DARZALEX FASPRO ® (daratumumab and hyaluronidase-fihj) Becomes the First FDA-Approved Treatment for Patients with Newly Diagnosed Light Chain (AL) Amyloidosis
January 15, 2021 (HORSHAM, Pa.) – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today the U.S. Food and Drug Administration (FDA) approval of DARZALEX FASPRO® (daratumumab and hyaluronidase-fihj), a subcutaneous formulation of daratumumab, in combination with bortezomib, cyclophosphamide and dexamethasone (D-VCd) for the treatment of adult patients with newly diagnosed light chain (AL) amyloidosis.[1] DARZALEX FASPRO® is the first and only FDA-approved treatment for patients with this blood cell disorder that is associated with the production of an abnormal protein, which leads to th...
Source: Johnson and Johnson - January 16, 2021 Category: Pharmaceuticals Tags: Our Company Source Type: news

Cost of Constipation Report
In 2018/2019, 76,929 people were admitted in England with constipation, equivalent to 211 people a day and £ 168m was spent by NHS England on treating the condition, which is made up of emergency admissions and laxative prescriptions; these figures have increased since 2017/2018. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - January 15, 2021 Category: Consumer Health News Source Type: news

Cost of constipation still rising in most English regions
The Cost of Constipation report published by the multidisciplinary organisation, the independent Bowel Interest Group, reveals that the cost of avoidable emergency admissions to hospital because of constipation is rising year-on-year in most English regions. (Source: NHS Networks)
Source: NHS Networks - January 14, 2021 Category: UK Health Source Type: news

C-Path PRO Consortium measure used to support an FDA-approved label claim
(Critical Path Institute (C-Path)) C-Path Patient-Reported Outcome Consortium announces that clinical study results using the Consortium's Diary for Irritable Bowel Syndrome Symptoms-Constipation (DIBSS-C) were recently included in the expanded label for the drug LINZESS ® . (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 7, 2021 Category: International Medicine & Public Health Source Type: news

Boost your gut feeling: From a tummy massager to a tracker app, which is the best for IBS? 
JO WATERS: Irritable bowel syndrome (IBS) affects one in ten adults in the UK, causing bloating, diarrhoea, constipation and cramps. We asked a professor to assess some new products to treat it. (Source: the Mail online | Health)
Source: the Mail online | Health - January 5, 2021 Category: Consumer Health News Source Type: news

Heart disease: Constipation could be a lesser-known warning sign of the condition
HEART disease: There are around 7.4 million people living with heart disease according to the British Heart Foundation. Knowing the warning signs and symptoms is crucial. Could your constipation be one of those warnings? (Source: Daily Express - Health)
Source: Daily Express - Health - December 28, 2020 Category: Consumer Health News Source Type: news

Why am I constipated? The five reasons you could be constipated
CONSTIPATION has many possible causes - emotional and physical. What causes constipation? (Source: Daily Express - Health)
Source: Daily Express - Health - December 28, 2020 Category: Consumer Health News Source Type: news

What causes constipation? The five reasons you could be constipated
CONSTIPATION has many possible causes - emotional and physical. What causes constipation? (Source: Daily Express - Health)
Source: Daily Express - Health - December 27, 2020 Category: Consumer Health News Source Type: news

Bowel cancer symptoms: ‘Alternating bouts of constipation and diarrhoea’ could be a sign
BOWEL cancer symptoms can be subtle and easily-missed, but as there's currently no cure it's important to be familiar with what to look out for. One of the most common signs is a change of bowel habits - "alternating bouts of constipation and diarrhoea". (Source: Daily Express - Health)
Source: Daily Express - Health - December 25, 2020 Category: Consumer Health News Source Type: news

How Can You Tell if Your Baby Is Constipated?
Title: How Can You Tell if Your Baby Is Constipated?Category: Diseases and ConditionsCreated: 12/17/2020 12:00:00 AMLast Editorial Review: 12/17/2020 12:00:00 AM (Source: MedicineNet Kids Health General)
Source: MedicineNet Kids Health General - December 17, 2020 Category: Pediatrics Source Type: news

