Increased Use of Prophylactic Measures in Preventing Post-Endoscopic Retrograde Cholangiopancreatography Pancreatitis
ConclusionRectal  NSAIDs are the most applied post-ERCP pancreatitis prophylaxis in the Netherlands, followed by pancreatic duct stents and intensive intravenous hydration. Additionally, there is reason to believe that recent guideline updates and active research participation have led to increased prophylaxis impl ementation. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - February 25, 2021 Category: Gastroenterology Source Type: research

Cadmium Exposure in Young Adulthood Is Associated with Risk of Nonalcoholic Fatty Liver Disease in Midlife
This study included 2446 participants from the Coronary Artery Risk Development in Young Adults study with toenail Cd measurement at exam year 2 (baseline) and computed tomography quantification of liver fat at exam year 25. Toenail Cd concentrations were considered as a reliable marker of long-term exposure. NAFLD was defined if liver attenuation
Source: Digestive Diseases and Sciences - February 25, 2021 Category: Gastroenterology Source Type: research

Computed Tomography-Measured Liver Volume Predicts the Risk of Hepatocellular Carcinoma Development in Chronic Hepatitis C Patients
AbstractAimIn this retrospective cohort study, we evaluated the significance of liver volume in the prediction of hepatocellular carcinoma (HCC) in 277 chronic hepatitis C (CHC) patients who received dynamic computed tomography (CT) during surveillance.MethodsLiver volumes were measured on portal venous phase of CT images by using ImageJ software. Liver volume index, a ratio of the standard liver volume expected by weight and height to the measured liver volume, was calculated to adjust for normal variations. The cohort was randomly divided to derivation (n = 100) and validation sets (n = 177) f...
Source: Digestive Diseases and Sciences - February 25, 2021 Category: Gastroenterology Source Type: research

Circ_0006948 Contributes to Cell Growth, Migration, Invasion and Epithelial –Mesenchymal Transition in Esophageal Carcinoma
ConclusionTaken together, circ_0006948 functioned as an oncogenic factor in EC by the miR-4262-mediated FNDC3B expression regulation. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - February 25, 2021 Category: Gastroenterology Source Type: research

Knockdown of circRAD23B Exerts Antitumor Response in Colorectal Cancer via the Regulation of miR-1205/TRIM44 axis
ConclusionThese results suggested that the inhibition of circRAD23B retarded the progression of CRC via acting on the miR-1205/TRIM44 axis. CircRAD23B might be a novel target in CRC treatment. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - February 25, 2021 Category: Gastroenterology Source Type: research

Incidence and Risk of Pancreatic Cancer in Patients with a New Diagnosis of Chronic Pancreatitis
AbstractBackgroundChronic pancreatitis (CP) is a risk factor for pancreatic ductal adenocarcinoma (PDAC); nevertheless, the true incidence of PDAC in CP patients in the United States  remains unclear.AimsWe evaluated the risk of developing PDAC two or more years after a new diagnosis of CP.MethodsRetrospective study of veterans from September 1999 to October 2015. A three-year washout period was applied to exclude patients with preexisting CP and PDAC. PDAC risk was evaluated in patients with new-diagnosis CP and compared with controls without CP using Cox-proportional hazards model. CP, PDAC, and other covariates wer...
Source: Digestive Diseases and Sciences - February 25, 2021 Category: Gastroenterology Source Type: research

Endoscopic Bilateral Stent-in-Stent Versus Stent-by-Stent Deployment in Advanced Malignant Hilar Obstruction: A Meta-Analysis and Systematic Review
ConclusionsAlthough there was a lack of quality data and heterogeneity, bilateral SIS deployment had a higher technical feasibility than did the SBS method in patients with advanced MHO, without differences in terms of clinical success, adverse events, or occlusion rates. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - February 24, 2021 Category: Gastroenterology Source Type: research

