Predictors of long-term renal function after kidney surgery for patients with preoperative chronic kidney disease.
Abstract INTRODUCTION: We evaluated the trajectory of estimated glomerular filtration rate (eGFR) after kidney surgery in patients with kidney cancer and chronic kidney disease (CKD). METHODS: We identified 1204 consecutive patients in our institutional database with preoperative CKD undergoing partial or radical nephrectomy from 1998-2016. Postoperative eGFR was tracked, with patients censored when receiving dialysis or kidney transplantation. A multivariable mixed-effects models assessed associations between preoperative baseline patient and tumor characteristics, and longitudinal eGFR. The Kaplan-Meier met...
Source: Canadian Urological Association Journal - July 27, 2020 Category: Urology & Nephrology Authors: Silagy A, Zabor E, Mano R, DiNatale R, Marcon J, Kashani M, Blum K, Reznik E, Jaimes E, Coleman J, Hakimi AA, Russo P Tags: Can Urol Assoc J Source Type: research

Clinical characteristics and outcomes for young patients with advanced urothelial carcinoma.
PMID: 32744994 [PubMed - as supplied by publisher] (Source: Canadian Urological Association Journal)
Source: Canadian Urological Association Journal - July 27, 2020 Category: Urology & Nephrology Authors: Chehroudi AC, Lavoie JM, Black PC, Eigl BJ Tags: Can Urol Assoc J Source Type: research

A scoping review of the clinical efficacy and safety of the novel thulium fiber laser: The rising star of laser lithotripsy.
CONCLUSIONS: The TFL has the potential to catalyze a paradigm shift in laser lithotripsy. While the objective of this scoping review was to describe the contemporary landscape of the literature, it is important to consider that inferences posed by the studies described herein must be tempered by the low quality of available evidence. PMID: 32744995 [PubMed - as supplied by publisher] (Source: Canadian Urological Association Journal)
Source: Canadian Urological Association Journal - July 27, 2020 Category: Urology & Nephrology Authors: Gao B, Bobrowski A, Lee J Tags: Can Urol Assoc J Source Type: research

Refusal of surgery: A case-based review of ethical and legal principles behind informed consent in Canada.
PMID: 32744996 [PubMed - as supplied by publisher] (Source: Canadian Urological Association Journal)
Source: Canadian Urological Association Journal - July 27, 2020 Category: Urology & Nephrology Authors: Garas SN, Witherspoon L, Lukich N, Abdi H, Breau RH Tags: Can Urol Assoc J Source Type: research

Comprehensive assessment of the morbidity of renal mass biopsy: A population-based assessment of biopsy-related complications.
Abstract INTRODUCTION: We sought to assess seven-day and 30-day complications following renal mass biopsy (RMB), including mortality, hospitalizations, emergency department (ED) visits, and operative and non-operative complications and compare these to rates in population matched controls. METHODS: We performed a population-based, matched, retrospective cohort study of patients undergoing RMB following consultation with a urologist and axial imaging from 2003-2015 in Ontario, Canada. Data on seven-day and 30-day rates of mortality, operative and non operative complications after RMB were reported. The seven-d...
Source: Canadian Urological Association Journal - July 27, 2020 Category: Urology & Nephrology Authors: Garbens A, Wallis CJD, Klaassen Z, Saskin R, Plumptre L, Kodama R, Herschorn S, Nam RK Tags: Can Urol Assoc J Source Type: research

A cross-sectional comparison of secondary polycythemia in testosterone-deficient men treated with nasal testosterone gel vs. intramuscular testosterone cypionate.
CONCLUSIONS: The prevalence of polycythemia in men treated with Natesto was markedly lower compared to the men who received TC therapy. PMID: 32744998 [PubMed - as supplied by publisher] (Source: Canadian Urological Association Journal)
Source: Canadian Urological Association Journal - July 27, 2020 Category: Urology & Nephrology Authors: Best JC, Gonzalez D, Masterson TA, Blachman-Braun R, Pai R, Ramasamy R Tags: Can Urol Assoc J Source Type: research

