Expression of concern: "Inhibition of miR-495-3p ameliorated sevoflurane induced damage through BDNF/ERK/CREB signaling pathways in HT22 cells" [Transplant Immunology, Volume 75, December 2022, 101708]
Transpl Immunol. 2023 Dec;81:101879. doi: 10.1016/j.trim.2023.101879. Epub 2023 Jun 28.NO ABSTRACTPMID:38061835 | DOI:10.1016/j.trim.2023.101879 (Source: Transplant Immunology)
Source: Transplant Immunology - December 7, 2023 Category: Transplant Surgery Source Type: research

Expression of concern: "Inhibition of miR-495-3p ameliorated sevoflurane induced damage through BDNF/ERK/CREB signaling pathways in HT22 cells" [Transplant Immunology, Volume 75, December 2022, 101708]
Transpl Immunol. 2023 Dec;81:101879. doi: 10.1016/j.trim.2023.101879. Epub 2023 Jun 28.NO ABSTRACTPMID:38061835 | DOI:10.1016/j.trim.2023.101879 (Source: Transplant Immunology)
Source: Transplant Immunology - December 7, 2023 Category: Transplant Surgery Source Type: research

Expression of concern: "Inhibition of miR-495-3p ameliorated sevoflurane induced damage through BDNF/ERK/CREB signaling pathways in HT22 cells" [Transplant Immunology, Volume 75, December 2022, 101708]
Transpl Immunol. 2023 Dec;81:101879. doi: 10.1016/j.trim.2023.101879. Epub 2023 Jun 28.NO ABSTRACTPMID:38061835 | DOI:10.1016/j.trim.2023.101879 (Source: Transplant Immunology)
Source: Transplant Immunology - December 7, 2023 Category: Transplant Surgery Source Type: research

Microvascular activation and exocytosis after exposure to the serum from mismatched recipients by using donor microvascular cultures
CONCLUSIONS: This bioassay enables us to detect the activation and exocytosis of donor MVEC elicited by respective sera from mismatched kidney recipients.PMID:38013122 | DOI:10.1016/j.trim.2023.101963 (Source: Transplant Immunology)
Source: Transplant Immunology - November 28, 2023 Category: Transplant Surgery Authors: Qiang Sebastian Shi Xin Jiang Ming Li Jun Fang Zhiqiang Fu Shengyi Zhu Chengyu Wu Qianghe Meng Tun Jie Medhat Askar Source Type: research

Microvascular activation and exocytosis after exposure to the serum from mismatched recipients by using donor microvascular cultures
CONCLUSIONS: This bioassay enables us to detect the activation and exocytosis of donor MVEC elicited by respective sera from mismatched kidney recipients.PMID:38013122 | DOI:10.1016/j.trim.2023.101963 (Source: Transplant Immunology)
Source: Transplant Immunology - November 28, 2023 Category: Transplant Surgery Authors: Qiang Sebastian Shi Xin Jiang Ming Li Jun Fang Zhiqiang Fu Shengyi Zhu Chengyu Wu Qianghe Meng Tun Jie Medhat Askar Source Type: research

Microvascular activation and exocytosis after exposure to the serum from mismatched recipients by using donor microvascular cultures
CONCLUSIONS: This bioassay enables us to detect the activation and exocytosis of donor MVEC elicited by respective sera from mismatched kidney recipients.PMID:38013122 | DOI:10.1016/j.trim.2023.101963 (Source: Transplant Immunology)
Source: Transplant Immunology - November 28, 2023 Category: Transplant Surgery Authors: Qiang Sebastian Shi Xin Jiang Ming Li Jun Fang Zhiqiang Fu Shengyi Zhu Chengyu Wu Qianghe Meng Tun Jie Medhat Askar Source Type: research

Microvascular activation and exocytosis after exposure to the serum from mismatched recipients by using donor microvascular cultures
CONCLUSIONS: This bioassay enables us to detect the activation and exocytosis of donor MVEC elicited by respective sera from mismatched kidney recipients.PMID:38013122 | DOI:10.1016/j.trim.2023.101963 (Source: Transplant Immunology)
Source: Transplant Immunology - November 28, 2023 Category: Transplant Surgery Authors: Qiang Sebastian Shi Xin Jiang Ming Li Jun Fang Zhiqiang Fu Shengyi Zhu Chengyu Wu Qianghe Meng Tun Jie Medhat Askar Source Type: research

Microvascular activation and exocytosis after exposure to the serum from mismatched recipients by using donor microvascular cultures
CONCLUSIONS: This bioassay enables us to detect the activation and exocytosis of donor MVEC elicited by respective sera from mismatched kidney recipients.PMID:38013122 | DOI:10.1016/j.trim.2023.101963 (Source: Transplant Immunology)
Source: Transplant Immunology - November 28, 2023 Category: Transplant Surgery Authors: Qiang Sebastian Shi Xin Jiang Ming Li Jun Fang Zhiqiang Fu Shengyi Zhu Chengyu Wu Qianghe Meng Tun Jie Medhat Askar Source Type: research

