Validation of the PediBIRN-7 clinical prediction rule for pediatric abusive head trauma
CONCLUSION: The PediBIRN-7's overall AHT prediction performance has been validated in a novel, equivalent, patient population. Its patient-specific estimates of AHT probability can inform physicians' AHT-related diagnostic reasoning after abuse evaluation.PMID:38663048 | DOI:10.1016/j.chiabu.2024.106799 (Source: Child Abuse and Neglect)
Source: Child Abuse and Neglect - April 25, 2024 Category: Child Development Authors: Kent P Hymel Christopher L Carroll Terra N Frazier Kerri Weeks Bruce E Herman Mark Marinello Yiming Chen Ming Wang Stephen C Boos Pediatric Brain Injury Research Network (PediBIRN) Investigators Source Type: research

Past Is Prologue: Ethical Issues in Pediatric Psychedelics Research and Treatment
Perspect Biol Med. 2023;66(1):129-144. doi: 10.1353/pbm.2023.0007.ABSTRACTRecent clinical trials of psychedelic drugs aim to treat a range of psychiatric conditions in adults. MDMA and psilocybin administered with psychotherapy have received FDA designation as "breakthrough therapies" for post-traumatic stress disorder (PTSD) and treatment-resistant depression (TRD) respectively. Given the potential benefit for minors burdened with many of the same disorders, calls to expand experimentation to minors are inevitable. This essay examines psychedelic research conducted on children from 1959 to 1974, highlighting methodologica...
Source: Perspectives in Biology and Medicine - April 25, 2024 Category: Medical Ethics Authors: Gail A Edelsohn Dominic Sisti Source Type: research

Parents' Trigger Tool for Children with Medical Complexity - PAT-CMC: Development of a recognition tool for clinical deterioration at home
CONCLUSION: Priority indicators of clinical deterioration of CMC were identified and integrated into a validated trigger tool designed for parents or other lay caregivers at home, to recognize signs of acute severe illness and initiate healthcare interventions.IMPACT: The PAT-CMC was developed to guide families in recognizing signs of deterioration in CMC and has potential for initiating an early escalation of care. This tool may also be useful to support education provided by healthcare providers to families before hospital discharge.PATIENT OR PUBLIC CONTRIBUTION: Parents of CMC were directly involved in the selection of...
Source: Adv Data - April 25, 2024 Category: Epidemiology Authors: Catia Genna Kiara Ros Thekkan Caterina Geremia Michela Di Furia Corrado Cecchetti Emilia Rufini Michele Salata Daniela Perrotta Immacolata Dall'Oglio Emanuela Tiozzo Massimiliano Raponi Orsola Gawronski Source Type: research

Acoustic Analyses of Tone Productions in Sequencing Contexts Among Cantonese-Speaking Preschool Children With and Without Childhood Apraxia of Speech
CONCLUSIONS: This study demonstrated that Cantonese-speaking children with CAS had difficulty in varying F0 within syllables as compared to those without CAS, suggesting pitch variation difficulty and language-specific impairment profiles in CAS. Future investigations of objective measures for identifying Cantonese speakers with CAS and cross-linguistic investigations using growth curve analysis and the TST are suggested.PMID:38662942 | DOI:10.1044/2024_JSLHR-23-00383 (Source: Journal of speech, language, and hearing research : JSLHR)
Source: Journal of speech, language, and hearing research : JSLHR - April 25, 2024 Category: Speech-Language Pathology Authors: Eddy C H Wong Min Ney Wong Shelley L Velleman Source Type: research

Creating optimally safe and enjoyable youth sporting experiences within the United Kingdom
Psychol Sport Exerc. 2024 Apr 23:102652. doi: 10.1016/j.psychsport.2024.102652. Online ahead of print.ABSTRACTConsidering recent research and reports, much attention has been given to understanding and addressing issues of abuse in sport. Similarly, attention has been given to enhancing children's psychosocial experiences within sport. However, to-date, consideration of these two elements together, that is minimising abuse and enhancing enjoyment, has been minimal. Thus, the purpose of the current study was to explore perceptions of the process through which an optimally safe and enjoyable sporting experience can be create...
Source: Psychology of Sport and Exercise - April 25, 2024 Category: Sports Medicine Authors: Maita J Furusa Camilla J Knight Thomas D Love Source Type: research

Blood serum levels of PACAP and migraine onset: A systematic review and meta-analysis of observational studies
CONCLUSION: There is a very low certainty of evidence suggesting that the PACAP level is negatively correlated with migraine disease duration of adults with migraine and it varies greatly among different periods of migraine of both adults and children with migraine.PMID:38659322 | DOI:10.1111/head.14711 (Source: Headache)
Source: Headache - April 25, 2024 Category: Neurology Authors: Guoliang Zhu Miao Wang Fanyi Kong Source Type: research

Evaluation of Foot Structure in Preschool Children Based on Body Mass
CONCLUSIONS No correlation was observed between high BMI and the occurrence of anomalies in foot structure. A relationship was identified between muscle mass and foot structure.PMID:38659197 | DOI:10.12659/MSM.943765 (Source: Medical Science Monitor)
Source: Medical Science Monitor - April 25, 2024 Category: Research Authors: Aleksandra Kopaczy ńska Alicja Bober Agnieszka Puk Agnieszka Chwa łczyńska Source Type: research

