Importance of Hepcidin in the Etiopathogenesis of Anemia in Inflammatory Bowel Disease
AbstractAnemia is the most common extraintestinal systemic complication of inflammatory bowel disease. Iron deficiency anemia and anemia of chronic disease are among the most frequent types. Intestinal iron absorption is controlled by the activity of ferroportin. Cells with high expression of ferroportin include enterocytes, and also macrophages and hepatocytes. Iron homeostasis is controlled by the hepcidin-ferroportin axis. Hepcidin is a central regulator of iron metabolism and can also serve as a marker of systemic inflammation. During systemic inflammatory response, the synthesis of hepcidin increases, and hepcidin bin...
Source: Digestive Diseases and Sciences - October 16, 2020 Category: Gastroenterology Source Type: research

Impaired Quality of Working Life in Inflammatory Bowel Disease Patients
AbstractBackgroundWork-related aspects are important determinants of health for inflammatory bowel disease (IBD) patients.AimsWe aimed to describe quality of working life (QWL) in IBD patients and to assess variables that are associated with QWL.MethodsEmployed IBD patients of two tertiary and two secondary referral hospitals were included. QWL (range 0 –100) was measured using the Quality of Working Life Questionnaire (QWLQ). Work productivity (WP), fatigue, and health-related quality of life (HRQL) were assessed using the Work Productivity and Activity Impairment questionnaire, Multidimensional Fatigue Inventory, a...
Source: Digestive Diseases and Sciences - October 16, 2020 Category: Gastroenterology Source Type: research

Factors Associated with Up-to-Date Colonoscopy Use Among Puerto Ricans in New York City, 2003 –2016
ConclusionsOlder age, influenza vaccination, having a primary care provider, and exercise are independent predictors of up-to-date colonoscopy use among Puerto Ricans in NYC. Interventions to improve screening colonoscopy uptake among Puerto Ricans should be targeted to those aged 50 –64 years and who do not have a primary care provider. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - October 16, 2020 Category: Gastroenterology Source Type: research

Bad “Good” Bile Acids and Gut Microbiota Dysbiosis in Inflammatory Bowel Disease: Mice and Humans Are Not the Same
AbstractThe effects of deoxycholic acid (DCA) on the intestinal microbiota, bile acid (BA) metabolism, and intestinal epithelium can be influenced by various factors. Depending on the specific conditions, DCA can be “bad” (proinflammatory) or “good” (anti-inflammatory). Mouse models of colitis show an increase in conjugated BAs and gut dysbiosis, including DCA-related dysbiosis, with a significant decrease in bile salt hydrolase (bsh) gene-containing taxa. Human patients with inflammatory bowel disease demonstrate, primarily, a decrease in bile acid-inducible (bai) gene-containing taxa and a deficie...
Source: Digestive Diseases and Sciences - October 16, 2020 Category: Gastroenterology Source Type: research

Pilot Validation of a New Wireless Patch System as an Ambulatory, Noninvasive Tool That Measures Gut Myoelectrical Signals: Physiologic and Disease Correlations
ConclusionsThe novel WPS technology, measuring myoelectric intestinal activity noninvasively and continuously over multiple days, is feasible in a wide range of clinical settings, highlighting its promise in the diagnosis and management of motility disorders. Further research is required for more extensive validation and to determine how best to employ this information to optimize patient care. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - October 15, 2020 Category: Gastroenterology Source Type: research

Microscopic Colitis Is Not an Independent Risk Factor for Low Bone Density
AbstractBackgroundMicroscopic colitis (MC) is a subtype of inflammatory bowel disease (IBD) with overlapping risk factors for low bone density (LBD). While LBD is a known complication of IBD, its association with MC is not well-established.AimsAssess the prevalence of LBD in MC compared to control populations, and evaluate if MC predicts LBD when controlling for confounders.MethodsRetrospective, observational case control study of adult patients with pathologically confirmed MC from 2005 to 2015. Bone density measurements were abstracted from dual-energy X-ray absorptiometry (DEXA) reports, and bone density was classified ...
Source: Digestive Diseases and Sciences - October 15, 2020 Category: Gastroenterology Source Type: research

