shown antitumour effects by reducing angiogenesis in vi... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - April 9, 2020 Category: Nanotechnology Authors: Shu-Yi Ho, Pin-Rong Chen, Chia-Hung Chen, Nu-Man Tsai, Yu-Hsin Lin, Chen-Si Lin, Cheng-Hsun Chuang, Xiao-Fan Huang, Yi-Lin Chan, Yen-Ku Liu, Chen-Han Chung, Shun-Long Weng and Kuang-Wen Liao Tags: Research Source Type: research

Preparation, characterization and in vitro –in vivo evaluation of bortezomib supermolecular aggregation nanovehicles
Intolerable toxicity and unsatisfactory therapeutic effects are still big problems retarding the use of chemotherapy against cancer. Nano-drug delivery system promised a lot in increasing the patients ’ complia... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - April 3, 2020 Category: Nanotechnology Authors: Ming-yue Chen, Ze-kuan Xiao, Xue-ping Lei, Jie-xia Li, Xi-yong Yu, Jian-ye Zhang, Guo-dong Ye, Yu-juan Guo, Guangquan Mo, Chu-wen Li, Yu Zhang, Ling-min Zhang, Zhi-qiang Lin and Ji-jun Fu Tags: Research Source Type: research

Development of erianin-loaded dendritic mesoporous silica nanospheres with pro-apoptotic effects and enhanced topical delivery
Psoriasis is a malignant skin disease characterized as keratinocyte hyperproliferation and aberrant differentiation. Our previous work reported that a bibenzyl compound, erianin, has a potent inhibitory effect... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - March 30, 2020 Category: Nanotechnology Authors: Canlong Mo, Lulu Lu, Danyang Liu and Kun Wei Tags: Research Source Type: research

Drug affinity and targeted delivery: double functionalization of silk spheres for controlled doxorubicin delivery into Her2-positive cancer cells
The optimal drug delivery system should be biocompatible, biodegradable, and allow the sustained release of the drug only after it reaches the target cells. Silk, as a natural polymer, is a great candidate for... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - March 30, 2020 Category: Nanotechnology Authors: Kamil Kucharczyk, Anna Florczak, Tomasz Deptuch, Karolina Penderecka, Katarzyna Jastrzebska, Andrzej Mackiewicz and Hanna Dams-Kozlowska Tags: Research Source Type: research

Porous gold nanoparticles for attenuating infectivity of influenza A virus
Influenza viruses (IVs) have become increasingly resistant to antiviral drugs that target neuraminidase and matrix protein 2 due to gene mutations that alter their drug-binding target protein regions. Conseque... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - March 24, 2020 Category: Nanotechnology Authors: Jinyoung Kim, Minjoo Yeom, Taeksu Lee, Hyun-Ouk Kim, Woonsung Na, Aram Kang, Jong-Woo Lim, Geunseon Park, Chaewon Park, Daesub Song and Seungjoo Haam Tags: Research Source Type: research

Astaxanthin-loaded polymer-lipid hybrid nanoparticles (ATX-LPN): assessment of potential otoprotective effects
Ototoxicity is one of the major side effects of platinum-based chemotherapy, especially cisplatin therapy. To date, no FDA approved agents to alleviate or prevent this ototoxicity are available. However, ototo... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - March 19, 2020 Category: Nanotechnology Authors: Jiayi Gu, Yuming Chen, Ling Tong, Xueling Wang, Dehong Yu and Hao Wu Tags: Research Source Type: research

Intravenous delivery of enzalutamide based on high drug loading multifunctional graphene oxide nanoparticles for castration-resistant prostate cancer therapy
Enzalutamide (Enz) has shown limited bioavailability via oral administration. Castration-resistant prostate cancer (CRPC) is frequent among patients receiving 18 –24 months of androgen deprivation therapy. The ... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - March 18, 2020 Category: Nanotechnology Authors: Wenjun Jiang, Jiyuan Chen, Chunai Gong, Yuanyuan Wang, Yuan Gao and Yongfang Yuan Tags: Research Source Type: research

Nylon-6/chitosan core/shell antimicrobial nanofibers for the prevention of mesh-associated surgical site infection
The state-of-the-art hernia meshes, used in hospitals for hernia repair, are predominantly polymeric textile-based constructs that present high mechanical strength, but lack antimicrobial properties. Consequen... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - March 18, 2020 Category: Nanotechnology Authors: Antonios Keirouz, Norbert Radacsi, Qun Ren, Alex Dommann, Guido Beldi, Katharina Maniura-Weber, Ren é M. Rossi and Giuseppino Fortunato Tags: Research Source Type: research

The interrupted effect of autophagic flux and lysosomal function induced by graphene oxide in p62-dependent apoptosis of F98 cells
Graphene oxide (GO) nanoparticles (NPs) have been widely applied in various fields, especially in biomedical applications. Extensive studies have suggested that GO can pass through the blood –brain barrier (BBB... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - March 18, 2020 Category: Nanotechnology Authors: Chao Zhang, Xiaoli Feng, Longwen He, Yaqing Zhang and Longquan Shao Tags: Research Source Type: research

