Cognitive and social adaptation in autism spectrum disorder: A prospective cohort study
CONCLUSION: Logic mathematics and memory promote better social insertion in children with autism spectrum disorder. General cognitive ability promotes communication.PMID:38655981 | DOI:10.1590/1516-3180.2023.0184.R1.16022024 (Source: Sao Paulo Medical Journal)
Source: Sao Paulo Medical Journal - April 24, 2024 Category: General Medicine Authors: M árcia Regina Fumagalli Marteleto Jacy Perissinoto Source Type: research

Prenatal exposure to valproic acid reduces synaptic δ-catenin levels and disrupts ultrasonic vocalization in neonates
Neuropharmacology. 2024 Apr 23;253:109963. doi: 10.1016/j.neuropharm.2024.109963. Online ahead of print.ABSTRACTValproic acid (VPA) is an effective and commonly prescribed drug for epilepsy and bipolar disorder. However, children born from mothers treated with VPA during pregnancy exhibit an increased incidence of autism spectrum disorder (ASD). Although VPA may impair brain development at the cellular level, the mechanism of VPA-induced ASD has not been completely addressed. A previous study has found that VPA treatment strongly reduces δ-catenin mRNA levels in cultured human neurons. δ-catenin is important for the cont...
Source: Neuropharmacology - April 24, 2024 Category: Drugs & Pharmacology Authors: Seung Hyun Roh Hadassah Mendez-Vazquez Matheus F Sathler Michael J Doolittle Anastasiya Zaytseva Hannah Brown Morgan Sainsbury Seonil Kim Source Type: research

The clinical picture of bipolar affective disorders in children and adolescents hospitalized at the psychiatric ward in Sosnowiec
CONCLUSIONS: In the studied population of children and adolescents, BD usually started with a depression episode accompanied by a high rate of comorbid disorders and in most cases there was an original misdiagnosis. Study results also point to a significant frequency of some pathological symptoms in this population.PMID:38654505 | DOI:10.12740/PP/OnlineFirst/175719 (Source: Psychiatria Polska)
Source: Psychiatria Polska - April 24, 2024 Category: Psychiatry Authors: Lena Cicho ń Ma łgorzata Janas-Kozik El żbieta Chełmecka Krzysztof M Wilczy ński Ireneusz Jelonek Janusz K Rybakowski Source Type: research

Epidemiological and molecular surveillance of norovirus in the Brazilian Amazon: description of recombinant genotypes and improvement of evolutionary analysis
This study demonstrates that norovirus is a primary causative agent of gastroenteritis and provides data on viral genetic diversity that may facilitate infection surveillance and vaccine development.PMID:38656038 | PMC:PMC11027490 | DOI:10.1590/S1678-9946202466022 (Source: Revista do Instituto de Medicina Tropical de Sao Paulo)
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - April 24, 2024 Category: Tropical Medicine Authors: Jonaia Novaes da Costa Jones Anderson Monteiro Siqueira Dielle Monteiro Teixeira Patr ícia Dos Santos Lobo Sylvia de F átima Dos Santos Guerra Isadora Monteiro Souza Bruna Trindade Moreira Cardoso Luana Silva Soares Farias Hugo Reis Resque Yvone Benchim Source Type: research

Stressful life events and prenatal representations of the child
Attach Hum Dev. 2024 Apr 24:1-17. doi: 10.1080/14616734.2024.2345242. Online ahead of print.ABSTRACTCaregivers' mental representations of their children can be assessed prenatally and are prospectively associated with later caregiving quality and caregiver-child attachment. Compared to balanced, distorted or disengaged representations are linked to insecure caregiver-child attachments. The present study explored factors (i.e. stressful life experiences and positive experiences) that may be linked to risk for distorted and disengaged representations. We used a brief version of the Prenatal Working Model of the Child Intervi...
Source: Attachment and Human Development - April 24, 2024 Category: Child Development Authors: Lauren G Bailes Abigail Blum Whitney Barnett Hannah Piersiak Sydney Takemoto Brooke Fleming Caelan Alexander Kathryn L Humphreys Source Type: research