Pancreatic Disorders in Patients with Inflammatory Bowel Disease
AbstractInflammatory bowel disease (IBD) can involve multiple organ systems, and pancreatic manifestations of IBD are not uncommon. The incidence of several pancreatic diseases is more frequent in patients with Crohn ’s disease and ulcerative colitis than in the general population. Pancreatic manifestations in IBD include a heterogeneous group of disorders and abnormalities ranging from mild, self-limited disorders to severe diseases. Asymptomatic elevation of amylase and/or lipase is common. The risk of acute pancreatitis in patients with IBD is increased due to the higher incidence of cholelithiasis and drug-induce...
Source: Digestive Diseases and Sciences - February 24, 2021 Category: Gastroenterology Source Type: research

Does Famotidine Reduce the Risk of Progression to Severe Disease, Death, and Intubation for COVID-19 Patients? A Systemic Review and Meta-Analysis
ConclusionFamotidine has no significant protective effect in reducing the risk of developing serious illness, death, and intubation for COVID-19 patients. More original studies are needed to further clarify whether it is associated with reduced risk of the severity, death, and intubation for COVID-19 patients. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - February 24, 2021 Category: Gastroenterology Source Type: research

Gastroenterology Fellowship Applicants ’ Perspectives on GI Program Preferences
AbstractGastroenterology fellowship continues to be highly competitive among internal medicine subspecialties. Recruiting excellent applicants is also important for GI fellowship program directors. We aim to examine factors that influence GI fellowship applicants ’ perspectives about a fellowship program. The authors conducted an anonymous online survey of applicants focusing on program characteristics including location, faculty, research/clinical opportunities, website, and interview day experience. Anonymous survey responses were recorded regarding prog ram characteristics, and subsequent candidate preferences wer...
Source: Digestive Diseases and Sciences - February 24, 2021 Category: Gastroenterology Source Type: research

More Than Just Heartburn: Does Famotidine Effectively Treat Patients with COVID-19?
(Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - February 24, 2021 Category: Gastroenterology Source Type: research

Hypogelsolinemia and Decrease in Blood Plasma Sphingosine-1-Phosphate in Patients Diagnosed with Severe Acute Pancreatitis
ConclusionPlasma gelsolin and S1P levels decrease during severe acute pancreatitis. Simultaneous assessment of pGSN and S1P can be useful in development of more accurate diagnostic strategies for patients with severe acute pancreatitis. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - February 23, 2021 Category: Gastroenterology Source Type: research

Effects of Spinal Cord Stimulation in Patients with Chronic Nausea, Vomiting, and Refractory Abdominal Pain
AbstractBackgroundPatients with chronic nausea and vomiting often also have chronic abdominal pain. Spinal cord stimulation (SCS) may provide pain control, but scarce data are available regarding the effect of SCS on chronic nausea and vomiting.AimsWe aimed to determine the effect of SCS in patients with chronic nausea, vomiting, and refractory abdominal pain.MethodsRetrospective chart review of 26 consecutive patients who underwent SCS trial for a primary diagnosis of nausea, vomiting and refractory abdominal pain.Results26 patients underwent SCS trial, with an average age of 48  years. Twenty-three patients (88.5%) ...
Source: Digestive Diseases and Sciences - February 23, 2021 Category: Gastroenterology Source Type: research

Impact of Fellow Participation During Colonoscopy on Adenoma Detection Rates
AbstractBackgroundAn endoscopist ’s adenoma detection rate (ADR) is inversely related to interval colorectal cancer risk and cancer mortality. Previous studies evaluating the impact of gastroenterology fellow participation in colonoscopy on ADR have generated conflicting results.AimsWe aimed to determine the impact of fellow participation, duration of fellowship training, and physician sex on ADR and advanced ADR (AADR).MethodsWe retrospectively analyzed average-risk patients undergoing screening colonoscopy at Veterans Affairs New York Harbor Healthcare System Brooklyn Campus and Kings County Hospital Center. Review...
Source: Digestive Diseases and Sciences - February 21, 2021 Category: Gastroenterology Source Type: research