Matrix metalloprotein-triggered, cell penetrating peptide-modified star-shaped nanoparticles for tumor targeting and cancer therapy
Specific targeting ability and good cell penetration are two critical requirements of tumor-targeted delivery systems. In the present work, we developed a novel matrix metalloprotein-triggered, cell-penetratin... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - March 17, 2020 Category: Nanotechnology Authors: Fangyuan Guo, Qiafan Fu, Kang Zhou, Chenghao Jin, Wenchao Wu, Xugang Ji, Qinying Yan, Qingliang Yang, Danjun Wu, Aiqin Li and Gensheng Yang Tags: Research Source Type: research

Rationally assembled albumin/indocyanine green nanocomplex for enhanced tumor imaging to guide photothermal therapy
Herein, a novel phototheranostic nanocomplex that is self-assembled from bovine serum albumin (BSA) and indocyanine green (ICG) is developed for enhanced near-infrared (NIR) fluorescence imaging, which benefit... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - March 17, 2020 Category: Nanotechnology Authors: Feifei An, Zhao Yang, Meichen Zheng, Ting Mei, Guowei Deng, Ping Guo, Yanan Li and Ruilong Sheng Tags: Research Source Type: research

Exosomal miRNA-128-3p from mesenchymal stem cells of aged rats regulates osteogenesis and bone fracture healing by targeting Smad5
Transplantation of mesenchymal stem cells (MSCs) has been considered an effective therapeutic treatment for a variety of diseases including bone fracture. However, there are associated complications along with... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - March 16, 2020 Category: Nanotechnology Authors: Tao Xu, Yongjun Luo, Jiaxing Wang, Ning Zhang, Changjiang Gu, Linwei Li, Dingfei Qian, Weihua Cai, Jin Fan and Guoyong Yin Tags: Research Source Type: research

Fenobody and RANbody-based sandwich enzyme-linked immunosorbent assay to detect Newcastle disease virus
Traditional sandwich enzyme-linked immunosorbent assay (ELISA) using polyclonal and monoclonal antibodies as reagents presents several drawbacks, including limited amounts, difficulty in permanent storage, and... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - March 14, 2020 Category: Nanotechnology Authors: Pinpin Ji, Jiahong Zhu, Xiaoxuan Li, Wenqi Fan, Qianqian Liu, Kun Wang, Jiakai Zhao, Yani Sun, Baoyuan Liu, En-Min Zhou and Qin Zhao Tags: Research Source Type: research

Surface chemistry governs the sub-organ transfer, clearance and toxicity of functional gold nanoparticles in the liver and kidney
To effectively applied nanomaterials (NMs) in medicine, one of the top priorities is to address a better understanding of the possible sub-organ transfer, clearance routes, and potential toxicity of the NMs in... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - March 14, 2020 Category: Nanotechnology Authors: Xue Li, Bing Wang, Shuang Zhou, Wei Chen, Hanqing Chen, Shanshan Liang, Lingna Zheng, Hongyang Yu, Runxuan Chu, Meng Wang, Zhifang Chai and Weiyue Feng Tags: Research Source Type: research

Enhancement of sciatic nerve regeneration with dual delivery of vascular endothelial growth factor and nerve growth factor genes
Peripheral nerve injury is one common clinical disease worldwide, in which sciatic nerve is anatomically the most challenging to regenerate given its length and large cross-sectional area. For the present, aut... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - March 14, 2020 Category: Nanotechnology Authors: Zhiwei Fang, Xuemei Ge, Xuan Chen, Yang Xu, Wei-En Yuan and Yuanming Ouyang Tags: Research Source Type: research

Magnetic core –shell nanowires as MRI contrast agents for cell tracking
Identifying the precise location of cells and their migration dynamics is of utmost importance for achieving the therapeutic potential of cells after implantation into a host. Magnetic resonance imaging is a s... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - March 12, 2020 Category: Nanotechnology Authors: Aldo Isaac Mart ínez-Banderas, Antonio Aires, Sandra Plaza-García, Lorena Colás, Julián A. Moreno, Timothy Ravasi, Jasmeen S. Merzaban, Pedro Ramos-Cabrer, Aitziber L. Cortajarena and Jürgen Kosel Tags: Research Source Type: research

Docetaxel-loaded solid lipid nanoparticles prevent tumor growth and lung metastasis of 4T1 murine mammary carcinoma cells
Metastasis causes the most breast cancer-related deaths in women. Here, we investigated the antitumor effect of solid lipid nanoparticles (SLN-DTX) when used in the treatment of metastatic breast tumors using ... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - March 12, 2020 Category: Nanotechnology Authors: M árcia Cristina Oliveira da Rocha, Patrícia Bento da Silva, Marina Arantes Radicchi, Bárbara Yasmin Garcia Andrade, Jaqueline Vaz de Oliveira, Tom Venus, Carolin Merker, Irina Estrela-Lopis, João Paulo Figueiró Longo and Sônia Nair Báo Tags: Research Source Type: research

