How Common is Recurrent Kawasaki Disease?
Patient Presentation A 3.5-year-old female came to clinic with a 2-day history fever up to 101°F. The evening before she had complained of a sore throat but had no rhinorrhea, cough or rash. She was drinking reasonably well and was urinating frequently. She had been to a birthday party where an older child had had strep throat. The past medical history was positive for Kawasaki Disease diagnosed at 17 months of age and treated with intravenous immunoglobulin (IVIG) on day 6 of fever. Her echocardiograms had been negative and she was being appropriately monitored by cardiology. The family history was positive for heart...
Source: PediatricEducation.org - July 16, 2018 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news
A Diagnostic Dilemma: Sometimes You ’ ll Never Know
Patient Presentation A 9-year-old male came to clinic with a 1 month history of painful joint swelling. One month ago he started having right ankle pain that was intermittent but consistent. One day ago his right wrist, right ankle and bilateral knees had some swelling but no erythema or warmth. He says that he has pain in them when he moves but not when he is resting and he denies any joint stiffness or gelling. He also had 1-2 days of multiple red skin lesions on his extremities and trunk, not overlying the affected joints. The skin lesions do not come and go and do not itch. They are mainly discrete circular lesions wi...
Source: PediatricEducation.org - March 19, 2018 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news
Texas researchers take on mysterious children's illness
(Texas Biomedical Research Institute) Texas Biomedical Research Institute and The Children's Hospital of San Antonio have joined forces to cure a mysterious condition called Kawasaki disease. The illness which affects young children is named after the Japanese doctor who first described it more than 50 years ago. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - February 15, 2018 Category: Infectious Diseases Source Type: news
Title: Kawasaki DiseaseCategory: Diseases and ConditionsCreated: 11/2/1998 12:00:00 AMLast Editorial Review: 11/8/2017 12:00:00 AM (Source: MedicineNet Kids Health General)
Source: MedicineNet Kids Health General - November 8, 2017 Category: Pediatrics Source Type: news
What Causes White Nails?
Discussion The nail matrix covers the area of the nail plate, and extends proximally in a crescent moon shape with the edges of the crescent extending proximally and inferiorly toward the underlying bone. The nail matrix is a multilayered epithelium that physiologically produces keratinization and gives rise to the nail plate. The distal matrix forms the lower 2/3s of the nail plate and the proximal matrix forms the upper 1/3 of the nail plate. the thickness of the nail plate is proportion to the matrix’s thickness. The nail plate’s free edge contour follows the shape of the nail’s lunula. Melanocytes occ...
Source: PediatricEducation.org - November 6, 2017 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news
Back in Kosovo after life-saving surgery, Lis ’s heart remains in Boston
Like many kids, Lis Spahiu loves wearing his Boston Celtics and New England Patriots t-shirts. His mom, Zana, jokes that sometimes she needs to hide them so he’ll wear something else. But Lis isn’t a typical Boston sports fan. This 5-year-old from Kosovo has grown to love Boston, and its sports teams, after several trips to the Boston Children’s Hospital to receive life-saving care for his heart. “In Kosovo, the health care system is very poor,” explains Lis’s mom Zana. “So when Lis contracted Kawasaki disease at 5 months old, he was misdiagnosed.” Kawasaki disease cause...
Source: Thrive, Children's Hospital Boston - October 6, 2017 Category: Pediatrics Authors: Ellen Greenlaw Tags: Diseases & Conditions Our Patients’ Stories Coronary Artery Program Dr. Jane Newburger Dr. Luis Quinonez Kawasaki disease Kawasaki Disease Program Source Type: news
Kawasaki Disease: High- or Low-Dose Aspirin? Kawasaki Disease: High- or Low-Dose Aspirin?
