Capsules for the Diagnosis and Treatment of Gastrointestinal Motility Disorders- A Game Changer
AbstractPurpose of ReviewOver the last few decades, there have been remarkable strides in endoscopy and radiological imaging that have advanced gastroenterology. However, the management of neurogastroenterological disorders has lagged behind, in part handicapped by the use of catheter-based manometry that is both non-physiological and uncomfortable. The advent of capsule technology has been a game changer for both diagnostic and therapeutic applications.Recent FindingsHere, we discuss several capsule devices that are available or under investigation. There are three technologies that are FDA approved. Wireless motility cap...
Source: Current Gastroenterology Reports - April 17, 2024 Category: Gastroenterology Source Type: research

The performance of artificial intelligence large language model-linked chatbots in surgical decision-making for gastroesophageal reflux disease
ConclusionsGastrointestinal surgeons, gastroenterologists, and patients should recognize both the promise and pitfalls of LLM ’s when utilized for advice on surgical management of GERD. Additional training of LLM’s using evidence-based health information is needed. (Source: Surgical Endoscopy)
Source: Surgical Endoscopy - April 17, 2024 Category: Surgery Source Type: research

Inflammatory Causes of Dysphagia in Children
Gastroesophageal reflux (GER) and eosinophilic esophagitis (EoE) are the most common inflammatory causes of pediatric dysphagia, but several other less prevalent conditions should be considered. These conditions can affect one or several aspects of the swallowing process. In some inflammatory conditions dysphagia may be an early symptom. Esophagoscopy and instrumental swallow studies are often needed to determine the underlying diagnosis and best treatment plan. In some inflammatory conditions dysphagia can portend a worse outcome and need for more aggressive treatment of the underlying condition. Consultations with speech...
Source: Otolaryngologic clinics of North America - April 17, 2024 Category: ENT & OMF Authors: Marisa A. Ryan, Anna Ermarth Source Type: research

Capsules for the Diagnosis and Treatment of Gastrointestinal Motility Disorders- A Game Changer
AbstractPurpose of ReviewOver the last few decades, there have been remarkable strides in endoscopy and radiological imaging that have advanced gastroenterology. However, the management of neurogastroenterological disorders has lagged behind, in part handicapped by the use of catheter-based manometry that is both non-physiological and uncomfortable. The advent of capsule technology has been a game changer for both diagnostic and therapeutic applications.Recent FindingsHere, we discuss several capsule devices that are available or under investigation. There are three technologies that are FDA approved. Wireless motility cap...
Source: Current Gastroenterology Reports - April 17, 2024 Category: Gastroenterology Source Type: research

Utility of proximal mean nocturnal basal impedance in gastroesophageal reflux disease —A preliminary experience
(Source: Indian Journal of Gastroenterology)
Source: Indian Journal of Gastroenterology - April 15, 2024 Category: Gastroenterology Source Type: research

Correction: Risk factors associated with functional esophageal disorders (FED) versus gastroesophageal reflux disease (GERD)
(Source: Surgical Endoscopy)
Source: Surgical Endoscopy - April 15, 2024 Category: Surgery Source Type: research

Differences Between Patients with Heartburn Refractory to Vonoprazan and Those Refractory to Proton Pump Inhibitors
ConclusionPatients with unproven GERD with vonoprazan-refractory heartburn demonstrated more symptoms, including not only GERD symptoms but also functional dyspepsia and irritable bowel syndrome symptoms, than those with PPI-refractory heartburn. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - April 15, 2024 Category: Gastroenterology Source Type: research

Utility of proximal mean nocturnal basal impedance in gastroesophageal reflux disease —A preliminary experience
(Source: Indian Journal of Gastroenterology)
Source: Indian Journal of Gastroenterology - April 15, 2024 Category: Gastroenterology Source Type: research

Proton Pump Inhibitors and Cancer Risk: A Comprehensive Review of Epidemiological and Mechanistic Evidence
Conclusions: Despite the well-established cancer risk associated with PPIs, it is notable that these medications continue to be widely prescribed for periods longer than 3 months. Thus, it is of paramount importance for clinicians and patients to thoughtfully evaluate the potential risks and benefits of long-term PPI usage and explore alternative treatments before making informed decisions regarding their medical management.PMID:38610738 | DOI:10.3390/jcm13071970 (Source: Clinical Colorectal Cancer)
Source: Clinical Colorectal Cancer - April 13, 2024 Category: Cancer & Oncology Authors: Ibrahim O Sawaid Abraham O Samson Source Type: research