Does Fellow Participation Increase the Adenoma Detection Rate?
(Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - February 21, 2021 Category: Gastroenterology Source Type: research

Author Spotlight: Andrew A. Li
(Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - February 21, 2021 Category: Gastroenterology Source Type: research

Author Spotlight: Noemi Zorzetti
(Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - February 21, 2021 Category: Gastroenterology Source Type: research

Update: Innate Lymphoid Cells in Inflammatory Bowel Disease
AbstractInflammatory bowel disease (IBD) is a chronic and nonspecific intestinal inflammatory condition with high relapse rate. Its pathogenesis has been linked to dysbacteriosis, genetic and environmental factors. In recent years, a new type of lymphocytes, termed innate lymphoid cells, has been described and classified into three subtypes of innate lymphoid cells —group 1, group 2 and group 3. An imbalance among these subsets’ interaction with gut microbiome, and other immune cells affects intestinal mucosal homeostasis. Understanding the role of innate lymphoid cells may provide ideas for developing novel an...
Source: Digestive Diseases and Sciences - February 20, 2021 Category: Gastroenterology Source Type: research

Patient Navigation After Positive Fecal Immunochemical Test Results Increases Diagnostic Colonoscopy and Highlights Multilevel Barriers to Follow-Up
ConclusionsAfter implementation of patient navigation, diagnostic colonoscopy was completed for 31.1% of patients with a positive FIT result. However, navigation also highlighted persistent multilevel barriers to follow-up. Future work will develop targeted solutions for these barriers to further increase FIT follow-up rates in our health system. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - February 20, 2021 Category: Gastroenterology Source Type: research

Paying Attention to Miss(ed) FITs
(Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - February 20, 2021 Category: Gastroenterology Source Type: research

Sex Moderates the Relationship Between Nausea Severity and Heart Rate Variability in Adolescents and Young Adults
ConclusionsThis is the first study to evaluate the relationship between nausea severity and HRV. Greater nausea severity was associated with lower HRV in females but not in males. Further validation of these results may provide insight into novel treatment approaches for females with nausea that target vagal tone. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - February 19, 2021 Category: Gastroenterology Source Type: research

Role of Liver Biopsy in Assessment of Radiologically Identified Liver Masses
ConclusionsIn patients with a radiologically identified liver mass of unclear etiology, liver biopsy/histology made a diagnosis in 95% (277/293) of patients, including 84% (246/293) found to have an oncological malignancy. Liver biopsy/histology also identified malignancy in a high proportion of patients without known underlying cancer. We conclude that liver biopsy is valuable for evaluation of radiologically identified liver masses of unclear etiology. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - February 19, 2021 Category: Gastroenterology Source Type: research

Renal Replacement Therapy for Acute Kidney Injury in Severe Alcohol-Associated Hepatitis as a Bridge to Transplant or Recovery
AbstractBackgroundAcute kidney injury is seen in approximately 30% of patients with severe alcohol-associated hepatitis (AH) and is associated with increased mortality. Controversy exists surrounding initiation of renal replacement therapy (RRT) in these patients, as most are ineligible for early transplantation.AimsThe primary aim was to identify predictors of survival and identify patients who may benefit from RRT as a bridge to transplant or recovery.MethodsA retrospective multicenter cohort of adult patients with AH, who received RRT, was developed, including patients from two North American and one European liver tran...
Source: Digestive Diseases and Sciences - February 19, 2021 Category: Gastroenterology Source Type: research

A Simple Emergency Department-Based Score Predicts Complex Hospitalization in Patients with Inflammatory Bowel Disease
We examined whether clinical, laboratory, and endoscopic markers at presentation predicted prolonged LOS, inpatient colectomy, or salvage therapy in IBD patients admitted with f lare.MethodsPatients with ulcerative colitis (UC) or colonic involvement of Crohn ’s disease (CD) hospitalized with flare and tested forClostridioides difficile infection (CDI) between 2010 and 2020 at two urban academic centers were studied. The primary outcome was complex hospitalization, defined as: LOS  >  7 days, inpatient colectomy, or inpatient infliximab or cyclosporine. A nested k-fold cross-validation identifie...
Source: Digestive Diseases and Sciences - February 19, 2021 Category: Gastroenterology Source Type: research