Which approach is best in preventing coronary artery abnormalities in children with Kawasaki disease?Medscape Pediatrics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 12, 2017 Category: Consumer Health News Tags: Pediatrics Viewpoint Source Type: news
Prompt Diagnosis, Careful Follow-up Essential for Kawasaki Disease Prompt Diagnosis, Careful Follow-up Essential for Kawasaki Disease
Effective management of Kawasaki disease requires a prompt diagnosis and careful follow-up, according to an updated scientific statement from the American Heart Association.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - April 17, 2017 Category: Consumer Health News Tags: Internal Medicine News Source Type: news
Mother of baby with meningitis told she had chickenpox
Tiffany Staveley, 26, was given calamine lotion to treat her daughter, Ava. The five-month-old was found to have both meningitis and Kawasaki disease, and was taken to Leeds General Infirmary. (Source: the Mail online | Health)
Source: the Mail online | Health - March 17, 2017 Category: Consumer Health News Source Type: news
Gene variant identified for Kawasaki disease susceptibility
(University of California - San Diego) Researchers at University of California San Diego School of Medicine, with colleagues at Rady Children's Institute for Genomic Medicine and in London and Singapore, have conducted novel whole genome sequencing of a family in which two of four children were affected by Kawasaki disease. They have identified plausible gene variants that predispose some children to developing the disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 9, 2017 Category: Global & Universal Source Type: news
UC San Diego researcher to study most effective treatment for Kawasaki disease
(University of California - San Diego) Researchers at University of California San Diego School of Medicine, Rady Children's Hospital-San Diego and Betty Irene Moore School of Nursing at University of California Davis have received a $2 million grant from the Patient-Centered Outcomes Research Institute (PCORI) for a three-year study to look at the effectiveness of two treatment options for children with KD who are resistant to initial therapy. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 2, 2017 Category: Global & Universal Source Type: news
Giving thanks: Stories of volunteerism, gratitude and giving back
Thanksgiving Day is a time rich in family, gratitude and appreciation. In honor of the holiday, we are celebrating the patient families who have traveled through our doors and the selfless acts of kindness and volunteerism that follow. Donating platelets and cycling for a cause Ten years ago, Adam Nussenbaum’s son Max was treated at Boston Children’s and overcame a life threatening illness. Today, Adam gives his time — and platelets — to help those in need, and he is doing so in celebration of Max; his daughter Kate, who donated her bone marrow to he...
Source: Thrive, Children's Hospital Boston - November 24, 2016 Category: Pediatrics Authors: Maureen McCarthy Tags: Our Patients’ Stories bone marrow transplant cerebral palsy Dr. James Kasser Family Advisory Council Heart Center Kawasaki disease Learning disabilities NICU patient partner platelet donation scoliosis Source Type: news
Psoriasiform eruptions in Kawasaki disease reveal distinct phenotype
A comparison of psoriasis-like eruptions in Kawasaki disease (KD) with classic psoriasis shows a distinct phenotype with greater remission, report Ellen S. Haddock, AB, MBA and coauthors from the School of Medicine at the University of California, San Diego. Investigators performed a retrospective... (Source: Skin and Allergy News)
Source: Skin and Allergy News - July 21, 2016 Category: Dermatology Source Type: news
Thomas’ story: Overcoming Kawasaki, a rare pediatric heart disease
Thomas after his second round of treatment for Kawasaki It took three trips to the doctor’s office and consults with four different providers for Valerie Flynn to finally get to the bottom of her son’s suffering. Thomas’s confluence of symptoms was puzzling: a high fever that wouldn’t go away for five days, all-over itchiness with a head-to-toe rash; bloodshot eyes and absolute exhaustion. “Thomas’ doctors kept telling me it must be a virus and to give him Benadryl for the itch and Tylenol for the fever, but those did nothing to help,” says Valerie. “That&...