New treatment in development for irritable bowel syndrome with constipation
(Brigham and Women's Hospital) Researchers devised a plan to treat IBS with constipation by delivering chenodeoxycholic acid in a bilayered capsule, finding that this mode of delivery could decrease colon cramping and thus produce a better patient experience. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 8, 2020 Category: International Medicine & Public Health Source Type: news

Home Remedies for Constipation
Title: Home Remedies for ConstipationCategory: Diseases and ConditionsCreated: 12/3/2020 12:00:00 AMLast Editorial Review: 12/3/2020 12:00:00 AM (Source: MedicineNet Digestion General)
Source: MedicineNet Digestion General - December 3, 2020 Category: Nutrition Source Type: news

Does your anxiety trigger IBS symptoms? How to support your digestive system
IRRITABLE bowel syndrome is a common condition that affects the digestive system, causing pain, bloating diarrhoea and constipation. Over the years experts have identified stress as a cause. So what can you do to help avoid a flare-up of symptoms? (Source: Daily Express - Health)
Source: Daily Express - Health - November 24, 2020 Category: Consumer Health News Source Type: news

Rapid Relief of Opioid-Induced Constipation With MNTX Rapid Relief of Opioid-Induced Constipation With MNTX
Subcutaneous use of methylnaltrexone (MNTX) provides rapid relief both for patients with chronic noncancer pain and for those with cancer-related illness.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - November 20, 2020 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Janssen Headlines American Society of Hematology Annual Meeting With More Than 35 Presentations Highlighting Deep, Diverse Oncology Pipeline and Portfolio
RARITAN, N.J., November 5, 2020 – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today more than 35 company-sponsored studies, including 10 oral presentations, will be featured at the 62nd American Society of Hematology (ASH) Annual Meeting and Exposition taking place virtually December 5-8, 2020.In multiple myeloma, highlights include Phase 1b/2 results for the B-cell maturation antigen (BCMA)-targeted chimeric antigen receptor T-cell (CAR-T) therapy ciltacabtagene autoleucel (cilta-cel); new and updated data for the anti-CD38 monoclonal antibody DARZALEX® (daratumumab) and the subcutane...
Source: Johnson and Johnson - November 5, 2020 Category: Pharmaceuticals Tags: Innovation Source Type: news

Intranasal low-dose naltrexone against opioid side effects: a preclinical study - Micheli L, Di Cesare Mannelli L, Lucarini E, Parisio C, Toti A, Fiorentino B, Rigamonti MA, Calosi L, Ghelardini C.
Opioids are broad spectrum analgesics that are an integral part of the therapeutic armamentarium to combat pain in the clinical practice. Unfortunately, together with analgesia, a number of adverse effects can occur such as nausea, vomiting, constipation, ... (Source: SafetyLit)
Source: SafetyLit - October 27, 2020 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Let ’s Talk About Constipation During Pregnancy
Constipation is very common during and after pregnancy, but many women don ’t discuss it with their doctors. (Source: NYT Health)
Source: NYT Health - October 20, 2020 Category: Consumer Health News Authors: Nicholas Bakalar Tags: Pregnancy and Childbirth Constipation Source Type: news

Featured Review: Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network meta-analysis
ConclusionsFor people at higher risk, some medicines worked well to stop them from being sick after general anaesthesia. The most reliable antiemetic medicines were aprepitant, ramosetron, granisetron, dexamethasone, and ondansetron, followed by fosaprepitant and droperidol.However, the authors did not find enough reliable evidence about potential unwanted effects to rank these medicines reliably according to how well they worked.Read the full review on the Cochrane LibraryVisit the Cochrane Anaesthesia Group websiteTuesday, October 20, 2020 (Source: Cochrane News and Events)
Source: Cochrane News and Events - October 15, 2020 Category: Information Technology Authors: Rachel Klabunde Source Type: news

More than 40% of women suffer from constipation during pregnancy and right after childbirth
(University of Eastern Finland) Women are 2-3 times more likely to suffer from constipation during pregnancy and right after childbirth than at any other time in their life, a new study from the University of Eastern Finland shows. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 9, 2020 Category: International Medicine & Public Health Source Type: news

