Advances in paediatrics in 2016: current practices and challenges in allergy, autoimmune diseases, cardiology, endocrinology, gastroenterology, infectious diseases, neonatology, nephrology, neurology, nutrition, pulmonology

AbstractThis review reports main progresses in various pediatric issues published in Italian Journal of Pediatrics and in international journals in 2016. New insights in clinical features or complications of several disorders may be useful for our better understanding. They comprise severe asthma, changing features of lupus erythematosus from birth to adolescence, celiac disease, functional gastrointestinal disorders, Moebius syndrome, recurrent pneumonia. Risk factors for congenital heart defects, Kawasaki disease have been widely investigated. New diagnostic tools are available for ascertaining brucellosis, celiac disease and viral infections. The usefulness of aCGH as first-tier test is confirmed in patients with neurodevelopmental disorders. Novel information have been provided on the safety of milk for infants. Recent advances in the treatment of common disorders, including neonatal respiratory distress syndrome, hypo-glycemia in newborns, atopic dermatitis, constipation, cyclic vomiting syndrome, nephrotic syndrome, diabetes mellitus, regurgitation, short stature, secretions in children with cerebral palsy have been reported. Antipyretics treatment has been updated by national guidelines and studies have excluded side effects (e.g. asthma risk during acetaminophen therapy). Vaccinations are a painful event and several options are reported to prevent this pain. Adverse effects due to metabolic abnormalities are reported for second generation antipsychotic drugs.
Source: Italian Journal of Pediatrics - Category: Pediatrics Source Type: research

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Do not Rx oral steroids for back pain.
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Pain Medicine Source Type: forums
Conclusions: Negative ICS beliefs are associated with higher number of oral steroid courses. The association between CAM endorsement and asthma control is varied, but mostly in favor of improved control. Financial difficulties may make CAM use more likely. PMID: 32646322 [PubMed - as supplied by publisher]
Source: Journal of Asthma - Category: Respiratory Medicine Tags: J Asthma Source Type: research
Authors: Dangat K, Khaire A, Joshi S Abstract During the period of lactation, there is extensive growth and development of the mammary gland in order to fulfil the increased demands of milk for the growing infant. Angiogenesis plays a key role in alveolar development and facilitates optimal milk production. Vascular endothelial growth factor (VEGF) is one of the key growth factors regulating angiogenesis in mammary gland. Apart from VEGF, neurotrophins are also known to regulate angiogenesis through direct or indirect mechanisms. Few studies have demonstrated mRNA levels of neurotrophins and their receptors in mamm...
Source: Growth Factors - Category: Research Tags: Growth Factors Source Type: research
CONCLUSIONS: HFNO provides a hands-free induction of general anaesthesia and yields adequate preoxygenation and peroxygenation, with a significant improvement in the quality of care. PMID: 32643359 [PubMed - as supplied by publisher]
Source: Minerva Anestesiologica - Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research
CONCLUSIONS: Interfascial dexmedetomidine adjuvant to QLB provided better postoperative analgesia in terms of less morphine consumption, better pain scores and longer time to first analgesic request when compared with the IV dexmedetomidine. PMID: 32643358 [PubMed - as supplied by publisher]
Source: Minerva Anestesiologica - Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research
Publication date: Available online 11 July 2020Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): Federico Boscari, Mario Luca Morieri, Anna Maria Letizia Amato, Valeria Vallone, Ambra Uliana, Anna Baritussio, Nicola Vitturi, Elisa Cipponeri, Francesco Cavallin, Angelo Avogaro, Gian Paolo Fadini, Daniela Bruttomesso
Source: Nutrition, Metabolism and Cardiovascular Diseases - Category: Nutrition Source Type: research
Publication date: Available online 10 July 2020Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): Raffaele Napoli, Antonio Ruvolo, Paola Triggianese, Nella Prevete, Gabriele G. Schiattarella, Cecilia Nigro, Claudia Miele, Fabio Magliulo, Simona Grassi, Antonio Pecoraro, Antonio Cittadini, Giovanni Esposito, Amato de Paulis, Giuseppe Spadaro
Source: Nutrition, Metabolism and Cardiovascular Diseases - Category: Nutrition Source Type: research
Publication date: Available online 10 July 2020Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): Caterina Bonfiglio, Carla Maria Leone, Liciana Vaz de Arruda Silveira, Rocco Guerra, Giovanni Misciagna, Maria Gabriella Caruso, Irene Bruno, Claudia Buongiorno, Angelo Campanella, Vito Maria Bernardo Guerra, Maria Notarnicola, Valentina Deflorio, Isabella Franco, Antonella Bianco, Antonella Mirizzi, Laura Rosana Aballay, Anna Maria Cisternino, Paolo Sorino, Pasqua Letizia Pesole, Alberto Rubén Osella
Source: Nutrition, Metabolism and Cardiovascular Diseases - Category: Nutrition Source Type: research
Publication date: October 2020Source: Journal of Functional Foods, Volume 73Author(s): Christopher M. McLaughlin, Shaun J. Sharkey, Pádraigín Harnedy-Rothwell, Vadivel Parthsarathy, Philip J. Allsopp, Emeir M. McSorley, Richard J. FitzGerald, Finbarr P.M. O'Harte
Source: Journal of Functional Foods - Category: Nutrition Source Type: research
Publication date: Available online 11 July 2020Source: Microbial PathogenesisAuthor(s): Hamidreza Majidiani, Abdolhossein Dalimi, Fatemeh Ghaffarifar, Majid Pirestani, Ali Dalir Ghaffari
Source: Microbial Pathogenesis - Category: Infectious Diseases Source Type: research
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