Elobixibat Improves Constipation in Chronic Kidney Disease
MONDAY, March 21, 2022 -- For patients with moderate- to end-stage chronic kidney disease, elobixibat is associated with improvement in constipation and lipid metabolism, according to a study recently published in Frontiers in Medicine. Momoko... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - March 21, 2022 Category: Pharmaceuticals Source Type: news

The Truth About Common Digestive Health Fears
Everyone experiences digestive problems now and then, and they’re nobody’s idea of a good time. In a survey of nearly 72,000 adults in the U.S., 61% reported having had at least one gastrointestinal (GI) symptom over the previous week, and within that group, 58% said they’d had two or more GI symptoms over the past week, according to a study in a 2018 issue of the American Journal of Gastroenterology. Because symptoms like constipation, heartburn, and abdominal pain are generally vague and often don’t have an obvious cause, those suffering tend to fear the worst. “People get very concerned abo...
Source: TIME: Health - March 14, 2022 Category: Consumer Health News Authors: Stacey Colino Tags: Uncategorized healthscienceclimate Source Type: news

What We Know About Leaky Gut Syndrome
Most of your internal organs are comfortably well protected from the outside world. But the gastrointestinal tract—or more precisely, the inside of the gastrointestinal tract—comes in contact with items from the outside world every day. The foods you eat enter the body via the mouth, travel to the stomach, where they’re partially digested, and move on to the intestines, where the real work of extracting the nutrients and energy we need to live and thrive takes place. The system usually works quite well, but for some folks, it can spring leaks—just as any well-used plumbing system might. These tiny l...
Source: TIME: Health - March 9, 2022 Category: Consumer Health News Authors: Elaine K. Howley Tags: Uncategorized healthscienceclimate Source Type: news

What Are the Five Common Causes of Constipation?
Title: What Are the Five Common Causes of Constipation?Category: Diseases and ConditionsCreated: 2/10/2022 12:00:00 AMLast Editorial Review: 3/9/2022 12:00:00 AM (Source: MedicineNet Digestion General)
Source: MedicineNet Digestion General - March 9, 2022 Category: Nutrition Source Type: news

The Mysteries and Underdiagnosis of SIBO
In 2017, shortly after she turned 32, Phoebe Lapine had just spent the previous three years overhauling her health to make up for her ailing thyroid, the result of unchecked Hashimoto’s thyroiditis. She was following a gluten-free diet, drinking kombucha and taking prebiotics, and finally feeling her best when she noticed peculiar gut symptoms starting to rear their head: burping during meals, stomach discomfort, and a bloated belly that simply would not deflate. She turned to a functional doctor who quickly gave her a diagnosis: small intestinal bacterial overgrowth (SIBO), a gut condition not uncommon for hypothyro...
Source: TIME: Health - March 7, 2022 Category: Consumer Health News Authors: Meaghan Beatley Tags: Uncategorized Source Type: news

Markers in Saliva Tied to Gut Disorders in Children With Autism Markers in Saliva Tied to Gut Disorders in Children With Autism
New research opens the door to targeting constipation and other gastrointestinal disorders in children with autism spectrum disorder.Medscape Medical News (Source: Medscape Internal Medicine Headlines)
Source: Medscape Internal Medicine Headlines - March 4, 2022 Category: Internal Medicine Tags: Psychiatry News Source Type: news

U.S. FDA Approves CARVYKTI ™ (ciltacabtagene autoleucel), Janssen’s First Cell Therapy, a BCMA-Directed CAR-T Immunotherapy for the Treatment of Patients with Relapsed or Refractory Multiple Myeloma
HORSHAM, Pa., February 28, 2022 – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today the U.S. Food and Drug Administration (FDA) has approved CARVYKTI™ (ciltacabtagene autoleucel; cilta-cel) for the treatment of adults with relapsed or refractory multiple myeloma (RRMM) after four or more prior lines of therapy, including a proteasome inhibitor, an immunomodulatory agent, and an anti-CD38 monoclonal antibody.1 The approval is based on data from the pivotal CARTITUDE-1 study, which included patients who had received a median of six prior treatment regimens (range, 3-18), and had previously rec...
Source: Johnson and Johnson - March 1, 2022 Category: Pharmaceuticals Tags: Innovation Source Type: news