Artificial Intelligence and Its Role in Identifying Esophageal Neoplasia
AbstractRandomized trials have demonstrated that ablation of dysplastic Barrett ’s esophagus can reduce the risk of progression to cancer. Endoscopic resection for early stage esophageal adenocarcinoma and squamous cell carcinoma can significantly reduce postoperative morbidity compared to esophagectomy. Unfortunately, current endoscopic surveillance technologies (e.g., high- definition white light, electronic, and dye-based chromoendoscopy) lack sensitivity at identifying subtle areas of dysplasia and cancer. Random biopsies sample only approximately 5% of the esophageal mucosa at risk, and there is poor agreement a...
Source: Digestive Diseases and Sciences - October 15, 2020 Category: Gastroenterology Source Type: research

PLCD1: A Potential Therapeutic Target in the Treatment of Esophageal Squamous Cell Carcinoma?
(Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - October 15, 2020 Category: Gastroenterology Source Type: research

Red Between the Lines: Evolution of Eosinophilic Esophagitis as a Distinct Clinicopathologic Syndrome
AbstractEosinophilic esophagitis (EoE) is characterized by eosinophilic infiltration of the esophageal mucosa and symptoms of esophageal dysfunction, including dysphagia. While EoE is still considered a rare disease, in practice it seems that more and more cases are diagnosed every week, research in the field is exploding, and the pipeline for treatments contains multiple agents, some of which are quite far along the development pathway. After only scattered cases and small series were published in the late 1970s and 1980, Stephen Attwood, Thomas Smyrk, Tom DeMeester, and James Jones, published in Digestive Diseases and Sc...
Source: Digestive Diseases and Sciences - October 14, 2020 Category: Gastroenterology Source Type: research

Tongue Coating Bacteria as a Potential Stable Biomarker for Gastric Cancer Independent of Lifestyle
ConclusionsThe alteration of tongue coating microbiota had a possible linkage with the inflammations and metabolome, and the tongue coating bacteria could be a potential noninvasive biomarker for diagnosing GC, which might be independent of lifestyle. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - October 12, 2020 Category: Gastroenterology Source Type: research

Prevalence, Indirect Costs, and Risk Factors for Work Disability in Patients with Crohn ’s Disease at a Tertiary Care Center in Rio de Janeiro
ConclusionsIn Rio de Janeiro, work disability affects one-sixth of CD patients, and risk factors are associated with disease duration and complications. In the context of increasing prevalence, as this disability compromises young patients after a relatively short period of disease, the socioeconomic burden of CD is expected to increase in the future. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - October 12, 2020 Category: Gastroenterology Source Type: research

Inositol-Requiring Kinase 1 Regulates Apoptosis via Inducing Endoplasmic Reticulum Stress in Colitis Epithelial Cells
ConclusionsInhibition of IRE-1 enhanced unfolded protein response and cells apoptosis and IL-6-induced ERS and suggested that IRE-1 might be a potential target of UC. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - October 12, 2020 Category: Gastroenterology Source Type: research

Circ_0091581 Promotes the Progression of Hepatocellular Carcinoma Through Targeting miR-591/FOSL2 Axis
ConclusionCirc_0091581 acted as an oncogene to enhance the viability, colony formation, metastasis and cell cycle and inhibit the apoptosis of HCC cells through targeting miR-591/FOSL2 axis. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - October 11, 2020 Category: Gastroenterology Source Type: research