A drug-coated balloon treatment for urethral stricture disease: Two-year results from the ROBUST I study.
This study investigates the safety and efficacy of the Optilume™ paclitaxel-coated balloon for the treatment of recurrent strictures. METHODS: Men with recurrent bulbar strictures ≤2 cm with 1-4 prior endoscopic treatments were treated with the Optilume™ drug-coated balloon. Patients were evaluated within 14 days, three, six, 12, and 24 months post-treatment. The primary safety endpoint was serious urinary adverse events. The primary efficacy endpoint was ≥50% improvement in International Prostate Symptom Score (IPSS) at 24 months. Secondary outcomes included quality of life, erectile function, flow ...
Source: Canadian Urological Association Journal - July 27, 2020 Category: Urology & Nephrology Authors: Mann RA, Virasoro R, DeLong JM, Estrella RE, Pichardo M, Lay RR, Espino G, Roth JD, Elliott SP Tags: Can Urol Assoc J Source Type: research

Comparison of a magnetic retrieval device vs. flexible cystoscopy for removal of ureteral stents in renal transplant patients: A randomized controlled trial.
CONCLUSIONS: USSQ scores suggest that stent removal with the Black-Star magnetic stent is as equally well-tolerated as flexible cystoscopy by renal transplant patients. Black-Star stent removal was significantly faster than conventional stents. No differences in discomfort, infection rate, or complication rate were found. Use of the Black-Star stent resulted in an estimated annual savings of $27 360 CAD at our centre. PMID: 32745000 [PubMed - as supplied by publisher] (Source: Canadian Urological Association Journal)
Source: Canadian Urological Association Journal - July 27, 2020 Category: Urology & Nephrology Authors: Kapoor A, Akerman J, C L Wong E, Vasisth G, Hassan F, Tajzler C, Piercey K, Hoogenes J, Lambe S Tags: Can Urol Assoc J Source Type: research

Testosterone therapy: Prescribing and monitoring patterns of practice in British Columbia.
CONCLUSIONS: Many men prescribed TTh did not continue beyond a short trial. While the practice of checking pre-and post-TTh testosterone levels has improved over the study period, it is concerning that only one-third had a followup serum testosterone level, and half remained biochemically low. Further education is required around TTh prescribing, dose titration, and monitoring to ensure both effective and safe prescribing practice. PMID: 32745001 [PubMed - as supplied by publisher] (Source: Canadian Urological Association Journal)
Source: Canadian Urological Association Journal - July 27, 2020 Category: Urology & Nephrology Authors: Locke JA, Flannigan R, Günther OP, Skeldon S, Goldenberg SL Tags: Can Urol Assoc J Source Type: research

Defining postoperative ileus and associated risk factors in patients undergoing radical cystectomy with an Enhanced Recovery After Surgery (ERAS) program.
In this study, we aimed to evaluate risk factors that contribute to POI in a cohort of patients managed with a comprehensive Enhanced Recovery After Surgery (ERAS) protocol. METHODS: A retrospective review of consecutive patients who underwent RC from March 2015 to December 2016 at Vancouver General Hospital was performed. POI was defined a priori as insertion of nasogastric tube for nausea or vomiting, or failure to advance to a solid diet by the seventh postoperative day. To illustrate heterogeneity in previous studies, we also evaluated POI using other previously reported definitions in the RC literature. The influ...
Source: Canadian Urological Association Journal - July 27, 2020 Category: Urology & Nephrology Authors: Forbes CM, Chehroudi AC, Mannas M, Bisaillon A, Hong T, So A, Mayson K, Black PC Tags: Can Urol Assoc J Source Type: research

Daily use of a muscle pump activator device reduces duration of hospitalization and improves early graft outcomes post-kidney transplantation: A randomized controlled trial.
CONCLUSIONS: Postoperative use of the MPA device increases urine output, decreases leg edema, minimizes weight gain, and decreases duration of hospitalization after kidney transplantation. A larger and longer-term trial is needed to evaluate the impact on graft function. PMID: 32745003 [PubMed - as supplied by publisher] (Source: Canadian Urological Association Journal)
Source: Canadian Urological Association Journal - July 27, 2020 Category: Urology & Nephrology Authors: Xie W, Levine MA, Aquil S, Pacoli K, Al-Ogaili R, Luke PP, Sener A Tags: Can Urol Assoc J Source Type: research

Diagnostic utility of axial imaging in the evaluation of hematuria: A systematic review and critical appraisal of the literature.
CONCLUSIONS: Lack of granularity in the available literature, particularly with regards to patients with unspecified hematuria severity, limits the generalizability of these results and highlights the need for future studies that provide sufficient baseline information allowing for firmer conclusions to be drawn. PMID: 32745004 [PubMed - as supplied by publisher] (Source: Canadian Urological Association Journal)
Source: Canadian Urological Association Journal - July 27, 2020 Category: Urology & Nephrology Authors: Wallis CJD, Sayyid RK, Manyevitch R, Perlis N, Lokeshwar VB, Fleshner NE, Terris MK, Nielsen ME, Klaassen Z Tags: Can Urol Assoc J Source Type: research

