Effectiveness of Tofacitinib in Ulcerative Proctitis Compared to Left Sided Colitis and Pancolitis
ConclusionThe effectiveness of tofacitinib in inducing and maintaining clinical remission is greater in patients with UP compared to LSC and PC.Graphical Abstract (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - February 15, 2024 Category: Gastroenterology Source Type: research

Exosomes from Intrahepatic Cholestasis of Pregnancy Induce Cell Apoptosis Through the miRNA-6891-5p/YWHAE Pathway
ConclusionsThis study indicates that serum exosomes from ICP patients can impact the apoptosis of placental trophoblast HTR-8/SVeno cells through the miR-6891-5P/YWHAE pathway and can serve as specific molecular markers for ICP diagnosis.Graphical Abstract (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - February 15, 2024 Category: Gastroenterology Source Type: research

Antibiotics for Dyspepsia: Hp, SIBO, IMO, or Something Else?
(Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - February 15, 2024 Category: Gastroenterology Source Type: research

Correction: In Patients with Bleeding, Delaying Cardiac Catheterization in Favor of Endoscopy in Non-ST Elevation Myocardial Infarction Can Prevent Severe Bleeding on Dual Antiplatelet Therapy if Needed
(Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - February 15, 2024 Category: Gastroenterology Source Type: research

Homeobox Protein BarH-like 1 Promotes Gastric Cancer Progression by Activating Coiled-Coil Domain-Containing Protein 178
ConclusionsBARX1 activates the transcription of CCDC178 to induce the ERK pathway, thereby supporting macrophage recruitment and M2-like polarization in GC.Graphical Abstract (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - February 15, 2024 Category: Gastroenterology Source Type: research

Influence of Helicobacter pylori Infection and Eradication on Small Intestinal Bacterial Overgrowth and Abdominal Symptoms
ConclusionHelicobacter pylori infection was associated with higher prevalence of SIBO and IMO, both of which led to more pronounced abdominal symptoms.H. pylori eradication also achieved therapeutic effects on SIBO and IMO, accompanied by relief of abdominal symptoms. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - February 15, 2024 Category: Gastroenterology Source Type: research

Bovine Colostrum Increases Intestinal Permeability in Healthy Athletes and Patients: A Meta-Analysis of Randomized Clinical Trials
ConclusionsBC supplementation significantly reduced intestinal permeability; however, to confirm the results, more randomized clinical trials considering different quality, dose, and duration are needed.Graphical Abstract (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - February 15, 2024 Category: Gastroenterology Source Type: research

Exosomes from Intrahepatic Cholestasis of Pregnancy Induce Cell Apoptosis Through the miRNA-6891-5p/YWHAE Pathway
ConclusionsThis study indicates that serum exosomes from ICP patients can impact the apoptosis of placental trophoblast HTR-8/SVeno cells through the miR-6891-5P/YWHAE pathway and can serve as specific molecular markers for ICP diagnosis.Graphical Abstract (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - February 15, 2024 Category: Gastroenterology Source Type: research

Antibiotics for Dyspepsia: Hp, SIBO, IMO, or Something Else?
(Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - February 15, 2024 Category: Gastroenterology Source Type: research

Effectiveness of Tofacitinib in Ulcerative Proctitis Compared to Left Sided Colitis and Pancolitis
ConclusionThe effectiveness of tofacitinib in inducing and maintaining clinical remission is greater in patients with UP compared to LSC and PC.Graphical Abstract (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - February 15, 2024 Category: Gastroenterology Source Type: research

Correction: In Patients with Bleeding, Delaying Cardiac Catheterization in Favor of Endoscopy in Non-ST Elevation Myocardial Infarction Can Prevent Severe Bleeding on Dual Antiplatelet Therapy if Needed
(Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - February 15, 2024 Category: Gastroenterology Source Type: research

BEST-J Score: Validation of a Predicting Model for Delayed Bleeding After Gastric Endoscopic Submucosal Dissection on a European Sample
ConclusionsThe BEST-J score still presents excellent accuracy in risk stratification for post-ESD bleeding in European individuals. Thus, this score may help to guide which patients benefit the most from prophylactic therapies following gastric ESD in this setting. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - February 14, 2024 Category: Gastroenterology Source Type: research

Risk Stratification in Primary Sclerosing Cholangitis: Does Size Matter?
(Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - February 12, 2024 Category: Gastroenterology Source Type: research

Primary Sclerosing Cholangitis Limited to Intrahepatic Bile Ducts Has Distinctly Better Prognosis
ConclusionsPatients with IIPSC have a favorable prognosis similar to small-duct PSC. These data are important for counseling patients and designing therapeutic trials for PSC. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - February 12, 2024 Category: Gastroenterology Source Type: research