Microvascular activation and exocytosis after exposure to the serum from mismatched recipients by using donor microvascular cultures
CONCLUSIONS: This bioassay enables us to detect the activation and exocytosis of donor MVEC elicited by respective sera from mismatched kidney recipients.PMID:38013122 | DOI:10.1016/j.trim.2023.101963 (Source: Transplant Immunology)
Source: Transplant Immunology - November 28, 2023 Category: Transplant Surgery Authors: Qiang Sebastian Shi Xin Jiang Ming Li Jun Fang Zhiqiang Fu Shengyi Zhu Chengyu Wu Qianghe Meng Tun Jie Medhat Askar Source Type: research

Microvascular activation and exocytosis after exposure to the serum from mismatched recipients by using donor microvascular cultures
CONCLUSIONS: This bioassay enables us to detect the activation and exocytosis of donor MVEC elicited by respective sera from mismatched kidney recipients.PMID:38013122 | DOI:10.1016/j.trim.2023.101963 (Source: Transplant Immunology)
Source: Transplant Immunology - November 28, 2023 Category: Transplant Surgery Authors: Qiang Sebastian Shi Xin Jiang Ming Li Jun Fang Zhiqiang Fu Shengyi Zhu Chengyu Wu Qianghe Meng Tun Jie Medhat Askar Source Type: research

Microvascular activation and exocytosis after exposure to the serum from mismatched recipients by using donor microvascular cultures
CONCLUSIONS: This bioassay enables us to detect the activation and exocytosis of donor MVEC elicited by respective sera from mismatched kidney recipients.PMID:38013122 | DOI:10.1016/j.trim.2023.101963 (Source: Transplant Immunology)
Source: Transplant Immunology - November 28, 2023 Category: Transplant Surgery Authors: Qiang Sebastian Shi Xin Jiang Ming Li Jun Fang Zhiqiang Fu Shengyi Zhu Chengyu Wu Qianghe Meng Tun Jie Medhat Askar Source Type: research

Indoleamine 2, 3-dioxygenase-transfected bone marrow-derived mesenchymal stem cells promote corneal allograft survival by inhibiting T cell proliferation: A rat study
CONCLUSION: Our results suggest that IDO-BMSC treatment enhances the direct immunomodulatory effect of corneal allograft transplants in rats, promoting corneal allograft survival by inhibiting the proliferation of CD4+, CD8+, and CD4+CD25-T cells. Therefore, modification of BMSCs by lentivirus-mediated IDO gene transfection may provide a novel strategy for controlling corneal allograft rejection.PMID:38007171 | DOI:10.1016/j.trim.2023.101960 (Source: Transplant Immunology)
Source: Transplant Immunology - November 25, 2023 Category: Transplant Surgery Authors: Hongqin Ke Wenjia Zhang Wenrong Xu Qian Cao Lan Li Hai Liu Source Type: research

Examining the impact of immunosuppressive drugs on antibody-dependent cellular cytotoxicity (ADCC) of human peripheral blood natural killer (NK) cells and gamma delta (gd) T cells
CONCLUSIONS: In conclusion, the findings show that despite differences in the expression levels of CD16, γδT cells like NK cells can be readily activated by engagement with RTX and that in vitro exposure to CsA and TAC (calcineurin inhibitors) had a measurable effect on cytokine production but not degranulation by both NK cells and gdT cells from healthy donors. Finally the observation that in PBMC obtained from LTx recipients, NK cells but not γδT cells exhibited impaired cytokine reponses suggests that transplantation or chronic exposure to ISDs differentially impacts their potential to respond to the introduction of...
Source: Transplant Immunology - November 25, 2023 Category: Transplant Surgery Authors: Sedigheh Jalali Sanda Stankovic Glen P Westall Patrick C Reading Lucy C Sullivan Andrew G Brooks Source Type: research

Indoleamine 2, 3-dioxygenase-transfected bone marrow-derived mesenchymal stem cells promote corneal allograft survival by inhibiting T cell proliferation: A rat study
CONCLUSION: Our results suggest that IDO-BMSC treatment enhances the direct immunomodulatory effect of corneal allograft transplants in rats, promoting corneal allograft survival by inhibiting the proliferation of CD4+, CD8+, and CD4+CD25-T cells. Therefore, modification of BMSCs by lentivirus-mediated IDO gene transfection may provide a novel strategy for controlling corneal allograft rejection.PMID:38007171 | DOI:10.1016/j.trim.2023.101960 (Source: Transplant Immunology)
Source: Transplant Immunology - November 25, 2023 Category: Transplant Surgery Authors: Hongqin Ke Wenjia Zhang Wenrong Xu Qian Cao Lan Li Hai Liu Source Type: research

Examining the impact of immunosuppressive drugs on antibody-dependent cellular cytotoxicity (ADCC) of human peripheral blood natural killer (NK) cells and gamma delta (gd) T cells
CONCLUSIONS: In conclusion, the findings show that despite differences in the expression levels of CD16, γδT cells like NK cells can be readily activated by engagement with RTX and that in vitro exposure to CsA and TAC (calcineurin inhibitors) had a measurable effect on cytokine production but not degranulation by both NK cells and gdT cells from healthy donors. Finally the observation that in PBMC obtained from LTx recipients, NK cells but not γδT cells exhibited impaired cytokine reponses suggests that transplantation or chronic exposure to ISDs differentially impacts their potential to respond to the introduction of...
Source: Transplant Immunology - November 25, 2023 Category: Transplant Surgery Authors: Sedigheh Jalali Sanda Stankovic Glen P Westall Patrick C Reading Lucy C Sullivan Andrew G Brooks Source Type: research