Surface chemistry modified upconversion nanoparticles as fluorescent sensor array for discrimination of foodborne pathogenic bacteria
The identification of foodborne pathogenic bacteria types plays a crucial role in food safety and public health. In consideration of long culturing times, tedious operations and the desired specific recognitio... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - February 28, 2020 Category: Nanotechnology Authors: Mingyuan Yin, Chuang Jing, Haijie Li, Qiliang Deng and Shuo Wang Tags: Research Source Type: research

Preparation of antibacterial and osteoconductive 3D-printed PLGA/Cu(I)@ZIF-8 nanocomposite scaffolds for infected bone repair
In this study, copper-loaded-ZIF-8 nanoparticles and poly (lactide-co-glycolide) (PLGA) were combined to fabricate porous PLGA/Cu(I)@ZIF... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - February 27, 2020 Category: Nanotechnology Authors: Fei Zou, Jianyuan Jiang, Feizhou Lv, Xinlei Xia and Xiaosheng Ma Tags: Research Source Type: research

Manipulation of macrophage polarization by peptide-coated gold nanoparticles and its protective effects on acute lung injury
Macrophage polarization and reprogramming in the lung play a critical role in the initiation, development and progression of acute lung injury (ALI). Regulating the activation and differentiation of pulmonary ... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - February 26, 2020 Category: Nanotechnology Authors: Lu Wang, Huasheng Zhang, Liya Sun, Wei Gao, Ye Xiong, Aying Ma, Xiali Liu, Lei Shen, Qiang Li and Hong Yang Tags: Research Source Type: research

Genes expression profiling of alveolar macrophages exposed to non-functionalized, anionic and cationic multi-walled carbon nanotubes shows three different mechanisms of toxicity
Functionalized multi-walled carbon nanotubes (MWCNT) have become the focus of increased research interest, particularly in their application as tools in different areas, such as the biomedical field. Despite t... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - February 24, 2020 Category: Nanotechnology Authors: Sara Nahle, Hilary Cassidy, M élanie M. Leroux, Reuben Mercier, Jaafar Ghanbaja, Zahra Doumandji, David Matallanas, Bertrand H. Rihn, Olivier Joubert and Luc Ferrari Tags: Research Source Type: research

Triazine-cored polymeric vectors for antisense oligonucleotide delivery in vitro and in vivo
The polymer-based drug/gene delivery is promising for the treatment of inherent or acquire disease, because of the polymer ’s structural flexibility, larger capacity for therapeutic agent, low host immunogenici... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - February 18, 2020 Category: Nanotechnology Authors: Mingxing Wang, Bo Wu, Jason D. Tucker, Sapana N. Shah, Peijuan Lu and Qilong Lu Tags: Research Source Type: research

Antibacterial activity of iron oxide, iron nitride, and tobramycin conjugated nanoparticles against Pseudomonas aeruginosa biofilms
Novel methods are necessary to reduce morbidity and mortality of patients suffering from infections with Pseudomonas aeruginosa. Being the most common infectious species of the Pseudomonas genus, P. aeruginosa is... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - February 18, 2020 Category: Nanotechnology Authors: Leisha M. Armijo, Stephen J. Wawrzyniec, Michael Kopciuch, Yekaterina I. Brandt, Antonio C. Rivera, Nathan J. Withers, Nathaniel C. Cook, Dale L. Huber, Todd C. Monson, Hugh D. C. Smyth and Marek Osi ński Tags: Research Source Type: research

Proteome interrogation using gold nanoprobes to identify targets of arctigenin in fish parasites
Gold nanoparticles (GNPs) are one of the most widely used nanomaterials in various fields. Especially, the unique chemical and physical properties make them as the promising candidates in drug target identific... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - February 18, 2020 Category: Nanotechnology Authors: Xiao Tu, Xiaoping Tan, Xiaozhou Qi, Aiguo Huang, Fei Ling and Gaoxue Wang Tags: Research Source Type: research

Iron oxides nanoparticles (IOs) exposed to magnetic field promote expression of osteogenic markers in osteoblasts through integrin alpha-3 (INTa-3) activation, inhibits osteoclasts activity and exerts anti-inflammatory action
Prevalence of osteoporosis is rapidly growing and so searching for novel therapeutics. Yet, there is no drug on the market available to modulate osteoclasts and osteoblasts activity simultaneously. Thus in pre... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - February 18, 2020 Category: Nanotechnology Authors: K. Marycz, P. Sobierajska, M. Roecken, K. Kornicka-Garbowska, M. K ępska, R. Idczak, J.-M. Nedelec and R. J. Wiglusz Tags: Research Source Type: research

Metabolomic analyses of the bio-corona formed on TiO2 nanoparticles incubated with plant leaf tissues
The surface of a nanoparticle adsorbs molecules from its surroundings with a specific affinity determined by the chemical and physical properties of the nanomaterial. When a nanoparticle is exposed to a biolog... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - February 17, 2020 Category: Nanotechnology Authors: Jasmina Kurepa, Timothy E. Shull and Jan A. Smalle Tags: Research Source Type: research