Pediatric Sepsis in the Time of Coronavirus Disease 2019
The volume of data and studies on coronavirus disease 2019 (COVID-19) disease caused by the novel coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has grown at a pace as unprecedented as the pandemic itself. Statistics and findings change weekly. Although pediatric cases have thankfully remained a small minority (1.7 –2%) of overall worldwide COVID-19 cases (2), the potential for severe illness in children remains and grows. Rapidly published pediatric case series have identified severe critical COVID-19–related illnesses associated with primary SARS-CoV-2 infection and findings consistent with ...
Source: Current Awareness Service for Health (CASH) - December 10, 2020 Category: Consumer Health News Source Type: news
Kids' Severe COVID-19 Reaction Bears Unique Immune Signature
The rare complication known as multisystem inflammatory syndrome in children (MIS-C) differs from both Kawasaki disease and severe adult cases of COVID-19, a study finds. (Source: The Scientist)
Source: The Scientist - September 29, 2020 Category: Science Tags: News & Opinion Source Type: news
CHOP researchers find MIS-C associated with myocardial injury
(Children's Hospital of Philadelphia) Using sensitive parameters to assess cardiac function, researchers at Children's Hospital of Philadelphia (CHOP) have found that cardiac involvement in multisystem inflammatory syndrome in children (MIS-C) differs from Kawasaki disease (KD) and is associated with myocardial injury. The findings were published recently in the Journal of the American College of Cardiology. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - September 21, 2020 Category: Infectious Diseases Source Type: news
Corticosteroids Appear to Stop Abnormalities in Kawasaki Disease Corticosteroids Appear to Stop Abnormalities in Kawasaki Disease
Addition of corticosteroids to initial intravenous immunoglobulin treatment appears to reduce the rate of coronary-artery abnormalities in high-risk patients with Kawasaki disease.Reuters Health Information (Source: Medscape Radiology Headlines)
Source: Medscape Radiology Headlines - August 21, 2020 Category: Radiology Tags: Cardiology News Source Type: news
Combination Therapy May Benefit Some With Kawasaki Disease
WEDNESDAY, Aug. 19, 2020 -- Adding corticosteroids to initial intravenous immunoglobulin seems beneficial for preventing coronary artery abnormalities in high-risk patients with Kawasaki disease (KD), according to a study published online Aug. 19 in... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - August 19, 2020 Category: Pharmaceuticals Source Type: news
Combo therapy may prevent blood vessel complications in children with Kawasaki disease
(American Heart Association) For children with Kawasaki disease with higher risk of developing blood vessel complications, adding corticosteroids to standard intravenous immunoglobulin treatment could boost initial treatment response and prevent complications.Researchers used real-world data from large, nationwide Japanese Kawasaki disease surveys to compare combination therapy with the standard treatment. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 19, 2020 Category: International Medicine & Public Health Source Type: news
Coronavirus triggers inflammatory condition MIS-C in children
Researchers at King's College London discovered the illness, known as multisystem inflammatory syndrome in children (MIS-C), is unique and different to COVID-19 and Kawasaki Disease. (Source: the Mail online | Health)
Source: the Mail online | Health - August 18, 2020 Category: Consumer Health News Source Type: news
Hispanic, Black children at higher risk of coronavirus-related hospitalization, CDC finds
The syndrome known as MIS-C, which in some cases mirrors the symptoms of Kawasaki disease, is thought to be triggered by exposure to the virus. (Source: Washington Post: To Your Health)
Source: Washington Post: To Your Health - August 8, 2020 Category: Consumer Health News Authors: Chelsea Janes Source Type: news
CHOP researchers identify lab profiles that differentiate MIS-C from COVID-19 in children
(Children's Hospital of Philadelphia) Researchers from Children's Hospital of Philadelphia (CHOP) report important data that differentiate MIS-C from severe COVID-19 in children and suggest that MIS-C is a post-infectious syndrome related to COVID-19 but distinct from Kawasaki disease. The findings were published today in The Journal of Clinical Investigation. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 30, 2020 Category: International Medicine & Public Health Source Type: news
COVID-19: paediatric surveillance, PHE (updated 28th July 2020)
Children represent a small proportion of the total number of confirmed cases, with older adults and those with underlying co-morbidities particularly affected by the current global pandemic. Whilst this is reassuring for paediatricians, there are limited data on childhood SARS-CoV-19 infections, especially from Europe.
28 July 2020 Added updated sKIDs protocol. 12 June 2020 Added studies 5 to 7: RAPID-19 study; sKIDs COVID-19 surveillance in school children; and Multi-system inflammatory syndrome, Kawasaki disease and toxic shock syndrome. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - July 28, 2020 Category: Consumer Health News Source Type: news
Coronavirus-Related Illness Linked To At Least 285 Children In US
(AP) – At least 285 U.S. children have developed a serious inflammatory condition linked to the coronavirus and while most recovered, the potential for long-term or permanent damage is unknown, two new studies suggest.
The papers, published online Monday in the New England Journal of Medicine, provide the fullest report yet on the condition.
The condition is known as multisystem inflammatory syndrome in children. It is considered uncommon and deaths are rare; six children died among the 285 in the new studies.
Including cases in Europe, where it was first reported, about 1,000 children worldwide have been affected, a...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - June 30, 2020 Category: Consumer Health News Authors: Health – CBS Boston Tags: Boston News Covid-19 Boston, MA Health Healthcare Status Syndicated CBSN Boston Coronavirus Source Type: news
Caring for Children With Multisystem Inflammatory Syndrome
Now, nearly two months after the first cases were reported, doctors can reassure parents that the syndrome remains rare, while continuing to urge vigilance. (Source: NYT Health)
Source: NYT Health - June 29, 2020 Category: Consumer Health News Authors: Perri Klass, M.D. Tags: Children and Childhood Pediatric Inflammatory Multisystem Syndrome (PIMS) Coronavirus (2019-nCoV) Kawasaki Disease Immune System Journal of the American Medical Assn Mount Sinai Medical Center Source Type: news
Most Kids Do Not Get Severe COVID-19, Large Study Confirms
A large European study confirms a rare bit of good news about COVID-19: children seem to be mostly spared from the worst of its effects.
The paper, published June 25 in the Lancet Child & Adolescent Health, suggests well fewer than 1% of children who develop COVID-19 will go on to die from it, and the vast majority will not need intensive care. By contrast, in some of the world’s hardest-hit countries, case fatality ratios that include adults are estimated (albeit using preliminary data) to be higher than 10%.
The new study analyzed case data from almost 600 pediatric COVID-19 patients from 21 different European...
Source: TIME: Health - June 25, 2020 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized COVID-19 Source Type: news
Dr. Tomisaku Kawasaki, Who Pinpointed a Mysterious Disease, Dies at 95
In 1967, he identified a disease that causes heart inflammation in children, one that Covid-19 has brought back into the news. (Source: NYT Health)
Source: NYT Health - June 17, 2020 Category: Consumer Health News Authors: Neil Genzlinger Tags: Kawasaki Disease Pediatric Inflammatory Multisystem Syndrome (PIMS) Deaths (Obituaries) Kawasaki, Tomisaku Coronavirus (2019-nCoV) Source Type: news
AHA News: Doctor Who Discovered Kawasaki Disease Dead at 95
Title: AHA News: Doctor Who Discovered Kawasaki Disease Dead at 95Category: Health NewsCreated: 6/11/2020 12:00:00 AMLast Editorial Review: 6/12/2020 12:00:00 AM (Source: MedicineNet Heart General)
Source: MedicineNet Heart General - June 12, 2020 Category: Cardiology Source Type: news