DDT COA #000005: Diary of Irritable Bowel Syndrome Symptoms- Constipation/ Diarrhea/ Mixed (DIBSS-C/D/M)
Clinical Outcome Assessments (COA) Qualification Submissions Office of Drug Evaluation (ODE) III Division of Gastroenterology and Inborn Error Products (DGIEP) DDT COA Number DDT COA #000005 (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - October 6, 2020 Category: Drugs & Pharmacology Authors: FDA Source Type: news

What Helps Constipation Fast
? (Source: eMedicineHealth.com)
Source: eMedicineHealth.com - September 30, 2020 Category: General Medicine Source Type: news

Dr MARTIN SCURR answers your health questions
DR MARTIN SCURR: The term 'constipation' can refer to different things, even among doctors. It may mean infrequent passage of stools, or that what is passed is too hard or too small. (Source: the Mail online | Health)
Source: the Mail online | Health - September 29, 2020 Category: Consumer Health News Source Type: news

Essential oils for the treatment of fungal diseases
(Natural News) Essential oils are known for their use in aromatherapy and massage therapy. When inhaled or applied topically, these natural products exert beneficial effects on mental health. Essential oils can also be used as remedies for common health problems, such as headache, constipation, sinus infections and skin infections. In fact, various essential oils are well-known for their... (Source: NaturalNews.com)
Source: NaturalNews.com - September 25, 2020 Category: Consumer Health News Source Type: news

Roche announces FDA approval of Gavreto (pralsetinib) for the treatment of adults with metastatic RET fusion-positive non-small cell lung cancer
             Basel, 7 September 2020 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced that the United States (US) Food and Drug Administration (FDA) has approved Gavreto ™ (pralsetinib) for the treatment of adults with metastatic rearranged during transfection (RET) fusion-positive non-small cell lung cancer (NSCLC) as detected by an FDA approved test. This indication was approved under the FDA’s Accelerated Approval programme, based on data from the phase I/II ARROW study. Continued approval for this indication may be contingent upon verifica...
Source: Roche Investor Update - September 7, 2020 Category: Pharmaceuticals Source Type: news

Roche announces FDA approval of Gavreto (pralsetinib) for the treatment of adults with metastatic RET fusion-positive non-small cell lung cancer
             Basel, 7 September 2020 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced that the United States (US) Food and Drug Administration (FDA) has approved Gavreto ™ (pralsetinib) for the treatment of adults with metastatic rearranged during transfection (RET) fusion-positive non-small cell lung cancer (NSCLC) as detected by an FDA approved test. This indication was approved under the FDA’s Accelerated Approval programme, based on data from the phase I/II ARROW study. Continued approval for this indication may be contingent upon verifica...
Source: Roche Media News - September 7, 2020 Category: Pharmaceuticals Source Type: news

What Is In A Ketogenic Diet?
Discussion Epilepsy is a common problem for the general pediatrician. Its incidence is estimated at 41-87/100,000 children. While many children are controlled with medication, it is also estimated that up to 1/3 will develop drug-resistant epilepsy. Some children may have an identifiable seizure focus that may be amenable to surgery, but many others do not. One option for potential control is a ketogenic diet (KD). Indications for KD usually are for drug-resistant epilepsy including partial and complex seizure patterns as well as some metabolic disorders such as glucose transport 1 deficiency syndrome. It has also found ...
Source: PediatricEducation.org - September 7, 2020 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Healthy Diets Inversely Linked to Early Parkinson's Symptoms Healthy Diets Inversely Linked to Early Parkinson's Symptoms
Adherence to a healthy eating pattern like the Mediterranean diet is inversely linked to prodromal features of Parkinson's disease, including constipation and depressive symptoms, researchers say.Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - August 21, 2020 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