Peritoneal and port-site metastasis following robotic-assisted radical prostatectomy.
PMID: 32701435 [PubMed - as supplied by publisher] (Source: Canadian Urological Association Journal)
Source: Canadian Urological Association Journal - July 17, 2020 Category: Urology & Nephrology Authors: O'Connor E, Timm B, Chislett B, Teh J, Lawrentschuk N, Murphy DG, Bolton D Tags: Can Urol Assoc J Source Type: research

The scope, presentation, and management of genitourinary complications in patients presenting with high-grade urethral complications after radiotherapy for prostate cancer.
CONCLUSIONS: Urethral complications related to prostate RT are seldom an isolated problem and require a substantial amount of urological resources and interventions. PMID: 32701436 [PubMed - as supplied by publisher] (Source: Canadian Urological Association Journal)
Source: Canadian Urological Association Journal - July 17, 2020 Category: Urology & Nephrology Authors: Doiron RC, Witten J, Rourke KF Tags: Can Urol Assoc J Source Type: research

Comparison of micro-ultrasound and multiparametric magnetic resonance imaging for prostate cancer: A multicenter, prospective analysis.
CONCLUSIONS: In this initial multicenter registry, micro-ultrasound had comparable or higher sensitivity for clinically significant prostate cancer compared to mpMRI, with similar specificity. Micro-ultrasound is a low-cost, single-session option for prostate screening and targeted biopsy. Further larger-scale studies are required for validation of these findings. PMID: 32701437 [PubMed - as supplied by publisher] (Source: Canadian Urological Association Journal)
Source: Canadian Urological Association Journal - July 17, 2020 Category: Urology & Nephrology Authors: Klotz L, Lughezzani G, Maffei D, Sánchez A, Pereira JG, Staerman F, Cash H, Luger F, Lopez L, Sanchez-Salas R, Abouassaly R, Shore ND, Eure G, Paciotti M, Astobieta A, Wiemer L, Hofbauer S, Heckmann R, Gusenleitner A, Kaar J, Mayr C, Loidl W, Rouffilange Tags: Can Urol Assoc J Source Type: research

Images - Para-aortic lymphatic ectasia suggestive of testicular cancer retroperitoneal metastasis.
PMID: 32701438 [PubMed - as supplied by publisher] (Source: Canadian Urological Association Journal)
Source: Canadian Urological Association Journal - July 17, 2020 Category: Urology & Nephrology Authors: Chahine S, Toren P Tags: Can Urol Assoc J Source Type: research

Re-operation within 30 days of radical cystectomy: Identifying high-risk patients and complications using ACS-NSQIP database.
CONCLUSIONS: Recognizing increasing BMI, COPD, and African-American race as risk factors for re-operation within 30 days of RC will allow urologists to preoperatively identify such high-risk patients and prompt them to adopt more aggressive approaches to minimize postoperative surgical complications. PMID: 32701439 [PubMed - as supplied by publisher] (Source: Canadian Urological Association Journal)
Source: Canadian Urological Association Journal - July 17, 2020 Category: Urology & Nephrology Authors: Sayyid RK, Magee D, Hird AE, Harper BT, Webb E, Fratino KL, Terris MK, Madi R, Satkunasivam R, Wallis CJD, Klaassen Z Tags: Can Urol Assoc J Source Type: research

Heterogeneity in urology teaching curricula among Canadian urology residency programs.
CONCLUSIONS: Although most program directors prioritize the review of chapters in the core urology textbook, we found significant heterogeneity in the teaching sessions prioritized and offered in current urology residency curricula. As we move to standardize the quality of graduating trainees, understanding the impact of variable educational opportunities on residency training may become increasingly important. PMID: 32701440 [PubMed - as supplied by publisher] (Source: Canadian Urological Association Journal)
Source: Canadian Urological Association Journal - July 17, 2020 Category: Urology & Nephrology Authors: Mann U, Ramjiawan R, Nayak JG, Patel P Tags: Can Urol Assoc J Source Type: research

