Mayo Clinic Q and A: Constipation in children
DEAR MAYO CLINIC: My 10-year-old daughter spends hours in the bathroom daily. Every time I inquire, she tells me she is constipated. We do not eat out a lot, and we incorporate fruits or vegetables at each meal. She also drinks water most of the day. Is constipation normal at this age, and what can I do to help her? ANSWER: Constipation can cause issues with bowel movements in as many as 30% of children. It's a common… (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - September 17, 2021 Category: Databases & Libraries Source Type: news

Cochrane Library Editorial - Anticholinergic drugs and dementia: time for transparency in the face of uncertainty
 Would you choose a treatment option that might increase your risk of developing dementia?Anticholinergic drugs (which contract smooth muscle, reduce heart rate, dilate blood vessels, and increase bodily secretions)  are commonly used in clinical practice for the management of many conditions affecting older adults - for example for urinary incontinence and for treating depression. As a consequence, the cumulative anticholinergic exposure for older people taking medications for multiple health conditions can b e underestimated. The sum of this exposure is called anticholinergic burden (ACB). Some anticholinergic drug adv...
Source: Cochrane News and Events - September 8, 2021 Category: Information Technology Authors: Muriah Umoquit Source Type: news

Janssen Demonstrates Commitment to Advancing Science and Innovation in the Treatment of Solid Tumors at ESMO Annual Congress
September 8, 2021 (RARITAN, N.J.) – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today that more than ten data presentations from its lung cancer, bladder cancer and prostate cancer portfolio and pipeline will be featured during the European Society for Medical Oncology (ESMO) Annual Congress 2021 virtual meeting, September 16–21. Further details about these data and the science Janssen is advancing will be made available throughout ESMO via the Janssen Oncology Virtual Newsroom.“With a diverse oncology portfolio and pipeline spanning bladder cancer, lung cancer and prostate cancer, Janssen...
Source: Johnson and Johnson - September 8, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

Association between abuse and neglect with functional constipation and irritable bowel syndrome in adolescents - Thomaz de Almeida CN, Tahan S, Areco KN, Morais MB.
OBJECTIVES: To evaluate the association between violence exposure, abuse, and neglect victimization with functional constipation and irritable bowel syndrome in adolescents. METHODS: Observational cross-sectional case-control study conducted with a... (Source: SafetyLit)
Source: SafetyLit - September 6, 2021 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

How does Lichen Sclerosus et Atrophicus Present?
Discussion Lichen sclerosus et atrophicus (LSA) is a chronic inflammatory disease with a strong autoimmune association. It can occur with other autoimmune diseases. Its specific cause is unknown. It affects females and males of all ages, but especially females 40-60 years. In the pediatric population it affects prepubertal females most often. Treatment includes steroid medications or anti-inflammatory medications. Other treatments may be offered including phototherapy, and much less commonly systemic steroids or immunosuppressive therapy. Circumcision may also be an option for some males. Childhood LSA generally improves b...
Source: PediatricEducation.org - September 6, 2021 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Constipation diet: The ONE surprising fruit that could treat constipation
CONSTIPATION affects nearly 30 percent of the population, but what if ONE fruit could treat it? (Source: Daily Express - Health)
Source: Daily Express - Health - August 30, 2021 Category: Consumer Health News Source Type: news

Science Saturday: How disease, diet, and genomics interact with gut virome
Mayo Clinic researchers published a comprehensive analysis of the gut virome in  Gastroenterology, showing how disease, diet and genomics interact with the gut virome in irritable bowel syndrome. This common disorder affects the intestine and manifests as abdominal pain associated with constipation, diarrhea or both. The gut virome is one component of the microbiome (bacteria , fungi, viruses). It includes viruses that specifically attack bacteria (bacteriophages/phages) or those affecting humans (eukaryotic viruses. e.g., norovirus). Hence the gut virome… (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - August 21, 2021 Category: Databases & Libraries Source Type: news