Bayesian network-based survival prediction model for patients having undergone post-transjugular intrahepatic portosystemic shunt for portal hypertension
CONCLUSION: This study successfully developed a BN-based survival prediction model with good predictive capabilities. It offers valuable insights for treatment strategies and prognostic evaluations in patients having undergone TIPS surgery for PHT.PMID:38659484 | PMC:PMC11036496 | DOI:10.3748/wjg.v30.i13.1859 (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - April 25, 2024 Category: Gastroenterology Authors: Rong Chen Ling Luo Yun-Zhi Zhang Zhen Liu An-Lin Liu Yi-Wen Zhang Source Type: research

Radiological features and treatment of erupting maxillary canines in relation to the occurrence of dental developmental abnormalities
CONCLUSIONS: The children with dental developmental abnormalities more often showed evidence of early treatment for the canines. Monitoring of the erupting canines after the first mixed stage is important to enable timely early treatment.PMID:38661111 | DOI:10.2340/aos.v83.40488 (Source: Acta Odontologica Scandinavica)
Source: Acta Odontologica Scandinavica - April 25, 2024 Category: Dentistry Authors: Jenni Ristaniemi Terhi Karjalainen Kati Kujasalo Wille Rajala Paula Pesonen Raija L ähdesmäki Source Type: research

Electrical Stimulation of Acupuncture Points Helps Resolve a Child's Failure to Thrive
CONCLUSIONS: In this particular case, electroacupuncture (EA) stimulation may have facilitated a weight gain in this female child. EA (nonneedle) research should be explored for FTT.PMID:38659723 | PMC:PMC11036154 | DOI:10.1089/acu.2023.0087 (Source: Acupuncture in Medicine)
Source: Acupuncture in Medicine - April 25, 2024 Category: Complementary Medicine Authors: Erik K Koda Source Type: research

Bayesian network-based survival prediction model for patients having undergone post-transjugular intrahepatic portosystemic shunt for portal hypertension
CONCLUSION: This study successfully developed a BN-based survival prediction model with good predictive capabilities. It offers valuable insights for treatment strategies and prognostic evaluations in patients having undergone TIPS surgery for PHT.PMID:38659484 | PMC:PMC11036496 | DOI:10.3748/wjg.v30.i13.1859 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - April 25, 2024 Category: Gastroenterology Authors: Rong Chen Ling Luo Yun-Zhi Zhang Zhen Liu An-Lin Liu Yi-Wen Zhang Source Type: research

TFEB regulates dendritic cell antigen presentation to modulate immune balance in asthma
CONCLUSION: TFEB might have a vital role in asthma's development by impacting the antigen presentation of DCs, regulating T cell subgroup differentiation, and influencing cytokine secretion. Its involvement could be pivotal in rebalancing the immune system in asthma. These research findings could potentially unveil novel therapeutic avenues for treating asthma.PMID:38664707 | DOI:10.1186/s12931-024-02806-1 (Source: Cell Research)
Source: Cell Research - April 25, 2024 Category: Cytology Authors: JinYing Xiang Bo Liu Yan Li Yinying Ren Yuehan Li Mi Zhou Jinyue Yu Zhengxiu Luo Enmei Liu Zhou Fu Fengxia Ding Source Type: research

Preparing to "Live a Life of Possibilities": Experiences of Healthcare Providers Readying Autistic Adolescents and Their Families for Independent Driving
This study describes providers' experiences supporting autistic adolescents and families in the decision to pursue licensure and identifies barriers experienced in providing support. We conducted interviews with 15 healthcare providers focused on how they support autistic adolescents and their families in navigating topics related to independence, driving, and transportation. Key themes identified included: importance of understanding adolescents' perspectives and motivations, approaches to readying caregivers for children to pursue driving, and role of providers in fostering agreement between adolescents and caregivers. R...
Source: Journal of Autism and Developmental Disorders - April 25, 2024 Category: Psychiatry Authors: Rachel K Myers Christina Labows Catherine C McDonald Benjamin E Yerys Emma B Sartin Meghan E Carey Cynthia J Mollen Allison E Curry Source Type: research

Measuring Dispositional Empathy in South African Children
CONCLUSION: This is the first psychometric evaluation of the QCAE as a parent-report measure, and our results indicate that it should prove useful for future assessments of dispositional empathy in children across a variety of contexts.PMID:38659217 | DOI:10.1017/neu.2024.19 (Source: Acta Neuropsychiatrica)
Source: Acta Neuropsychiatrica - April 25, 2024 Category: Psychiatry Authors: Susan Malcolm-Smith Lea-Ann Pileggi Raphaella Lewis Source Type: research

Chinese Grammatical Development of Deaf and Hard of Hearing Children in a Sign Bilingualism and Coenrollment Program
Am Ann Deaf. 2023;167(5):675-699. doi: 10.1353/aad.2023.0007.ABSTRACTThe literacy development of d/Deaf and hard of hearing (d/Dhh) children has always been a matter of grave concern among educators, and grammatical knowledge is said to constitute a major component such development. The present article reports on a study that examined the development of Chinese grammar among groups of d/Dhh and hearing children who received education through a sign bilingualism and coenrollment (SLCO) approach. Findings from administration of a prestandardized assessment tool showed that while the d/Dhh children generally lagged behind the...
Source: American Annals of the Deaf - April 25, 2024 Category: Audiology Authors: Gladys Tang Qun Li Jia Li Chris K-M Yiu Source Type: research