Predictors of prostate bed recurrence on magnetic resonance imaging in patients with rising prostate-specific antigen after radical prostatectomy.
CONCLUSIONS: African-American patients with biochemical failure after RP are less likely to have MRI-detectable recurrence in the prostate bed compared with White patients. PMID: 32701441 [PubMed - as supplied by publisher] (Source: Canadian Urological Association Journal)
Source: Canadian Urological Association Journal - July 17, 2020 Category: Urology & Nephrology Authors: Nasser NJ, Chernyak V, Shankar V, Garg M, Bodner W, Kalnicki S, Klein J Tags: Can Urol Assoc J Source Type: research

The risk of stress incontinence after urethral surgery in women.
PMID: 32701442 [PubMed - as supplied by publisher] (Source: Canadian Urological Association Journal)
Source: Canadian Urological Association Journal - July 17, 2020 Category: Urology & Nephrology Authors: Law J, Welk B Tags: Can Urol Assoc J Source Type: research

Men's health in Canada: A national survey of urologists.
PMID: 32701443 [PubMed - as supplied by publisher] (Source: Canadian Urological Association Journal)
Source: Canadian Urological Association Journal - July 17, 2020 Category: Urology & Nephrology Authors: Punjani N, Di Pierdomenico A, Goldenberg L, Brock G, Flannigan R Tags: Can Urol Assoc J Source Type: research

Stone clearance times with mini-percutaneous nephrolithotomy: Comparison of a 1.5 mm ballistic/ultrasonic mini-probe vs. laser.
Abstract INTRODUCTION: A limitation of mini-percutaneous nephrolithotomy (mPCNL) is the narrow working channel of mini-nephroscopes, typically restricting instrumentation to 5 F or smaller. We evaluated the efficacy of the 1.5 mm Swiss Lithoclast® Trilogy (Trilogy) rigid probe and compared the results to consecutive cases performed with a 30 W Holmium:YAG (Ho:YAG) laser. METHODS: A retrospective review of 30 consecutive mPCNL cases using the Trilogy and 30 W Holmium laser was performed. A 12-French (F) MIPS nephroscope with a 16.5 F access sheath and 6.7 F working channel was used for all mPCNL cases. The...
Source: Canadian Urological Association Journal - July 17, 2020 Category: Urology & Nephrology Authors: Timm B, Farag M, Davis NF, Webb D, Angus D, Troy A, Bolton D, Jack G Tags: Can Urol Assoc J Source Type: research

A systematic review and meta-analysis of the long-term outcomes of ileal conduit and orthotopic neobladder urinary diversion.
Abstract INTRODUCTION: We aimed to perform a systematic review and meta-analysis on the long-term durability, incidence of complications, and patient satisfaction outcomes in ileal conduit (IC) and orthotopic neobladder (ONB). METHODS: A systematic electronic literature search was performed in Medline, Embase, Cochrane Library, and Scopus using MeSH and free-text search terms "Urinary diversion" AND "Ileal conduit" AND "Neobladder." The search concluded June 19, 2018. Inclusion criteria were those patients who had a cystectomy and required urinary diversion by either IC or neobla...
Source: Canadian Urological Association Journal - July 17, 2020 Category: Urology & Nephrology Authors: Browne E, Lawrentschuk N, Davis NF Tags: Can Urol Assoc J Source Type: research

Active surveillance before radiotherapy - outcome and predictive factors for multiple biopsies before treatment.
CONCLUSIONS: In our experience, radiotherapy after a period of AS, even with Gleason grade progression, did not lead to worse outcomes compared to patients who had radiotherapy after only one biopsy. PMID: 32701446 [PubMed - as supplied by publisher] (Source: Canadian Urological Association Journal)
Source: Canadian Urological Association Journal - July 17, 2020 Category: Urology & Nephrology Authors: Alcaidinho A, Delouya G, Bahary JP, Saad F, Taussky D Tags: Can Urol Assoc J Source Type: research

Mesenchymal stem cells ameliorate partial bladder outlet obstruction-induced epithelialmesenchymal transition type II independent of mast cell recruitment and degranulation.
CONCLUSIONS: Our results demonstrate the involvement of EMT type II in the pathophysiology of pBOO and confirm its mitigation with MSC treatment independent of mast cells response. The observations provide insight into the mechanism of action and have therapeutic ramifications. PMID: 32701447 [PubMed - as supplied by publisher] (Source: Canadian Urological Association Journal)
Source: Canadian Urological Association Journal - July 17, 2020 Category: Urology & Nephrology Authors: Kadam R, Wiafe B, Metcalfe PD Tags: Can Urol Assoc J Source Type: research

