Topic highlight on texture and color enhancement imaging in gastrointestinal diseases
In conclusion, TXI can improve gastrointestinal lesion detection and qualitative diagnosis. Therefore, further studies on the efficacy of TXI in clinical practice are required.PMID:38681121 | PMC:PMC11045492 | DOI:10.3748/wjg.v30.i14.1934 (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - April 29, 2024 Category: Gastroenterology Authors: Osamu Toyoshima Toshihiro Nishizawa Keisuke Hata Source Type: research
Correlation between Pain and Anal Defecation Function in Postoperative Patients with Colorectal Cancer and Related Factors Affecting Patients' Prognosis
CONCLUSION: LARS is strongly associated with the patient's pain level, and factors such as anastomotic position <5 cm from the anal verge, preoperative radiotherapy, anastomotic fistula, high VAS level, and low MTV level will increase the risk of concurrent LARS in patients.PMID:38684502 | DOI:10.62713/aic.3173 (Source: Annali Italiani di Chirurgia)
Source: Annali Italiani di Chirurgia - April 29, 2024 Category: Surgery Authors: Yuanwei Zhang Chengjiang Xiang Jinhao Liang Source Type: research
Implications of Pretreatment Serum Carcinoembryonic Antigen Levels and Perineural Invasion with Staging, Prognosis, and Management in Stage I-III Colon Cancer after Surgery: A Retrospective Cohort Study in the SEER Database
CONCLUSION: For postoperative patients with stage I-III colon cancer, our study indicated that the CP stage is a significant prognostic factor for CSS, which deserves more clinical attention. It's worth noting that including the CP stage in the AJCC TNM staging system of colon carcinoma is beneficial to the survival prediction and clinical treatment.PMID:38684496 | DOI:10.62713/aic.3296 (Source: Annali Italiani di Chirurgia)
Source: Annali Italiani di Chirurgia - April 29, 2024 Category: Surgery Authors: Qing Zhang Li Wang Ruirui Sun Jian Gao Tingting Liu Source Type: research
OSW-1 triggers necroptosis in colorectal cancer cells through the RIPK1/RIPK3/MLKL signaling pathway facilitated by the RIPK1-p62/SQSTM1 complex
CONCLUSION: We propose that OSW-1 can induce necroptosis through the RIPK1/RIPK3/MLKL signaling pathway, and that this effect is mediated by the RIPK1-p62/SQSTM1 complex, in CRC cells. These results provide a theoretical foundation for the use of OSW-1 in the clinical treatment of CRC.PMID:38681991 | PMC:PMC11045482 | DOI:10.3748/wjg.v30.i15.2155 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - April 29, 2024 Category: Gastroenterology Authors: Nan Wang Chao-Yang Li Teng-Fei Yao Xiao-Dan Kang Hui-Shu Guo Source Type: research
< em > Fusobacterium nucleatum < /em > -induced imbalance in microbiome-derived butyric acid levels promotes the occurrence and development of colorectal cancer
CONCLUSION: F. nucleatum can promote cancer progression through its inhibitory effect on butyric acid, via the AMPK signaling pathway.PMID:38681125 | PMC:PMC11045493 | DOI:10.3748/wjg.v30.i14.2018 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - April 29, 2024 Category: Gastroenterology Authors: Qi-Long Wu Xiao-Ting Fang Xin-Xin Wan Qing-Yong Ding Yan-Jun Zhang Ling Ji Yong-Liang Lou Xiang Li Source Type: research
Topic highlight on texture and color enhancement imaging in gastrointestinal diseases
In conclusion, TXI can improve gastrointestinal lesion detection and qualitative diagnosis. Therefore, further studies on the efficacy of TXI in clinical practice are required.PMID:38681121 | PMC:PMC11045492 | DOI:10.3748/wjg.v30.i14.1934 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - April 29, 2024 Category: Gastroenterology Authors: Osamu Toyoshima Toshihiro Nishizawa Keisuke Hata Source Type: research
Critical updates in neuroendocrine tumors: Version 9 American Joint Committee on Cancer staging system for gastroenteropancreatic neuroendocrine tumors
CA Cancer J Clin. 2024 Apr 29. doi: 10.3322/caac.21840. Online ahead of print.ABSTRACTThe American Joint Committee on Cancer (AJCC) staging system for all cancer sites, including gastroenteropancreatic neuroendocrine tumors (GEP-NETs), is meant to be dynamic, requiring periodic updates to optimize AJCC staging definitions. This entails the collaboration of experts charged with evaluating new evidence that supports changes to each staging system. GEP-NETs are the second most prevalent neoplasm of gastrointestinal origin after colorectal cancer. Since publication of the AJCC eighth edition, the World Health Organization has ...
