Transitional Cell Carcinoma Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Development of a deep-learning model for classification of LI-RADS major features by using subtraction images of MRI: a preliminary study
ConclusionWe developed an end-to-end deep-learning model that classifies the LI-RADS major features using subtraction MRI images. Our model exhibited satisfactory performance in classifying LI-RADS major features.Graphical Abstract (Source: Abdominal Imaging)
Source: Abdominal Imaging - July 10, 2023 Category: Radiology Source Type: research

Transitional Insight into the RNA-Based Oligonucleotides in Cancer Treatment
Appl Biochem Biotechnol. 2023 Jul 4. doi: 10.1007/s12010-023-04597-5. Online ahead of print.ABSTRACTConventional cancer therapies with chemodrugs suffer from various disadvantages, such as irreversible side effects on the skin, heart, liver, and nerves with even fatal consequences. RNA-based therapeutic is a novel technology which offers great potential as non-toxic, non-infectious, and well-tolerable platform. Herein, we introduce different RNA-based platforms with a special focus on siRNA, miRNA, and mRNA applications in cancer treatment in order to better understand the details of their therapeutic effects. Of note, the...
Source: Applied Biochemistry and Biotechnology - July 4, 2023 Category: Biochemistry Authors: Hamed Tabasi Samaneh Mollazadeh Elham Fazeli Khalil Abnus Seyed Mohammad Taghdisi Mohammad Ramezani Mona Alibolandi Source Type: research

Differences in the pathogenetic characteristics of prostate cancer in the transitional and peripheral zones and the possible molecular biological mechanisms
Since the theory of modern anatomical partitioning of the prostate was proposed, the differences in the incidence and pathological parameters of prostate cancer between the peripheral zone and transition zone have been gradually revealed. It suggests that there are differences in the pathogenic pathways and molecular biology of prostate cancer between different regions of origin. Over the past decade, advances in sequencing technologies have revealed more about molecules, genomes, and cell types specific to the peripheral and transitional zones. In recent years, the innovation of spatial imaging and multiple-parameter magn...
Source: Frontiers in Oncology - June 30, 2023 Category: Cancer & Oncology Source Type: research

The efficacy and timing of adjuvant chemotherapy in upper tract urothelial carcinoma
CONCLUSION: The present study data supported the finding that a platinum-based combination with gemcitabine regimen initiated postoperatively significantly improved OS and CSS in patients with UTUC at stages ≥pT2 (N0-3M0). Furthermore, no survival benefit was evident in patients who started AC within 45 days after RNU compared to those who received AC within 45 to 90 days.PMID:37331821 | DOI:10.1016/j.urolonc.2023.04.025 (Source: Urologic Oncology)
Source: Urologic Oncology - June 18, 2023 Category: Urology & Nephrology Authors: Hailong Li Jie Zhou Renfu Chen Jiawei Zhu Junqi Wang Rumin Wen Source Type: research

Cancers, Vol. 15, Pages 3211: Spatial Transcriptomics Identifies Expression Signatures Specific to Lacrimal Gland Adenoid Cystic Carcinoma Cells
This study provides insights into the molecular and cellular landscape of LGACC, which can inform new, targeted therapies to improve patient outcomes. (Source: Cancers)
Source: Cancers - June 16, 2023 Category: Cancer & Oncology Authors: Acadia H. M. Moeyersoms Ryan A. Gallo Michelle G. Zhang Vasileios Stathias Michelle M. Maeng Dawn Owens Rayan Abou Khzam Yoseph Sayegh Cynthia Maza Sander R. Dubovy David T. Tse Daniel Pelaez Tags: Article Source Type: research

Prevalence and grade of malignancy differences with respect to the area of involvement in multiparametric resonance imaging of the prostate in the diagnosis of prostate cancer using the PI-RADS version 2 classification
ConclusionAlthough the prevalence and grade of malignancy in the TZ is lower than in the PZ, PI-RADS4 and 5-targeted biopsies should not be omitted in this location, but PI-RADS3 could be. (Source: World Journal of Urology)
Source: World Journal of Urology - June 16, 2023 Category: Urology & Nephrology Source Type: research

Metabolome sequencing reveals that PRMT1 promotes the progression of invasive micropapillary carcinoma of the breast and predicts a poor prognosis
This study identified the metabolic type-related features and intermediate transition morphology of IMPC, and the identification of potential targets of PRMT1 is expected to provide a basis for the precise diagnosis and treatment of breast IMPC.PMID:37301537 | DOI:10.1016/j.ajpath.2023.05.010 (Source: The American Journal of Pathology)
Source: The American Journal of Pathology - June 10, 2023 Category: Pathology Authors: Kailiang Wu Weidong Li Hanjiao Liu Chen Niu Qianqian Shi Jingyue Zhang Guangshen Gao Hui Sun Fangfang Liu Li Fu Source Type: research

Metabolome sequencing reveals that PRMT1 promotes the progression of invasive micropapillary carcinoma of the breast and predicts a poor prognosis
This study identified the metabolic type-related features and intermediate transition morphology of IMPC, and the identification of potential targets of PRMT1 is expected to provide a basis for the precise diagnosis and treatment of breast IMPC.PMID:37301537 | DOI:10.1016/j.ajpath.2023.05.010 (Source: Am J Pathol)
Source: Am J Pathol - June 10, 2023 Category: Pathology Authors: Kailiang Wu Weidong Li Hanjiao Liu Chen Niu Qianqian Shi Jingyue Zhang Guangshen Gao Hui Sun Fangfang Liu Li Fu Source Type: research