Gastroesophageal Reflux Disease Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Design, synthesis, α-amylase and glucose diffusion inhibition, and molecular docking studies of new indenopyrazolones bearing benzothiazole derivatives
Bioorg Med Chem Lett. 2024 Mar 5:129692. doi: 10.1016/j.bmcl.2024.129692. Online ahead of print.ABSTRACTAn eco-friendly facile synthesis of a series of twenty 1-(4/6-substitutedbenzo[d]thiazol-2-yl)-3-(phenyl/substitutedphenyl)indeno[1,2-c]pyrazol-4(1H)-ones 7a-t was achieved by the reaction of 2-(benzoyl/substitutedbenzoyl)-(1H)-indene-1,3(2H)-dione 3a-t and 2-hydrazinyl-4/6-substitutedbenzo[d]thiazole 6a-t in presence of freshly dried ethanol and glacial acetic acid under reflux conditions in good yields. The newly synthesized derivatives were well characterized using different physical and spectral techniques (FTIR, 1H ...
Source: Bioorganic and Medicinal Chemistry Letters - March 7, 2024 Category: Chemistry Authors: Ravinder Punia Satbir Mor Suchita Sindhu Deepak Kumar Priyanku Pradip Das Deepak Kumar Jindal Ashwani Kumar Rajni Mohil Komal Jakhar Source Type: research

Design, synthesis, α-amylase and glucose diffusion inhibition, and molecular docking studies of new indenopyrazolones bearing benzothiazole derivatives
Bioorg Med Chem Lett. 2024 Mar 5;103:129692. doi: 10.1016/j.bmcl.2024.129692. Online ahead of print.ABSTRACTAn eco-friendly facile synthesis of a series of twenty 1-(4/6-substitutedbenzo[d]thiazol-2-yl)-3-(phenyl/substitutedphenyl)indeno[1,2-c]pyrazol-4(1H)-ones 7a-t was achieved by the reaction of 2-(benzoyl/substitutedbenzoyl)-(1H)-indene-1,3(2H)-dione 3a-t and 2-hydrazinyl-4/6-substitutedbenzo[d]thiazole 6a-t in presence of freshly dried ethanol and glacial acetic acid under reflux conditions in good yields. The newly synthesized derivatives were well characterized using different physical and spectral techniques (FTIR,...
Source: Bioorganic and Medicinal Chemistry Letters - March 7, 2024 Category: Chemistry Authors: Ravinder Punia Satbir Mor Suchita Sindhu Deepak Kumar Priyanku Pradip Das Deepak Kumar Jindal Ashwani Kumar Rajni Mohil Komal Jakhar Source Type: research

10-year follow-up results of the European Achalasia Trial: a multicentre randomised controlled trial comparing pneumatic dilation with laparoscopic Heller myotomy
Conclusions PD and LHM are equally effective even after 10 years of follow-up with limited risk to develop gastro-oesophageal reflux. Based on these data, we conclude that PD and LHM can both be proposed as initial treatment of achalasia. (Source: Gut)
Source: Gut - March 7, 2024 Category: Gastroenterology Authors: Boeckxstaens, G., Elsen, S., Belmans, A., Annese, V., Bredenoord, A. J., Busch, O. R., Costantini, M., Fumagalli, U., Smout, A. J. P. M., Tack, J., Vanuytsel, T., Zaninotto, G., Salvador, R. Tags: Gut Oesophagus Source Type: research

A Mendelian randomization analysis identifies causal association between sarcopenia and gastroesophageal reflux disease
In conclusion, this MR analysis supported the causal association between sarcopenia-related traits and GERD.PMID:38446595 | DOI:10.18632/aging.205627 (Source: Aging)
Source: Aging - March 6, 2024 Category: Biomedical Science Authors: Renwang Hu Can Liu Dan Li Source Type: research

Are night-time respiratory symptoms assessed by asthma control test affected by comorbidities?
CONCLUSIONS: These results confirm and extend previous findings showing that there is a higher likelihood that underlying unknown sleep disturbances worsen asthma control, suggesting that a more comprehensive assessment is necessary to clarify the cause of nocturnal symptoms in asthma.PMID:38446620 | DOI:10.1080/02770903.2024.2327036 (Source: Journal of Asthma)
Source: Journal of Asthma - March 6, 2024 Category: Respiratory Medicine Authors: Alida Benfante Alessandra Tomasello Chiara Caponetto Salvatore Battaglia Nicola Scichilone Source Type: research

Are nighttime respiratory symptoms assessed by asthma control test affected by comorbidities?
CONCLUSIONS: These results confirm and extend previous findings showing that there is a higher likelihood that underlying unknown sleep disturbances worsen asthma control, suggesting that a more comprehensive assessment is necessary to clarify the cause of nocturnal symptoms in asthma.PMID:38446620 | DOI:10.1080/02770903.2024.2327036 (Source: Journal of Asthma)
Source: Journal of Asthma - March 6, 2024 Category: Respiratory Medicine Authors: Alida Benfante Alessandra Tomasello Chiara Caponetto Salvatore Battaglia Nicola Scichilone Source Type: research

Short and long term effect of anti-reflux mucosectomy with cap-assisted endoscopic mucosal resection for refractory gastroesophageal disease
ConclusionARMS-C is a safe and effective endoscopic technique to treat refractory GERD patients. (Source: Surgical Endoscopy)
Source: Surgical Endoscopy - March 6, 2024 Category: Surgery Source Type: research

Outcomes of primary versus conversional Roux-En-Y gastric bypass after laparoscopic sleeve gastrectomy: a retrospective propensity score –matched cohort study
Conversional surgery is common after laparoscopic sleeve gastrectomy (LSG) because of suboptimal weight loss (SWL) or poor responders and gastroesophageal reflux disease (GERD). Roux-en-Y gastric bypass (RYGB)... (Source: BMC Surgery)
Source: BMC Surgery - March 6, 2024 Category: Surgery Authors: Mohamed Hany, Bart Torensma, Ahmed Zidan, Mohamed Ibrahim, Anwar Ashraf Abouelnasr, Ann Samy Shafiq Agayby and Iman El Sayed Tags: Research Source Type: research

A Case of Refractory Gastroesophageal Reflux Disease Successfully Treated with Endoscopic Anti-gastroesophageal Reflux Mucosal Resection by the ESD-G Method (with video)
Intern Med. 2024 Mar 4. doi: 10.2169/internalmedicine.3305-23. Online ahead of print.ABSTRACTA 70-year-old man who had undergone treatment for gastroesophageal reflux disease (GERD) by a family doctor presented to our hospital with severe heartburn and dysphagia despite taking vonoprazan (20 mg) for 3 months. A diagnosis of vonoprazan-refractory nonerosive reflux disease was made based on esophagogastroduodenoscopy and esophageal function examinations. The patient elected to undergo endoscopic treatment for GERD. Therefore, we performed endoscopic treatment using the endoscopic submucosal dissection (ESD-G) technique devel...
Source: Internal Medicine - March 3, 2024 Category: Internal Medicine Authors: Shun Sasaki Kazuhiro Ota Taro Iwatsubo Noriaki Sugawara Akitoshi Hakoda Hironori Tanaka Yosuke Mori Toshihisa Takeuchi Kazuhide Higuchi Hiroki Nishikawa Source Type: research