Acknowledgment of 2020 Reviewers
(Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - February 18, 2021 Category: Gastroenterology Source Type: research

Lymphoma in Pediatric-Onset Inflammatory Bowel Disease Treated with Infliximab Monotherapy: A Case Series
ConclusionsThis case series reports long-term follow-up for young patients with IBD who were treated with IFX monotherapy and developed lymphoma. Three of the five patients had bone involvement. In general, the risk of lymphoma following exposure to anti-TNF α medications alone remains low, but the incidence of primary bone lymphomas in IBD has not been reported. Studies examining longer exposure times may be needed to determine the true lymphoma risk in patients treated with IFX monotherapy. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - February 17, 2021 Category: Gastroenterology Source Type: research

The  Question That Doesn’t Seem to Go Away: Cancer Risk of Anti-TNF Therapy
(Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - February 17, 2021 Category: Gastroenterology Source Type: research

Development of a Large Colonoscopy-Based Longitudinal Cohort for Integrated Research of Colorectal Cancer: Partners Colonoscopy Cohort
ConclusionWe created the Partners Colonoscopy Cohort providing essential infrastructure for future studies to better understand the natural history of CRC and improve screening and post-polypectomy strategies. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - February 16, 2021 Category: Gastroenterology Source Type: research

Severe Upper Gastrointestinal Hemorrhage Caused by Reflux Esophagitis
ConclusionsFor patients with severe UGIB caused by RE, (1) the prevalence has increased significantly over the past three decades, (2) the reasons for this increase and preventive strategies warrant further study, (3) most patients lacked GERD symptoms and did not take acid suppressants, and (4) those with focal ulcers and SRH had more severe esophagitis and were treated endoscopically. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - February 16, 2021 Category: Gastroenterology Source Type: research

Comparative Efficacy of Various Pharmacological Interventions in the Treatment of Functional Dyspepsia: A Network Meta-Analysis
AbstractBackground and AimPatients with functional dyspepsia often select different pharmacological treatments. We aimed to compare and rank the efficacy of different pharmacological interventions in treating functional dyspepsia.MethodsWe searched EMBASE, PubMed, Cochrane, Web of Science and MEDLINE from the date of database inception to March 28, 2019. A random-effects model was selected to conduct traditional meta-analysis to directly examine the efficacy of different pharmacological interventions. The consistency model was selected to conduct a network meta-analysis to evaluate the relative effects and rank probability...
Source: Digestive Diseases and Sciences - February 15, 2021 Category: Gastroenterology Source Type: research

Role of eIF3C Overexpression in Predicting Prognosis of Intrahepatic Cholangiocarcinoma
ConclusionsElevated eIF3C expression promotes ICC development, and combination of eIF3C and KI67 is a valuable predictor of the survival and recurrence of ICC patient. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - February 12, 2021 Category: Gastroenterology Source Type: research

Pulmonary Artery Catheter in Patients with Severe Acute Pancreatitis: A Single-Center Retrospective Study
ConclusionIn patients with severe acute pancreatitis, PAC-guided fluid resuscitation shortened the duration of ICU stay, and patients in the PAC group had a lower rate of dependence on renal support, while no benefit in terms of mortality was observed. However, SAP patients inserted PAC within 24  h ICU admission showed shorter duration of renal support therapy and lower organ failure rates than those with 24–72 h ICU admission, indicating that early use of PAC, especially within 24 h, might be better for SAP patients. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - February 11, 2021 Category: Gastroenterology Source Type: research

