Diabetes type 2 symptoms: Constipation may indicate nerve damage
DIABETES may continue to disrupt your internal processes, with symptoms so slight, you don't realise the significant damage being done inside. Struggling to release bowel movements might be more sinister than once thought. (Source: Daily Express - Health)
Source: Daily Express - Health - April 18, 2021 Category: Consumer Health News Source Type: news

Constipation treatment Vibrant raises $7.5 million led by Unorthodox Ventures
Sequoia Capital invests for fourth time as treatment continues third round of FDA trials YOKNEAM ILLIT, Israel, March 26, 2021 -- (Healthcare Sales & Marketing Network) -- Vibrant, a leading developer of gastrointestinal treatments, today announced the... Devices, Gastroenterology, Venture Capital Vibrant Ltd, vibrating capsule (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - March 26, 2021 Category: Pharmaceuticals Source Type: news

What Are Generalized Anxiety Disorder Treatment Components?
Discussion Generalized anxiety disorder (GAD) is “…excessive anxiety and worry about a number of events and activities coupled with at least one physical symptom, which may include fatigue, poor concentration, restlessness, irritability, muscle tension, and sleep difficulties.” Other ways it presents to the primary care office may be abdominal pain, headache or heart palpitations, dizziness, syncope, numbness, trembling, paresthesia, memory loss, or urinary frequency. It has an estimated prevalence of 15% and is the second most common anxiety disorder in children after social anxiety disorder. GAD can co...
Source: PediatricEducation.org - March 15, 2021 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

FDA qualifies C-Path's Diary for Irritable Bowel Syndrome Symptoms-Constipation (DIBSS-C)
(Critical Path Institute (C-Path)) C-Path Patient-Reported Outcome Consortium announces the qualification of the Diary for Irritable Bowel Syndrome Symptoms-Constipation by FDA. The DIBSS-C was developed by the PRO Consortium's Irritable Bowel Syndrome Working Group to support symptom-based efficacy endpoints in clinical trials for products intended to treat constipation-predominant IBS in adults. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 9, 2021 Category: International Medicine & Public Health Source Type: news

Splinting: What is it and is the TikTok constipation hack dangerous?
SPLINTING is not a new thing and according to TikTok users, it's an effective hack to solve constipation. But is splinting dangerous? (Source: Daily Express - Health)
Source: Daily Express - Health - March 4, 2021 Category: Consumer Health News Source Type: news

What Is the Difference Between Fecal Impaction and Constipation?
Title: What Is the Difference Between Fecal Impaction and Constipation?Category: Diseases and ConditionsCreated: 3/4/2021 12:00:00 AMLast Editorial Review: 3/4/2021 12:00:00 AM (Source: MedicineNet Digestion General)
Source: MedicineNet Digestion General - March 4, 2021 Category: Nutrition Source Type: news

Antidepressants could be prescribed by GPs as the new weapon in the war on Irritable Bowel Syndrome
IBS affects nine million Britons, causing agonising pain, bloating, diarrhoea and constipation - with few effective treatments available. (Source: the Mail online | Health)
Source: the Mail online | Health - February 27, 2021 Category: Consumer Health News Source Type: news

Roche receives positive CHMP opinion for Evrysdi, the first and only at home spinal muscular atrophy (SMA) treatment with proven efficacy in adults, children and infants two months and older
Basel, 26 February 2021 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced that the European Medicines Agency (EMA) Committee for Medicinal Products for Human Use (CHMP) has recommended the approval of Evrysdi ™ (risdiplam) for the treatment of 5q spinal muscular atrophy (SMA) in patients 2 months of age and older, with a clinical diagnosis of SMA Type 1, Type 2 or Type 3 or with one to four SMN2 copies. SMA is a leading genetic cause of death in infants and 5q SMA is the most common form of the disease . SMA causes progressive muscle weakness and atrophy, and significant unmet need remains, particularly in adults ...
Source: Roche Media News - February 26, 2021 Category: Pharmaceuticals Source Type: news

Roche receives positive CHMP opinion for Evrysdi, the first and only at home spinal muscular atrophy (SMA) treatment with proven efficacy in adults, children and infants two months and older
Basel, 26 February 2021 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced that the European Medicines Agency (EMA) Committee for Medicinal Products for Human Use (CHMP) has recommended the approval of Evrysdi ™ (risdiplam) for the treatment of 5q spinal muscular atrophy (SMA) in patients 2 months of age and older, with a clinical diagnosis of SMA Type 1, Type 2 or Type 3 or with one to four SMN2 copies. SMA is a leading genetic cause of death in infants and 5q SMA is the most common form of the disease . SMA causes progressive muscle weakness and atrophy, and significant unmet need remains, particularly in adults ...
Source: Roche Investor Update - February 26, 2021 Category: Pharmaceuticals Source Type: news