Infliximab Trough Levels Are Not Predictive of Relapse in Patients with IBD in Endoscopic Remission: A Multicenter Cohort Study
AbstractBackgroundTherapeutic drug monitoring (TDM) is important in optimizing use of biologics in inflammatory bowel diseases (IBD). However, the role of proactive TDM during remission remains uncertain.MethodsThis retrospective study included patients receiving infliximab (IFX) therapy at Massachusetts General Hospital or Erasmus University Medical Center. All eligible patients had completed induction phase of IFX and were in clinical and endoscopic remission. Our primary outcome was clinical relapse within 2  years after baseline. Multivariable regression models examined the association between infliximab trough le...
Source: Digestive Diseases and Sciences - October 10, 2020 Category: Gastroenterology Source Type: research

Small Intestinal Bacterial Overgrowth Syndrome: A Guide for the Appropriate Use of Breath Testing
AbstractThe increased availability of noninvasive breath tests, each with limitations, has led to widespread testing for small intestinal bacterial overgrowth (SIBO) in patients with non-specific gastrointestinal complaints. The lactulose breath test (LBT) is based upon an incorrect premise and therefore incorrect interpretations which has resulted in the over-diagnosis of SIBO and the excessive use of antibiotics in clinical practice. Despite limitations, the glucose breath test (GBT) should be exclusively employed when considering SIBO in appropriately chosen patients. This review suggests guidelines for the optimal use ...
Source: Digestive Diseases and Sciences - October 10, 2020 Category: Gastroenterology Source Type: research

Incident Dementia in Elderly Patients with Nonalcoholic Fatty Liver Disease in Germany
In conclusion, in this database study of elderly patients coded with NAFLD no independent association with incident dementia was detected. Risk assessment regarding dementia in patients with NAFLD should be carried out in the same way as for metabolic burdened patients. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - October 10, 2020 Category: Gastroenterology Source Type: research

Correction to: Characterization of Creatine Kinase Levels in Tofacitinib ‑Treated Patients with Ulcerative Colitis: Results from Clinical Trials
The article “Characterization of Creatine Kinase Levels in Tofacitinib–Treated Patients with Ulcerative Colitis: Results from Clinical Trials”, written by Remo Panaccione, John D. Isaacs, Lea Ann Chen, Wenjin Wang, Amy Marren, Kenneth Kwok, Lisy Wang, Gary Chan and Chinyu Su, was originally published electronically on the publisher’s internet portal on 20 August 2020 without open access. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - October 10, 2020 Category: Gastroenterology Source Type: research

Safety of Chronic Simvastatin Treatment in Patients with Decompensated Cirrhosis: Many Adverse Events but No Liver Injury
ConclusionsChronic treatment with simvastatin 40  mg/day in patients with decompensated cirrhosis was associated with several adverse events, being MI the only clinically significant one, which appears to be related to the simvastatin dosage and the degree of cirrhosis severity. Noticeably, no liver injury was recorded. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - October 9, 2020 Category: Gastroenterology Source Type: research

Simplifying Measurement of Adenoma Detection Rates for Colonoscopy
ConclusionsMeasuring ADR using administrative codes and text searches from pathology results is an efficient method to broadly survey colonoscopy quality. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - October 8, 2020 Category: Gastroenterology Source Type: research

TUG1 as a Therapy Target in Pancreatic Cancer
(Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - October 6, 2020 Category: Gastroenterology Source Type: research

What GI Physicians Need to Know During COVID-19 Pandemic
AbstractThe worldwide pandemic of COVID-19, caused by the virus SARS-CoV-2, continues to cause significant morbidity and mortality in both low- and high-income countries. Although COVID-19 is predominantly a respiratory illness, other systems including gastrointestinal (GI) system and liver may be involved because of the ubiquitous nature of ACE-2 receptors in various cell lines that SARS-CoV-2 utilizes to enter host cells. It appears that GI symptoms and liver enzyme abnormalities are common in COVID-19. The involvement of the GI tract and liver correlates with the severity of disease. A minority (10 –20%) of patien...
Source: Digestive Diseases and Sciences - October 4, 2020 Category: Gastroenterology Source Type: research

