An in-depth analysis on the effects of body composition in patients receiving neoadjuvant chemotherapy for urothelial cell carcinoma
CONCLUSIONS: Based on our retrospective cohort study, NAC did not affect obesity and FMI, but there was a significant decrease in SMI. Sarcopenic obesity was associated with increased severity of NAC adverse events. As such, the presence of this factor may help predict tolerance of NAC.PMID:38381924 | DOI:10.5489/cuaj.8542 (Source: Canadian Urological Association Journal)
Source: Canadian Urological Association Journal - February 21, 2024 Category: Urology & Nephrology Authors: Landan MacDonald Ricardo A Rendon Myuran Thana Lori Wood Robyn MacFarlane David Bell Jon Duplisea Ross Mason Source Type: research

An in-depth analysis on the effects of body composition in patients receiving neoadjuvant chemotherapy for urothelial cell carcinoma
CONCLUSIONS: Based on our retrospective cohort study, NAC did not affect obesity and FMI, but there was a significant decrease in SMI. Sarcopenic obesity was associated with increased severity of NAC adverse events. As such, the presence of this factor may help predict tolerance of NAC.PMID:38381924 | DOI:10.5489/cuaj.8542 (Source: Canadian Urological Association Journal)
Source: Canadian Urological Association Journal - February 21, 2024 Category: Urology & Nephrology Authors: Landan MacDonald Ricardo A Rendon Myuran Thana Lori Wood Robyn MacFarlane David Bell Jon Duplisea Ross Mason Source Type: research

An in-depth analysis on the effects of body composition in patients receiving neoadjuvant chemotherapy for urothelial cell carcinoma
CONCLUSIONS: Based on our retrospective cohort study, NAC did not affect obesity and FMI, but there was a significant decrease in SMI. Sarcopenic obesity was associated with increased severity of NAC adverse events. As such, the presence of this factor may help predict tolerance of NAC.PMID:38381924 | DOI:10.5489/cuaj.8542 (Source: Canadian Urological Association Journal)
Source: Canadian Urological Association Journal - February 21, 2024 Category: Urology & Nephrology Authors: Landan MacDonald Ricardo A Rendon Myuran Thana Lori Wood Robyn MacFarlane David Bell Jon Duplisea Ross Mason Source Type: research

An in-depth analysis on the effects of body composition in patients receiving neoadjuvant chemotherapy for urothelial cell carcinoma
CONCLUSIONS: Based on our retrospective cohort study, NAC did not affect obesity and FMI, but there was a significant decrease in SMI. Sarcopenic obesity was associated with increased severity of NAC adverse events. As such, the presence of this factor may help predict tolerance of NAC.PMID:38381924 | DOI:10.5489/cuaj.8542 (Source: Canadian Urological Association Journal)
Source: Canadian Urological Association Journal - February 21, 2024 Category: Urology & Nephrology Authors: Landan MacDonald Ricardo A Rendon Myuran Thana Lori Wood Robyn MacFarlane David Bell Jon Duplisea Ross Mason Source Type: research

An in-depth analysis on the effects of body composition in patients receiving neoadjuvant chemotherapy for urothelial cell carcinoma
CONCLUSIONS: Based on our retrospective cohort study, NAC did not affect obesity and FMI, but there was a significant decrease in SMI. Sarcopenic obesity was associated with increased severity of NAC adverse events. As such, the presence of this factor may help predict tolerance of NAC.PMID:38381924 | DOI:10.5489/cuaj.8542 (Source: Canadian Urological Association Journal)
Source: Canadian Urological Association Journal - February 21, 2024 Category: Urology & Nephrology Authors: Landan MacDonald Ricardo A Rendon Myuran Thana Lori Wood Robyn MacFarlane David Bell Jon Duplisea Ross Mason Source Type: research

