Glutamine supplementation improves the activity and immunosuppressive action of induced regulatory T cells in vitro and in vivo
CONCLUSION: Glutamine supplementation can improve the activity and immunosuppressive action of iTregs, and the possible mechanisms by which this occurs are related to cell proliferation, apoptosis, and OXPHOS.PMID:38663757 | DOI:10.1016/j.trim.2024.102044 (Source: Transplant Immunology)
Source: Transplant Immunology - April 25, 2024 Category: Transplant Surgery Authors: Li Zhang Zhongya Xu Yuanjiu Li Ke-Jia Wu Chongyuan Yu Wenjie Zhu Dong-Lin Sun Li Zhu Jun Zhou Source Type: research
Borderline rejection: To treat or not to treat?
CONCLUSION: Our preliminary study supports the indication for the treatment of acute borderline TCMR only in cases with biopsies confirmed by clinical indication.PMID:38641147 | DOI:10.1016/j.trim.2024.102047 (Source: Transplant Immunology)
Source: Transplant Immunology - April 19, 2024 Category: Transplant Surgery Authors: Alessandra Palmisano Marta D'Angelo Ilaria Gandolfini Marco Delsante Giovanni Maria Rossi Micaela Gentile Enrico Fiaccadori Paolo Cravedi Umberto Maggiore Source Type: research
Early recovery of natural killer cells post T-cell depleted allogeneic stem cell transplantation using alemtuzumab "in the bag"
CONCLUSION: This study of ex vivo T-cell depleted SCT's demonstrates that NK cells recover quicker when compared to those receiving unfractionated grafts. These results may have implications for GvHD and the GvL effect which warrants further study.PMID:38641148 | DOI:10.1016/j.trim.2024.102045 (Source: Transplant Immunology)
Source: Transplant Immunology - April 19, 2024 Category: Transplant Surgery Authors: Glenda M Davison Jessica J Opie Saarah F G Davids Rygana Mohammed Nicolas Novitzky Source Type: research
Beyond prevention: Unveiling the benefits of triple vaccination on COVID-19 severity and resource utilization in solid organ transplant recipients
CONCLUSION: In solid organ transplant recipients with COVID-19, triple vaccination, but not double vaccination, against SARS-CoV-2 was associated with significantly less hospital resource utilization, decreased disease severity, and fewer short-term complications. These real-world data from extensively matched controls support the protective effects of COVID-19 vaccination with boosters in this vulnerable population.PMID:38641149 | DOI:10.1016/j.trim.2024.102048 (Source: Transplant Immunology)
Source: Transplant Immunology - April 19, 2024 Category: Transplant Surgery Authors: Jared R Zhang John C Johnson Richard G Preble Muhammad Mujtaba A Scott Lea Heather L Stevenson Michael Kueht Source Type: research
Borderline rejection: To treat or not to treat?
CONCLUSION: Our preliminary study supports the indication for the treatment of acute borderline TCMR only in cases with biopsies confirmed by clinical indication.PMID:38641147 | DOI:10.1016/j.trim.2024.102047 (Source: Transplant Immunology)
Source: Transplant Immunology - April 19, 2024 Category: Transplant Surgery Authors: Alessandra Palmisano Marta D'Angelo Ilaria Gandolfini Marco Delsante Giovanni Maria Rossi Micaela Gentile Enrico Fiaccadori Paolo Cravedi Umberto Maggiore Source Type: research
Early recovery of natural killer cells post T-cell depleted allogeneic stem cell transplantation using alemtuzumab "in the bag"
CONCLUSION: This study of ex vivo T-cell depleted SCT's demonstrates that NK cells recover quicker when compared to those receiving unfractionated grafts. These results may have implications for GvHD and the GvL effect which warrants further study.PMID:38641148 | DOI:10.1016/j.trim.2024.102045 (Source: Transplant Immunology)
Source: Transplant Immunology - April 19, 2024 Category: Transplant Surgery Authors: Glenda M Davison Jessica J Opie Saarah F G Davids Rygana Mohammed Nicolas Novitzky Source Type: research
Beyond prevention: Unveiling the benefits of triple vaccination on COVID-19 severity and resource utilization in solid organ transplant recipients
CONCLUSION: In solid organ transplant recipients with COVID-19, triple vaccination, but not double vaccination, against SARS-CoV-2 was associated with significantly less hospital resource utilization, decreased disease severity, and fewer short-term complications. These real-world data from extensively matched controls support the protective effects of COVID-19 vaccination with boosters in this vulnerable population.PMID:38641149 | DOI:10.1016/j.trim.2024.102048 (Source: Transplant Immunology)
Source: Transplant Immunology - April 19, 2024 Category: Transplant Surgery Authors: Jared R Zhang John C Johnson Richard G Preble Muhammad Mujtaba A Scott Lea Heather L Stevenson Michael Kueht Source Type: research
Clinico-epidemiological characteristics of early- versus late-onset cytomegalovirus disease among renal transplant recipients: A two-decade experience
CONCLUSIONS: Early CMV disease presents more frequently as CMV syndrome while late CMV disease usually manifests itself as tissue invasive disease. Graft loss is more common in patients with late onset of CMV disease.PMID:38565378 | DOI:10.1016/j.trim.2024.102040 (Source: Transplant Immunology)