Clearing of the Clouds in Inflammatory Bowel Disease Management
AbstractThe skies over inflammatory bowel disease care are beginning to clear. Success is being achieved in the management of inflammatory bowel disease due to ongoing research, new medications, and most significantly to the recognition of the importance of patient selection and the definition of remission. Five answered questions provide the basis for recent successes and forecast for clearing of the clouds. How do we classify the inflammatory bowel disease (IBD) patient? How do we select our medications to best match the patients ’ classifications? How do we monitor and manage medications during the course of care?...
Source: Digestive Diseases and Sciences - October 2, 2020 Category: Gastroenterology Source Type: research

Guidelines for the Perplexed: How to Maximize Colonoscopy Efficiency During the COVID-19 Pandemic
(Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - September 30, 2020 Category: Gastroenterology Source Type: research

Improving the Safety of Endoscopy in Pregnancy: Approaching Gravidity with Gravitas
(Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - September 15, 2020 Category: Gastroenterology Source Type: research

Assurance for Endurance? Introducing a Novel Ergonomics Curriculum to Reduce Pain and Enhance Physical Well-Being Among GI Fellows
AbstractMusculoskeletal pain and injuries (MSKPI) are common among gastroenterologists (GI) and GI fellows. Common areas of pain include the back, neck, hands/fingers, shoulders, and elbows. Although the prevalence of career-related pain and injuries among GIs is high, few endoscopists receive training in how to prevent MSKPI. We developed an ergonomics curriculum for our GI fellows that consisted of two modules that were led by physical therapists. Twelve out of 15 GI fellows, and one out of two hepatology fellows, participated in Module 1. Prior to the first module, 77% of participants reported pain in one or more body p...
Source: Digestive Diseases and Sciences - September 15, 2020 Category: Gastroenterology Source Type: research

NAFLD and Statins
(Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - September 15, 2020 Category: Gastroenterology Source Type: research

Concomitant Heterotopic Pancreas and Endometriosis as a Rare Cause of Ileo-Ileal Intussusception in a Young Woman with Spina Bifida: Case Report and Literature Review
We report a case of a 33-year-old female patient with spina bifida admitted to the Emergency Surgical Department for ileal intussusception due to the presence of heterotopic pancreas associated with endometriosis.Areas CoveredSymptomatic ileal intussusception for ectopic pancreas is usually associated with overt gastrointestinal blood loss (predominantly melena), abdominal pain, vomiting, and weight loss. Treatment is universally surgical.Expert CommentaryIsolated heterotopic pancreas is a rare condition; it should be considered in the differential diagnosis of bowel intussusception. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - September 15, 2020 Category: Gastroenterology Source Type: research

Author Spotlight: Matthew S. Sussman
(Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - September 15, 2020 Category: Gastroenterology Source Type: research

Author Spotlight: Andrea Sciannamea
(Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - September 15, 2020 Category: Gastroenterology Source Type: research

Author Spotlight: Morgan A. Sendzischew Shane
(Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - September 15, 2020 Category: Gastroenterology Source Type: research

Interleukin-17 as a Therapy Target in Intestinal Fibrosis
(Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - September 15, 2020 Category: Gastroenterology Source Type: research

Femoral Vein Wall Thickness Measurement May Be a Distinctive Diagnostic Tool to Differentiate Beh çet’s Disease with Intestinal Involvement and Crohn’s Disease
ConclusionWe found significantly lower CFV thickness in CD compared to BD. Our results suggest that CFV wall thickness measurement is a distinctive diagnostic tool for the differentiation of BD and CD and can be helpful in daily practice for the differentiation of two diseases. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - September 13, 2020 Category: Gastroenterology Source Type: research