Source: Thrive, Children's Hospital Boston - May 24, 2016 Category: Pediatrics Authors: Erin Horan Tags: Diseases & Conditions Annette Baker Dr. Jane Newburger Heart Center Kawasaki Disease Program Source Type: news
Kawasaki disease and infections aren’t mutually exclusive
CHICAGO – Kawasaki disease and concurrent bacterial or viral infection are by no means mutually exclusive, Dr. Cathie-Kim Le cautioned at the annual meeting of the American College of Cardiology.... (Source: Pediatric News)
Source: Pediatric News - May 1, 2016 Category: Journals (General) Source Type: news
Evidence of a respiratory virus does not exclude Kawasaki disease
Many children with Kawasaki disease (KD) have respiratory viruses and a positive viral polymerase chain reaction should not exclude a KD diagnosis, according to a new study. Kawasaki disease is a major cause of heart disease in children, however a specific etiology has yet to be found. A viral... (Source: Skin and Allergy News)
Source: Skin and Allergy News - August 24, 2015 Category: Dermatology Source Type: news
What Are Common Drug Eruptions in Children?
Patient Presentation A 4-year-old female came to clinic because of a rash for 24 hours. The pruritic rash began the evening before with a few red spots on her trunk. She had slept well, but this morning they were spreading and enlarging in size on her trunk, neck and extremities and did not seem to come and go. She also had a fever and her mother thought that she wasn’t moving as well and seemed to be sore. The patient had been started on cefaclor 9 days earlier for an ear infection and upper respiratory tract infection symptoms. She had previously taken penicillins and cephalosporin antibiotics without any problems...
Source: PediatricEducation.org - July 27, 2015 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news
9 Childhood Illnesses: Get the Facts
WebMD shares facts on 9 childhood illnesses you may not know about: RSV, fifth disease, croup, scarlet fever, impetigo, Kawasaki disease, Reye's syndrome, whooping cough, and hand, foot, and mouth disease. (Source: WebMD Health)
Source: WebMD Health - July 25, 2015 Category: Consumer Health News Source Type: news
Adult Kawasaki Disease in a European PatientAdult Kawasaki Disease in a European Patient
While Kawasaki disease is usually diagnosed in Asian children, this case demonstrates it should be considered in cases of prolonged fever without response to antibiotics, even in non-Asian adults. Journal of Medical Case Reports (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 3, 2015 Category: Consumer Health News Tags: Family Medicine/Primary Care Journal Article Source Type: news
Pegasus Therapeutics looks to Indiegogo for pediatric aneurysm device
Pegasus Therapeutics looks to crowd-fund for a benchtop model of its stent-like device to treat pediatric aneurysms caused by Kawasaki disease. Boston startup Pegasus Therapeutics is using crowdfunding site Indiegogo to solicit money for the development of a stent-like device designed to treat pediatric patients with coronary artery aneurysms. Indiegogo, Pegasus TherapeuticsNews Well, Cardiovascular, Funding Roundup, Pediatricsread more (Source: Mass Device)
Source: Mass Device - March 16, 2015 Category: Medical Equipment Authors: Mark Hollmer Source Type: news
Child's rare disease journey inspires medical device startup
By the time Aubry Shackelford's five-year-old daughter was diagnosed with Kawasaki Disease, the virus had already extensively damaged her heart. The disease, which affects an estimated 4,000 US children under the age of five annually, causes inflammation in the walls of medium-sized arteries throughout the body. For Shackelford's daughter, Allison Shachelford, and for potentially thousands of others who don't receive the right diagnosis in time, the disease left two giant aneurisms in her right… (Source: bizjournals.com Health Care:Physician Practices headlines)
Source: bizjournals.com Health Care:Physician Practices headlines - March 16, 2015 Category: American Health Authors: Jessica Bartlett Source Type: news
What Causes Vesicular Exanthams?
Discussion Vesicles are circumscribed, elevated, fluid-filled lesions 1 cm and often easily rupture due to their thin walls. The differential diagnosis is different for bullae than for vesicular lesions and is often more ominous including such diseases as Steven-Johnson, staphylococcal scalded skin and meningococcemia. Vesicular or bullous exanthems should be investigated more extensively if there is skin sloughing, petechiae or purpura, fever and irritability, inflammation of the mucosa, urticaria, has respiratory distress, and diarrhea or abdominal pain. Learning Point The differential diagnosis for vesicular exanthems ...