Pediatric urological surgery readiness condition (PedsUROCON).
PMID: 32631479 [PubMed] (Source: Canadian Urological Association Journal)
Source: Canadian Urological Association Journal - July 1, 2020 Category: Urology & Nephrology Authors: Ferreira R, Keefe D, Wang Y, McGrath M, Koyle MA, Siemens DR, Braga LH Tags: Can Urol Assoc J Source Type: research

Male genitalia injuries: Unspoken collateral damage from the COVID-19 pandemic.
PMID: 32631480 [PubMed] (Source: Canadian Urological Association Journal)
Source: Canadian Urological Association Journal - July 1, 2020 Category: Urology & Nephrology Authors: Spooner J, Lee L, Kinahan J, Metcalfe M, Hoag N Tags: Can Urol Assoc J Source Type: research

Discrepancy in pathology reports upon second review of radical orchiectomy specimens for testicular germ cell tumors.
CONCLUSIONS: Only 10% of orchiectomy specimens underwent a second pathology review, with nearly 40% of reviews leading to a meaningful change in parameters. Such variation could lead to incorrect tumor staging, estimate of relapse risk, and inappropriate treatment decisions. Expert pathology review of RO specimens should be considered, as it has significant implications for decision making. PMID: 32574142 [PubMed - as supplied by publisher] (Source: Canadian Urological Association Journal)
Source: Canadian Urological Association Journal - June 16, 2020 Category: Urology & Nephrology Authors: Nason GJ, Sweet J, Landoni L, Leao R, Anson-Cartwright L, Mok S, Guzylak V, D'Angelo A, Fang ZY, Geist I, Warde P, Jewett MAS, Hamilton RJ Tags: Can Urol Assoc J Source Type: research

Shared decision-making for the management of small renal masses - development and acceptability testing of a novel patient decision aid.
CONCLUSIONS: A novel patient decision aid was created to facilitate shared decision-making for management of SRMs. This clinical tool was acceptable with patients, patient advocates, and urologists and is freely available at: https://decisionaid.ohri.ca/decaids.html. PMID: 32574143 [PubMed - as supplied by publisher] (Source: Canadian Urological Association Journal)
Source: Canadian Urological Association Journal - June 16, 2020 Category: Urology & Nephrology Authors: McAlpine K, Breau RH, Stacey D, Knee C, Jewett MAS, Violette PD, Richard PO, Cagiannos I, Morash C, Lavallée LT Tags: Can Urol Assoc J Source Type: research

Surveillance post-radiofrequency ablation for small renal masses: Recurrence and followup.
Abstract INTRODUCTION: Small renal masses (SRMs), enhancing tumors
Source: Canadian Urological Association Journal - June 16, 2020 Category: Urology & Nephrology Authors: Lam CJ, Wong NC, Voss M, Mironov O, Connolly M, Matsumoto E, Kapoor A Tags: Can Urol Assoc J Source Type: research

Factors predicting early mortality after radical cystectomy for urothelial carcinoma in a contemporary cohort of patients.
Abstract INTRODUCTION: We aimed to identify preoperatively available patient variables associated with increased mortality within 30 and 90 days of radical cystectomy (RC) for localized urothelial carcinoma (UC), and to evaluate temporal trends in early mortality rates. METHODS: We reviewed the National Cancer Database to identify patients who underwent RC for UC between 2006 and 2013. Preoperatively available patient-specific demographics and mortality rates at 30 and 90 days postoperatively were analyzed. Univariable and multivariable logistic regression analyses were performed to examine factors associated...
Source: Canadian Urological Association Journal - June 16, 2020 Category: Urology & Nephrology Authors: Kim S, Kokorovic A, Sharma V, Boorjian S, Rendon RA, Bell D, Mason R Tags: Can Urol Assoc J Source Type: research

Improved artificial urinary sphincter outcomes using a transcorporal cuff placement in patients with a "fragile urethra".
CONCLUSIONS: AUS insertion is an effective treatment option for post-prostatectomy incontinence in the setting of a fragile urethra. Transcorporal cuff placement in this subset of patients may be recommended, as it is associated with lower revision and erosion rates compared to standard cuff placement. PMID: 32569562 [PubMed - as supplied by publisher] (Source: Canadian Urological Association Journal)
Source: Canadian Urological Association Journal - June 16, 2020 Category: Urology & Nephrology Authors: Redmond EJ, Rourke KF, Tong S, Zemp L, Hoy N Tags: Can Urol Assoc J Source Type: research

