Mortality rate after total knee arthroplasty or total hip arthroplasty in patients with a history of liver transplant
World J Orthop. 2024 Apr 18;15(4):310-311. doi: 10.5312/wjo.v15.i4.310. eCollection 2024 Apr 18.ABSTRACTIn this editorial I comment on the article by Ahmed et al published in a recent issue of the World J Orthop 2023; 14: 784-790. It is well known that patients who have undergone a liver transplant (LT) may need to have a total hip arthroplasty (THA) or total knee arthroplasty (TKA) implanted. Ahmed et al stated that the mortality rate in these patients was similar to the one of the general population. However, there are three articles previously published that found higher mortality in LT patients who experienced THA/TKA ...
Source: World Journal of Orthopaedics - April 29, 2024 Category: Orthopaedics Authors: E Carlos Rodriguez-Merchan Source Type: research
Results of Autologous Hematopoietic Stem Cell Transplantation in Patients with Multiple Myeloma(MM) and Renal Impairment: A Retrospective Single-Center Study
Conclusion: Auto-HSCT is a safe and effective treatment for patients with MM complicated by acute kidney injury. Fourteen of 23 (61%) patients became dialysis-independent.PMID:38680711 | PMC:PMC11055427 | DOI:10.18502/ijhoscr.v18i1.14745 (Source: Herpes)
Source: Herpes - April 29, 2024 Category: Infectious Diseases Authors: Maiia Soloveva Maxim Solovev Daria Mironova Larisa Mendeleeva Source Type: research
Current status of liver transplantation for human immunodeficiency virus-infected patients in mainland China
This study provides an overview of the current landscape of HIV-positive patients receiving liver transplantation (LT) in mainland China. To date, our transplant center has conducted LT for eight end-stage liver disease patients co-infected with HIV, and all but one, who died two months postoperatively due to sepsis and progressive multi-organ failure, have survived. Comparative analysis with hepatitis B virus-infected patients during the same period revealed no statistically significant differences in acute rejection reactions, cytomegalovirus infection, bacteremia, pulmonary infections, acute kidney injury, new-onset can...
Source: World Journal of Gastroenterology - April 29, 2024 Category: Gastroenterology Authors: Jian-Xin Tang Dong Zhao Source Type: research
Effect of pre-transplantation use of angiotensin-converting enzyme inhibitor or angiotensin receptor blocker in kidney transplant recipients-propensity score-matched analysis
CONCLUSIONS: In KT, the preoperative use of ACEi/ARBs did not significantly affect clinical outcomes including delayed graft function, postoperative renal function, hyperkalemia events, incidence of rejection, and graft survival rates compared to the patients who did not receive ACEi/ARBs.PMID:38684638 | DOI:10.1007/s40620-024-01938-3 (Source: Journal of Nephrology)
Source: Journal of Nephrology - April 29, 2024 Category: Urology & Nephrology Authors: Jaeyun Lee Chan-Young Jung Hyosang Kim Hwa Jung Kim Youngmin Ko Hyunwook Kwon Sung Shin Young Hoon Kim Su-Kil Park Chung Hee Baek Source Type: research
Acute respiratory failure due to pulmonary exacerbation in children with cystic fibrosis admitted in a pediatric intensive care unit: outcomes and factors associated with mortality
CONCLUSION: Children with CF admitted to PICU for acute respiratory failure secondary to pulmonary exacerbations are at high risk of death, both in the short and medium terms. Lung transplant is their main chance of survival and should be considered early.PMID:38685088 | DOI:10.1186/s12931-024-02778-2 (Source: Respiratory Care)
Source: Respiratory Care - April 29, 2024 Category: Respiratory Medicine Authors: David Drummond Charlotte Roy Matthieu Cornet Julie Bucher V éronique Boussaud Fran çoise Le Pimpec-Barthes Margaux Pontailler Olivier Raisky Vanessa Lopez Claudio Barbanti Romain Guillemain Sylvain Renolleau Marion Grimaud Mehdi Oualha Laure de Saint Bl Source Type: research
Current status of liver transplantation for human immunodeficiency virus-infected patients in mainland China
This study provides an overview of the current landscape of HIV-positive patients receiving liver transplantation (LT) in mainland China. To date, our transplant center has conducted LT for eight end-stage liver disease patients co-infected with HIV, and all but one, who died two months postoperatively due to sepsis and progressive multi-organ failure, have survived. Comparative analysis with hepatitis B virus-infected patients during the same period revealed no statistically significant differences in acute rejection reactions, cytomegalovirus infection, bacteremia, pulmonary infections, acute kidney injury, new-onset can...