Studies of gut microbiota and contractility help deal with chronic constipation
(Kazan Federal University) Chronic constipation (CC) remains a serious medical and social problem because the complexity of diagnosis, the lack of a single approach to treatment, and unsatisfactory treatment results. The causes of constipation are varied - from the abnormal anatomical structure of the large intestine and its location in the abdominal cavity to impaired neurohumoral regulation of its motility, endocrine pathology, psychogenic factors, poor nutrition, as well as a combination of these factors. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 20, 2020 Category: International Medicine & Public Health Source Type: news

Efficacy, Safety of Treatments for Opioid-induced Constipation Efficacy, Safety of Treatments for Opioid-induced Constipation
This meta-analysis examined the efficacy and safety of peripherally acting mu-opioid receptor antagonists and other novel treatments for relieving opioid-induced constipation.Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 8, 2020 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Back pain causes: Does constipation cause back pain? Can IBS cause back pain?
BACK PAIN is a common complaint and it usually sorts itself out within a few weeks or months. Here's some possible back pain causes. (Source: Daily Express - Health)
Source: Daily Express - Health - June 29, 2020 Category: Consumer Health News Source Type: news

Children ’ s Robitussin And Dimetapp Cough Medicines Recalled For Potential Overdose Risks
(CNN) — Parents take note: GlaxoSmithKline Consumer Healthcare has voluntarily recalled three lots of its children’s cough syrups — Children’s Robitussin Honey Cough and Chest Congestion DM and Children’s Dimetapp Cold and Cough — due to the products having incorrect dosing cups in their packaging. That means parents might accidentally overdose a child by putting too much syrup in the cup. Symptoms of overdose of either product may include impaired coordination, elevated blood pressure, dizziness, seizure, nausea, vomiting, constipation, diarrhea, abdominal pain, hallucinations, among ot...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - June 19, 2020 Category: Consumer Health News Authors: Health – CBS Boston Tags: Consumer Health News CNN Cough Syrup Recall Source Type: news

Subcutaneous Daratumumab Combination Resulted in Deep and Rapid Hematologic Responses and Improved Clinical Outcomes in the Treatment of Patients with Newly Diagnosed Light Chain (AL) Amyloidosis
RARITAN, NJ, June 13, 2020 – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today results from the first randomized Phase 3 study investigating subcutaneous daratumumab[i] in the treatment of patients with newly diagnosed light chain (AL) amyloidosis, a rare and potentially fatal disease.[1],[2] The data demonstrated subcutaneous daratumumab in combination with cyclophosphamide, bortezomib, and dexamethasone (D-CyBorD) resulted in a higher hematologic complete response rate (CR), (53 percent vs. 18 percent [P
Source: Johnson and Johnson - June 15, 2020 Category: Pharmaceuticals Tags: Innovation Source Type: news

Parkinson’s disease: How often do you poo in a week? Hidden signs of Parkinson’s
PARKINSON'S disease symptoms develop slowly over a long period of time, and could be caused by nerve damage in the brain. One of the more common warning signs of the neurodegenerative brain condition is constipation. How often do you poo in a single week? (Source: Daily Express - Health)
Source: Daily Express - Health - June 9, 2020 Category: Consumer Health News Source Type: news

Too Much or Too Little Sleep Spikes Constipation Too Much or Too Little Sleep Spikes Constipation
People who sleep more or less than average report significantly more constipation than those who sleep 7 to 8 hours a night, new research shows.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - May 22, 2020 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

Scientists say barley is a promising laxative and functional food against constipation
(Natural News) According to a recent study published in BMC Complementary Medicine and Therapies, fermented barley extract is a promising laxative agent and natural remedy for spastic constipation. After investigating its effects in constipated rats, South Korean researchers reported that fermented barley exhibits antioxidant, gastroprotective and immunostimulatory properties that make it a powerful functional food ingredient against spastic... (Source: NaturalNews.com)
Source: NaturalNews.com - May 15, 2020 Category: Consumer Health News Source Type: news