What Can Constipation be a Sign Of?
Title: What Can Constipation be a Sign Of?Category: Diseases and ConditionsCreated: 2/24/2021 12:00:00 AMLast Editorial Review: 2/24/2021 12:00:00 AM (Source: MedicineNet Digestion General)
Source: MedicineNet Digestion General - February 24, 2021 Category: Nutrition Source Type: news

Toxic Clostridioides (formerly Clostridium) difficile colitis: No longer a diarrhea associated infection, American journal of surgery 221(1): 240-242
Conclusion: CDI must be suspected in patients who rapidly develop abdominal distention, vague abdominal complaints or change in bowel function even in the absence of diarrhea, especially if coupled with multi-system organ failure. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - February 19, 2021 Category: Consumer Health News Source Type: news

Constipation Remedies
Title: Constipation RemediesCategory: Diseases and ConditionsCreated: 12/31/1997 12:00:00 AMLast Editorial Review: 2/18/2021 12:00:00 AM (Source: MedicineNet Digestion General)
Source: MedicineNet Digestion General - February 18, 2021 Category: Nutrition Source Type: news

Prostate cancer: Stomach pain, constipation or blood in stools are signs not to ignore
PROSTATE cancer is the most common cancer in men in the UK, with around 40,000 men diagnosed with prostate cancer every year in England alone. Symptoms can take years to surface and when the cancer has advanced there are three warning signs you should not ignore. (Source: Daily Express - Health)
Source: Daily Express - Health - February 12, 2021 Category: Consumer Health News Source Type: news

What Are Some Home Remedies I Can Give My Child for Constipation?
Title: What Are Some Home Remedies I Can Give My Child for Constipation?Category: Diseases and ConditionsCreated: 2/10/2021 12:00:00 AMLast Editorial Review: 2/10/2021 12:00:00 AM (Source: MedicineNet Kids Health General)
Source: MedicineNet Kids Health General - February 10, 2021 Category: Pediatrics Source Type: news

Janssen to Highlight Robust Solid Tumor Portfolio and Pipeline at 2021 ASCO GU
February 2, 2021 (RARITAN, N.J.) – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today it will highlight the depth of its solid tumor portfolio at the American Society of Clinical Oncology Genitourinary (ASCO GU) Cancers Symposium with 12 data presentations, including three company-sponsored oral presentations from the ERLEADA® (apalutamide) clinical development program. The virtual meeting will take place February 11-13, 2021. “We are committed to the development of innovative therapies for patients with genitourinary cancers for whom there remains a high unmet need,” said C...
Source: Johnson and Johnson - February 2, 2021 Category: Pharmaceuticals Tags: Our Company Source Type: news

Elobixibat: A Novel Treatment for Chronic Constipation Elobixibat: A Novel Treatment for Chronic Constipation
Elobixibat, a novel ileal bile acid transport inhibitor, appears to be a safe and effective treatment for chronic constipation.Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 27, 2021 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

DDT COA #000005: Diary for Irritable Bowel Syndrome Symptoms – Constipation (DIBSS-C)
DDT COA #000005: Diary for Irritable Bowel Syndrome Symptoms – Constipation (DIBSS-C) (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - January 26, 2021 Category: Drugs & Pharmacology Authors: FDA Source Type: news

What Helps Constipation Fast?
Title: What Helps Constipation Fast?Category: Diseases and ConditionsCreated: 1/25/2021 12:00:00 AMLast Editorial Review: 1/25/2021 12:00:00 AM (Source: MedicineNet Digestion General)
Source: MedicineNet Digestion General - January 25, 2021 Category: Nutrition Source Type: news

Is Constipation a Symptom of Cancer
? (Source: eMedicineHealth.com)
Source: eMedicineHealth.com - January 21, 2021 Category: General Medicine Source Type: news