Disparities in Mortality and Health Care Utilization for 460,851 Hospitalized Patients with Cirrhosis and Hepatic Encephalopathy
In this study, we proposed to investigate recent trends in in-hospital mortality and utilization for patients with cirrhosis and HE and to explore the effect of various sociodemographic, hospital, and clinical factors on mortality.MethodsWe performed an observational study using serial cross-sectional data from the 2009 –2013 National Inpatient Sample to examine hospitalizations of patients with cirrhosis and HE. We collected data on in-hospital mortality, length of stay, and total hospital costs. We used negative binomial regression and logistic regression to investigate trends in utilization and multilevel mode lin...
Source: Digestive Diseases and Sciences - September 13, 2020 Category: Gastroenterology Source Type: research

The Clinical Significance of Anastomotic Ulcers After Ileocolic Resection to Predict Postoperative Recurrence of Crohn ’s Disease
AbstractBackgroundThe Rutgeerts score is used to predict postoperative recurrence in CD patients after ileocolic resection and is primarily based on endoscopic findings at the neoterminal ileum. However, the optimal assessment of anastomotic ulcers (AUs) remains subject to debate.AimsWe aimed to investigate the association between anastomotic ulcers (AUs) and endoscopic recurrence in postoperative Crohn ’s disease (CD) patients.MethodsThis single-center retrospective study, conducted between 2000 and 2016, evaluated postoperative CD patients with endoscopic remission at the first ileocolonoscopy within 1  year a...
Source: Digestive Diseases and Sciences - September 13, 2020 Category: Gastroenterology Source Type: research

Comments on ‘Initial Computed Tomography Findings of Long and Distended Colon Are Risk Factors for the Recurrence of Sigmoid Volvulus’
(Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - September 13, 2020 Category: Gastroenterology Source Type: research

Adding Thiopurine After Loss of Response to Infliximab Versus Early Combination in Treating Crohn ’s Disease: A Retrospective Study
ConclusionConsidering the risk –benefit balance, delayed addition of thiopurine after LOR to IFX might be an alternative strategy when using IFX to treat CD. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - September 12, 2020 Category: Gastroenterology Source Type: research

SNHG10 Promotes Cell Proliferation and Migration in Gastric Cancer by Targeting miR-495-3p/CTNNB1 Axis
ConclusionsSNHG10 promotes the procession of GC through targeting miR-495-3p/CTNNB1 and activating WNT signaling pathway. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - September 11, 2020 Category: Gastroenterology Source Type: research

I Can C Clearly Now: How EPEC Inhibits Gut Vitamin C Transport by Dysregulating SVCT
(Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - September 11, 2020 Category: Gastroenterology Source Type: research

Portal Venous Flow Is Increased by Jejunal but Not Colonic Hydrogen Sulfide in a Nitric Oxide-Dependent Fashion in Rats
AbstractHydrogen sulfide (H2S) is a recently discerned endogenous signaling molecule that modulates the vascular system. Endogenous hydrogen sulfide has been shown to dilate both the mesenteric and portal vasculature. Gut microbiome, via sulfur reducing bacteria, is another source of H2S production within the gut lumen; this source of H2S is primarily produced and detoxified in the colon under physiologic conditions. Nitric oxide (NO), a major endogenous vasodilator in the portal circulation, participates in H2S-induced vasodilation in some vascular beds. We hypothesize that jejunal but not colonic H2S increases portal vei...
Source: Digestive Diseases and Sciences - September 10, 2020 Category: Gastroenterology Source Type: research

MiR-325 Promotes Oxaliplatin-Induced Cytotoxicity Against Colorectal Cancer Through the HSPA12B/PI3K/AKT/Bcl-2 Pathway
ConclusionsMiR-325 sensitizes the colorectal cancer cells to oxaliplatin-induced cytotoxicity through the HSPA12B/PI3K/AKT/Bcl-2 pathway. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - September 9, 2020 Category: Gastroenterology Source Type: research

LncRNA FAM230B Promotes Gastric Cancer Growth and Metastasis by Regulating the miR-27a-5p/TOP2A Axis
ConclusionOur study showed that lncRNA FAM230B might function to promote GC. FAM230B functioned as a ceRNA by sponging miR-27a-5p and enhancing TOP2A expression. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - September 9, 2020 Category: Gastroenterology Source Type: research