Ronald Reagan ’s Secret Cancer Cure
There’s no faster way to purify your body of viruses, bacteria and fungi — and at the same time ramp up your immune system — than a 125-year-old “cure” banned by the FDA. I’m talking about ozone therapy — and it’s not just good for cleansing your body. You see, ozone — a special “energized” kind of oxygen — can help heal almost any condition. Despite being banned by the FDA back in the 1940s, after more than 60 years of successful use, ozone therapy has saved millions of lives in countries where it has become a commonplace medical treatment. In count...
Source: Al Sears, MD Natural Remedies - May 12, 2020 Category: Complementary Medicine Authors: Dr.A.Sears Tags: Health Source Type: news

Why do people with depression usually suffer from gastrointestinal distress? Study
(Natural News) Patients with depression often experience gastrointestinal distress, a group of digestive disorders marked by lingering symptoms, such as constipation, bloating, diarrhea, abdominal pain and cramping. According to a study published in the journal Gastroenterology, the two disorders are connected by a common cause: low levels of serotonin, also known the “happy chemical.” Depression and gastrointestinal distress go hand... (Source: NaturalNews.com)
Source: NaturalNews.com - May 8, 2020 Category: Consumer Health News Source Type: news

Constipation: How to relieve constipation
CONSTIPATION is extremely common and affects people of all ages. Here's how to treat it at home. (Source: Daily Express - Health)
Source: Daily Express - Health - May 6, 2020 Category: Consumer Health News Source Type: news

Roche ’s risdiplam shows significant improvement in survival and motor milestones in infants with Type 1 spinal muscular atrophy (SMA)
Basel, 28 April 2020 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today presented 1-year data from FIREFISH Part 2, a pivotal global study evaluating risdiplam in infants aged 1 – 7 months old with symptomatic Type 1 spinal muscular atrophy (SMA). The study met its primary endpoint with 29% of infants (12/41; p
Source: Roche Investor Update - April 28, 2020 Category: Pharmaceuticals Source Type: news

Roche ’s risdiplam shows significant improvement in survival and motor milestones in infants with Type 1 spinal muscular atrophy (SMA)
Basel, 28 April 2020 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today presented 1-year data from FIREFISH Part 2, a pivotal global study evaluating risdiplam in infants aged 1 – 7 months old with symptomatic Type 1 spinal muscular atrophy (SMA). The study met its primary endpoint with 29% of infants (12/41; p
Source: Roche Media News - April 28, 2020 Category: Pharmaceuticals Source Type: news

Bowel cancer symptoms: How long has your constipation lasted? Sign of the deadly disease
BOWEL Cancer Awareness month is here. The condition is often treatable and curable with an early diagnosis. Learn the symptoms to look out for in order to protect yourself. What are the signs of the disease? (Source: Daily Express - Health)
Source: Daily Express - Health - April 3, 2020 Category: Consumer Health News Source Type: news

Low intrinsic efficacy for G protein activation can explain the improved side effect profiles of new opioid agonists
Biased agonism at G protein–coupled receptors describes the phenomenon whereby some drugs can activate some downstream signaling activities to the relative exclusion of others. Descriptions of biased agonism focusing on the differential engagement of G proteins versus β-arrestins are commonly limited by the small response windows obtained in pathways that are not amplified or are less effectively coupled to receptor engagement, such as β-arrestin recruitment. At the μ-opioid receptor (MOR), G protein–biased ligands have been proposed to induce less constipation and respiratory depressant side effec...
Source: Signal Transduction Knowledge Environment - March 30, 2020 Category: Science Authors: Gillis, A., Gondin, A. B., Kliewer, A., Sanchez, J., Lim, H. D., Alamein, C., Manandhar, P., Santiago, M., Fritzwanker, S., Schmidel, F., Katte, T. A., Reekie, T., Grimsey, N. L., Kassiou, M., Kellam, B., Krasel, C., Halls, M. L., Connor, M., Lane, J. R., Tags: STKE Research Articles Source Type: news

"Imaginary" pain could be caused by serotonin deficiency, study says
(Natural News) Somatic awareness refers to a type of mindfulness that focuses on what happens to your body. More often than not, heightened somatic awareness is often accompanied by “medically unexplained symptoms” like headaches, nausea constipation, itchy skin or sore joints. This condition is also often associated with illnesses like fibromyalgia, rheumatoid arthritis and temporomandibular... (Source: NaturalNews.com)
Source: NaturalNews.com - March 11, 2020 Category: Consumer Health News Source Type: news