Source: World Journal of Gastroenterology : WJG - April 29, 2024 Category: Gastroenterology Authors: Jian-Xin Tang Dong Zhao Source Type: research
Results of Autologous Hematopoietic Stem Cell Transplantation in Patients with Multiple Myeloma(MM) and Renal Impairment: A Retrospective Single-Center Study
Conclusion: Auto-HSCT is a safe and effective treatment for patients with MM complicated by acute kidney injury. Fourteen of 23 (61%) patients became dialysis-independent.PMID:38680711 | PMC:PMC11055427 | DOI:10.18502/ijhoscr.v18i1.14745 (Source: Cell Research)
Source: Cell Research - April 29, 2024 Category: Cytology Authors: Maiia Soloveva Maxim Solovev Daria Mironova Larisa Mendeleeva Source Type: research
Regarding the role of post-transplant inflammatory cytokine signature on predicting tumor recurrence after liver transplantation for hepatocellular carcinoma
(Source: Hepatology International)
Source: Hepatology International - April 29, 2024 Category: Infectious Diseases Source Type: research
Viruses, Vol. 16, Pages 709: COVID-19 in Lung Transplant Recipients: A Report on 10 Recent Cases
oczulla
Due to immunosuppression, transplant recipients are at higher risk of infections with SARS-CoV-2 and worse clinical outcomes than immunocompetent hosts. Furthermore, lung transplant patients represent a special group among solid organ recipients, since pneumonia is the main manifestation of COVID-19. However, data on the course of disease and the changes in morbidity and mortality during the course of the pandemic are limited. In our pulmonary rehabilitation clinic, we treat patients shortly after lung transplant as well as long-term transplant patients. Over the last almost 4 years of pandemic, we witnessed se...
Source: Viruses - April 29, 2024 Category: Virology Authors: Lea Reemann Nikolaus Kneidinger Bernd Sczepanski Andreas Rembert Koczulla Tags: Case Report Source Type: research
Assessment of biological organ age using molecular pathology in pre-transplant kidney biopsies.
Organ shortage is a major challenge in kidney transplantation but the use of older donors, often with co-morbidities, is hampered by inconsistent outcomes. Methods of accurately stratifying marginal donor organs by clinical and histological assessment are lacking. To better understand organ variability, we profiled the transcriptomes of 271 kidneys from deceased donors at retrieval. Following correction for biopsy composition, we assessed molecular pathways that associated with delayed, and sub-optimal one-year graft function. (Source: Kidney International)
Source: Kidney International - April 29, 2024 Category: Urology & Nephrology Authors: Roy Zhang, Patrick B. Trotter, James McCaffrey, Rory Fitzroy, Giorgio Trivioli, Benjamin J. Stewart, John R. Ferdinand, Kevin W. Loudon, Alexandra Riding, Jonathan West, Ashley Ferro, Menna R. Clatworthy Tags: basic research Source Type: research
Prognostic Value of RV Function Analysis During the Interstage Period in Patients with Hypoplastic Left Heart Syndrome
AbstractCardiac dysfunction is associated with mortality in children with hypoplastic left heart syndrome (HLHS). We evaluated the ability of qualitative and quantitative RV functional parameters to predict outcomes in HLHS patients. In this retrospective, single-center study, echocardiograms from 3 timepoints (pre-stage 1 palliation, 4 –8 weeks post-stage 1 palliation, and pre-Glenn) were analyzed in infants with HLHS. Patients were stratified into two groups based on outcome of transplant-free survival post-Glenn (survivors) versus mortality or transplantation prior to Fontan (non-survivors). Images were retrospective...