Improving connections to early childhood systems of care via a universal home visiting program in Massachusetts
Child Youth Serv Rev. 2023 Jul;150:10.1016/j.childyouth.2023.106995. doi: 10.1016/j.childyouth.2023.106995.ABSTRACTWelcome Family is a universal, short-term nurse home visiting program designed to promote optimal maternal and infant physical and mental well-being and provide an entry point into the early childhood system of care to all families with newborns up to 8 weeks old living in defined communities in Massachusetts. The present study examines whether: 1) Welcome Family meets its goal of successfully connecting families to two early childhood programs-evidence-based home visiting (EBHV) and early intervention (EI)-re...
Source: Children and Youth Services Review - April 24, 2024 Category: Child Development Authors: Chie Kotake Rebecca C Fauth Katie Stetler Jessica L Goldberg Christine F Silva Susan E Manning Source Type: research

Association of Breastfeeding Duration with Neurodevelopmental Outcomes in an Enriched Familial Likelihood Cohort for Autism Spectrum Disorder
This study aimed to compare the breastfeeding (BF) duration of the younger siblings of children with ASD in an enriched-likelihood cohort for autism spectrum disorder (ASD), and to determine whether longer BF duration was associated with differences in neurodevelopmental outcomes in this cohort. Information on BF practices was collected via surveys in the MARBLES (Markers of Autism Risk in Babies-Learning Early Signs) study. Developmental evaluations, including the Mullen Scales of Early Learning and the Autism Diagnostic Observation Schedule, were conducted by expert clinicians. Participants' neurodevelopmental outcome wa...
Source: Child Psychiatry and Human Development - April 24, 2024 Category: Child Development Authors: Ruchi Punatar Kathleen Angkustsiri Laura R Kair Daniel J Tancredi Danielle J Harvey Rebecca J Schmidt Source Type: research

A longitudinal study on the association between trait mindfulness and maternal bonding across the perinatal period
CONCLUSION: Mindfulness-based interventions may be helpful in supporting expectant mothers who are at risk for suboptimal bonding.PMID:38655861 | DOI:10.1080/02646838.2024.2342904 (Source: Journal of Reproductive and Infant Psychology)
Source: Journal of Reproductive and Infant Psychology - April 24, 2024 Category: Psychiatry & Psychology Authors: Myrthe G B M Boekhorst Noor de Waal Lisanne Smit Lianne P Hulsbosch Marion I van den Heuvel Inga Schwabe Victor Pop Ivan Nykl íček Source Type: research

Vaccines and monoclonal antibodies: new tools for malaria control
Clin Microbiol Rev. 2024 Apr 24:e0007123. doi: 10.1128/cmr.00071-23. Online ahead of print.ABSTRACTSUMMARYMalaria remains one of the biggest health problems in the world. While significant reductions in malaria morbidity and mortality had been achieved from 2000 to 2015, the favorable trend has stalled, rather significant increases in malaria cases are seen in multiple areas. In 2022, there were 249 million estimated cases, and 608,000 malaria-related deaths, mostly in infants and children aged under 5 years, globally. Therefore, in addition to the expansion of existing anti-malarial control measures, it is critical to dev...
Source: Clinical Microbiology Reviews - April 24, 2024 Category: Microbiology Authors: Kazutoyo Miura Yevel Flores-Garcia Carole A Long Fidel Zavala Source Type: research

Clinical Outcome and its Predictors in Children With Newly Diagnosed Immune Thrombocytopenia
CONCLUSION: The rate of chronicity and intracranial bleeding in our cohort is more than the reported rates in literature. Higher ALC was found to be associated with response.PMID:38655885 (Source: Indian Pediatrics)
Source: Indian Pediatrics - April 24, 2024 Category: Pediatrics Authors: Parameswary Singaravadivelu Jaikumar Govindaswamy Ramamoorthy C G Delhi Kumar Source Type: research