What Are Some Risk Factors for Cerebral Palsy?
Discussion The term, cerebral palsy, or CP has gone through many iterations with the first description in 1861 by W.J. Little who described it as “The condition of spastic rigidity of the limbs of newborn children.” The most recent definition is from Rosenbaun et al. in 2007 which states it is “a group of permanent disorders of the development of movement and posture, causing activity limitation, that are attributed to non-progressive disturbances that occurred in the developing fetal or infant brain. The motor disorders of cerebral palsy are often accompanied by disturbances of sensation, perception, cog...
Source: PediatricEducation.org - March 9, 2020 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Electrical stimulation helps treat constipation in clinical trial
(Wiley) Electrical stimulation benefited women with constipation in a recent clinical trial published in Alimentary Pharmacology& Therapeutics. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 4, 2020 Category: International Medicine & Public Health Source Type: news

FDA Approves Pizensy (lactitol) for the Treatment of Chronic Idiopathic Constipation in Adults
Braintree, Mass. March 02, 2020 -- Sebela Pharmaceuticals announced today that the U.S. Food and Drug Administration (FDA) has approved Pizensy (lactitol) for oral solution for the once-daily treatment of chronic idiopathic constipation (CIC)... (Source: Drugs.com - New Drug Approvals)
Source: Drugs.com - New Drug Approvals - March 2, 2020 Category: Drugs & Pharmacology Source Type: news

AstraZeneca divests global rights to Movantik
AstraZeneca has agreed to sublicense its global rights to Movantik (naloxegol), excluding Europe, Canada and Israel, to RedHill Biopharma (RedHill). Movantik is a peripherally acting mu-opioid receptor antagonist (PAMORA) indicated for the treatment of opioid-induced constipation (OIC). (Source: World Pharma News)
Source: World Pharma News - February 25, 2020 Category: Pharmaceuticals Tags: Featured AstraZeneca Business and Industry Source Type: news

FDA OKs New Drug for Chronic Idiopathic Constipation FDA OKs New Drug for Chronic Idiopathic Constipation
Lactitol (Pizensy) is an osmotic laxative taken once daily for treatment in adults with chronic idiopathic constipation.FDA Approvals (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - February 13, 2020 Category: Gastroenterology Tags: Gastroenterology News Alert Source Type: news

Janssen Announces Submission to U.S. FDA for New DARZALEX ® (Daratumumab)-Based Combination Regimen for Patients with Relapsed/Refractory Multiple Myeloma
RARITAN, NJ, February 10, 2020 – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today the submission of a supplemental Biologics License Application (sBLA) to the U.S. Food and Drug Administration (FDA) seeking approval of DARZALEX® (daratumumab) in combination with Kyprolis® (carfilzomib) and dexamethasone (DKd) for relapsed/refractory multiple myeloma. The sBLA is supported by results from the Phase 3 CANDOR study, which compared treatment with DKd to carfilzomib and dexamethasone (Kd) in patients with multiple myeloma who relapsed after one to three prior lines of therapy. “W...
Source: Johnson and Johnson - February 10, 2020 Category: Pharmaceuticals Tags: Innovation Source Type: news

Janssen to Highlight Depth of Solid Tumor Portfolio at ASCO GU
RARITAN, N.J., February 3, 2020 – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today multiple data presentations from a robust solid tumor portfolio that will be featured at the American Society of Clinical Oncology Genitourinary (ASCO GU) Cancers Symposium, taking place February 13-15 in San Francisco. Company-sponsored data presentations will include clinical results for ERLEADA® (apalutamide) and niraparib in prostate cancer; and BALVERSA™ (erdafitinib) in bladder cancer. “We are committed to improving outcomes in patients with prostate and bladder cancer where high unmet...
Source: Johnson and Johnson - February 3, 2020 Category: Pharmaceuticals Tags: Innovation Source Type: news