Janssen Presents Phase 1 Results for RYBREVANTTM (amivantamab-vmjw) in the Treatment of Patients with Advanced Non-Small Cell Lung Cancer with MET Exon 14 Skipping Mutations
August 19, 2021 (RARITAN, N.J.) – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced preliminary data from the Phase 1 CHRYSALIS study evaluating RYBREVANTTM (amivantamab-vmjw) for the treatment of patients with non-small cell lung cancer (NSCLC) with mesenchymal-epithelial transition (MET) exon 14 skipping (METex14) mutations. The initial data showed anti-tumor activity in patients with METex14 mutations and a safety profile consistent with reported experience at the approved CHRYSALIS Phase 2 dose (RYBREVANTTM 1050 mg [<80 kg] / 1400 mg [≥80 kg]).[1] These findings will be featured at th...
Source: Johnson and Johnson - August 19, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

Mayo Clinic Q and A: Increasing fiber intake for constipation relief
DEAR MAYO CLINIC: I experience constipation almost weekly, and eating bran flakes every day isn ’t helping. Are fiber supplements safe to use regularly and long term? Is there anything else I can do? I’m a 53-year-old woman and otherwise in excellent health. ANSWER: When consumed at recommended levels, dietary fiber is widely recognized to have health benefits, including relief of constipation. Adult women 50 and younger should consume at least 25 grams of fiber a day. Women… (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - August 10, 2021 Category: Databases & Libraries Source Type: news

Stomach bloating: Want to beat the bloat? Five reasons you should take digestive enzymes
LOOKING for how to beat the bloat? Taking digestive enzymes could be the answer, according to nutritionist Rob Thorp. And there are other reasons why you should be taking them too - from boosting your energy levels to curbing constipation. (Source: Daily Express - Health)
Source: Daily Express - Health - August 8, 2021 Category: Consumer Health News Source Type: news

Data for Roche ’s Evrysdi® (risdiplam) published in New England Journal of Medicine shows significant improvement in survival and motor milestones in babies with Type 1 spinal muscular atrophy (SMA)
Basel, 29 July 2021 – Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced that the New England Journal of Medicine (NEJM) has published data from FIREFISH Part 2, a pivotal global study evaluating the efficacy and safety of Evrysdi® (risdiplam) in babies aged 1-7 months old with symptomatic Type 1 spinal muscular atr ophy (SMA). The study met its primary endpoint with 29% of infants (12/41) sitting without support for at least five seconds* by month 12, a milestone not seen in the natural course of the disease. Safety for Evrysdi in the FIREFISH Part 2 study was consistent with its known safety profile.“Without treatme...
Source: Roche Media News - July 29, 2021 Category: Pharmaceuticals Source Type: news

Data for Roche ’s Evrysdi® (risdiplam) published in New England Journal of Medicine shows significant improvement in survival and motor milestones in babies with Type 1 spinal muscular atrophy (SMA)
Basel, 29 July 2021 – Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced that the New England Journal of Medicine (NEJM) has published data from FIREFISH Part 2, a pivotal global study evaluating the efficacy and safety of Evrysdi® (risdiplam) in babies aged 1-7 months old with symptomatic Type 1 spinal muscular atr ophy (SMA). The study met its primary endpoint with 29% of infants (12/41) sitting without support for at least five seconds* by month 12, a milestone not seen in the natural course of the disease. Safety for Evrysdi in the FIREFISH Part 2 study was consistent with its known safety profile.“Without treatme...
Source: Roche Investor Update - July 29, 2021 Category: Pharmaceuticals Source Type: news

High-Tech Exoskeletons Improve Bowel Function in People With Spinal Cord Injury
FRIDAY, July 23, 2021 -- Digestive issues are common after spinal cord injury and can lead to chronic constipation and incontinence. But robotic exoskeleton-assisted walking can improve matters in people with such injuries, researchers say. In an... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - July 23, 2021 Category: General Medicine Source Type: news

How to treat constipation: The 11 foods to AVOID when constipated
CONSTIPATION isn't usually anything to worry about and is normally easily fixed, starting with changes to your diet. Here are 11 foods to avoid when constipated. (Source: Daily Express - Health)
Source: Daily Express - Health - July 21, 2021 Category: Consumer Health News Source Type: news

Enulose (Lactulose Solution) - updated on RxList
Enulose (lactulose) Solution is used to treat chronic constipation. Learn side effects, dosage, drug interactions, warnings, patient labeling, reviews, and more. (Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - July 21, 2021 Category: Drugs & Pharmacology Source Type: news