Bipolar vs. monopolar transurethral resection of the prostate for lower urinary tract symptoms secondary to benign prostatic obstruction: A Cochrane review.
CONCLUSIONS: BTURP and MTURP probably improve urological symptoms to a similar degree. BTURP probably reduces TUR syndrome and blood transfusion slightly postoperatively. The moderate certainty of evidence available for primary outcomes suggests no need for further RCTs comparing BTURP and MTURP. PMID: 32569563 [PubMed - as supplied by publisher] (Source: Canadian Urological Association Journal)
Source: Canadian Urological Association Journal - June 16, 2020 Category: Urology & Nephrology Authors: Alexander CE, Scullion MMF, Omar MI, Yuan Y, Mamoulakis C, N'Dow JMO, Chen C, Lam TBL Tags: Can Urol Assoc J Source Type: research

Long-term outcomes after radical or partial nephrectomy for T1a renal cell carcinoma: A population-based study.
CONCLUSIONS: Our study found that in patients undergoing surgery for T1a RCC, PN was associated with improved OS and reduced risk of CKD compared to RN. However, few patients in either group developed ESRD requiring renal replacement therapy. PMID: 32569564 [PubMed - as supplied by publisher] (Source: Canadian Urological Association Journal)
Source: Canadian Urological Association Journal - June 16, 2020 Category: Urology & Nephrology Authors: Nayan M, Saarela O, Lawson K, Martin L, Komisarenko M, Finelli A Tags: Can Urol Assoc J Source Type: research

Deficits in urological knowledge and skills among family medicine residents in Canada.
CONCLUSIONS: There are significant deficiencies in urological knowledge and skills among family medicine residents in Canada, possibly as a consequence of insufficient educational experiences during medical training. PMID: 32569565 [PubMed - as supplied by publisher] (Source: Canadian Urological Association Journal)
Source: Canadian Urological Association Journal - June 16, 2020 Category: Urology & Nephrology Authors: Redmond EJ, Saleem S, Domes TS, Rourke KF Tags: Can Urol Assoc J Source Type: research

Canadian experience of neoadjuvant chemotherapy on bladder recurrences in patients managed with trimodal therapy for muscle-invasive bladder cancer.
CONCLUSIONS: Receipt of NAC does not obviate the risk of bladder recurrence post-TMT. Patients with CIS should be monitored especially closely for local recurrence. PMID: 32569566 [PubMed - as supplied by publisher] (Source: Canadian Urological Association Journal)
Source: Canadian Urological Association Journal - June 16, 2020 Category: Urology & Nephrology Authors: Ajib K, Tjong MC, Tan GH, Nason G, Berjaoui MB, Erlich A, Maganti M, Sridhar S, Fleshner NE, Zlotta AR, Catton C, Berlin A, Chung P, Kulkarni GS Tags: Can Urol Assoc J Source Type: research

Are basic robotic surgical skills transferable from the simulator to the operating room? A randomized, prospective, educational study.
CONCLUSIONS: Objective assessments of urology residents on the da Vinci Surgical Skills Simulator tasks ring and rail 2 and suture sponge correlated with their objective assessments of bladder mobilization and urethro-vesical anastomosis. Therefore, basic robotic skills could be transferred from the simulator to the operating room. PMID: 32569567 [PubMed - as supplied by publisher] (Source: Canadian Urological Association Journal)
Source: Canadian Urological Association Journal - June 16, 2020 Category: Urology & Nephrology Authors: Almarzouq A, Hu J, Noureldin YA, Yin A, Anidjar M, Bladou F, Tanguay S, Kassouf W, Aprikian AG, Andonian S Tags: Can Urol Assoc J Source Type: research

Real-world evidence in patient-reported outcomes (PROs) of metastatic castrate-resistant prostate cancer (mCRPC) patients treated with abiraterone acetate + prednisone (AA+P) across Canada: Final results of COSMiC.
CONCLUSIONS: COSMiC represents the largest Canadian mCRPC cohort treated with AA+P with real-world, prospective evaluation of PROs. This data demonstrated the maintenance in quality of life and cognitive status over the course of the study and underscores the importance of PRO use in this complex patient population. PMID: 32569568 [PubMed - as supplied by publisher] (Source: Canadian Urological Association Journal)
Source: Canadian Urological Association Journal - June 16, 2020 Category: Urology & Nephrology Authors: Gotto G, Drachenberg DE, Chin J, Casey R, Fradet V, Sabbagh R, Shayegan B, Rendon RA, Danielson B, Camacho F, Zardan A, Plante R, Hew H, Chan K, Feifer A Tags: Can Urol Assoc J Source Type: research