Source: PediatricEducation.org - March 2, 2015 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news
Revised Article-Kawasaki Disease
Kawasaki disease is a rare childhood disease. It is a form of a condition called vasculitis. This condition involves inflammation of the blood vessels. (Source: National Heart, Lung, and Blood Institute Health Topics)
Source: National Heart, Lung, and Blood Institute Health Topics - October 27, 2014 Category: Consumer Health News Source Type: news
Recognizing and treating an atypical case of Kawasaki disease
It was a Saint Paddy’s Day that Jake and his mother, Nancy O’Connor, will never forget. While everyone else was sporting green, Jake’s skin and tongue started turning red, and the whites of his eyes eventually turned yellow. It was a medical problem that eventually led him to Boston Children’s Hospital where he was diagnosed with an atypical case of Kawasaki disease, a rare condition that can cause a rash, red eyes and mouth, and other inflammatory symptoms. Most importantly, Kawasaki disease can lead to serious complications of the heart, especially if not treated in time. Difficult diagnosis...
Source: Thrive, Children's Hospital Boston - May 28, 2014 Category: Pediatrics Authors: Tripp Underwood Tags: All posts Heart Center Jane Newburger Kawasaki disease Kawasaki Disease Program our patients' stories Source Type: news
Mysterious Illness May Be Carried by the Wind
Meteorological patterns suggest crop fungus may cause Kawasaki disease (Source: ScienceNOW)
Source: ScienceNOW - May 19, 2014 Category: Science Source Type: news
Possible cause and source of Kawasaki disease found
(University of California - San Diego) An international team of scientists, including researchers from the University of California, San Diego, report that the likely causative agent of Kawasaki disease (KD) in Japan is a windborne agent originating from a source in northeast China. KD is a mysterious childhood ailment that can permanently damage coronary arteries. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - May 19, 2014 Category: Infectious Diseases Source Type: news
Pregnancy risks for women with Kawasaki disease are manageable, provided doctors recognize them
In the first study of its type, researchers at the University of California, San Diego School of Medicine have looked at the health threat to pregnant women with a history of Kawasaki disease (KD), concluding that the risks are low with informed management and care.The findings are published in the online edition of the British Journal of Obstetrics and Gynaecology.KD is a childhood condition affecting the coronary arteries. It is the most common cause of acquired heart disease in children. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - March 11, 2014 Category: Consumer Health News Tags: Heart Disease Source Type: news
Kawasaki disease and pregnant women
(University of California - San Diego) In the first study of its type, researchers at the University of California, San Diego School of Medicine have looked at the health threat to pregnant women with a history of Kawasaki disease, concluding that the risks are low with informed management and care. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 6, 2014 Category: Global & Universal Source Type: news
Role of infliximab examined in treating Kawasaki disease
A new study has looked at intensification of initial therapy for all children with Kawasaki Disease in order to prevent IVIG-resistance and associated coronary artery abnormalities by assessing the addition of the medication infliximab to current standard therapy. Kawasaki Disease is a severe childhood disease that many parents, even some doctors, mistake for an inconsequential viral infection. If not diagnosed or treated in time, it can lead to irreversible heart damage. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - February 24, 2014 Category: Science Source Type: news
Molecular researchers find new key to inflammatory diseases
Biologists have discovered genetic material that may help to explain part of how our immune defense is triggered. Dubbing it THRIL, they say it could be targeted in the development of treatments against inflammatory diseases such as Kawasaki disease, rheumatoid arthritis and inflammatory bowel disease.The researchers have discovered a new molecule that forms when the immune response is triggered by pathogens - disease-causing bacteria and viruses. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - December 30, 2013 Category: Consumer Health News Tags: Immune System / Vaccines Source Type: news
