Added Value of 13C Analysis in Breath Tests in H2-Negative Subjects to Diagnose Lactose Malabsorption: A Proof of Concept Study
ConclusionsIn individuals with genetically demonstrated lactase non-persistence and negative hydrogen breath test, the use of13C-lactose with measurement of13CO2 excretion and hydrogen is a well-performing test to detect the lactose malabsorption and performs better than methane in our cohort. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - March 18, 2024 Category: Gastroenterology Source Type: research
“It’s Not a Gas”: The Future of Testing for Lactose Intolerance
Graphical Abstract (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - March 18, 2024 Category: Gastroenterology Source Type: research
Endoscopic Ultrasound in Non-healing Gastric Ulcer
(Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - March 18, 2024 Category: Gastroenterology Source Type: research
Endoscopic Ultrasound-Guided Pelvic Abscess Drainage: A Successful Minimally Invasive Approach
(Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - March 18, 2024 Category: Gastroenterology Source Type: research
Low-Dose Aspirin Use Does Not Increase Disease Activity in Pregnant Patients with Inflammatory Bowel Disease
ConclusionLDA use for preeclampsia prevention did not increase the incidence of disease activity in pregnant patients with IBD. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - March 16, 2024 Category: Gastroenterology Source Type: research
Effect of Suboptimal Disease Control on Patient Quality of Life: Real-World Data from the Observational IBD-PODCAST Canada Trial
ConclusionsApproximately 50% (CD) and 40% (UC) of patients from real-world Canadian practices had suboptimal disease control based on STRIDE-II criteria. Suboptimal control was underestimated by patients and clinicians and accompanied by reduced QoL, suggesting further efforts to implement STRIDE-II treat-to-target strategies are needed. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - March 16, 2024 Category: Gastroenterology Source Type: research
Low-Dose Aspirin Use Does Not Increase Disease Activity in Pregnant Patients with Inflammatory Bowel Disease
ConclusionLDA use for preeclampsia prevention did not increase the incidence of disease activity in pregnant patients with IBD. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - March 16, 2024 Category: Gastroenterology Source Type: research
Effect of Suboptimal Disease Control on Patient Quality of Life: Real-World Data from the Observational IBD-PODCAST Canada Trial
ConclusionsApproximately 50% (CD) and 40% (UC) of patients from real-world Canadian practices had suboptimal disease control based on STRIDE-II criteria. Suboptimal control was underestimated by patients and clinicians and accompanied by reduced QoL, suggesting further efforts to implement STRIDE-II treat-to-target strategies are needed. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - March 16, 2024 Category: Gastroenterology Source Type: research
Comparative Analysis of Enbloc or Piecemeal Removal After Enbloc Resection of Gastrointestinal Stromal Tumors
ConclusionEndoscopic piecemeal removal after en block resection of gastric GIST is safe and effective and achieves similar clinical outcomes as complete removal after en block resection. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - March 14, 2024 Category: Gastroenterology Source Type: research
Assessment of the Learning Curve for a Single-Use Disposable Duodenoscope
ConclusionAmong experienced pancreaticobiliary endoscopists, approximately 10 ERCPs is the threshold whereby procedure-related factors including cannulation success and procedural time improves. Procedure-related adverse events are consistent with those expected with reusable duodenoscopes. The need to cross-over from single-use duodenoscope to reusable duodenoscope did not appear to be related to the learning curve, as they were evenly distributed across the study period. These results can be used to guide adoption of single-use duodenoscopes into clinical practice. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - March 11, 2024 Category: Gastroenterology Source Type: research
Hospital-Level Care at Home for Patients with Cirrhosis
ConclusionsIn this two-site study, HH was feasible for patients with cirrhosis, holding promise as a hepatology delivery model. Future randomized trials are needed to further evaluate the efficacy of HH for patients with cirrhosis. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - March 11, 2024 Category: Gastroenterology Source Type: research
Like a Rolling (Gall)Stone: Optimal Treatment of Gallstone Obstruction of the Sigmoid Colon
ConclusionA multidisciplinary discussion between endoscopists and surgeons is often needed to choose the best therapeutic option, especially in high-risk patients. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - March 11, 2024 Category: Gastroenterology Source Type: research
Interleukin-22 Alleviates Caerulein-Induced Acute Pancreatitis by Activating AKT/mTOR Pathway
ConclusionThis study suggests that Interleukin -22 administration could alleviate pancreatic damage in caerulein-induced acute pancreatitis. This effect may result from the activation of the AKT/mTOR pathway, leading to the inhibition of autophagy. Consequently, Interleukin -22 shows potential as a treatment. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - March 11, 2024 Category: Gastroenterology Source Type: research
Impact of COVID-19 Treatment on Real-World Outcomes in Inflammatory Bowel Disease
ConclusionsPatients with IBD on advanced therapies were frequently treated for acute COVID-19. Although COVID-19 treatment was associated with temporary withholding of IBD therapy, it did not result in increased IBD flares. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - March 11, 2024 Category: Gastroenterology Source Type: research