The history of renal transplantation in Canada.
Abstract While the urologist's involvement in kidney transplantation varies from center to center and country to country, urologists remain integral to many programs across Canada. From the early days of kidney transplant to contemporary times, the leadership, vision, and skillset of Canadian urologists have helped progress the field. In this review of Canadian urologists' role in kidney transplantation, the achievements of this professional group are highlighted and celebrated. Original contributors to the field, as well as notable achievements are highlighted, with a focus on the impact of Canadian urologists. ...
Source: Canadian Urological Association Journal - June 16, 2020 Category: Urology & Nephrology Authors: Levine MA, Chin JL, Rasmussen A, Sener A, Luke P Tags: Can Urol Assoc J Source Type: research

An evaluation of the role of tumor load in cytoreductive nephrectomy.
CONCLUSIONS: Primary tumor volume was significant for predicting OS, while the fraction of disease resected did not appear to impact upon patient outcomes. Although rich in detail, our study is potentially limited by selection bias. Future temporal studies may help elucidate whether the primary tumor shape is associated with tumor growth kinetics. PMID: 32569570 [PubMed - as supplied by publisher] (Source: Canadian Urological Association Journal)
Source: Canadian Urological Association Journal - June 16, 2020 Category: Urology & Nephrology Authors: Silagy AW, Duzgol C, Marcon J, DiNatale RG, Mano R, Blum KA, Reznik E, Voss MH, Motzer RJ, Coleman JA, Russo P, Akin O, Hakimi AA Tags: Can Urol Assoc J Source Type: research

The history of cryosurgery in Canada: A tale of two cities.
This article chronicles the development of the two programs and outlines the scientific and clinical contributions by investigators at the two centers. PMID: 32569572 [PubMed - as supplied by publisher] (Source: Canadian Urological Association Journal)
Source: Canadian Urological Association Journal - June 16, 2020 Category: Urology & Nephrology Authors: Chin JL, Donnelly BJ, Nair SM, Lavi A Tags: Can Urol Assoc J Source Type: research

Early adaptation of urology residency educational programs during COVID-19 clinical and gathering restrictions.
PMID: 32569574 [PubMed - as supplied by publisher] (Source: Canadian Urological Association Journal)
Source: Canadian Urological Association Journal - June 16, 2020 Category: Urology & Nephrology Authors: Gabara A, Visram K, Leveridge M Tags: Can Urol Assoc J Source Type: research

Canadian Update on Surgical Procedures (CUSP) Urology Group consensus for intraoperative hemostasis during minimally invasive partial nephrectomy.
CONCLUSIONS: Given the variability in tumor size, depth, location, and vascularity, coupled with limitations of laparoscopic equipment, achieving consistent hemostasis in MIPN may be challenging. Despite over two decades of MIPN experience, limited evidence exists to guide clinicians. Through a three-step Delphi method and rigorous iterative review with a panel of experts, we ascertained a guiding checklist of principles for newly beginning and practicing urologists to reference. PMID: 32569571 [PubMed - as supplied by publisher] (Source: Canadian Urological Association Journal)
Source: Canadian Urological Association Journal - June 9, 2020 Category: Urology & Nephrology Authors: Cheung DC, Wallis CJD, Possee S, Tajzler C, Anidjar M, Barrett K, Deklaj T, Drachenberg DE, Evans H, French C, Gotto G, Izard J, Jain U, Kawakami J, Kulkarni GS, Lee J, McCracken J, McGregor T, Richard PO, Rowe NE, Sabbagh R, St Martin B, Tatzel S, Touma Tags: Can Urol Assoc J Source Type: research

Controversies in the management of clinical stage 1 testis cancer.
The objective was to distill through discussion around cases, expert approach to working through these challenges. Herein we present a summary of discussion from the workshop around controversies in the management of clinical stage 1 (CS1) disease. CS1 represents organ confined non-metastatic testis cancer that represents approximately 70-80% of men at presentation. Regardless of management, CS1 has an excellent prognosis. However, without adjuvant treatment, approximately 30% of CS1 nonseminomatous germ cell tumors (NSGCT) and 15% of CS1 seminoma relapse. The workshop reviewed that while surveillance has become the standa...
Source: Canadian Urological Association Journal - June 9, 2020 Category: Urology & Nephrology Authors: Nason GJ, Chung P, Warde P, Huddart R, Albers P, Kollmannsberger C, Booth CM, Hansen AR, Bedard PL, Einhorn L, Nichols C, Rendon RA, Wood L, Jewett MAS, Hamilton RJ Tags: Can Urol Assoc J Source Type: research