Discovering a 'THRIL' that correlates with severity of Kawasaki disease
(Sanford-Burnham Medical Research Institute) A newly identified RNA-protein complex controls TNF-alpha expression -- suggesting that it plays a key role in inflammatory immune responses. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 26, 2013 Category: Global & Universal Source Type: news
Well: Think Like a Doctor: Eyes Solved
The cause of Kawasaki disease is still unknown, but the thinking these days is that it is an unusual immune response to a probable viral infection in children who have some kind of genetic predisposition to it. (Source: NYT Health)
Source: NYT Health - December 6, 2013 Category: Consumer Health News Authors: By LISA SANDERS, M.D. Tags: Eyes and Eyesight Doctors Babies and Infants Think Like a Doctor medicine and health Featured Nursing and Nurses Source Type: news
Massachusetts hospital and Abwiz to develop diagnostic tool for KD
Boston Children's Hospital, a 395-bed hospital in the Longwood Medical and Academic Area of Boston, Massachusetts, has signed a partnership agreement with Abwiz Bio to develop a prototype test kit to diagnose Kawasaki Disease (KD). (Source: Hospital Management)
Source: Hospital Management - October 28, 2013 Category: Hospital Management Source Type: news
Comprehensive analysis to detect seasonal cycles of Kawasaki disease season to isolate cause of devastating childhood disease
After more than four decades of research, strong evidence now shows that Kawasaki disease has a distinct seasonal occurrence shared by regions across the Northern hemisphere. The first global analysis of the seasonality of Kawasaki disease, published by PLOS ONE, was carried out using data obtained between 1970 and 2012. It included 296,203 cases from 39 locations in 25 countries around the globe, with 27 of those locations in the extra-tropical Northern hemisphere, eight in the tropics, and four in the extra-tropical Southern hemisphere... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - September 26, 2013 Category: Consumer Health News Tags: Infectious Diseases / Bacteria / Viruses Source Type: news
Data from across globe defines distinct Kawasaki disease season
(University of California - San Diego) After more than four decades of research, strong evidence now shows that Kawasaki disease has a distinct seasonal occurrence shared by regions across the Northern hemisphere. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 23, 2013 Category: Global & Universal Source Type: news
Echocardiographic Findings in a Child Allergic to Cow's MilkEchocardiographic Findings in a Child Allergic to Cow's Milk
A 9-month-old child presented with several clinical features of Kawasaki disease, together with mild cardiac echocardiographic alterations, but no fever. What was the cause? Journal of Medical Case Reports (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 4, 2013 Category: Consumer Health News Tags: Allergy & Clinical Immunology Journal Article Source Type: news
What is Acute Hemorrhagic Edema of Infancy?
Discussion The differential diagnosis for acute hemorrhagic edema of infancy (AHEI) is similar to purpura and includes: Vascultitis Henoch-Schonlein purpura (HSP) Drug induced Kawasaki disease Rocky Mountain Spotted Fever Trauma induced Infectious Disease Meningococcemia Sepsis Dermatologic Erythema multiforme Gianotti Crosti Hemorrhagic urticaria Sweet’s syndrome Child maltreatment Neonatal lupus Learning Point Acute hemorrhagic edema of infancy (AHEI, also called Seidlmayer or postinfectious cockade purpura, medallion-like purpura, or Finkelstein’s disease) is an uncommon, self-limited cutaneous leukocy...
Source: PediatricEducation.org - January 28, 2013 Category: Pediatrics Authors: Donna M. D'Alessandro, M.D. Tags: Uncategorized Source Type: news
Contemporary Pediatrics Digital Edition - December 2012
Kawasaki Disease : Early Diagnosis Essential (Source: Modern Medicine Contemporary Pediatrics)
Source: Modern Medicine Contemporary Pediatrics - December 1, 2012 Category: Pediatrics Source Type: news