Contribution of High Body Mass Index to the Global Burden of Esophageal Cancer: A Population-Based Study from 1990 to 2019
ConclusionsThe study provided a comprehensive understanding of the global burden of EC associated with high BMI over the past decades. Opportunities exist to reduce this burden at all SDI levels through targeted interventions and policies. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - March 3, 2024 Category: Gastroenterology Source Type: research

Relationship of Age and Gender to Motility Test Results and Symptoms in Patients with Chronic Constipation
ConclusionsThere are significant age- and gender-related differences in symptoms, CTT, and HR-HRM parameters, rectal sensation, and expulsion, that may influence the multifaceted management of constipation. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - March 2, 2024 Category: Gastroenterology Source Type: research

Successful Removal of Gallbladder Stones Under Direct Visualization of Single-Operator Peroral Cholangioscopy (with Video)
(Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - March 2, 2024 Category: Gastroenterology Source Type: research

Relationship of Age and Gender to Motility Test Results and Symptoms in Patients with Chronic Constipation
ConclusionsThere are significant age- and gender-related differences in symptoms, CTT, and HR-HRM parameters, rectal sensation, and expulsion, that may influence the multifaceted management of constipation. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - March 2, 2024 Category: Gastroenterology Source Type: research

Successful Removal of Gallbladder Stones Under Direct Visualization of Single-Operator Peroral Cholangioscopy (with Video)
(Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - March 2, 2024 Category: Gastroenterology Source Type: research

Electroacupuncture Improving Intestinal Barrier Function in Rats with Irritable Bowel Syndrome Through Regulating Aquaporins
ConclusionEA has an inhibitory effect on the NF- κB signaling pathway, and regulates the proteins of AQP1, AQP3, AQP8, and TJs to restore the balance of water metabolism and intestinal permeability in IBS-D, which also restored the function of the intestinal mucosa by regulating the intestinal flora.Graphical AbstractIrritable bowel syndrome with predominant diarrhea (IBS-D) is a common gastrointestinal disease in clinical practice, which was affected by intestinal mucosal barrier dysfunction, intestinal mucosal inflammation production and abnormal intestinal flora, then there is currently no specific drug for treating IB...
Source: Digestive Diseases and Sciences - February 29, 2024 Category: Gastroenterology Source Type: research

Upadacitinib as Rescue Therapy for the Treatment of Acute Severe Colitis in an Acute Care Setting
ConclusionUpadacitinib may be effective salvage therapy for acute severe colitis, but larger controlled trials are required to validate these results. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - February 28, 2024 Category: Gastroenterology Source Type: research

Pediatric ERCP: Evolving into an Outpatient Procedure
ConclusionWe analyzed outpatient and inpatient pediatric ERCP patient demographics and ERCP characteristics to identify factors that guide decision to determine whether pediatric ERCPs are performed on an outpatient vs. inpatient basis. There was no significant difference in adverse events associated with outpatient vs. inpatient pediatric ERCPs, attesting to the safety of outpatient ERCP for this subset of patients in the studied context. This is an area worthy of future prospective and multi-center study. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - February 28, 2024 Category: Gastroenterology Source Type: research

Cold Snare Polypectomy With or Without Submucosal Injection for Endoscopic Resection of Colorectal Polyps: A Meta-Analysis of Randomized Controlled Trials
ConclusionsSI-CSP is not an optimal substitute for CSP in the resection of colorectal polyps, particularly diminutive and small polyps. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - February 28, 2024 Category: Gastroenterology Source Type: research

Amiodarone and Dronedarone Causes Liver Injury with Distinctly Different Clinical Presentations
ConclusionAmiodarone hepatotoxicity resembles that seen in alcohol related liver injury, with fatty infiltration and inflammation. Dronedarone is less predictable, typically without fat and with a shorter latency of use before presentation. These differences may be explained, in part, by the differing pharmacokinetics of the two drugs leading to different mechanisms of hepatotoxicity. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - February 28, 2024 Category: Gastroenterology Source Type: research

Nomogram for Predicting the Risk of Complications after Endoscopic Foreign Body Removal from the Adult Upper Gastrointestinal Tract
ConclusionsOlder patients who ingested bones or jujube pits with more pressure points exerted on the digestive tract wall more than 24  h earlier should be considered most at risk of major complications after endoscopic removal of foreign bodies. The nomogram established in this study can be conveniently used to assess patients and develop treatment plans for the management of foreign body ingestion. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - February 28, 2024 Category: Gastroenterology Source Type: research

Are You In or Out?: The Trend Towards Outpatient Pediatric ERCP
(Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - February 28, 2024 Category: Gastroenterology Source Type: research

Endoscopic Ultrasound-Guided Pancreatic Pseudocyst Drainage Using a Novel Dilation Device with Double Guidewire Insertion Function (with Video)
(Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - February 28, 2024 Category: Gastroenterology Source Type: research