An in-depth analysis on the effects of body composition in patients receiving neoadjuvant chemotherapy for urothelial cell carcinoma
CONCLUSIONS: Based on our retrospective cohort study, NAC did not affect obesity and FMI, but there was a significant decrease in SMI. Sarcopenic obesity was associated with increased severity of NAC adverse events. As such, the presence of this factor may help predict tolerance of NAC.PMID:38381924 | DOI:10.5489/cuaj.8542 (Source: Canadian Urological Association Journal)
Source: Canadian Urological Association Journal - February 21, 2024 Category: Urology & Nephrology Authors: Landan MacDonald Ricardo A Rendon Myuran Thana Lori Wood Robyn MacFarlane David Bell Jon Duplisea Ross Mason Source Type: research

An in-depth analysis on the effects of body composition in patients receiving neoadjuvant chemotherapy for urothelial cell carcinoma
CONCLUSIONS: Based on our retrospective cohort study, NAC did not affect obesity and FMI, but there was a significant decrease in SMI. Sarcopenic obesity was associated with increased severity of NAC adverse events. As such, the presence of this factor may help predict tolerance of NAC.PMID:38381924 | DOI:10.5489/cuaj.8542 (Source: Canadian Urological Association Journal)
Source: Canadian Urological Association Journal - February 21, 2024 Category: Urology & Nephrology Authors: Landan MacDonald Ricardo A Rendon Myuran Thana Lori Wood Robyn MacFarlane David Bell Jon Duplisea Ross Mason Source Type: research

An in-depth analysis on the effects of body composition in patients receiving neoadjuvant chemotherapy for urothelial cell carcinoma
CONCLUSIONS: Based on our retrospective cohort study, NAC did not affect obesity and FMI, but there was a significant decrease in SMI. Sarcopenic obesity was associated with increased severity of NAC adverse events. As such, the presence of this factor may help predict tolerance of NAC.PMID:38381924 | DOI:10.5489/cuaj.8542 (Source: Canadian Urological Association Journal)
Source: Canadian Urological Association Journal - February 21, 2024 Category: Urology & Nephrology Authors: Landan MacDonald Ricardo A Rendon Myuran Thana Lori Wood Robyn MacFarlane David Bell Jon Duplisea Ross Mason Source Type: research

An in-depth analysis on the effects of body composition in patients receiving neoadjuvant chemotherapy for urothelial cell carcinoma
CONCLUSIONS: Based on our retrospective cohort study, NAC did not affect obesity and FMI, but there was a significant decrease in SMI. Sarcopenic obesity was associated with increased severity of NAC adverse events. As such, the presence of this factor may help predict tolerance of NAC.PMID:38381924 | DOI:10.5489/cuaj.8542 (Source: Canadian Urological Association Journal)
Source: Canadian Urological Association Journal - February 21, 2024 Category: Urology & Nephrology Authors: Landan MacDonald Ricardo A Rendon Myuran Thana Lori Wood Robyn MacFarlane David Bell Jon Duplisea Ross Mason Source Type: research

An in-depth analysis on the effects of body composition in patients receiving neoadjuvant chemotherapy for urothelial cell carcinoma
CONCLUSIONS: Based on our retrospective cohort study, NAC did not affect obesity and FMI, but there was a significant decrease in SMI. Sarcopenic obesity was associated with increased severity of NAC adverse events. As such, the presence of this factor may help predict tolerance of NAC.PMID:38381924 | DOI:10.5489/cuaj.8542 (Source: Canadian Urological Association Journal)
Source: Canadian Urological Association Journal - February 21, 2024 Category: Urology & Nephrology Authors: Landan MacDonald Ricardo A Rendon Myuran Thana Lori Wood Robyn MacFarlane David Bell Jon Duplisea Ross Mason Source Type: research

An in-depth analysis on the effects of body composition in patients receiving neoadjuvant chemotherapy for urothelial cell carcinoma
CONCLUSIONS: Based on our retrospective cohort study, NAC did not affect obesity and FMI, but there was a significant decrease in SMI. Sarcopenic obesity was associated with increased severity of NAC adverse events. As such, the presence of this factor may help predict tolerance of NAC.PMID:38381924 | DOI:10.5489/cuaj.8542 (Source: Canadian Urological Association Journal)
Source: Canadian Urological Association Journal - February 21, 2024 Category: Urology & Nephrology Authors: Landan MacDonald Ricardo A Rendon Myuran Thana Lori Wood Robyn MacFarlane David Bell Jon Duplisea Ross Mason Source Type: research