Bone scan use in the management of metastatic castration-resistant prostate cancer: Survey of practice patterns among Canadian radiation oncologists, medical oncologists, and urologists.
PMID: 32520699 [PubMed - as supplied by publisher] (Source: Canadian Urological Association Journal)
Source: Canadian Urological Association Journal - June 5, 2020 Category: Urology & Nephrology Authors: Meem M, Zukotynski K, Raman S, Emmenegger U Tags: Can Urol Assoc J Source Type: research

Images - A series of congenital mesonephric/Wolffian duct abnormalities in the adult and pediatric populations.
PMID: 32520700 [PubMed - as supplied by publisher] (Source: Canadian Urological Association Journal)
Source: Canadian Urological Association Journal - June 5, 2020 Category: Urology & Nephrology Authors: Cooper M, Guiterrez C, Swana H, Rich M, Wiegand L Tags: Can Urol Assoc J Source Type: research

Patients treated for uric acid stones reoccur more often and within a shorter interval in comparison to patients treated for calcium stones.
CONCLUSIONS: UA stone-formers are more likely to have a recurrence and to undergo surgical intervention in comparison to CaOx stone-formers, regardless of MPT. These differences are more prominent during the first year of followup and should be incorporated into the patient's followup protocol. PMID: 32520701 [PubMed - as supplied by publisher] (Source: Canadian Urological Association Journal)
Source: Canadian Urological Association Journal - June 5, 2020 Category: Urology & Nephrology Authors: Nevo A, Levi O, Sidi A, Tsivian A, Baniel J, Margel D, Lifshitz D Tags: Can Urol Assoc J Source Type: research

Morbid obesity is adversely associated with perioperative outcomes in patients undergoing robot-assisted laparoscopic radical prostatectomy.
CONCLUSIONS: Morbid obesity is adversely associated with perioperative outcomes in RALRP. Close management is required in patients undergoing RALRP with morbid obesity for potential worse prognosis. PMID: 32520702 [PubMed - as supplied by publisher] (Source: Canadian Urological Association Journal)
Source: Canadian Urological Association Journal - June 5, 2020 Category: Urology & Nephrology Authors: Han H, Qin Y, Ruan Y, He J, Cao Z, Wei X, Cao Y Tags: Can Urol Assoc J Source Type: research

Impact of the systemic immune-inflammation index for the prediction of prognosis and modification of the risk model in patients with metastatic renal cell carcinoma treated with first-line tyrosine kinase inhibitors.
In this study, we investigated the impact of systemic immune-inflammation index (SII), which is calculated based on neutrophil count, platelet count, and lymphocyte count, on predicting the prognosis in patients with mRCC and its usefulness for re-classification of patients with a more sophisticated risk model. METHODS: From January 2008 to January 2018, 179 mRCC patients with a pretreatment and SII were retrospectively investigated. All patients were classified into either a high-SII group or a low-SII group based on the cutoff value of a SII at 730, as reported in previous studies; the overall survival (OS) rates in...
Source: Canadian Urological Association Journal - June 5, 2020 Category: Urology & Nephrology Authors: Teishima J, Inoue S, Hayashi T, Matsubara A, Mita K, Hasegawa Y, Kato M, Kajiwara M, Shigeta M, Maruyama S, Moriyama H, Fujiwara S Tags: Can Urol Assoc J Source Type: research

Is there a correlation between the aggressiveness of chronic asymptomatic prostatitis NIH category IV and the Gleason score in patients with prostate cancer?
CONCLUSIONS: In prostate cancer patients with CAPNIHIV, there was a positive correlation between the inflammation aggressiveness grade and the ISUP grade. The aggressiveness of intraprostatic inflammation may be an important morphological factor affecting the Gleason score. PMID: 32520704 [PubMed - as supplied by publisher] (Source: Canadian Urological Association Journal)
Source: Canadian Urological Association Journal - June 5, 2020 Category: Urology & Nephrology Authors: Aglamis E, Ceylan C, Akin MM Tags: Can Urol Assoc J Source Type: research