Source: Transplant Immunology - April 2, 2024 Category: Transplant Surgery Authors: Shuvam Roy Anupma Kaul Dharmendra Singh Bhadhuria Narayan Prasad Atul Garg Rungmei S K Marak Manas Ranjan Patel Manas Ranjan Behera Ravi Shankar Kushwaha Monika Yachha Source Type: research
Clinico-epidemiological characteristics of early- versus late-onset cytomegalovirus disease among renal transplant recipients: A two-decade experience
CONCLUSIONS: Early CMV disease presents more frequently as CMV syndrome while late CMV disease usually manifests itself as tissue invasive disease. Graft loss is more common in patients with late onset of CMV disease.PMID:38565378 | DOI:10.1016/j.trim.2024.102040 (Source: Transplant Immunology)
Source: Transplant Immunology - April 2, 2024 Category: Transplant Surgery Authors: Shuvam Roy Anupma Kaul Dharmendra Singh Bhadhuria Narayan Prasad Atul Garg Rungmei S K Marak Manas Ranjan Patel Manas Ranjan Behera Ravi Shankar Kushwaha Monika Yachha Source Type: research
Clinico-epidemiological characteristics of early- versus late-onset cytomegalovirus disease among renal transplant recipients: A two-decade experience
CONCLUSIONS: Early CMV disease presents more frequently as CMV syndrome while late CMV disease usually manifests itself as tissue invasive disease. Graft loss is more common in patients with late onset of CMV disease.PMID:38565378 | DOI:10.1016/j.trim.2024.102040 (Source: Transplant Immunology)
Source: Transplant Immunology - April 2, 2024 Category: Transplant Surgery Authors: Shuvam Roy Anupma Kaul Dharmendra Singh Bhadhuria Narayan Prasad Atul Garg Rungmei S K Marak Manas Ranjan Patel Manas Ranjan Behera Ravi Shankar Kushwaha Monika Yachha Source Type: research
Clinico-epidemiological characteristics of early- versus late-onset cytomegalovirus disease among renal transplant recipients: A two-decade experience
CONCLUSIONS: Early CMV disease presents more frequently as CMV syndrome while late CMV disease usually manifests itself as tissue invasive disease. Graft loss is more common in patients with late onset of CMV disease.PMID:38565378 | DOI:10.1016/j.trim.2024.102040 (Source: Transplant Immunology)
Source: Transplant Immunology - April 2, 2024 Category: Transplant Surgery Authors: Shuvam Roy Anupma Kaul Dharmendra Singh Bhadhuria Narayan Prasad Atul Garg Rungmei S K Marak Manas Ranjan Patel Manas Ranjan Behera Ravi Shankar Kushwaha Monika Yachha Source Type: research
Clinico-epidemiological characteristics of early- versus late-onset cytomegalovirus disease among renal transplant recipients: A two-decade experience
CONCLUSIONS: Early CMV disease presents more frequently as CMV syndrome while late CMV disease usually manifests itself as tissue invasive disease. Graft loss is more common in patients with late onset of CMV disease.PMID:38565378 | DOI:10.1016/j.trim.2024.102040 (Source: Transplant Immunology)
Source: Transplant Immunology - April 2, 2024 Category: Transplant Surgery Authors: Shuvam Roy Anupma Kaul Dharmendra Singh Bhadhuria Narayan Prasad Atul Garg Rungmei S K Marak Manas Ranjan Patel Manas Ranjan Behera Ravi Shankar Kushwaha Monika Yachha Source Type: research
Clinico-epidemiological characteristics of early- versus late-onset cytomegalovirus disease among renal transplant recipients: A two-decade experience
CONCLUSIONS: Early CMV disease presents more frequently as CMV syndrome while late CMV disease usually manifests itself as tissue invasive disease. Graft loss is more common in patients with late onset of CMV disease.PMID:38565378 | DOI:10.1016/j.trim.2024.102040 (Source: Transplant Immunology)
Source: Transplant Immunology - April 2, 2024 Category: Transplant Surgery Authors: Shuvam Roy Anupma Kaul Dharmendra Singh Bhadhuria Narayan Prasad Atul Garg Rungmei S K Marak Manas Ranjan Patel Manas Ranjan Behera Ravi Shankar Kushwaha Monika Yachha Source Type: research
Clinico-epidemiological characteristics of early- versus late-onset cytomegalovirus disease among renal transplant recipients: A two-decade experience
CONCLUSIONS: Early CMV disease presents more frequently as CMV syndrome while late CMV disease usually manifests itself as tissue invasive disease. Graft loss is more common in patients with late onset of CMV disease.PMID:38565378 | DOI:10.1016/j.trim.2024.102040 (Source: Transplant Immunology)
Source: Transplant Immunology - April 2, 2024 Category: Transplant Surgery Authors: Shuvam Roy Anupma Kaul Dharmendra Singh Bhadhuria Narayan Prasad Atul Garg Rungmei S K Marak Manas Ranjan Patel Manas Ranjan Behera Ravi Shankar Kushwaha Monika Yachha Source Type: research
Clinico-epidemiological characteristics of early- versus late-onset cytomegalovirus disease among renal transplant recipients: A two-decade experience
CONCLUSIONS: Early CMV disease presents more frequently as CMV syndrome while late CMV disease usually manifests itself as tissue invasive disease. Graft loss is more common in patients with late onset of CMV disease.PMID:38565378 | DOI:10.1016/j.trim.2024.102040 (Source: Transplant Immunology)
Source: Transplant Immunology - April 2, 2024 Category: Transplant Surgery Authors: Shuvam Roy Anupma Kaul Dharmendra Singh Bhadhuria Narayan Prasad Atul Garg Rungmei S K Marak Manas Ranjan Patel Manas Ranjan Behera Ravi Shankar Kushwaha Monika Yachha Source Type: research