Proton Pump Inhibitors and Cancer Risk: A Comprehensive Review of Epidemiological and Mechanistic Evidence
Conclusions: Despite the well-established cancer risk associated with PPIs, it is notable that these medications continue to be widely prescribed for periods longer than 3 months. Thus, it is of paramount importance for clinicians and patients to thoughtfully evaluate the potential risks and benefits of long-term PPI usage and explore alternative treatments before making informed decisions regarding their medical management.PMID:38610738 | PMC:PMC11012754 | DOI:10.3390/jcm13071970 (Source: Clinical Colorectal Cancer)
Source: Clinical Colorectal Cancer - April 13, 2024 Category: Cancer & Oncology Authors: Ibrahim O Sawaid Abraham O Samson Source Type: research

Difference of Esophageal Motility and Reflux Characteristics in Patients with Gastroesophageal Reflux Disease (GERD) and Chronic Cough (CC) and the Impact of Standardized Drug Therapy
This study aimed to explore the difference between esophageal motility and reflux characteristics in patients with gastroesophageal reflux disease (GERD) and chronic cough (CC) and the effect of standardized drug therapy. Eighty-four patients diagnosed with GERD in The First People's Hospital of Hangzhou from December 2020 to December 2022 were enrolled in this study. They were divided into an observation group (Obs group, patients with GERD + CC, n = 26 cases) and a control group (control group, patients with typical GERD, n = 58 cases). Reflux symptom integral questionnaire, cough symptom integral questionnaire, high-res...
Source: Alternative Therapies in Health and Medicine - April 12, 2024 Category: Complementary Medicine Authors: Wenfang Liu Yuqing Tong Source Type: research

Difference of Esophageal Motility and Reflux Characteristics in Patients with Gastroesophageal Reflux Disease (GERD) and Chronic Cough (CC) and the Impact of Standardized Drug Therapy
This study aimed to explore the difference between esophageal motility and reflux characteristics in patients with gastroesophageal reflux disease (GERD) and chronic cough (CC) and the effect of standardized drug therapy. Eighty-four patients diagnosed with GERD in The First People's Hospital of Hangzhou from December 2020 to December 2022 were enrolled in this study. They were divided into an observation group (Obs group, patients with GERD + CC, n = 26 cases) and a control group (control group, patients with typical GERD, n = 58 cases). Reflux symptom integral questionnaire, cough symptom integral questionnaire, high-res...
Source: Alternative Therapies in Health and Medicine - April 12, 2024 Category: Complementary Medicine Authors: Wenfang Liu Yuqing Tong Source Type: research

Difference of Esophageal Motility and Reflux Characteristics in Patients with Gastroesophageal Reflux Disease (GERD) and Chronic Cough (CC) and the Impact of Standardized Drug Therapy
This study aimed to explore the difference between esophageal motility and reflux characteristics in patients with gastroesophageal reflux disease (GERD) and chronic cough (CC) and the effect of standardized drug therapy. Eighty-four patients diagnosed with GERD in The First People's Hospital of Hangzhou from December 2020 to December 2022 were enrolled in this study. They were divided into an observation group (Obs group, patients with GERD + CC, n = 26 cases) and a control group (control group, patients with typical GERD, n = 58 cases). Reflux symptom integral questionnaire, cough symptom integral questionnaire, high-res...
Source: Alternative Therapies in Health and Medicine - April 12, 2024 Category: Complementary Medicine Authors: Wenfang Liu Yuqing Tong Source Type: research

Difference of Esophageal Motility and Reflux Characteristics in Patients with Gastroesophageal Reflux Disease (GERD) and Chronic Cough (CC) and the Impact of Standardized Drug Therapy
This study aimed to explore the difference between esophageal motility and reflux characteristics in patients with gastroesophageal reflux disease (GERD) and chronic cough (CC) and the effect of standardized drug therapy. Eighty-four patients diagnosed with GERD in The First People's Hospital of Hangzhou from December 2020 to December 2022 were enrolled in this study. They were divided into an observation group (Obs group, patients with GERD + CC, n = 26 cases) and a control group (control group, patients with typical GERD, n = 58 cases). Reflux symptom integral questionnaire, cough symptom integral questionnaire, high-res...
Source: Alternative Therapies in Health and Medicine - April 12, 2024 Category: Complementary Medicine Authors: Wenfang Liu Yuqing Tong Source Type: research

Effects of Anterior Fundoplication on Postoperative Dysphagia and Reflux After Laparoscopic Esophagocardiomyotomy for Pediatric Achalasia
Conclusion: In this largest observation of pediatric achalasia patients, A-fundo appeared clinically insignificant when determining contributors to control GER or exacerbate postoperative dysphagia. A-fundo should not be routinely adopted in children having L-ECM for achalasia without further multicenter analysis but appears beneficial in cases having inadvertent mucosal violation.PMID:38597929 | DOI:10.1089/lap.2023.0415 (Source: Adv Data)
Source: Adv Data - April 10, 2024 Category: Epidemiology Authors: Mary Peyton French Jordan Busing Sari Acra Heidi Chen Laura Stafman Irving Zamora Michael Holzman Harold N Lovvorn Source Type: research