DARZALEX FASPRO ® (daratumumab and hyaluronidase-fihj) Becomes the First FDA-Approved Treatment for Patients with Newly Diagnosed Light Chain (AL) Amyloidosis
January 15, 2021 (HORSHAM, Pa.) – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today the U.S. Food and Drug Administration (FDA) approval of DARZALEX FASPRO® (daratumumab and hyaluronidase-fihj), a subcutaneous formulation of daratumumab, in combination with bortezomib, cyclophosphamide and dexamethasone (D-VCd) for the treatment of adult patients with newly diagnosed light chain (AL) amyloidosis.[1] DARZALEX FASPRO® is the first and only FDA-approved treatment for patients with this blood cell disorder that is associated with the production of an abnormal protein, which leads to th...
Source: Johnson and Johnson - January 16, 2021 Category: Pharmaceuticals Tags: Our Company Source Type: news

Cost of Constipation Report
In 2018/2019, 76,929 people were admitted in England with constipation, equivalent to 211 people a day and £ 168m was spent by NHS England on treating the condition, which is made up of emergency admissions and laxative prescriptions; these figures have increased since 2017/2018. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - January 15, 2021 Category: Consumer Health News Source Type: news

Cost of constipation still rising in most English regions
The Cost of Constipation report published by the multidisciplinary organisation, the independent Bowel Interest Group, reveals that the cost of avoidable emergency admissions to hospital because of constipation is rising year-on-year in most English regions. (Source: NHS Networks)
Source: NHS Networks - January 14, 2021 Category: UK Health Source Type: news

C-Path PRO Consortium measure used to support an FDA-approved label claim
(Critical Path Institute (C-Path)) C-Path Patient-Reported Outcome Consortium announces that clinical study results using the Consortium's Diary for Irritable Bowel Syndrome Symptoms-Constipation (DIBSS-C) were recently included in the expanded label for the drug LINZESS ® . (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 7, 2021 Category: International Medicine & Public Health Source Type: news

Boost your gut feeling: From a tummy massager to a tracker app, which is the best for IBS? 
JO WATERS: Irritable bowel syndrome (IBS) affects one in ten adults in the UK, causing bloating, diarrhoea, constipation and cramps. We asked a professor to assess some new products to treat it. (Source: the Mail online | Health)
Source: the Mail online | Health - January 5, 2021 Category: Consumer Health News Source Type: news

Heart disease: Constipation could be a lesser-known warning sign of the condition
HEART disease: There are around 7.4 million people living with heart disease according to the British Heart Foundation. Knowing the warning signs and symptoms is crucial. Could your constipation be one of those warnings? (Source: Daily Express - Health)
Source: Daily Express - Health - December 28, 2020 Category: Consumer Health News Source Type: news

Why am I constipated? The five reasons you could be constipated
CONSTIPATION has many possible causes - emotional and physical. What causes constipation? (Source: Daily Express - Health)
Source: Daily Express - Health - December 28, 2020 Category: Consumer Health News Source Type: news

What causes constipation? The five reasons you could be constipated
CONSTIPATION has many possible causes - emotional and physical. What causes constipation? (Source: Daily Express - Health)
Source: Daily Express - Health - December 27, 2020 Category: Consumer Health News Source Type: news

Bowel cancer symptoms: ‘Alternating bouts of constipation and diarrhoea’ could be a sign
BOWEL cancer symptoms can be subtle and easily-missed, but as there's currently no cure it's important to be familiar with what to look out for. One of the most common signs is a change of bowel habits - "alternating bouts of constipation and diarrhoea". (Source: Daily Express - Health)
Source: Daily Express - Health - December 25, 2020 Category: Consumer Health News Source Type: news

How Can You Tell if Your Baby Is Constipated?
Title: How Can You Tell if Your Baby Is Constipated?Category: Diseases and ConditionsCreated: 12/17/2020 12:00:00 AMLast Editorial Review: 12/17/2020 12:00:00 AM (Source: MedicineNet Kids Health General)
Source: MedicineNet Kids Health General - December 17, 2020 Category: Pediatrics Source Type: news

New treatment in development for irritable bowel syndrome with constipation
(Brigham and Women's Hospital) Researchers devised a plan to treat IBS with constipation by delivering chenodeoxycholic acid in a bilayered capsule, finding that this mode of delivery could decrease colon cramping and thus produce a better patient experience. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 8, 2020 Category: International Medicine & Public Health Source Type: news

Home Remedies for Constipation
Title: Home Remedies for ConstipationCategory: Diseases and ConditionsCreated: 12/3/2020 12:00:00 AMLast Editorial Review: 12/3/2020 12:00:00 AM (Source: MedicineNet Digestion General)
Source: MedicineNet Digestion General - December 3, 2020 Category: Nutrition Source Type: news