Spectrum of Genital and Extragenital Anomalies in Malformation Syndromes Associated With 46, XY Disorders of Sex Development: A Single Center Experience
CONCLUSION: Integration between clinical, laboratory and genetic data is the cornerstone in the management of XY DSD patients for appropriate decision making of surgical intervention and sex assignment, in addition to screening for other associated features of each mutation.PMID:38655886 (Source: Indian Pediatrics)
Source: Indian Pediatrics - April 24, 2024 Category: Pediatrics Authors: Shaymaa Raafat Yasmine Abdelmeguid Mostafa Kotb Ahmed Oshiba Source Type: research

Learning difficulties in school children: health and education professionals' perceptions
Rev Bras Enferm. 2024 Apr 22;77(1):e20230074. doi: 10.1590/0034-7167-2023-0074. eCollection 2024.ABSTRACTOBJECTIVES: to understand health and education professionals' perceptions regarding children's learning difficulties in public schools.METHODS: qualitative research, of the participatory action type, linked to Paulo Freire's Research Itinerary. Forty-five professionals participated, through interviews and a Virtual Culture Circle. The analysis was developed through careful reading, reflection and interpretation of highlighted topics.RESULTS: professionals discussed the (in)visibility of learning difficulties, strategies...
Source: Revista Brasileira de Enfermagem - April 24, 2024 Category: Nursing Authors: Pamela Camila Fernandes Rumor Michelle Kuntz Durand Jeane Barros de Souza Janaina Medeiros de Souza Adriana Bitencourt Magagnin Ivonete Teresinha Sch ülter Buss Heidemann Source Type: research

Cognitive and social adaptation in autism spectrum disorder: A prospective cohort study
CONCLUSION: Logic mathematics and memory promote better social insertion in children with autism spectrum disorder. General cognitive ability promotes communication.PMID:38655981 | DOI:10.1590/1516-3180.2023.0184.R1.16022024 (Source: Sao Paulo Medical Journal)
Source: Sao Paulo Medical Journal - April 24, 2024 Category: General Medicine Authors: M árcia Regina Fumagalli Marteleto Jacy Perissinoto Source Type: research

Prenatal exposure to valproic acid reduces synaptic δ-catenin levels and disrupts ultrasonic vocalization in neonates
Neuropharmacology. 2024 Apr 23;253:109963. doi: 10.1016/j.neuropharm.2024.109963. Online ahead of print.ABSTRACTValproic acid (VPA) is an effective and commonly prescribed drug for epilepsy and bipolar disorder. However, children born from mothers treated with VPA during pregnancy exhibit an increased incidence of autism spectrum disorder (ASD). Although VPA may impair brain development at the cellular level, the mechanism of VPA-induced ASD has not been completely addressed. A previous study has found that VPA treatment strongly reduces δ-catenin mRNA levels in cultured human neurons. δ-catenin is important for the cont...
Source: Neuropharmacology - April 24, 2024 Category: Drugs & Pharmacology Authors: Seung Hyun Roh Hadassah Mendez-Vazquez Matheus F Sathler Michael J Doolittle Anastasiya Zaytseva Hannah Brown Morgan Sainsbury Seonil Kim Source Type: research

The clinical picture of bipolar affective disorders in children and adolescents hospitalized at the psychiatric ward in Sosnowiec
CONCLUSIONS: In the studied population of children and adolescents, BD usually started with a depression episode accompanied by a high rate of comorbid disorders and in most cases there was an original misdiagnosis. Study results also point to a significant frequency of some pathological symptoms in this population.PMID:38654505 | DOI:10.12740/PP/OnlineFirst/175719 (Source: Psychiatria Polska)
Source: Psychiatria Polska - April 24, 2024 Category: Psychiatry Authors: Lena Cicho ń Ma łgorzata Janas-Kozik El żbieta Chełmecka Krzysztof M Wilczy ński Ireneusz Jelonek Janusz K Rybakowski Source Type: research