Highly Expressed Z-DNA Binding Protein 1 in Esophageal Cancer Promotes Tumor Growth
ConclusionThis research proves that downregulation of ZBP1 can inhibit the progression of ESCA. This finding indicates that ZBP1 may be a novel biomarker to improve the diagnosis and treatment of ESCA.Graphical Abstract (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - March 20, 2024 Category: Gastroenterology Source Type: research

Implementation and Analysis of a 5-Year Online Esophageal Motility Curriculum for Gastroenterology Fellows
ConclusionAn online, technology-based curriculum was effective in educating GI fellows on core competencies of EM. Fellows demonstrated improvement in proficiency of clinically important EM studies and increased comfort in interpreting EM studies. Further studies are needed to evaluate the use of technology-based learning to widely disseminate a structured training curriculum in EM, particularly in training programs without a motility presence. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - March 20, 2024 Category: Gastroenterology Source Type: research

Precutting Endoscopic Band Ligation-Assisted Resection Is Safe and Effective for Treating Gastric Submucosal Tumors from the Muscularis Propria
ConclusionPrecutting endoscopic band ligation-assisted resection is a safe, effective, and time-saving endoscopic technique for managing gastric small gastric submucosal tumors originating from the muscularis propria for both diagnosis and eradication.Graphical Abstract (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - March 20, 2024 Category: Gastroenterology Source Type: research

Some Drugs Have Two Faces: Paradoxical Colitis in a Patient with Psoriatic Arthritis Previously Treated with Etanercept and IL-17 Inhibitors
In this report, we w ill discuss the importance of considering paradoxical colitis in the differential diagnosis for patients even several years after TNF-α/IL-17 inhibitor initiation and explain why careful consideration must be made when initiating these colitis-inducing agents to treat patients with inflammatory dis orders. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - March 19, 2024 Category: Gastroenterology Source Type: research

A Rare Cause of Upper Gastrointestinal Bleeding
(Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - March 19, 2024 Category: Gastroenterology Source Type: research

Some Drugs Have Two Faces: Paradoxical Colitis in a Patient with Psoriatic Arthritis Previously Treated with Etanercept and IL-17 Inhibitors
In this report, we w ill discuss the importance of considering paradoxical colitis in the differential diagnosis for patients even several years after TNF-α/IL-17 inhibitor initiation and explain why careful consideration must be made when initiating these colitis-inducing agents to treat patients with inflammatory dis orders. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - March 19, 2024 Category: Gastroenterology Source Type: research

A Rare Cause of Upper Gastrointestinal Bleeding
(Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - March 19, 2024 Category: Gastroenterology Source Type: research

Development of Clinical Algorithm Utilizing Vibration-Controlled Transient Elastography to Detect Advanced Hepatic Fibrosis in Liver Transplant Recipients
ConclusionThe proposed clinical sequential covering analysis allows for better risk stratification when evaluating for advanced fibrosis in LT recipients compared to LSM alone. Additional efforts are necessary to further reduce the number of patients with indeterminate results in whom a liver biopsy may be required. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - March 18, 2024 Category: Gastroenterology Source Type: research

Comparative Efficacy of Subcutaneous and Intravenous Infliximab and Vedolizumab for Maintenance Treatment of TNF-naive Adult Patients with Inflammatory Bowel Disease: A Systematic Literature Review and Network Meta-analysis
ConclusionsSubcutaneous infliximab showed a favorable efficacy profile for achieving clinical remission and endoscopic outcomes during maintenance treatment in CD or UC.Graphical Abstract (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - March 18, 2024 Category: Gastroenterology Source Type: research

Added Value of 13C Analysis in Breath Tests in H2-Negative Subjects to Diagnose Lactose Malabsorption: A Proof of Concept Study
ConclusionsIn individuals with genetically demonstrated lactase non-persistence and negative hydrogen breath test, the use of13C-lactose with measurement of13CO2 excretion and hydrogen is a well-performing test to detect the lactose malabsorption and performs better than methane in our cohort. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - March 18, 2024 Category: Gastroenterology Source Type: research

“It’s Not a Gas”: The Future of Testing for Lactose Intolerance
Graphical Abstract (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - March 18, 2024 Category: Gastroenterology Source Type: research

Endoscopic Ultrasound in Non-healing Gastric Ulcer
(Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - March 18, 2024 Category: Gastroenterology Source Type: research

Endoscopic Ultrasound-Guided Pelvic Abscess Drainage: A Successful Minimally Invasive Approach
(Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - March 18, 2024 Category: Gastroenterology Source Type: research

Development of Clinical Algorithm Utilizing Vibration-Controlled Transient Elastography to Detect Advanced Hepatic Fibrosis in Liver Transplant Recipients
ConclusionThe proposed clinical sequential covering analysis allows for better risk stratification when evaluating for advanced fibrosis in LT recipients compared to LSM alone. Additional efforts are necessary to further reduce the number of patients with indeterminate results in whom a liver biopsy may be required. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - March 18, 2024 Category: Gastroenterology Source Type: research

Comparative Efficacy of Subcutaneous and Intravenous Infliximab and Vedolizumab for Maintenance Treatment of TNF-naive Adult Patients with Inflammatory Bowel Disease: A Systematic Literature Review and Network Meta-analysis
ConclusionsSubcutaneous infliximab showed a favorable efficacy profile for achieving clinical remission and endoscopic outcomes during maintenance treatment in CD or UC.Graphical Abstract (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - March 18, 2024 Category: Gastroenterology Source Type: research