Does your anxiety trigger IBS symptoms? How to support your digestive system
IRRITABLE bowel syndrome is a common condition that affects the digestive system, causing pain, bloating diarrhoea and constipation. Over the years experts have identified stress as a cause. So what can you do to help avoid a flare-up of symptoms? (Source: Daily Express - Health)
Source: Daily Express - Health - November 24, 2020 Category: Consumer Health News Source Type: news

Rapid Relief of Opioid-Induced Constipation With MNTX Rapid Relief of Opioid-Induced Constipation With MNTX
Subcutaneous use of methylnaltrexone (MNTX) provides rapid relief both for patients with chronic noncancer pain and for those with cancer-related illness.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - November 20, 2020 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Janssen Headlines American Society of Hematology Annual Meeting With More Than 35 Presentations Highlighting Deep, Diverse Oncology Pipeline and Portfolio
RARITAN, N.J., November 5, 2020 – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today more than 35 company-sponsored studies, including 10 oral presentations, will be featured at the 62nd American Society of Hematology (ASH) Annual Meeting and Exposition taking place virtually December 5-8, 2020.In multiple myeloma, highlights include Phase 1b/2 results for the B-cell maturation antigen (BCMA)-targeted chimeric antigen receptor T-cell (CAR-T) therapy ciltacabtagene autoleucel (cilta-cel); new and updated data for the anti-CD38 monoclonal antibody DARZALEX® (daratumumab) and the subcutane...
Source: Johnson and Johnson - November 5, 2020 Category: Pharmaceuticals Tags: Innovation Source Type: news

Intranasal low-dose naltrexone against opioid side effects: a preclinical study - Micheli L, Di Cesare Mannelli L, Lucarini E, Parisio C, Toti A, Fiorentino B, Rigamonti MA, Calosi L, Ghelardini C.
Opioids are broad spectrum analgesics that are an integral part of the therapeutic armamentarium to combat pain in the clinical practice. Unfortunately, together with analgesia, a number of adverse effects can occur such as nausea, vomiting, constipation, ... (Source: SafetyLit)
Source: SafetyLit - October 27, 2020 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Let ’s Talk About Constipation During Pregnancy
Constipation is very common during and after pregnancy, but many women don ’t discuss it with their doctors. (Source: NYT Health)
Source: NYT Health - October 20, 2020 Category: Consumer Health News Authors: Nicholas Bakalar Tags: Pregnancy and Childbirth Constipation Source Type: news

Featured Review: Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network meta-analysis
ConclusionsFor people at higher risk, some medicines worked well to stop them from being sick after general anaesthesia. The most reliable antiemetic medicines were aprepitant, ramosetron, granisetron, dexamethasone, and ondansetron, followed by fosaprepitant and droperidol.However, the authors did not find enough reliable evidence about potential unwanted effects to rank these medicines reliably according to how well they worked.Read the full review on the Cochrane LibraryVisit the Cochrane Anaesthesia Group websiteTuesday, October 20, 2020 (Source: Cochrane News and Events)
Source: Cochrane News and Events - October 15, 2020 Category: Information Technology Authors: Rachel Klabunde Source Type: news

More than 40% of women suffer from constipation during pregnancy and right after childbirth
(University of Eastern Finland) Women are 2-3 times more likely to suffer from constipation during pregnancy and right after childbirth than at any other time in their life, a new study from the University of Eastern Finland shows. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 9, 2020 Category: International Medicine & Public Health Source Type: news

DDT COA #000005: Diary of Irritable Bowel Syndrome Symptoms- Constipation/ Diarrhea/ Mixed (DIBSS-C/D/M)
Clinical Outcome Assessments (COA) Qualification Submissions Office of Drug Evaluation (ODE) III Division of Gastroenterology and Inborn Error Products (DGIEP) DDT COA Number DDT COA #000005 (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - October 6, 2020 Category: Drugs & Pharmacology Authors: FDA Source Type: news

What Helps Constipation Fast
? (Source: eMedicineHealth.com)
Source: eMedicineHealth.com - September 30, 2020 Category: General Medicine Source Type: news

Dr MARTIN SCURR answers your health questions
DR MARTIN SCURR: The term 'constipation' can refer to different things, even among doctors. It may mean infrequent passage of stools, or that what is passed is too hard or too small. (Source: the Mail online | Health)
Source: the Mail online | Health - September 29, 2020 Category: Consumer Health News Source Type: news

Essential oils for the treatment of fungal diseases
(Natural News) Essential oils are known for their use in aromatherapy and massage therapy. When inhaled or applied topically, these natural products exert beneficial effects on mental health. Essential oils can also be used as remedies for common health problems, such as headache, constipation, sinus infections and skin infections. In fact, various essential oils are well-known for their... (Source: NaturalNews.com)
Source: NaturalNews.com - September 25, 2020 Category: Consumer Health News Source Type: news