Long Non-coding RNA FOXD2-AS1 Promotes Proliferation, Migration, and Invasion in Cholangiocarcinoma Through Regulating miR-760/E2F3 Axis
ConclusionsThis research revealed that lncRNA FOXD2-AS1 could enhance CCA malignant progression through regulating the miR-760/E2F3 axis and was expected to be a prognostic biomarker and therapeutic target for cholangiocarcinoma. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - February 11, 2021 Category: Gastroenterology Source Type: research

Author Spotlight: Manuel Zanni
(Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - February 11, 2021 Category: Gastroenterology Source Type: research

Protective Effect of Luminal Uric Acid Against Indomethacin-Induced Enteropathy: Role of Antioxidant Effect and Gut Microbiota
ConclusionsThe protective role of luminal UA in intestinal injury is likely exerted via oxidative stress elimination and microbiota composition modulation, preferably for gut immunity. Therefore, enhancing anaerobic conditions using antioxidants is a potential therapeutic target. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - February 11, 2021 Category: Gastroenterology Source Type: research

Two Strikes but Not Out: Deep Remission of Ulcerative Colitis with Ustekinumab After Primary Non-response to Infliximab and Vedolizumab
(Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - February 11, 2021 Category: Gastroenterology Source Type: research

Advanced Liver Fibrosis Is Associated with Necroinflammatory Grade but Not Hepatic Steatosis in Chronic Hepatitis B Patients
AbstractBackground and AimsPatients with chronic hepatitis B (CHB) are at an increased risk of disease progression. The influence of hepatic steatosis (HS) to liver fibrosis was controversial. We aim to investigate the association between HS and liver fibrosis and explore the predicting factors for advanced fibrosis.MethodsCHB patients undergoing liver biopsy with complete assessments of HS, necroinflammation grade [histological activity index (HAI) score], and fibrosis stage were retrospectively recruited. Logistic regression analysis was performed to determine the factors associated with advanced liver fibrosis.ResultsIn...
Source: Digestive Diseases and Sciences - February 10, 2021 Category: Gastroenterology Source Type: research

Insulin-Like Growth Factor 1 Receptor Drives Hepatocellular Carcinoma Growth and Invasion by Activating Stat3-Midkine-Stat3 Loop
ConclusionsConstitutive activation of the IGF-1R-mediated Stat3-Midkine-Stat3 positive feedback loop is present in HCC, the inhibition of which can serve as a potential therapeutic intervention strategy for HCC. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - February 9, 2021 Category: Gastroenterology Source Type: research

Efficacy and Safety of Antofloxacin-Based Triple Therapy for Helicobacter pylori Eradication Failure in China
ConclusionsThe findings showed that antofloxacin may be a promising candidate in rescue therapy forH. pylori eradication failure in China. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - February 8, 2021 Category: Gastroenterology Source Type: research

Performance of Serum-Based Scores for Identification of Mild Hepatic Steatosis in HBV Mono-infected and HBV –HIV Co-infected Adults
AbstractBackgroundThere are limited data on noninvasive methods to identify hepatic steatosis in coexisting hepatitis B virus (HBV) infection.AimsTo evaluate the diagnostic performance of noninvasive serum-based scores to detect steatosis using two distinct chronic HBV cohorts with liver histology evaluation.MethodsChronic HBV cohorts with untreated HBV mono-infection (N = 302) and with treated HBV–HIV (N = 92) were included. Liver histology was scored centrally. Four serum-based scores were calculated: hepatic steatosis index (HSI), nonalcoholic fatty liver disease Liver Fat Score (NAFLD-...
Source: Digestive Diseases and Sciences - February 8, 2021 Category: Gastroenterology Source Type: research

HIF1A-AS2 Promotes the Proliferation and Metastasis of Gastric Cancer Cells Through miR-429/PD-L1 Axis
ConclusionHIF1A-AS2 is a dependable predictor of malignancy and prognosis in GC and functions as an oncogene to promote GC cell proliferation and metastasis by regulating miR-429/PD-L1 axis, indicating a new insight into the search for novel biomarkers and therapeutic strategies. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - February 8, 2021 Category: Gastroenterology Source Type: research