Source: Mammalian Genome - April 28, 2024 Category: Genetics & Stem Cells Source Type: research
Potential biomarkers for immune monitoring after renal transplantation
Transpl Immunol. 2024 Apr 26:102046. doi: 10.1016/j.trim.2024.102046. Online ahead of print.ABSTRACTRenal transplantation represents the foremost efficacious approach for ameliorating end-stage renal disease. Despite the current state of advanced renal transplantation techniques and the established postoperative immunosuppression strategy, a subset of patients continues to experience immune rejection during both the early and late postoperative phases, ultimately leading to graft loss. Consequently, the identification of immunobiomarkers capable of predicting the onset of immune rejection becomes imperative in order to fac...
Source: Transplant Immunology - April 28, 2024 Category: Transplant Surgery Authors: Xiaoyu Xu Yi Chen Luyue Kong Xianduo Li Dongdong Chen Zhe Yang Jianning Wang Source Type: research
The predictors and risk factors of two-year rejection in renal transplant patients: A multicenter case-control study
CONCLUSION: Our findings emphasize the need for appropriate prevention and management of infections following kidney transplantation to avoid more serious problems, such as rejection, which could significantly raise the likelihood of allograft failure and probably death. Further studies with larger sample size are needed to investigate the impact of serum chloride levels prior to transplant and intraoperative hypotension on the risk of rejection.PMID:38679014 | DOI:10.1159/000538963 (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - April 28, 2024 Category: Urology & Nephrology Authors: Maram M Alsulami Nouf E Al-Otaibi Walaa A Alshahrani Abdulrahman Altheaby Khalefa M Al Thiab Lina I Alnajjar Mohamed A Albekery Reem F Almutairy Mohammed Y Asiri Sumaya N AlMohareb Faisal Aqeel Alsehli Alanoud T Binthuwaini Alaa Almagthali Sarah S Alwaily Source Type: research
Potential biomarkers for immune monitoring after renal transplantation
Transpl Immunol. 2024 Apr 26:102046. doi: 10.1016/j.trim.2024.102046. Online ahead of print.ABSTRACTRenal transplantation represents the foremost efficacious approach for ameliorating end-stage renal disease. Despite the current state of advanced renal transplantation techniques and the established postoperative immunosuppression strategy, a subset of patients continues to experience immune rejection during both the early and late postoperative phases, ultimately leading to graft loss. Consequently, the identification of immunobiomarkers capable of predicting the onset of immune rejection becomes imperative in order to fac...
Source: Transplant Immunology - April 28, 2024 Category: Transplant Surgery Authors: Xiaoyu Xu Yi Chen Luyue Kong Xianduo Li Dongdong Chen Zhe Yang Jianning Wang Source Type: research
The predictors and risk factors of two-year rejection in renal transplant patients: A multicenter case-control study
CONCLUSION: Our findings emphasize the need for appropriate prevention and management of infections following kidney transplantation to avoid more serious problems, such as rejection, which could significantly raise the likelihood of allograft failure and probably death. Further studies with larger sample size are needed to investigate the impact of serum chloride levels prior to transplant and intraoperative hypotension on the risk of rejection.PMID:38679014 | DOI:10.1159/000538963 (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - April 28, 2024 Category: Urology & Nephrology Authors: Maram M Alsulami Nouf E Al-Otaibi Walaa A Alshahrani Abdulrahman Altheaby Khalefa M Al Thiab Lina I Alnajjar Mohamed A Albekery Reem F Almutairy Mohammed Y Asiri Sumaya N AlMohareb Faisal Aqeel Alsehli Alanoud T Binthuwaini Alaa Almagthali Sarah S Alwaily Source Type: research