Impact of a Virtual Endoscopy Training Curriculum in Novice Endoscopists: First Experience in Argentina
ConclusionsVirtual endoscopy training curriculum produces a significant improvement in the trainee endoscopists performance and their psychomotor skills and introduces the concept of a quality endoscopic study in a non-patient, risk-free environment. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - September 9, 2020 Category: Gastroenterology Source Type: research

The Mettle to Use the Petals: Using Over-the-Scope Rings to Optimize Endoscopic Submucosal Dissection
(Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - September 9, 2020 Category: Gastroenterology Source Type: research

Different Performance of Liver Stiffness Measurement According to Etiology and Outcome for the Prediction of Liver-Related Events
ConclusionsLSM showed powerful prognostic role for the prediction of LRE in patients with CLD. Notably, HCC risk was not negligible in patients with viral hepatitis who showed LSM value  
Source: Digestive Diseases and Sciences - September 7, 2020 Category: Gastroenterology Source Type: research

Patient, Physician, and Procedure Characteristics Are Independently Predictive of Polyp Detection Rates in Clinical Practice
ConclusionsIn a multi-level model accounting for clustering effects, we identified patient, provider and procedural factors independently influence adenoma and sessile serrated polyp detection. Our findings suggest that to compare polyp detection rates between endoscopists, even at the same institution, risk adjustment by characteristics of the patient population and practice is necessary. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - September 6, 2020 Category: Gastroenterology Source Type: research

Nonalcoholic Fatty Liver Disease Is Common in IBD Patients However Progression to Hepatic Fibrosis by Noninvasive Markers Is Rare
ConclusionsIBD patients with NAFLD tend to have stable liver disease over 4 –6 years, and the risk of liver disease progression is low. This is the first study to document the progression of NAFLD by noninvasive testing over time. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - September 6, 2020 Category: Gastroenterology Source Type: research

Observations on the Effect of Electronic Needle Container on Adherence to Adalimumab
(Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - September 6, 2020 Category: Gastroenterology Source Type: research

Concise Commentary: Ironing Out the Differences –Healthcare Disparities in the Evaluation of IDA and Diarrhea
(Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - September 6, 2020 Category: Gastroenterology Source Type: research

Clinical Outcomes of Acute Pancreatitis in Patients with Cirrhosis According to Liver Disease Severity Scores
AbstractBackgroundLiterature on acute pancreatitis (AP) outcomes in patients with cirrhosis is limited. We aim to investigate the mortality and morbidity of AP in patients with cirrhosis.MethodsWe conducted a retrospective cohort study, and propensity score matching was done to match cirrhotic with non-cirrhotic patients on a 1:2 basis. Outcomes included inpatient mortality, organs failure, systemic inflammatory response syndrome, and length of hospital stay. We performed subgroup analysis of cirrhotics according to Child –Pugh and MELD scores. Multivariable logistic regression models were tested.ResultsFrom 819 AP p...
Source: Digestive Diseases and Sciences - September 5, 2020 Category: Gastroenterology Source Type: research

Anemia Severity Associated with Increased Healthcare Utilization and Costs in Inflammatory Bowel Disease
AbstractBackgroundAnemia is a common systemic complication of inflammatory bowel disease (IBD) and is associated with worse disease outcomes, quality of life, and higher healthcare costs.AimsThe purpose of this study was to determine how anemia severity impacts healthcare resource utilization and if treatment of anemia was associated with reduced utilization and costs.MethodsRetrospective chart review of adult patients managed by gastroenterology between 2014 and 2018 at a tertiary referral center.ResultsThe records of 1763 patients with IBD were included in the analysis, with 966 (55%) patients with CD, 799 (44%) with UC,...
Source: Digestive Diseases and Sciences - September 4, 2020 Category: Gastroenterology Source Type: research