Roche announces FDA approval of Gavreto (pralsetinib) for the treatment of adults with metastatic RET fusion-positive non-small cell lung cancer
             Basel, 7 September 2020 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced that the United States (US) Food and Drug Administration (FDA) has approved Gavreto ™ (pralsetinib) for the treatment of adults with metastatic rearranged during transfection (RET) fusion-positive non-small cell lung cancer (NSCLC) as detected by an FDA approved test. This indication was approved under the FDA’s Accelerated Approval programme, based on data from the phase I/II ARROW study. Continued approval for this indication may be contingent upon verifica...
Source: Roche Investor Update - September 7, 2020 Category: Pharmaceuticals Source Type: news

Roche announces FDA approval of Gavreto (pralsetinib) for the treatment of adults with metastatic RET fusion-positive non-small cell lung cancer
             Basel, 7 September 2020 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced that the United States (US) Food and Drug Administration (FDA) has approved Gavreto ™ (pralsetinib) for the treatment of adults with metastatic rearranged during transfection (RET) fusion-positive non-small cell lung cancer (NSCLC) as detected by an FDA approved test. This indication was approved under the FDA’s Accelerated Approval programme, based on data from the phase I/II ARROW study. Continued approval for this indication may be contingent upon verifica...
Source: Roche Media News - September 7, 2020 Category: Pharmaceuticals Source Type: news

What Is In A Ketogenic Diet?
Discussion Epilepsy is a common problem for the general pediatrician. Its incidence is estimated at 41-87/100,000 children. While many children are controlled with medication, it is also estimated that up to 1/3 will develop drug-resistant epilepsy. Some children may have an identifiable seizure focus that may be amenable to surgery, but many others do not. One option for potential control is a ketogenic diet (KD). Indications for KD usually are for drug-resistant epilepsy including partial and complex seizure patterns as well as some metabolic disorders such as glucose transport 1 deficiency syndrome. It has also found ...
Source: PediatricEducation.org - September 7, 2020 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Healthy Diets Inversely Linked to Early Parkinson's Symptoms Healthy Diets Inversely Linked to Early Parkinson's Symptoms
Adherence to a healthy eating pattern like the Mediterranean diet is inversely linked to prodromal features of Parkinson's disease, including constipation and depressive symptoms, researchers say.Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - August 21, 2020 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

Studies of gut microbiota and contractility help deal with chronic constipation
(Kazan Federal University) Chronic constipation (CC) remains a serious medical and social problem because the complexity of diagnosis, the lack of a single approach to treatment, and unsatisfactory treatment results. The causes of constipation are varied - from the abnormal anatomical structure of the large intestine and its location in the abdominal cavity to impaired neurohumoral regulation of its motility, endocrine pathology, psychogenic factors, poor nutrition, as well as a combination of these factors. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 20, 2020 Category: International Medicine & Public Health Source Type: news

Efficacy, Safety of Treatments for Opioid-induced Constipation Efficacy, Safety of Treatments for Opioid-induced Constipation
This meta-analysis examined the efficacy and safety of peripherally acting mu-opioid receptor antagonists and other novel treatments for relieving opioid-induced constipation.Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 8, 2020 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Back pain causes: Does constipation cause back pain? Can IBS cause back pain?
BACK PAIN is a common complaint and it usually sorts itself out within a few weeks or months. Here's some possible back pain causes. (Source: Daily Express - Health)
Source: Daily Express - Health - June 29, 2020 Category: Consumer Health News Source Type: news

Children ’ s Robitussin And Dimetapp Cough Medicines Recalled For Potential Overdose Risks
(CNN) — Parents take note: GlaxoSmithKline Consumer Healthcare has voluntarily recalled three lots of its children’s cough syrups — Children’s Robitussin Honey Cough and Chest Congestion DM and Children’s Dimetapp Cold and Cough — due to the products having incorrect dosing cups in their packaging. That means parents might accidentally overdose a child by putting too much syrup in the cup. Symptoms of overdose of either product may include impaired coordination, elevated blood pressure, dizziness, seizure, nausea, vomiting, constipation, diarrhea, abdominal pain, hallucinations, among ot...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - June 19, 2020 Category: Consumer Health News Authors: Health – CBS Boston Tags: Consumer Health News CNN Cough Syrup Recall Source Type: news