An in-depth analysis on the effects of body composition in patients receiving neoadjuvant chemotherapy for urothelial cell carcinoma
CONCLUSIONS: Based on our retrospective cohort study, NAC did not affect obesity and FMI, but there was a significant decrease in SMI. Sarcopenic obesity was associated with increased severity of NAC adverse events. As such, the presence of this factor may help predict tolerance of NAC.PMID:38381924 | DOI:10.5489/cuaj.8542 (Source: Canadian Urological Association Journal)
Source: Canadian Urological Association Journal - February 21, 2024 Category: Urology & Nephrology Authors: Landan MacDonald Ricardo A Rendon Myuran Thana Lori Wood Robyn MacFarlane David Bell Jon Duplisea Ross Mason Source Type: research

Cancer Type and Histology Influence Cutaneous Immunotherapy Toxicities: A Multi-Institutional Cohort Study
CONCLUSIONS: The highest rate of cirAEs and subsequent survival benefits were observed in cutaneous malignancies treated with ICIs. This study improves our understanding of patients who are at highest risk of developing cirAEs and would, therefore, benefit from appropriate counseling and closer monitoring by their oncologists and dermatologists throughout their ICI therapy. Limitations include its retrospective nature and cohort from one geography.PMID:38366637 | DOI:10.1093/bjd/ljae053 (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 17, 2024 Category: Dermatology Authors: Guihong Wan Sara Khattab Bonnie W Leung Shijia Zhang Nga Nguyen Matthew Tran Chuck Lin Crystal Chang Nora Alexander Ruple Jairath Jordan Phillipps Kimberly Tang Ahmad Rajeh Leyre Zubiri Steven T Chen Shadmehr Demehri Kun-Hsing Yu Alexander Gusev Shawn G K Source Type: research

Cancer Type and Histology Influence Cutaneous Immunotherapy Toxicities: A Multi-Institutional Cohort Study
CONCLUSIONS: The highest rate of cirAEs and subsequent survival benefits were observed in cutaneous malignancies treated with ICIs. This study improves our understanding of patients who are at highest risk of developing cirAEs and would, therefore, benefit from appropriate counseling and closer monitoring by their oncologists and dermatologists throughout their ICI therapy. Limitations include its retrospective nature and cohort from one geography.PMID:38366637 | DOI:10.1093/bjd/ljae053 (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 17, 2024 Category: Dermatology Authors: Guihong Wan Sara Khattab Bonnie W Leung Shijia Zhang Nga Nguyen Matthew Tran Chuck Lin Crystal Chang Nora Alexander Ruple Jairath Jordan Phillipps Kimberly Tang Ahmad Rajeh Leyre Zubiri Steven T Chen Shadmehr Demehri Kun-Hsing Yu Alexander Gusev Shawn G K Source Type: research

Cancer Type and Histology Influence Cutaneous Immunotherapy Toxicities: A Multi-Institutional Cohort Study
CONCLUSIONS: The highest rate of cirAEs and subsequent survival benefits were observed in cutaneous malignancies treated with ICIs. This study improves our understanding of patients who are at highest risk of developing cirAEs and would, therefore, benefit from appropriate counseling and closer monitoring by their oncologists and dermatologists throughout their ICI therapy. Limitations include its retrospective nature and cohort from one geography.PMID:38366637 | DOI:10.1093/bjd/ljae053 (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 17, 2024 Category: Dermatology Authors: Guihong Wan Sara Khattab Bonnie W Leung Shijia Zhang Nga Nguyen Matthew Tran Chuck Lin Crystal Chang Nora Alexander Ruple Jairath Jordan Phillipps Kimberly Tang Ahmad Rajeh Leyre Zubiri Steven T Chen Shadmehr Demehri Kun-Hsing Yu Alexander Gusev Shawn G K Source Type: research