Circ_0091579 Serves as a Tumor-Promoting Factor in Hepatocellular Carcinoma Through miR-1225-5p/PLCB1 Axis
ConclusionCirc_0091579 knockdown repressed HCC progression and tumorigenesis by regulating miR-1225-5p/PLCB1 axis, affording a novel molecular basis for HCC development. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - February 8, 2021 Category: Gastroenterology Source Type: research

Alcohol Aggravates Acute Pancreatitis by Impairing Autophagic Flux Through Activation of AMPK Signaling Pathway
ConclusionAlcohol aggravates AP progression by impairing autophagic flux and enhancing cell autophagy through the AMPK signaling pathway. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - February 8, 2021 Category: Gastroenterology Source Type: research

Special FX: Harnessing the Farnesoid-X-Receptor to Control Bile Acid Synthesis
(Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - February 8, 2021 Category: Gastroenterology Source Type: research

Correction to: Understanding Determinants of Patient Preferences Between Stool Tests and Colonoscopy for the Assessment of Disease Activity in Inflammatory Bowel Disease
The original version of the article unfortunately contained an error in the acknowledgment content. The corrected acknowledgment with the UCSD Gastroenterology T32 training grant (DK 0,070,202) is given below. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - February 8, 2021 Category: Gastroenterology Source Type: research

Use of Artificial Intelligence in the Prediction of Malignant Potential of Gastric Gastrointestinal Stromal Tumors
ConclusionsAI via a deep learning algorithm using EUS images could predict the malignant potential of gastric GISTs with high accuracy.Graphic Abstract (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - February 6, 2021 Category: Gastroenterology Source Type: research

Serum Globulin Is Associated with Endoscopic Findings and Mucosal Healing in Japanese Patients with Ulcerative Colitis
ConclusionsIn patients with ulcerative colitis, serum globulin was significantly positively associated with endoscopic activity, and was significantly inversely associated with mucosal healing, especially in the low C-reactive protein group. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - February 4, 2021 Category: Gastroenterology Source Type: research

A Prognostic Prediction Model of Transarterial Radioembolization in Hepatocellular Carcinoma: SNAP-HCC
AbstractBackgroundPrognosis prediction in patient with hepatocellular carcinoma (HCC) after transarterial radioembolization (TARE) remains difficult. The aim of this study was to develop a prognostic model to aid in the decision to use TARE.MethodsA total of 174 patients in Korea who underwent TARE for HCC as the initial treatment were included. We developed a prediction model for overall survival (OS) based on independent risk factors for OS and validated the model by bootstrap method.ResultsThe median maximal size of the tumors was 8.2  cm, the median number of tumors was 2, and the median albumin level was 4.0 ...
Source: Digestive Diseases and Sciences - February 4, 2021 Category: Gastroenterology Source Type: research

Novel Case Report: A Previously Reported, but Pathophysiologically Unexplained, Association Between Collagenous Colitis and Protein-Losing Enteropathy May Be Explained by an Undetected Link with Collagenous Duodenitis
AbstractCollagenous colitis (CC) is associated with non-bloody, watery diarrhea, which is pathophysiologically reasonable because normal colonic absorption (or excretion) of water and electrolytes can be blocked by the abnormally thick collagen layer in CC. However, CC has also been associated with six previous cases of protein-losing enteropathy (PLE), with no pathophysiologic explanation. The colon does not normally absorb (or excrete) amino acids/proteins, which is primarily the function of the small bowel. Collagenous duodenitis (CD) has not been associated with PLE. This work reports a novel case of CD (and CC)associa...
Source: Digestive Diseases and Sciences - February 4, 2021 Category: Gastroenterology Source Type: research

Correction to: Laparoscopic Duodenojejunostomy for Superior Mesenteric Artery Syndrome
The original version of the article unfortunately contained an error in one of the authors name in the author group. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - February 4, 2021 Category: Gastroenterology Source Type: research