Source: Clinical Colorectal Cancer - April 29, 2024 Category: Cancer & Oncology Authors: Aman Chauhan Kelley Chan Thorvardur R Halfdanarson Andrew M Bellizzi Guido Rindi Dermot O'Toole Phillip S Ge Dhanpat Jain Arvind Dasari Daniel A Anaya Emily Bergsland Erik Mittra Alice C Wei Thomas A Hope Ayse T Kendi Samantha M Thomas Sherlonda Flem Jame Source Type: research
Emergency Department Use in Adolescent and Young Adult Cancer Early Survivors from 2006 to 2020
Conclusion: ED utilization declined as time from diagnosis elapsed, but higher utilization was associated with social determinants of health and cancer types.PMID:38682323 | DOI:10.1089/jayao.2023.0174 (Source: Ann Oncol)
Source: Ann Oncol - April 29, 2024 Category: Cancer & Oncology Authors: Karen J Wernli Eric C Haupt Neetu Chawla Thearis Osuji Ernest Shen Andrew B Smitherman Mallory Casperson Anne C Kirchhoff Bradley J Zebrack Theresa H M Keegan Lawrence Kushi Christopher Baggett Heydon K Kaddas Kathryn J Ruddy Candice A M Sauder Theodore W Source Type: research
The Role of Delirium on Short- and Long-Term Postoperative Outcomes Following Major Gastrointestinal Surgery for Cancer
CONCLUSIONS: Postoperative delirium occurred in one in 50 patients undergoing surgical resection of a digestive tract cancer. Delirium was linked to a reduced likelihood of achieving an optimal postoperative outcome, increased ICU utilization, higher expenditures, and a worse long-term prognosis. Initiatives to prevent delirium are vital to improve postoperative outcomes among cancer surgery patients.PMID:38683304 | DOI:10.1245/s10434-024-15358-x (Source: Ann Oncol)
Source: Ann Oncol - April 29, 2024 Category: Cancer & Oncology Authors: Erryk S Katayama Hunter Stecko Selamawit Woldesenbet Mujtaba Khalil Muhammad Musaab Munir Yutaka Endo Diamantis Tsilimigras Timothy M Pawlik Source Type: research
Evaluation of the Combined Effect of Caffeine and 5-Fluorouracil on Colorectal Cancer Cell Lines
In this study, initially HCT116 and HEK293 cell lines were cultured as cancer and normal cells, respectively. These cell lines were then evaluated for cytotoxicity, induction of apoptosis, and rate of cell migration. All data were analyzed by statistical methods.RESULTS: The results indicated that a combination of caffeine and 5-FU augmented their cytotoxicity in HCT116 cells but reduced cytotoxicity in HEK293 cells. No reduction was observed in the migration of HCT116 cells that were treated with caffeine or a combination of caffeine and 5-FU. Also, it seems that caffeine reverses the apoptotic effect of 5-FU in HCT116 ce...
Source: Asian Pacific Journal of Cancer Prevention - April 29, 2024 Category: Cancer & Oncology Authors: Fatemeh Khavari Mohammad Taheri Hamed Manoochehri Pejman Molaei Fatemeh Nouri Source Type: research
LncRNA ANRIL Promotes Glucose Metabolism and Proliferation of Colon Cancer in a High-Glucose Environment and is Associated with Worse Outcome in Diabetic Colon Cancer Patients
CONCLUSIONS: A high-glucose environment can increase the tumor-promoting effect of ANRIL. ANRIL can promote glucose metabolism and colon cancer proliferation by downregulating miR-186-5p with subsequent upregulation of glycolysis enzymes expression and inhibition of apoptosis.PMID:38679999 | DOI:10.31557/APJCP.2024.25.4.1371 (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - April 29, 2024 Category: Cancer & Oncology Authors: Hala Mosaad Sally M Shalaby Nevertety M Mahmoud Mona M Ahmed Alaa Fayed Hassan R Ashour Walaa Sarhan Source Type: research
Hopelessness and Social Support among Cancer Patients in Saudi Arabia
CONCLUSION: The findings of the present study suggest that the levels of hopelessness in cancer patients are moderate, and the levels of social support received by participants are high. In addition, the relationship between the levels of hopelessness and the levels of social support received is inversely proportional.PMID:38679998 | DOI:10.31557/APJCP.2024.25.4.1363 (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - April 29, 2024 Category: Cancer & Oncology Authors: Hawazen Rawas Jennifer De Beer Osamah Alturki Mohammed Altorki Tareq Alhelali Anas Althagfi Nawaf Faisal Faisal Albalawi Muhammad Anwar Khan Source Type: research
M2 Macrophage Prominently Distributed in the Rat's Colon of DMH-Induced Inflammation Associated Colorectal Cancer
CONCLUSION: All of the rat's colon showing chronic inflammation that led to the tumorigenesis.PMID:38679997 | DOI:10.31557/APJCP.2024.25.4.1357 (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - April 29, 2024 Category: Cancer & Oncology Authors: Windy Arensya Omadhika Solikhah Solikhah Albertus Ari Adrianto Yekti Asih Purwestri Dewi Kartikawati Paramita Source Type: research
From Antioxidant to Anticancer is Vitamin C Effective in Colorectal Cancer?
Asian Pac J Cancer Prev. 2024 Apr 1;25(4):1107-1108. doi: 10.31557/APJCP.2024.25.4.1107.NO ABSTRACTPMID:38679968 | DOI:10.31557/APJCP.2024.25.4.1107 (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - April 29, 2024 Category: Cancer & Oncology Authors: Kanza Farhan Muhammad Burhan Tariq Ahmed Saddiq Mansha Mansoor Aliza Ahmed Abdul-Samed Mohammed Source Type: research
Baicalein triggers ferroptosis in colorectal cancer cells via blocking the JAK2/STAT3/GPX4 axis
This study demonstrates that ferroptosis contributes to baicalein-induced anti-CRC activity through blockade of the JAK2/STAT3/GPX4 signaling pathway, which provides evidence for the therapeutic application of baicalein against CRC.PMID:38684798 | DOI:10.1038/s41401-024-01258-z (Source: Acta Pharmacologica Sinica)
Source: Acta Pharmacologica Sinica - April 29, 2024 Category: Drugs & Pharmacology Authors: Jian-Qin Lai Le-le Zhao Chao Hong Qiu-Ming Zou Jin-Xuan Su Si-Jia Li Xiao-Feng Zhou Zi-Sheng Li Bo Deng Jie Cao Qi Qi Source Type: research