What Causes Rectal Prolapse?
Discussion Rectal prolapse is defined as a herniation of the rectum through the anal verge. In children it is also usually mucosal prolapse and not full thickness. Partial or mucosal prolapse usually is seen as radial folds occurring 1 – 2.5 cm from the anal verge. Full thickness will protrude more than 5 cm. It affects genders equally and occurs most commonly in children under age 4. This is due to vertical course and low position of the anus, looser supporting tissues and less muscular support. These children are more likely to have prolapse but are less likely to have it recur. After age 4 the rectum takes the adu...
Source: PediatricEducation.org - February 28, 2022 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

What Are the Causes of Constipation?
Title: What Are the Causes of Constipation?Category: Diseases and ConditionsCreated: 2/10/2022 12:00:00 AMLast Editorial Review: 2/10/2022 12:00:00 AM (Source: MedicineNet Digestion General)
Source: MedicineNet Digestion General - February 10, 2022 Category: Nutrition Source Type: news

'Single-handedly one of the main causes': Ease bloating and constipation by tackling habit
BLOATING and constipation often go hand in hand. A gut health expert explain one major habit could be causing or exacerbating both. (Source: Daily Express - Health)
Source: Daily Express - Health - January 31, 2022 Category: Consumer Health News Source Type: news

What Are Common Gastrointestinal Polyposes in Children?
Discussion Bloody stools or blood in the diaper is a relatively common complaint in general pediatrics. For most patients it is often a minor concern. Commonly it is a transient problem (e.g. rectal fissure caused by constipation or trauma) or often not blood (e.g. urate crystals in the diaper, food, menses, etc.). Real blood does occur with an identifiable cause such as long distance running or heavy exercise, or milk protein allergy/sensitivity that improves with a milk-restricted diet. Many more serious causes are associated with heavier or more recalcitrant bleeding, increased defecation, abdominal pain, poor eating an...
Source: PediatricEducation.org - January 24, 2022 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Laxative Use in CKD Patients Transitioning to Dialysis Laxative Use in CKD Patients Transitioning to Dialysis
Prescribed laxatives are often required for managing constipation among CKD patients transitioning to dialysis. A new study examines the prevalence and patterns of its use in this population.Nephrology Dialysis Transplantation (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - December 28, 2021 Category: Consumer Health News Tags: Nephrology Journal Article Source Type: news

Protect gut over Christmas and avoid constipation and bloating with 'fermented foods' list
CONSTIPATION and bloating can be avoided by eating certain foods, including fermented food according to one nutritionist. (Source: Daily Express - Health)
Source: Daily Express - Health - December 26, 2021 Category: Consumer Health News Source Type: news

Dr Zoe Williams shares how ‘squatty potty’ can help with constipation this Christmas
CONSTIPATION is a common problem that can be more prevalent during the Christmas period when we indulge in various festive foods. This Morning's doctor Zoe Williams has shared a simple technique called "squatty potty" to help with this uncomfortable problem. (Source: Daily Express - Health)
Source: Daily Express - Health - December 24, 2021 Category: Consumer Health News Source Type: news

New Data from MajesTEC-1 Study Show Continued Deep and Durable Responses of Teclistamab (BCMAxCD3 Bispecific Antibody) in Treatment of Heavily Pretreated Patients with Multiple Myeloma
The objective responsive rate observed in this study suggests a potential benefit for many patients with triple-class exposed disease with an off-the-shelf therapy.”As of September 2021, 165 patients were treated with teclistamab at the SC 1.5 mg/kg dose across both Phase 1 and Phase 2 of MajesTEC-1.1 The primary objectives of the MajesTEC-1 Phase 1 study (NCT03145181) were to identify the recommended SC RP2D (part 1) and characterize the safety and tolerability of teclistamab at the RP2D (part 2). The primary objective of the MajesTEC-1 Phase 2 study (NCT04557098) was to evaluate the efficacy of teclistamab at the RP2D,...
Source: Johnson and Johnson - December 13, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news